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An Endogenous Lectin in Airway Epithelium & Lung Cancer

Institution: University of California, San Francisco
Investigator(s): Hakon Leffler, M.D., Ph.D.
Award Cycle: 1992 (Cycle 1) Grant #: 1RT-0279 Award: $463,703
Subject Area: Pulmonary Disease
Award Type: Research Project Awards
Abstracts
Publications

Apical secretion of the lactose binding lectin L-29 in MDCK cells by a non-classical pathway
Periodical: Journal of Cell Biology Index Medicus:
Authors: Lindstedt R, Apodaca G, Barondes S, Mostov K, Leffler H ABS
Yr: 1991 Vol: 115 Nbr: Abs: Pg: 399A

Isolation and expression of a gene encoding L-14-II, a new human soluble lactose-binding lectin
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Gitt MA, Massa S, Leffler H, Barondes SH ART
Yr: 1992 Vol: 267 Nbr: 15 Abs: Pg: 10601-10606

Soluble lactose binding lectin from rat intestine with two different carbohydrate binding domains in the same peptide chain
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Oda Y, Herrman J, Gitt M, et al ART
Yr: 1993 Vol: 268 Nbr: 8 Abs: Pg: 5929-5939

L-29, an endogenous lectin, binds to glycoconjugate ligands with positive cooperativity
Periodical: Biochemistry Index Medicus:
Authors: Massa SM, Cooper DNW, Leffler H, Barondes SH ART
Yr: 1993 Vol: 32 Nbr: 1 Abs: Pg: 260-267

Two members of the S-Lac lectin gene family, LGALS1 and LGALS2, reside in close proximity of human chromosome 22g12-13
Periodical: Genomics Index Medicus:
Authors: Mehrabian M, Gott MA, Sparkes RS, Leffler H, Barondes SH, Lusis AJ ART
Yr: 1993 Vol: 15 Nbr: 2 Abs: Pg: 418-420

Apical secretion of a cytosolic protein by MDCK cells: evidence for polarized release of an endogenous lectin by a non-classical secretory pathway
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Lindstedt R, Apodaca G, Barondes S, Mostov K, Leffler H ART
Yr: 1993 Vol: 268 Nbr: 16 Abs: Pg: 11750-11757

Selected aspects of the possible interaction between animal lectins and bacterial carbohydrates
Periodical: Methods in Enzymology Index Medicus:
Authors: Mandrell RE, Apicella MA, Lindstedt R, Leffler H ART
Yr: 1993 Vol: Nbr: Abs: Pg: