Research Portfolio

Funding Opportunities

Join our Mailing List
Join our mailing list to be notified of new funding opportunities.

Your Email

To receive information about funding opportunities, events, and program updates.



Expression of a drug resistance gene in head and neck cancer

Institution: University of California, San Diego
Investigator(s): Stephen Howell, M.D.
Award Cycle: 1993 (Cycle 2) Grant #: 2RT-0142 Award: $337,086
Subject Area: Cancer
Award Type: Research Project Awards
Abstracts
Publications

Regulation of the expression of heat shock protein 60 (HSP60) mRNA in a human ovarian carcinoma cell line
Periodical: Proceedings of the American Association for Cancer Research Index Medicus:
Authors: Kimura E, Howell SB ABS
Yr: 1992 Vol: 33 Nbr: Abs: Pg: 362

Correlation of survival with mRNA expression of 60kD heat shock protein (HSP60) in ovarian cancer patients
Periodical: Proceedings of the American Society of Clinical Oncology Index Medicus:
Authors: Kimura E, Enns RE, Arboleda MJ, Slamon DJ, Howell SB ABS
Yr: 1992 Vol: 11 Nbr: Abs: Pg: 101

DNA damage and early-response genes as a tool to monitor tumor injury following chemotherapy
Periodical: Proceedings of the American Association for Cancer Research Index Medicus:
Authors: Los G, Barton RM, Nakata B, Lee LK, van Veelen LR, Howell SB ABS
Yr: 1993 Vol: 34 Nbr: Abs: Pg: 433

Quantitation of tumor platinum content in patients receiving superselective arterial infusion (s.A.I.) of high dose cisplatin (cddp) in advanced head and neck cancers: a preliminary report
Periodical: Proceedings of the American Society of Clinical Oncology Index Medicus:
Authors: Los G, Robbins TK, Barton RM, et al ABS
Yr: 1993 Vol: 12 Nbr: Abs: Pg: 284

A correlation between the expression of hsp60 mRNA and the emergence of cisplatin resistance in head and neck carcinoma cell lines
Periodical: Index Medicus:
Authors: Nakata B, Barton RM, Chung YS, Sowa M, Howell SB, Los G ABS
Yr: 1993 Vol: 52 Nbr: Abs: Pg: 642

Correlation of the survival of ovarian cancer patients with mRNA expression of the 60-kD heat-shock protein HSP-60
Periodical: Journal of Clinical Oncology Index Medicus:
Authors: Kimura E, Enns RE, Alcaraz JE, Arboleda J, Slamon DJ, Howell SB ART
Yr: 1993 Vol: 11 Nbr: 5 Abs: Pg: 891-898

Regulation of HSP60 mRNA expression in a human ovarian carcinoma cell line
Periodical: Cancer Chemotherapy and Pharmacology Index Medicus:
Authors: Kimura E, Enns RE, Thiebaut F, Howell SB ABS
Yr: 1993 Vol: 32 Nbr: 4 Abs: Pg: 279-285

Association between over-expression of hsp60 and cisplatin resistance in head and neck cancer cells
Periodical: Proceedings of the American Association for Cancer Research Index Medicus:
Authors: Nakata B, Barton R, Howell SB, Los G ABS
Yr: 1994 Vol: 35 Nbr: Abs: Pg: 466

Selective intra-arterial (i.A.) infusion of high dose cisplatin (cddp) in advanced head and neck cancer patients results in high tumor platinum (pt) concentrations and cisplatin dna adduct formation
Periodical: Proceedings of the American Society of Clinical Oncology Index Medicus:
Authors: Los G, Vicario D, Barton RM, et al ABS
Yr: 1994 Vol: 13 Nbr: Abs: Pg: 908

Platinum resistance; experimental and clinical status
Periodical: Hematology/Oncology Clinics of North America Index Medicus:
Authors: Los G, Muggia FM ART
Yr: 1994 Vol: 8 Nbr: 2 Abs: Pg: 411-429

Association between DNA damage-inducible gene expression and tumor response
Periodical: Proceedings of the American Association for Cancer Research Index Medicus:
Authors: Los G, Barton R, van Veelen L, et al ABS
Yr: 1994 Vol: 35 Nbr: Abs: Pg: 550

Induction of Gadd153 in human ovarian and human melanoma xenografs as an indicator of genotoxic injury
Periodical: Proceedings of the American Society of Clinical Oncology Index Medicus:
Authors: Jones JA, Gately DP, Albright KD, Christen RD, McClay EF, Howell SB ABS
Yr: 1993 Vol: 12 Nbr: Abs: Pg: 111

Induction of Gadd153 in vitro and in vivo by cisplatin
Periodical: Proceedings of the American Association for Cancer Research Index Medicus:
Authors: Gately DP, Jones JA, Howell SB ABS
Yr: 1993 Vol: 34 Nbr: Abs: Pg: 503

Synergistic interaction between cisplatin and tamoxifen and the delay of cisplatin resistance in head and neck carcinoma cell lines
Periodical: Cancer Chemotherapy and Pharmacology Index Medicus:
Authors: Nakata B, Albright KD, Barton RM, Howell SB, Los G ART
Yr: 1995 Vol: 35 Nbr: 6 Abs: Pg: 511-518

Cisplatin resistance and overexpression of heat shock proteins
Periodical: Nippon Geka Gakka Zasshi - Journal of Japan Surgical Society Index Medicus:
Authors: Nakata B, Chung YS, Nitta A, et al ABS
Yr: 1995 Vol: 96 Nbr: Abs: Pg: 269

Selective intra-arterial infusion of high dose cisplatin in advanced head and neck cancer patients results in high tumor platinum concentrations and cisplatin-DNA adduct formation
Periodical: Cancer Chemotherapy and Pharmacology Index Medicus:
Authors: Los G, Barton R, Heath DD, et al ART
Yr: 1995 Vol: Nbr: Abs: Pg:

Association between hsp60 mRNA levels and cisplatin resistance in human head and neck cancer cell lines
Periodical: International Journal of Oncology Index Medicus:
Authors: Nakata B, Barton RM, Robbins RK, Howell SB, Los G ART
Yr: 1994 Vol: 5 Nbr: 6 Abs: Pg: 1425-1432

Molecular markers of tumor response in head and neck carcinoma
Periodical: Head and Neck Index Medicus:
Authors: Los G, Barton R, Vicario D, Weisman R, Robbins KT, Howell SB ABS
Yr: 1994 Vol: 16 Nbr: Abs: Pg: 509