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Diagnosis and Treatment of MTAse-Deficient Lung Cancers

Institution: University of California, San Diego
Investigator(s): Tsutomu Nobori, M.D.
Award Cycle: 1994 (Cycle 3) Grant #: 3RT-0075 Award: $370,631
Subject Area: Cancer
Award Type: Research Project Awards
Abstracts
Publications

Methylthioadenosine phosphorylase deficiency in human non-small cell lung cancres
Periodical: Cancer Research Index Medicus:
Authors: Nobori T, Szinai I, Amox D, et al ART
Yr: 1993 Vol: 53 Nbr: 5 Abs: Pg: 1098-1101

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
Periodical: Nature Index Medicus:
Authors: Nobori T, Miura K, Wu D, Lois A, Takabayashi K, Carson DA ART
Yr: 1994 Vol: 368 Nbr: 6473 Abs: Pg: 753-756

Distinct deletions of chromosome 9p associated with melanoma versus glioma, lung cancer, and leukemia
Periodical: Cancer Research Index Medicus:
Authors: Coleman A, Fountain JW, Nobori T, et al ART
Yr: 1994 Vol: 54 Nbr: 2 Abs: Pg: 344-348

Homozygous loss of the interferon genes defines the critical region on 9p that is deleted in lung cancers
Periodical: Cancer Research Index Medicus:
Authors: Olopade OI, Buchhagen DL, Malik K, et al ART
Yr: 1993 Vol: 53 Nbr: 10 Suppl Abs: Pg: 2410-2415

Deletion mapping of chromosome 9p in solid tumor cell lines by the polymerase chain reaction-based method
Periodical: Proceedings of the American Association for Cancer Research Index Medicus:
Authors: Miura K, Orvis L, Wu D, Carson DA, Nobori T ABS
Yr: 1992 Vol: 35 Nbr: Abs: Pg: 534

Higher frequency of alterations in the p16/CDKN2 gene in squamous cells carcinoma cell lines than in primary tumors of the head and neck
Periodical: Cancer Research Index Medicus:
Authors: Zhang S-Y, Klein-Szanto AJP, Sauter ER, et al ART
Yr: 1994 Vol: 54 Nbr: 19 Abs: Pg: 5050-5053

Dinucleotide repeat polymorphism adjacent to CDKN2
Periodical: Human Molecular Genetics Index Medicus:
Authors: Herbst RA, Nobori T, Cavenee WK, Carson DA, Arden KC ART
Yr: 1994 Vol: 3 Nbr: 12 Abs: Pg: 2265

p16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma
Periodical: Cancer Research Index Medicus:
Authors: Cheng IQ, Jhanwar SC, Klein WM, et al ART
Yr: 1994 Vol: 54 Nbr: 21 Abs: Pg: 5547-5551

Homozygous deletions of p16/MTS1 gene are frequent but mutations are infrequent in childhood T-cell acute lymphoblastic leukemias
Periodical: Blood Index Medicus:
Authors: Ohnishi H, Kawamura M, Ida K, et al ART
Yr: 1995 Vol: 86 Nbr: 4 Abs: Pg: 1269-1275

Potential role of the tumor suppressor p16 in cell cycle arrest during terminal differentiation of neuronal cells
Periodical: Cancer Research Index Medicus:
Authors: Lois AF, Cooper LT, Yu G, Nobori T, Carson DA ART
Yr: 1995 Vol: 55 Nbr: 18 Abs: Pg: 4010-4013