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Detrimental Influence of NO on Vascular/Platelet Functions

Institution: University of California, Los Angeles
Investigator(s): Louis Ignarro, Ph.D.
Award Cycle: 1992 (Cycle 1) Grant #: 1RT-0033 Award: $288,188
Subject Area: Cardiovascular Disease
Award Type: Research Project Awards
Abstracts
Publications

Role of L-arginine-nitric oxide pathway in myocardial reoxygenation injury
Periodical: American Journal of Physiology Index Medicus:
Authors: Matheis G, Sherman MP, Buckberg GD, Haybron DM, Young HH, Ignarro LJ ART
Yr: 1992 Vol: 262 Nbr: 2 Pt 2 Abs: Pg: H616-H620

Comparison of the inhibitory potencies of N-methyl-, N-nitro-, and N-amino-L-arginine on EDRF function in the rat: evidence for continuous basal EDRF release
Periodical: Index Medicus:
Authors: Vargas HM, Cuevas JM, Ignarro LJ, Chaudhuri G ART
Yr: 1991 Vol: 257 Nbr: 3 Abs: Pg: 1208-1215

Electrical field stimulation causes endothelium-dependent and nitric oxide- mediated relaxation of pulmonary artery
Periodical: American Journal of Physiology Index Medicus:
Authors: Buga GM, Ignarro LJ ART
Yr: 1992 Vol: 262 Nbr: 4 Pt 2 Abs: Pg: H973-H979

Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to noradrenergic, noncholinergic neurotransmission
Periodical: New England Journal of Medicine Index Medicus:
Authors: Rajfer J, Aronson WJ, Bush PA, Dorey FJ, Ignarro LJ ART
Yr: 1992 Vol: 326 Nbr: 2 Abs: Pg: 90-94

Comparison of nonadrenergic, noncholinergic- and nitric oxide-mediated relaxation of corpus cavernosum
Periodical: International Journal of Impotence Research Index Medicus:
Authors: Bush PA, Aronson WJ, Rajfer J, Buga GM, Ignarro LJ ART
Yr: 1992 Vol: 4 Nbr: Abs: Pg: 85-93

Nitric oxide is a potent relaxant of human and rabbit corpus cavernosum
Periodical: Journal of Urology Index Medicus:
Authors: Bush PA, Aronson WJ, Buga GM, Rajfer J, Ignarro LJ ART
Yr: 1992 Vol: 147 Nbr: 6 Abs: Pg: 1650-1655

Constitutive nitric oxide synthase from cerebellum is reversibly inhibited by nitric oxide formed from L-arginine
Periodical: Biochemistry and Biophysics Research Communications Index Medicus:
Authors: Rogers NE, Ignarro LJ ART
Yr: 1992 Vol: 189 Nbr: 1 Abs: Pg: 242-249

Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Ignarro LJ, Fukuto JM, Griscavage JM, Rogers NE, Byrns RE ART
Yr: 1993 Vol: 90 Nbr: 17 Abs: Pg: 8103-8107

Conversion of nitroxyl (HNO) to nitric oxide (NO) in biological systems: the role of physiological oxidants and relevance to the biological activity of HNO
Periodical: Biochemistry and Biophysics Research Communications Index Medicus:
Authors: Fukuto JM, Hobbs AJ, Ignarro LJ ART
Yr: 1993 Vol: 196 Nbr: 2 Abs: Pg: 707-713

Role of controlled cardiac reoxygenation in reducing nitric oxide production and cardiac oxidant damage in cyanotic infantile hearts
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Morita K, Ihnken K, Buckberg GD, Sherman MP, Young HH, Ignarro LJ ART
Yr: 1994 Vol: 93 Nbr: 6 Abs: Pg: 2658-2666

Nitric oxide inhibits neuronal nitric oxide synthase by interacting with the heme prosthetic group: role of tetrahydrobiopterin in modulating the inhibitory action of nitric oxide
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Griscavage JM, Fukuto JM, Komori Y, Ignarro LJ ART
Yr: 1994 Vol: 269 Nbr: 34 Abs: Pg: 21644-21649

Nitric oxide regulates endothelium-dependent vasodilation in the hindquarters vascular bed in vivo
Periodical: Circulation Research Index Medicus:
Authors: Cohen G, Zinner M, Chaudhuri G, Ignarro LJ ART
Yr: 1994 Vol: Nbr: Abs: Pg:

Role of L-arginine-nitric oxide pathway in myocardial reoxygenation injury
Periodical: American Journal of Physiology Index Medicus:
Authors: Matheis G, Sherman MP, Buckberg GD, Haybron DM, Young HH, Ignarro LJ ART
Yr: 1992 Vol: 262 Nbr: 2 Pt 2 Abs: Pg: H616-H620

Comparison of the inhibitory potencies of N-methyl-, N-nitro-, and N-amino-L-arginine on EDRF function in the rat: evidence for continuous basal EDRF release
Periodical: Index Medicus:
Authors: Vargas HM, Cuevas JM, Ignarro LJ, Chaudhuri G ART
Yr: 1991 Vol: 257 Nbr: 3 Abs: Pg: 1208-1215

Electrical field stimulation causes endothelium-dependent and nitric oxide- mediated relaxation of pulmonary artery
Periodical: American Journal of Physiology Index Medicus:
Authors: Buga GM, Ignarro LJ ART
Yr: 1992 Vol: 262 Nbr: 4 Pt 2 Abs: Pg: H973-H979

Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to noradrenergic, noncholinergic neurotransmission
Periodical: New England Journal of Medicine Index Medicus:
Authors: Rajfer J, Aronson WJ, Bush PA, Dorey FJ, Ignarro LJ ART
Yr: 1992 Vol: 326 Nbr: 2 Abs: Pg: 90-94

Comparison of nonadrenergic, noncholinergic- and nitric oxide-mediated relaxation of corpus cavernosum
Periodical: International Journal of Impotence Research Index Medicus:
Authors: Bush PA, Aronson WJ, Rajfer J, Buga GM, Ignarro LJ ART
Yr: 1992 Vol: 4 Nbr: Abs: Pg: 85-93

Nitric oxide is a potent relaxant of human and rabbit corpus cavernosum
Periodical: Journal of Urology Index Medicus:
Authors: Bush PA, Aronson WJ, Buga GM, Rajfer J, Ignarro LJ ART
Yr: 1992 Vol: 147 Nbr: 6 Abs: Pg: 1650-1655

Constitutive nitric oxide synthase from cerebellum is reversibly inhibited by nitric oxide formed from L-arginine
Periodical: Biochemistry and Biophysics Research Communications Index Medicus:
Authors: Rogers NE, Ignarro LJ ART
Yr: 1992 Vol: 189 Nbr: 1 Abs: Pg: 242-249

Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Ignarro LJ, Fukuto JM, Griscavage JM, Rogers NE, Byrns RE ART
Yr: 1993 Vol: 90 Nbr: 17 Abs: Pg: 8103-8107

Conversion of nitroxyl (HNO) to nitric oxide (NO) in biological systems: the role of physiological oxidants and relevance to the biological activity of HNO
Periodical: Biochemistry and Biophysics Research Communications Index Medicus:
Authors: Fukuto JM, Hobbs AJ, Ignarro LJ ART
Yr: 1993 Vol: 196 Nbr: 2 Abs: Pg: 707-713

Role of controlled cardiac reoxygenation in reducing nitric oxide production and cardiac oxidant damage in cyanotic infantile hearts
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Morita K, Ihnken K, Buckberg GD, Sherman MP, Young HH, Ignarro LJ ART
Yr: 1994 Vol: 93 Nbr: 6 Abs: Pg: 2658-2666

Nitric oxide inhibits neuronal nitric oxide synthase by interacting with the heme prosthetic group: role of tetrahydrobiopterin in modulating the inhibitory action of nitric oxide
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Griscavage JM, Fukuto JM, Komori Y, Ignarro LJ ART
Yr: 1994 Vol: 269 Nbr: 34 Abs: Pg: 21644-21649

Nitric oxide regulates endothelium-dependent vasodilation in the hindquarters vascular bed in vivo
Periodical: Circulation Research Index Medicus:
Authors: Cohen G, Zinner M, Chaudhuri G, Ignarro LJ ART
Yr: 1994 Vol: Nbr: Abs: Pg: