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Molecular Mechanism of Retinoic Acid Action

Institution: The Burnham Institute for Medical Research
Investigator(s): Xiao-Kun Zhang, Ph.D.
Award Cycle: 1992 (Cycle 1) Grant #: 1FT-0030 Award: $75,600
Subject Area: General Biomedical Science
Award Type: Postdoctoral Fellowship Awards
Abstracts
Publications

Ligand-binding domain of thyroid hormone receptors modulates DNA binding and determines their bifunctional roles
Periodical: New Biologist Index Medicus:
Authors: Zhang XK, Wills KN, Graupner Gerhart, et al. ART
Yr: 1991 Vol: 3 Nbr: 2 Abs: Pg: 169-181

Thyroid hormone receptors repress estrogen receptor activation of a TRE
Periodical: Molecular Endocrinology Index Medicus:
Authors: Graupner G, Zhang X, Tzukerman M, et al ART
Yr: 1992 Vol: 5 Nbr: 3 Abs: Pg: 365-372

Regulatory functions of a non-ligand-binding thyorid hormone receptor isoform
Periodical: Index Medicus:
Authors: Hermann T, Zhang X, Tzukerman M, et al ART
Yr: 1992 Vol: 2 Nbr: 7 Abs: Pg: 565-574

Coordinate expression of functionally distinct thyroid hormone receptor alpha isoforms during neonatal brain development
Periodical: Molecular Endocrinology Index Medicus:
Authors: Wills KN, Zhang XK, Pfahl M ART
Yr: 1991 Vol: 5 Nbr: 8 Abs: Pg: 1109-1119

Inhibition of estrogen receptor activity by the tumor promoter 12-O-Tetradeconylphorbol-13-Acetate: a molecular analysis
Periodical: Molecular Endocrinology Index Medicus:
Authors: Tzukerman M, Zhang XK, Pfahl M ART
Yr: 1991 Vol: 5 Nbr: 12 Abs: Pg: 1983-1992

Antagonsism between retinoic acid receptors and AP-1: implications for tumor promotion and inflammation
Periodical: New Biologist Index Medicus:
Authors: Yang-Yen HF, Zhang XK, Graupner G, et al ART
Yr: 1991 Vol: 3 Nbr: 12 Abs: Pg: 1206-1219

DNA binding and dimerization determinants for thyroid hormone receptor alpha and its interaction with a nuclear protein
Periodical: Molecular Endocrinology Index Medicus:
Authors: Zhang XK, Tran PB, Pfahl M ART
Yr: 1991 Vol: 5 Nbr: 12 Abs: Pg: 1909-1920

Novel pathway for thyroid hormone receptor action through interaction with jun and fos oncogene activities
Periodical: Molecular and Cellular Biology Index Medicus:
Authors: Zhang XK, Wills KN, Husmann M, Hermann T, Pfahl M ART
Yr: 1991 Vol: 11 Nbr: 12 Abs: Pg: 6016-6025

Retinoid X receptor is an auxiliary protein for thyorid hormone and retinoic acid receptor
Periodical: Nature Index Medicus:
Authors: Zhang XK, Hoffmann B, Tran PB, Graupner G, Pfahl M ART
Yr: 1992 Vol: 355 Nbr: 6359 Abs: Pg: 441-446

RARgamma2 expression is regulated through a retinoic acid response element embedded in SP1 sites
Periodical: Molecular and Cellular Biology Index Medicus:
Authors: Lehmann JM, Zhang XK, Pfahl M ART
Yr: 1992 Vol: 12 Nbr: Abs: Pg: 2976-2985

Heterodimeric receptor complexes determine T3 and retinoid signaling specificities
Periodical: Molecular Endocrinology Index Medicus:
Authors: Hermann T, Hoffmann B, Zhang XK, Tran P, Pfahl M ART
Yr: 1992 Vol: Nbr: Abs: Pg:

9-cis retinoic acid induces RXR homodimer formation: a mechanism defining a novel retinoid pathway
Periodical: Nature Index Medicus:
Authors: Zhang XK, Lehmann JM, Hoffmann B, et al ART
Yr: 1992 Vol: Nbr: Abs: Pg: