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Local Cytokine Immunotherapy for Lung Cancer

Institution: University of California, Los Angeles
Investigator(s): Steven Dubinett, M.D.
Award Cycle: 1992 (Cycle 1) Grant #: 1KT-0110 Award: $225,000
Subject Area: Cancer
Award Type: New Investigator Awards
Abstracts
Publications

The antitumor and immunoregulatory response to peritumor interleukin 2 immunotherapy for murine lung cancer
Periodical: Proceedings of the American Association for Cancer Research Index Medicus:
Authors: Dubinett SM, Tobias J, Patrone L, et al. ABS
Yr: 1991 Vol: 32 Nbr: Abs: Pg: 247

Wound-infiltrating lymphocytes following surgical adjuvant interleukin 2 immunotherapy for lung cancer
Periodical: American Review of Respiratory Disease Index Medicus:
Authors: Patrone L, Tobias J, McBride WH, Moloney M, Dubinett SM ABS
Yr: 1991 Vol: 143 Nbr: Abs: A231 Pg:

In vivo antitumor response to interleukin-7
Periodical: Clinical Research Index Medicus:
Authors: Kelly DM, McBride WH, Dubinett SM ABS
Yr: 1992 Vol: 40 Nbr: Abs: Pg: 63A

Analysis of IL-2 responsive tumor-infiltrating lymphocytes from basal cell carcinoma
Periodical: Index Medicus:
Authors: Nguyen QH, Yamamoto RA, Tomono S, Dubinett SM, Moy RL ABS
Yr: 1992 Vol: 40 Nbr: Abs: Pg: 12A

The effect of cytokines on lymphocyte endothelial adhesion
Periodical: Index Medicus:
Authors: Kelly D, Lichtenstein A, McBride WH, Dubinett SM ABS
Yr: 1992 Vol: 33 Nbr: Abs: Pg: 296

IL-7 augments IL-2 induced murine LAK cell cytotoxicity and viability
Periodical: Index Medicus:
Authors: Markowitz JA, Yan D, Seelig M, Dubinett SM ABS
Yr: 1992 Vol: 33 Nbr: Abs: Pg: 325

Interleukin-2-responsive wound-infiltrating lymphocytes in surgical adjuvant cancer immunotherapy
Periodical: Immunological Investigations Index Medicus:
Authors: Dubinett SM, Patrone L, Huang M, et al ART
Yr: 1993 Vol: 22 Nbr: 1 Abs: Pg: 13-23

Intratumoral interleukin-2 immunotherapy: activation of tumor-infiltrating and splenic lymphocytes in vivo
Periodical: Index Medicus:
Authors: Dubinett SM, Patrone L, Tobias J, Cochran AJ, Wen DR, McBride WH ART
Yr: 1993 Vol: 36 Nbr: 3 Abs: Pg: 156-162

In situ regulation of pulmonary macrophage TNF-alpha mRNA expression by IL2
Periodical: Chest Index Medicus:
Authors: Dubinett SM, Huang M, Dhanani S, et al ART
Yr: 1993 Vol: 103 Nbr: 2 Suppl Abs: Pg: 91S-94S

Cytokine immunotherapy of non-small cell lung cancer
Periodical: Regional Immunology Index Medicus:
Authors: Dubinett SM, Kradin RL ART
Yr: 1993 Vol: Nbr: Abs: Pg:

The effect of IL-7 expression on tumor immunogenicity
Periodical: Journal of Leukocyte Biology Index Medicus:
Authors: McBride WH, Thacker JD, Economou J, Dubinett SM, Comora S, Dougherty GJ ABS
Yr: 1992 Vol: 3 Nbr: Abs: Pg: 23

Interferon-alpha inhibits murine macrophage transforming growth factor-beta production
Periodical: American Review of Respiratory Disease Index Medicus:
Authors: Dhanani S, Huang M, Dubinett SM ABS
Yr: 1993 Vol: 147 Nbr: Abs: A758 Pg:

Corticotropin releasing factor reduces lipopolysaccharide-induced pulmonary vascular leak
Periodical: American Review of Respiratory Disease Index Medicus:
Authors: Kelly DM, Lichtenstein A, Dubinett SM ABS
Yr: 1993 Vol: 147 Nbr: Abs: A69 Pg:

Down-regulation of interleukin-2-induced transforming growth factor-beta by interleukin-7
Periodical: American Review of Respiratory Disease Index Medicus:
Authors: Huang M, Dhanani S, Mintz LE, Dubinett SM ABS
Yr: 1993 Vol: 147 Nbr: Abs: A757 Pg:

Interleukin-7 down-regulates fibrosarcoma production of transforming growth factor-beta
Periodical: Proceedings of the American Association for Cancer Research Index Medicus:
Authors: Dubinett SM, Huang M, Dhanani S, McBride WH ABS
Yr: 1993 Vol: 34 Nbr: Abs: Pg: 462

Autocrine production of interleukin-8 decreases lung cancer proliferation and augments lymphocyte-tumor adhesion
Periodical: Journal of Immunology Index Medicus:
Authors: Wang J, Huang M, Dubinett SM ABS
Yr: 1993 Vol: 150 Nbr: Abs: 89A Pg:

Cytokine gene-mediated effects of tumorigenicity and tumor immunogenicity
Periodical: Proceedings of the American Association for Cancer Research Index Medicus:
Authors: McBride WH, Chiang CS, Dubinett SM, et al ABS
Yr: 1993 Vol: 34 Nbr: Abs: Pg: 463