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The Dopamine D2 Receptor in Nicotine Addiction

Institution: City of Hope National Medical Center
Investigator(s): David Comings, M.D.
Award Cycle: 1995 (Cycle 4) Grant #: 4RT-0110 Award: $304,790
Subject Area: General Biomedical Science
Award Type: Research Project Awards
Abstracts
Publications

Dopamine D2 receptor gene variants: association and linkage studies in impulsive-addictive-compulsive behaviors
Periodical: Pharmacogenetics Index Medicus:
Authors: Blum K, Sheridan PJ, Wood RC, Braverman ER, Chen TJH, Comings DE ART
Yr: 1995 Vol: 5 Nbr: 3 Abs: Pg: 121-141

The Dopamine D2 receptor (DRD2) gene: a genetic risk factor in smoking
Periodical: Pharmacogenetics Index Medicus:
Authors: Comings DE, Ferry L, Bradshaw-Robinson S, et al ART
Yr: 1996 Vol: 6 Nbr: 1 Abs: Pg: 73-79

Reward deficiency syndrome
Periodical: American Scientist Index Medicus:
Authors: Blum K, Cull JG, Braverman ER, Commings DE ART
Yr: 1996 Vol: 84 Nbr: 2 Abs: Pg: 132-145

Sequence of human tryptophan 2,3-dioxygenase (TDO2): presence of a glucocorticoid response-like element composed of a GTT repeat and an intronic CCCCT repeat
Periodical: Genomics Index Medicus:
Authors: Comings DE, Muhleman D, Dieta G, Sherman M, Forest GL ART
Yr: 1995 Vol: 29 Nbr: 2 Abs: Pg: 390-396

Tourette syndrome: a hereditary neuropsyhciatric spectrum disorder
Periodical: Annals of Clinical Psychiatry Index Medicus:
Authors: Comings DE ART
Yr: 1994 Vol: 6 Nbr: 4 Abs: Pg: 235-245

A study of the dopamine D2 receptor gene in pathological gambling
Periodical: Pharmacogenetics Index Medicus:
Authors: Comings DE, Rosenthal RJ, Lesieur HR, et al ART
Yr: 1996 Vol: 6 Nbr: Abs: Pg: 223-234

Polygenic inheritance of Tourette syndrome, stuttering, attention deficit hyperactivity, conduct, and oppositional defiant disorder
Periodical: American Journal of Medical Genetics Index Medicus:
Authors: Comings DE, Wu S, Chiu C, et al ART
Yr: 1996 Vol: 67 Nbr: 3 Abs: Pg: 264-288

Exon and intron variants in the human trypophan 2,2-dioxygenase gene: potential association with Tourette syndrome, substance abuse and other disorders
Periodical: Pharmacogenetics Index Medicus:
Authors: Comings DE ART
Yr: 1996 Vol: Nbr: 6 Abs: Pg:

The molecular genetics of pathological gambing
Periodical: CNS Spectrums Index Medicus:
Authors: Coming, DE ART
Yr: 1998 Vol: Nbr: Abs: Pg:

Exon & intron variants in the human tryptophan 2.3-dioxygenase gene: potential association with Tourette Syndrome, substance abuse & other disorders
Periodical: Pharmacogenetics Index Medicus:
Authors: Comings DE, et al ART
Yr: 1996 Vol: Nbr: Abs: Pg: 6,307-6318

Correlation of length of VNTR alleles at the X-linked MAOA gene & phenotypic effect in Tourette Syndrome & drug abuse
Periodical: Molecular Psychiatry Index Medicus:
Authors: Gade R, Muhleman D, Blake H, MacMurray J, et al ART
Yr: 1997 Vol: Nbr: Abs: Pg:

Studies of the potential role of the dopamine D1 receptor gene in addictive behaviors
Periodical: Molecular Psychiatry Index Medicus:
Authors: Comings DE, et al ART
Yr: 1997 Vol: 2 Nbr: Abs: Pg: 44-56

Genetic variants of the human obesity (OB) gene: association with body mass index in young women, psychiatric disorders, & interaction with the dopamine D2 receptor (DRD2) gene
Periodical: Molecular Psychiatry Index Medicus:
Authors: Comings DE, et al ART
Yr: 1996 Vol: 1 Nbr: Abs: Pg: 325-335

Polygenic inheritance and micro/minisatellites
Periodical: Molecular Psychiatry Index Medicus:
Authors: Comings DE ART
Yr: 0 Vol: Nbr: Abs: Pg: