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Vitronectin in Cardiovascular Disease

Institution:	Scripps Research Institute
Investigator(s):	Dietmar Seiffert, M.D.
Award Cycle:	1995 (Cycle 4)	Grant #: 4KT-0192	Award: $352,644
Subject Area:	Cardiovascular Disease
Award Type:	New Investigator Awards

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Cytokine regulation of the murine vitronectin gene: identification of regulatory sequences for interleukin 6
Periodical: Fibrinolysis			Index Medicus:
Authors: Seiffert D, Curriden SA, Binder BR, Loskutoff DJ				ABS
Yr: 1994	Vol:	Nbr:	Abs:	Pg:

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Vitronectin gene expression in vivo: evidence for extrahepatic synthesis and acute phase regulation
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Seiffert D, Crain K, Wagner NV, Loskutoff DJ				ART
Yr: 1994	Vol: 269	Nbr: 31	Abs:	Pg: 19836-19842

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Distribution of vitronectin mRNA during murine development
Periodical: Developmental Dynamics			Index Medicus:
Authors: Seiffert D, Iruela-Arispe ML, Sage EH, Loskutoff DJ				ART
Yr: 1995	Vol: 203	Nbr: 1	Abs:	Pg: 71-79

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Expression of fibrinolytic genes in atherosclerotic abdominal aortic aneurysm wall: a possible mechnism for aneurysm expansion
Periodical: Journal of Clinical Investigation			Index Medicus:
Authors: Schneiderman J, Bordin GM, Engelberg I, et al				ART
Yr: 1995	Vol: 96	Nbr: 1	Abs:	Pg: 639-645

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IL-6 stimulates hepatocyte vitronectin gene expression in vivo
Periodical: Journal of Immunology			Index Medicus:
Authors: Seiffert D, Geisterfer M, Gauldie J, Young E, Hirsh J, Podor T				ART
Yr: 1995	Vol: 155	Nbr: 6	Abs:	Pg: 3180-3185

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Detection of vitronectin in mineralized bone matrix
Periodical: Journal of Histochemistry and Cytochemistry			Index Medicus:
Authors: Seiffert D				ART
Yr: 1996	Vol: 44	Nbr: 3	Abs:	Pg: 275-280

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Evidence that extrahepatic cells express vitronectin mRNA at rates approaching those of hepatocytes
Periodical: Histochemistry and Cell Biology			Index Medicus:
Authors: Seiffert D, Bordin GM, Loskutoff DJ				ART
Yr: 1996	Vol: 105	Nbr: 3	Abs:	Pg: 195-201

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Differential regulation of vitronectin in mice and humans in vitro
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Seiffert D, Curriden s, Jenne D, Binder BR, Loskutoff DJ				ART
Yr: 1996	Vol: 271	Nbr: 10	Abs:	Pg: 5474-5480

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Hydrolysis of platelet vitronectin by calpain
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Seiffert D				ART
Yr: 1996	Vol: 271	Nbr: 19	Abs:	Pg: 11170-11176

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Two functionally distinct pools of vitronectin (Vn) in the blood circulation: identification of a heparin-binding competent population of Vn within platelet alpha-granules
Periodical: Blood			Index Medicus:
Authors: Seiffert D, Schleef RR				ART
Yr: 1996	Vol:	Nbr:	Abs:	Pg:

---

Cytokine regulation of the murine vitronectin gene: identification of regulatory sequences for interleukin 6
Periodical: Fibrinolysis			Index Medicus:
Authors: Seiffert D, Curriden SA, Binder BR, Loskutoff DJ				ABS
Yr: 1994	Vol:	Nbr:	Abs:	Pg:

---

Vitronectin gene expression in vivo: evidence for extrahepatic synthesis and acute phase regulation
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Seiffert D, Crain K, Wagner NV, Loskutoff DJ				ART
Yr: 1994	Vol: 269	Nbr: 31	Abs:	Pg: 19836-19842

---

Distribution of vitronectin mRNA during murine development
Periodical: Developmental Dynamics			Index Medicus:
Authors: Seiffert D, Iruela-Arispe ML, Sage EH, Loskutoff DJ				ART
Yr: 1995	Vol: 203	Nbr: 1	Abs:	Pg: 71-79

---

Expression of fibrinolytic genes in atherosclerotic abdominal aortic aneurysm wall: a possible mechnism for aneurysm expansion
Periodical: Journal of Clinical Investigation			Index Medicus:
Authors: Schneiderman J, Bordin GM, Engelberg I, et al				ART
Yr: 1995	Vol: 96	Nbr: 1	Abs:	Pg: 639-645

---

IL-6 stimulates hepatocyte vitronectin gene expression in vivo
Periodical: Journal of Immunology			Index Medicus:
Authors: Seiffert D, Geisterfer M, Gauldie J, Young E, Hirsh J, Podor T				ART
Yr: 1995	Vol: 155	Nbr: 6	Abs:	Pg: 3180-3185

---

Detection of vitronectin in mineralized bone matrix
Periodical: Journal of Histochemistry and Cytochemistry			Index Medicus:
Authors: Seiffert D				ART
Yr: 1996	Vol: 44	Nbr: 3	Abs:	Pg: 275-280

---

Evidence that extrahepatic cells express vitronectin mRNA at rates approaching those of hepatocytes
Periodical: Histochemistry and Cell Biology			Index Medicus:
Authors: Seiffert D, Bordin GM, Loskutoff DJ				ART
Yr: 1996	Vol: 105	Nbr: 3	Abs:	Pg: 195-201

---

Differential regulation of vitronectin in mice and humans in vitro
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Seiffert D, Curriden s, Jenne D, Binder BR, Loskutoff DJ				ART
Yr: 1996	Vol: 271	Nbr: 10	Abs:	Pg: 5474-5480

---

Hydrolysis of platelet vitronectin by calpain
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Seiffert D				ART
Yr: 1996	Vol: 271	Nbr: 19	Abs:	Pg: 11170-11176

---

Two functionally distinct pools of vitronectin (Vn) in the blood circulation: identification of a heparin-binding competent population of Vn within platelet alpha-granules
Periodical: Blood			Index Medicus:
Authors: Seiffert D, Schleef RR				ART
Yr: 1996	Vol:	Nbr:	Abs:	Pg:

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