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Complement Mediated Cardiac Ischemei & Thromboxane Release

Institution: Veterans Medical Research Foundation
Investigator(s): Bruce Ito,
Award Cycle: 1992 (Cycle 1) Grant #: 1RT-0400 Award: $291,601
Subject Area: Cardiovascular Disease
Award Type: Research Project Awards
Abstracts
Publications

Platelet depletion does not prevent myocardial dysfunction and thromboxane production induced by intracoronary C5a
Periodical: FASEB Journal Index Medicus:
Authors: del Balzo U, Engler RL, Ito B ABS
Yr: 1991 Vol: 5 Nbr: 5 Abs: Pg: A1104

Myocardial mast cell degranulation is implicated in the ischemia induced by activated complement C5a
Periodical: FASEB Journal Index Medicus:
Authors: Ito BR, del Balzo U, Engler RL ABS
Yr: 1992 Vol: 6 Nbr: 4 Abs: Pg: A943

Inhibition of platelet cyclooxygenase does not reduce the thromboxane release and myocardial ischemia in response to activated complement c5a
Periodical: FASEB Journal Index Medicus:
Authors: del Balzo U, Engler RL, Juneau CF, Ito BR ABS
Yr: 1992 Vol: 6 Nbr: 4 Abs: Pg: A943

The anti CD-18 antibody IB4 protects against C5a mediated myocardial ischemia by a neutrophil-independent mechanism
Periodical: Circulation Index Medicus:
Authors: del Balzo U, Engler RL, Ito BR ABS
Yr: 1992 Vol: 86 Nbr: Abs: Pg: I79

Complement C5a-mediated myocardial ischemia and neutrophil sequestration: two independent phenomena
Periodical: American Journal of Physiology Index Medicus:
Authors: del Balzo U, Engler RL, Ito BR ART
Yr: 1993 Vol: 264 Nbr: 2 Pt 2 Abs: Pg: H336-H344

Role of cardiac mast cells in complement C5a-induced myocardial ischemia
Periodical: American Journal of Physiology Index Medicus:
Authors: Ito BR, Engler RL, del Balzo U ART
Yr: 1993 Vol: 264 Nbr: 5 Pt 2 Abs: Pg: H1346-H1354