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Lung Cancer: p53 as a Paradigm of Tumor Suppression

Institution: University of California, Los Angeles
Investigator(s): Phillip Koeffler, M.D.
Award Cycle: 1992 (Cycle 1) Grant #: 1RT-0370 Award: $327,795
Subject Area: Cancer
Award Type: Research Project Awards

A potential transcriptional activation element in the p53 protein
Periodical: Oncogene Index Medicus:
Authors: O'Rourke RW, Miller CW, Kato GJ, et al. ART
Yr: 1990 Vol: 5 Nbr: 12 Abs: Pg: 1829-1832

p53 Mutation in Human Lung Tumors
Periodical: Cancer Research Index Medicus:
Authors: Miller CW, Simon K, Aslo A, et al ART
Yr: 1992 Vol: 52 Nbr: 7 Abs: Pg: 1695-1698

Molecular mechanisms of cancer
Periodical: Index Medicus:
Authors: Koeffler HP, McCormick F, Denny C ART
Yr: 1991 Vol: 155 Nbr: Abs: Pg: 505-514

Mutations of p53 and human papillomavirus infection occur independently in cervical carcinoma
Periodical: Cancer Index Medicus:
Authors: Paquette RL, Karmakar A, Kizaki M, Wilcynzski SP, Miller CW, Koeffler HP ART
Yr: 1993 Vol: 72 Nbr: 4 Abs: Pg: 1272-1280

Mutant p53 proteins have diverse intracellular abilities to oligomerize and activate transcription
Periodical: Oncogene Index Medicus:
Authors: Miller CW, Chumakov A, Said J, Chen DL, Aslo A, Koeffler HP ART
Yr: 1993 Vol: 8 Nbr: 7 Abs: Pg: 1815-1824