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Pathogenesis of Smoke-Induced Injury in Airway Epithelium

Institution: University of California, Davis
Investigator(s): Reen Wu, Ph.D.
Award Cycle: 1994 (Cycle 3) Grant #: 3RT-0409 Award: $431,266
Subject Area: Pulmonary Disease
Award Type: Research Project Awards
Abstracts
Publications

Transcriptional regulation of human TGF-a in airway epithelium: inhibition of TGF-a expression by TGF-b1
Periodical: American Review of Respiratory Disease Index Medicus:
Authors: Miller LA, Wu R ABS
Yr: 1993 Vol: 147 Nbr: 4 Abs: Pg: A275

Inhibition of epidermal growth factor-like growth factor secretion in tracheobronchial epithelial cells
Periodical: Cancer Research Index Medicus:
Authors: Miller L, Cheng LZ, Wu R ART
Yr: 1993 Vol: 53 Nbr: 11 Abs: Pg: 2527-2533

Expression of a squamous cell marker, the spr1 gene is posttranscriptionally down-regulated by retinol in airway epithelium
Periodical: Journal of Cellular Physiology Index Medicus:
Authors: An G, Tesfaigzi J, Carlson DM, Wu R ART
Yr: 1993 Vol: 157 Nbr: 3 Abs: Pg: 562-568

Isolation and characterization of the human spr1 gene and its regulation of expression by phorbol ester and cyclic AMP
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: An G, Tesfaigzi J, Chuu YJ, Wu R ART
Yr: 1993 Vol: 268 Nbr: 15 Abs: Pg: 10977-10982

Control of keratin gene expression by vitamin A in tracheobronchial epithelial cells
Periodical: American Journal of Respiratory Cell and Molecular Biology Index Medicus:
Authors: Huang TH, Ann DK, Zhang YJ, Chang AT, Crabb JW, Wu R ART
Yr: 1994 Vol: 10 Nbr: 2 Abs: Pg: 192-201

A PCR differential screening method for rapid isolation of clones from a cDNA library
Periodical: Biotechniques Index Medicus:
Authors: Luo G, An G, Wu R ART
Yr: 1994 Vol: 16 Nbr: 4 Abs: Pg: 672-675

Expression of MUC-2 gene is down-regulated by vitamin A at the transcriptional level in vitro in tracheobronchial epithelial cells
Periodical: American Journal of Respiratory Cell and Molecular Biology Index Medicus:
Authors: An G, Lui G, Wu R ART
Yr: 1994 Vol: 10 Nbr: 5 Abs: Pg: 546-551

In vitro exposure of tracheobronchial epithelial cells and of tracheal explants to ozone
Periodical: Toxicology Index Medicus:
Authors: Tarkington BK, Wu R, Sun WM, Nikula J, Wilson DW, Last J ART
Yr: 1994 Vol: 88 Nbr: 1-3 Abs: Pg: 51-68

Coordinated expression of 45kd protein synthesis and ozone toxicity in human bronchial epithelial cell line
Periodical: American Journal of Respiratory Cell and Molecular Biology Index Medicus:
Authors: Sun WM, Wu R, Last J ART
Yr: 1994 Vol: 10 Nbr: 6 Abs: Pg: 673-682

Coordinated expression of a 45 kilodalton protein and environmental tobacco smoke (ETS0 toxicity in a human bronchial epithelial cell line
Periodical: FASEB Journal Index Medicus:
Authors: Sun WM, Wu R, Last JA ABS
Yr: 1994 Vol: 8 Nbr: Abs: Pg: A122

Transcriptional regulation of a squamous cell differentiation marker, the spr1 gene, by phorbol ester TPA in conducting airway epithelium
Periodical: FASEB Journal Index Medicus:
Authors: Chuu YJ, Reddy S, An G, Ann DK, Wu R ABS
Yr: 1994 Vol: 8 Nbr: Abs: Pg: A124

Regulation of transforming growth factor-beta 1 gene in airway cells by vitamin A
Periodical: American Journal of Respiratory and Critical Care Medicine Index Medicus:
Authors: Robinson CB, Young R, Wu R ABS
Yr: 1994 Vol: 149 Nbr: Abs: Pg: A722

Transcriptional activation of a squamous cell differentiation marker, spr1 gene, by cigarette smoke in conducting airway epithelium
Periodical: American Journal of Respiratory and Critical Care Medicine Index Medicus:
Authors: An G, Luo G, Lao P, Shea J, Chuu YJ, Wu R ABS
Yr: 1994 Vol: 149 Nbr: Abs: Pg: A446

Effects of exposure to environmental tobacco smoke on a human tracheobronchial epithelial cell line
Periodical: Toxicology Index Medicus:
Authors: Sun WM, Wu R, Last JA ART
Yr: 1995 Vol: 100 Nbr: Abs: Pg: 163-174

Glutathione S-transferase in tracheobronchial epithelium: differential expression and regulation by vitamin A and collagen substratum
Periodical: American Journal of Physiology Index Medicus:
Authors: Reddy SP-M, Tu D, Wu R ART
Yr: 1995 Vol: 269 Nbr: Abs: Pg: 473-481

Two nuclear proteins in tracheal epithelial cells are recognized by antibodies specific to a squamous differentiation marker, spr1
Periodical: Journal of Cellular Physiology Index Medicus:
Authors: Tesfaigzi J, An G, Wu R, Carlson DM ART
Yr: 1995 Vol: 164 Nbr: 3 Abs: Pg: 571-578

Cellular expression of transforming growth factor-a and its mRNA in the developing rabbit lung
Periodical: American Journal of Respiratory Cell and Molecular Biology Index Medicus:
Authors: Edward LA, Voit MM, Miller MA, Wu R, Plopper CG ART
Yr: 1995 Vol: Nbr: Abs: Pg:

Down regulation of TGF-a gene expression in conducting airway epithelium
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Miller LA, Zhao YH, Wu R ART
Yr: 1996 Vol: 97 Nbr: Abs: Pg: 1429-1435

Isolation and characterization of nucleolin gene expresion in airway epithelium by a palindromic primer-based mRNA differential display method
Periodical: American Journal of Respiratory Cell and Molecular Biology Index Medicus:
Authors: Reddy SPM, An G, Di YP, Zhao YH, Wu R ART
Yr: 1996 Vol: Nbr: Abs: Pg:

Expression of human squamous cell differentiation marker, sprl, is dependent on jun and tre motifs
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Reddy SPM, Chuu YJ, Lao PN, Donn J, Ann DK, Wu R ART
Yr: 1995 Vol: 270 Nbr: Abs: Pg: 26451-26459

DNA damage in human respiratory tract epithelial cells: damage by gas phase cigarette smoke apparently involves attack by reactive nitrogen species in addition to oxygen radicals
Periodical: FEBS Journal Index Medicus:
Authors: Spencer JPE, Jenner A, Chmiel K, Aruoma OI, Cross CE, Wu R, Halliwell B ART
Yr: 1995 Vol: 375 Nbr: Abs: Pg: 179-182

DNA strand breakage and base modification induced by hydrogen peroxide treatment of human respiratory tract epithelial cells
Periodical: FEBS Journal Index Medicus:
Authors: Spencer JPE, Jenner A, Chmiel K, Aruoma OI, Cross CE, Wu R, Halliwell B ART
Yr: 1995 Vol: 374 Nbr: Abs: Pg: 233-236