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Smoking-Induced Mod. of Resp. Burst Oxidase of Human Phagocy

Institution: University of California, San Diego
Investigator(s): Robert Smith, M.D.
Award Cycle: 1992 (Cycle 1) Grant #: 1RT-0457 Award: $298,435
Subject Area: Pulmonary Disease
Award Type: Research Project Awards
Abstracts
Publications

Evidence that the NADPH binding subunit of the neutrophil respiratory burst oxidase is contained on a novel cytosolic subunit
Periodical: Clinical Research Index Medicus:
Authors: Smith RM, Curnutte JT ABS
Yr: 1991 Vol: 39 Nbr: Abs: Pg: 31A

Identification of the NADPH-binding subunit of the respiratory burst oxidase
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Umei T, Babior BM, Curnutte JT, Smith RM ART
Yr: 1991 Vol: 266 Nbr: 10 Abs: Pg: 6019-6022

The cytosolic components of the NADPH oxidase exist as two complexes in the unstimulated neutrophil
Periodical: Blood Index Medicus:
Authors: Heyworth PG, Tolley JO, Smith RM, et al. ABS
Yr: 1991 Vol: Nbr: Abs: Pg:

Molecular basis of chronic granulomatous disease
Periodical: Blood Index Medicus:
Authors: Smith RM, Curnette JT ART
Yr: 1991 Vol: 77 Nbr: 4 Abs: Pg: 673-686

Inducibility of human and murine mononuclear phagocyte nitric oxide synthase by lipopolysacharide and gamma-interferon
Periodical: American Review of Respiratory Disease Index Medicus:
Authors: Hite RD, Smith RM ABS
Yr: 1992 Vol: 145 Nbr: Abs: Pg: A284

N-monomethylarginine increases oxidant production in human monocytes independent of extracellular nitric oxide
Periodical: Clinical Research Index Medicus:
Authors: Hite RD, Smith RM ABS
Yr: 1992 Vol: 40 Nbr: 2 Abs: Pg: 162A

Characterization of type I NO synthase from rat cerebellum: a biopterin-flavo-protein differentially regulated by Ca2+/calmodulin
Periodical: FASEB Journal Index Medicus:
Authors: Schmidt HHW, Nakane M, Smith RM, Murad F ABS
Yr: 1992 Vol: Nbr: Abs: Pg:

Ca2+/calmodulin-depedent NO synthase type I: a bioptero-flavo-protein with Ca2+/calmodulin-independent diaphorase and reductase activities
Periodical: Biochemistry Index Medicus:
Authors: Schmidt HHW, Smith RM, Nakane M, Murad F ART
Yr: 1992 Vol: 31 Nbr: 12 Abs: Pg: 3243-3249

Translocution of neutrophil respiratory burst oxidase components from cytosol to membranes in a cell-free system
Periodical: Clinical Research Index Medicus:
Authors: Smith RM, Connor J ABS
Yr: 1992 Vol: 40 Nbr: 1 Abs: Pg: 31A

O2 production by B lymphocytes lacking the respiratory burst oxidase subunit p47phox after transfection with an expression vector containing a p47phox cDNA
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Chanock SJ, Faust LR, Barrett D, et al ART
Yr: 1992 Vol: 89 Nbr: 21 Abs: Pg: 10174-10177

Surfactant inhibits neutrophil superoxide production in response to both receptor and non-receptor mediated agonists
Periodical: American Review of Respiratory Disease Index Medicus:
Authors: Smith RM, Ahuja A, Cochrane CG, Spragg RG ABS
Yr: 1993 Vol: 147 Nbr: 4 Abs: Pg: A265

O2 production by B lymphocytes lacking the respiratory burst oxidase subunit p47phox after transfection with an expression vector containing a p47phox cDNA
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Chanock SJ, Faust LR, Barrett D, et al ART
Yr: 1992 Vol: 89 Nbr: 21 Abs: Pg: 10174-10177

Surfactant inhibits neutrophil superoxide production in response to both receptor and non-receptor mediated agonists
Periodical: American Review of Respiratory Disease Index Medicus:
Authors: Smith RM, Ahuja A, Cochrane CG, Spragg RG ABS
Yr: 1993 Vol: Nbr: Abs: A265 Pg: