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Diagnosis and Treatment of MTAse-Deficient Lung Cancers

Institution:	University of California, San Diego
Investigator(s):	Tsutomu Nobori, M.D.
Award Cycle:	1994 (Cycle 3)	Grant #: 3RT-0075	Award: $370,631
Subject Area:	Cancer
Award Type:	Research Project Awards

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Methylthioadenosine phosphorylase deficiency in human non-small cell lung cancres
Periodical: Cancer Research			Index Medicus:
Authors: Nobori T, Szinai I, Amox D, et al				ART
Yr: 1993	Vol: 53	Nbr: 5	Abs:	Pg: 1098-1101

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Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
Periodical: Nature			Index Medicus:
Authors: Nobori T, Miura K, Wu D, Lois A, Takabayashi K, Carson DA				ART
Yr: 1994	Vol: 368	Nbr: 6473	Abs:	Pg: 753-756

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Distinct deletions of chromosome 9p associated with melanoma versus glioma, lung cancer, and leukemia
Periodical: Cancer Research			Index Medicus:
Authors: Coleman A, Fountain JW, Nobori T, et al				ART
Yr: 1994	Vol: 54	Nbr: 2	Abs:	Pg: 344-348

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Homozygous loss of the interferon genes defines the critical region on 9p that is deleted in lung cancers
Periodical: Cancer Research			Index Medicus:
Authors: Olopade OI, Buchhagen DL, Malik K, et al				ART
Yr: 1993	Vol: 53	Nbr: 10 Suppl	Abs:	Pg: 2410-2415

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Deletion mapping of chromosome 9p in solid tumor cell lines by the polymerase chain reaction-based method
Periodical: Proceedings of the American Association for Cancer Research			Index Medicus:
Authors: Miura K, Orvis L, Wu D, Carson DA, Nobori T				ABS
Yr: 1992	Vol: 35	Nbr:	Abs:	Pg: 534

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Higher frequency of alterations in the p16/CDKN2 gene in squamous cells carcinoma cell lines than in primary tumors of the head and neck
Periodical: Cancer Research			Index Medicus:
Authors: Zhang S-Y, Klein-Szanto AJP, Sauter ER, et al				ART
Yr: 1994	Vol: 54	Nbr: 19	Abs:	Pg: 5050-5053

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Dinucleotide repeat polymorphism adjacent to CDKN2
Periodical: Human Molecular Genetics			Index Medicus:
Authors: Herbst RA, Nobori T, Cavenee WK, Carson DA, Arden KC				ART
Yr: 1994	Vol: 3	Nbr: 12	Abs:	Pg: 2265

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p16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma
Periodical: Cancer Research			Index Medicus:
Authors: Cheng IQ, Jhanwar SC, Klein WM, et al				ART
Yr: 1994	Vol: 54	Nbr: 21	Abs:	Pg: 5547-5551

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Homozygous deletions of p16/MTS1 gene are frequent but mutations are infrequent in childhood T-cell acute lymphoblastic leukemias
Periodical: Blood			Index Medicus:
Authors: Ohnishi H, Kawamura M, Ida K, et al				ART
Yr: 1995	Vol: 86	Nbr: 4	Abs:	Pg: 1269-1275

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Potential role of the tumor suppressor p16 in cell cycle arrest during terminal differentiation of neuronal cells
Periodical: Cancer Research			Index Medicus:
Authors: Lois AF, Cooper LT, Yu G, Nobori T, Carson DA				ART
Yr: 1995	Vol: 55	Nbr: 18	Abs:	Pg: 4010-4013

---

Methylthioadenosine phosphorylase deficiency in human non-small cell lung cancres
Periodical: Cancer Research			Index Medicus:
Authors: Nobori T, Szinai I, Amox D, et al				ART
Yr: 1993	Vol: 53	Nbr: 5	Abs:	Pg: 1098-1101

---

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
Periodical: Nature			Index Medicus:
Authors: Nobori T, Miura K, Wu D, Lois A, Takabayashi K, Carson DA				ART
Yr: 1994	Vol: 368	Nbr: 6473	Abs:	Pg: 753-756

---

Distinct deletions of chromosome 9p associated with melanoma versus glioma, lung cancer, and leukemia
Periodical: Cancer Research			Index Medicus:
Authors: Coleman A, Fountain JW, Nobori T, et al				ART
Yr: 1994	Vol: 54	Nbr: 2	Abs:	Pg: 344-348

---

Homozygous loss of the interferon genes defines the critical region on 9p that is deleted in lung cancers
Periodical: Cancer Research			Index Medicus:
Authors: Olopade OI, Buchhagen DL, Malik K, et al				ART
Yr: 1993	Vol: 53	Nbr: 10 Suppl	Abs:	Pg: 2410-2415

---

Deletion mapping of chromosome 9p in solid tumor cell lines by the polymerase chain reaction-based method
Periodical: Proceedings of the American Association for Cancer Research			Index Medicus:
Authors: Miura K, Orvis L, Wu D, Carson DA, Nobori T				ABS
Yr: 1992	Vol: 35	Nbr:	Abs:	Pg: 534

---

Higher frequency of alterations in the p16/CDKN2 gene in squamous cells carcinoma cell lines than in primary tumors of the head and neck
Periodical: Cancer Research			Index Medicus:
Authors: Zhang S-Y, Klein-Szanto AJP, Sauter ER, et al				ART
Yr: 1994	Vol: 54	Nbr: 19	Abs:	Pg: 5050-5053

---

Dinucleotide repeat polymorphism adjacent to CDKN2
Periodical: Human Molecular Genetics			Index Medicus:
Authors: Herbst RA, Nobori T, Cavenee WK, Carson DA, Arden KC				ART
Yr: 1994	Vol: 3	Nbr: 12	Abs:	Pg: 2265

---

p16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma
Periodical: Cancer Research			Index Medicus:
Authors: Cheng IQ, Jhanwar SC, Klein WM, et al				ART
Yr: 1994	Vol: 54	Nbr: 21	Abs:	Pg: 5547-5551

---

Homozygous deletions of p16/MTS1 gene are frequent but mutations are infrequent in childhood T-cell acute lymphoblastic leukemias
Periodical: Blood			Index Medicus:
Authors: Ohnishi H, Kawamura M, Ida K, et al				ART
Yr: 1995	Vol: 86	Nbr: 4	Abs:	Pg: 1269-1275

---

Potential role of the tumor suppressor p16 in cell cycle arrest during terminal differentiation of neuronal cells
Periodical: Cancer Research			Index Medicus:
Authors: Lois AF, Cooper LT, Yu G, Nobori T, Carson DA				ART
Yr: 1995	Vol: 55	Nbr: 18	Abs:	Pg: 4010-4013

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