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Integrin Distribution & Function in Lung Carcinoma Cells

Institution: University of California, San Francisco
Investigator(s): Robert Pytela, Ph.D.
Award Cycle: 1992 (Cycle 1) Grant #: 1RT-0338 Award: $358,128
Subject Area: Cancer
Award Type: Research Project Awards

Characterization of the integrin alphavbeta6 as a fibronectin-binding protein
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Busk M, Pytela R, Sheppard D ART
Yr: 1992 Vol: 2679 Nbr: 9 Abs: Pg: 5790-5796

Role of integrin alpha4beta7/alpha4betaP in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering
Periodical: Journal of Cell Biology Index Medicus:
Authors: Ruegg C, Postigo AA, Sikorski EE, Butcher EC, Pytela R, Erle DJ ART
Yr: 1992 Vol: 117 Nbr: 1 Abs: Pg: 179-189

Novel integrin alpha and beta subunit cDNAs identified in airway epithelial cells and lung leukocytes using the polymerase chain reaction
Periodical: American Journal of Respiratory Cell and Molecular Biology Index Medicus:
Authors: Erle DJ, Sheppard D, Breuss J, Ruegg C, Pytela R ART
Yr: 1991 Vol: 5 Nbr: 2 Abs: Pg: 170-177

Complete amino acid sequence of beta7, an integrin beta subunit identified in leukocytes
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Erle DJ, Ruegg C, Sheppard D, Pytela R ART
Yr: 1991 Vol: 266 Nbr: 17 Abs: Pg: 11009-11016

Evidence of a role for mesothelial cell derived interleukin-8 in the pathogenesis of asbestos-induced pleurisy in rabbits
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Boylan AM, Ruegg C, Kim KJ, et al ART
Yr: 1992 Vol: 89 Nbr: 4 Abs: Pg: 1257-1267

Restricted distribution of integrin beta6 messenger RNA in primate epithelial tissues
Periodical: Journal of Histochemistry and Cytochemistry Index Medicus:
Authors: Breuss JM, Gillett N, Lu L, Sheppard D, Pytela R ART
Yr: 1993 Vol: 41 Nbr: 10 Abs: Pg: 1521-1527