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Cellular Defects in Lung caused by Tobacco Smoke

Institution: University of California, San Francisco
Investigator(s): Alan Verkman, M.D., Ph.D.
Award Cycle: 1995 (Cycle 4) Grant #: 4RT-0072 Award: $319,013
Subject Area: Pulmonary Disease
Award Type: Research Project Awards
Abstracts
Publications
Functional CFTR in endosomal compartment of CFTR-expressing fibroblasts and T84 cells
Periodical: American Journal of Physiology Index Medicus:
Authors: Biwersi J, Verkman AS ART
Yr: 1994 Vol: 266 Nbr: 1 Pt 1 Abs: Pg: C149-C156
Direct measurement of trans-Golgi pH in living cells and regulation by second messengers
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Seksek O, Biwersi J, Verkman AS ART
Yr: 1995 Vol: 270 Nbr: 10 Abs: Pg: 4967-4970
Ratio imaging of endosome fusion in BHK fibroblasts based on a novel fluorimetric avidin-biotin binding assay
Periodical: Biophysical Journal Index Medicus:
Authors: Emans N, Biwersi J, Verkman AS ART
Yr: 1995 Vol: 69 Nbr: 2 Abs: Pg: 716-728
Ratio imaging measurement of trans-Golgi pH in living cells microinjected with liposome-entrapped fluorophores
Periodical: Biophysical Journal Index Medicus:
Authors: Seksek O, Biwersi J, Verkman AS ABS
Yr: 1995 Vol: 68 Nbr: Abs: Pg: A291
Real-time measurement of cell-free endosome fusion by a novel fluorescence method: kinetic analysis and regulation by second messengers
Periodical: Biophysics Journal Index Medicus:
Authors: Emans N, Verkman AS ART
Yr: 1996 Vol: 71 Nbr: Abs: Pg: 487-494
Evidence against defective trans-Golgi acidification in cystic fibrosis
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Seksek O, Biwersi J, Verkman AS ART
Yr: 1996 Vol: 271 Nbr: Abs: Pg: 15542-15548
Transalveolar osmotic and diffusional water permeability in intact mouse lung measured by a novel surface fluorescence method
Periodical: Journal of General Physiology Index Medicus:
Authors: Carter EP, Matthay MA, Farinas J, Verkman AS ART
Yr: 1996 Vol: 108 Nbr: Abs: Pg: 133-142
Cystic fibrosis transmembrane conductance regulator activation increases indosome fusion in vivo
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Biwersi J, Emans N, Verkman AS ART
Yr: 1996 Vol: 93 Nbr: Abs: Pg: 12484-12489
Developmental changes in alveolar water permeability in perinatal rabbit lung
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Carter E, Umenishi F, Matthay MA, Verkman AS ART
Yr: 0 Vol: Nbr: Abs: Pg:
High microvascular endothelial water permeability in mouse lung measured by a pleural surface fluorescence method
Periodical: Biophysical Journal Index Medicus:
Authors: Carter EP, Olveczky BP, Matthay MA, Verkman AS ART
Yr: 1998 Vol: 74 Nbr: Abs: Pg: 2121-2128
Green fluorescent protein as a non-invasive intracellular pH indicator
Periodical: Biophysical Journal Index Medicus:
Authors: Kneen M, Farinas J, Li Y, Verkman AS ART
Yr: 1998 Vol: 74 Nbr: Abs: Pg: 1591-1600
Highly water-permeable type I alveolar epithelial cells confer high water permeability between airs[ace and vasculature in rat lung
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Dobbs L, Gonzalez R, Matthay MA, Carter EP, Allen L, Verkman AS ART
Yr: 1998 Vol: 95 Nbr: Abs: Pg: 2991-2996
Role of aquaporin water channels in lung fluid transport: phenotype analysis of aquaporin 1 and 4 knockout mice
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Bai C, Matthay MA, Ma T, Verkman AS ART
Yr: 1999 Vol: Nbr: Abs: Pg:
Functional CFTR in endosomal compartment of CFTR-expressing fibroblasts and T84 cells
Periodical: American Journal of Physiology Index Medicus:
Authors: Biwersi J, Verkman AS ART
Yr: 1994 Vol: 266 Nbr: 1 Pt 1 Abs: Pg: C149-C156
Direct measurement of trans-Golgi pH in living cells and regulation by second messengers
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Seksek O, Biwersi J, Verkman AS ART
Yr: 1995 Vol: 270 Nbr: 10 Abs: Pg: 4967-4970
Ratio imaging of endosome fusion in BHK fibroblasts based on a novel fluorimetric avidin-biotin binding assay
Periodical: Biophysical Journal Index Medicus:
Authors: Emans N, Biwersi J, Verkman AS ART
Yr: 1995 Vol: 69 Nbr: 2 Abs: Pg: 716-728
Ratio imaging measurement of trans-Golgi pH in living cells microinjected with liposome-entrapped fluorophores
Periodical: Biophysical Journal Index Medicus:
Authors: Seksek O, Biwersi J, Verkman AS ABS
Yr: 1995 Vol: 68 Nbr: Abs: Pg: A291
Real-time measurement of cell-free endosome fusion by a novel fluorescence method: kinetic analysis and regulation by second messengers
Periodical: Biophysics Journal Index Medicus:
Authors: Emans N, Verkman AS ART
Yr: 1996 Vol: 71 Nbr: Abs: Pg: 487-494
Evidence against defective trans-Golgi acidification in cystic fibrosis
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Seksek O, Biwersi J, Verkman AS ART
Yr: 1996 Vol: 271 Nbr: Abs: Pg: 15542-15548
Transalveolar osmotic and diffusional water permeability in intact mouse lung measured by a novel surface fluorescence method
Periodical: Journal of General Physiology Index Medicus:
Authors: Carter EP, Matthay MA, Farinas J, Verkman AS ART
Yr: 1996 Vol: 108 Nbr: Abs: Pg: 133-142
Cystic fibrosis transmembrane conductance regulator activation increases indosome fusion in vivo
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Biwersi J, Emans N, Verkman AS ART
Yr: 1996 Vol: 93 Nbr: Abs: Pg: 12484-12489
Developmental changes in alveolar water permeability in perinatal rabbit lung
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Carter E, Umenishi F, Matthay MA, Verkman AS ART
Yr: 0 Vol: Nbr: Abs: Pg:
High microvascular endothelial water permeability in mouse lung measured by a pleural surface fluorescence method
Periodical: Biophysical Journal Index Medicus:
Authors: Carter EP, Olveczky BP, Matthay MA, Verkman AS ART
Yr: 1998 Vol: 74 Nbr: Abs: Pg: 2121-2128
Green fluorescent protein as a non-invasive intracellular pH indicator
Periodical: Biophysical Journal Index Medicus:
Authors: Kneen M, Farinas J, Li Y, Verkman AS ART
Yr: 1998 Vol: 74 Nbr: Abs: Pg: 1591-1600
Highly water-permeable type I alveolar epithelial cells confer high water permeability between airs[ace and vasculature in rat lung
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Dobbs L, Gonzalez R, Matthay MA, Carter EP, Allen L, Verkman AS ART
Yr: 1998 Vol: 95 Nbr: Abs: Pg: 2991-2996
Role of aquaporin water channels in lung fluid transport: phenotype analysis of aquaporin 1 and 4 knockout mice
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Bai C, Matthay MA, Ma T, Verkman AS ART
Yr: 1999 Vol: Nbr: Abs: Pg: