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Passive Smoking and Clara Cell Development in the Lungs

Institution: University of California, Davis
Investigator(s): Kent Pinkerton, Ph.D.
Award Cycle: 1995 (Cycle 4) Grant #: 4RT-0213 Award: $442,317
Subject Area: Pulmonary Disease
Award Type: Research Project Awards
Abstracts
Publications

Sidestream cigarette smoke generation and exposure system for environmental tobacco smoke studies
Periodical: Index Medicus:
Authors: Teague SV, Pinkerton KE, Goldsmith M, et al ART
Yr: 1994 Vol: 6 Nbr: 1 Abs: Pg: 79-93

Decreased fetal weights in rats exposed to sidestream cigarette smoke
Periodical: Fundamental and Applied Toxicology Index Medicus:
Authors: Rajini P, Last JA, Pinkerton KE, Hendrickx AG, Witschi HP ART
Yr: 1994 Vol: 22 Nbr: 3 Abs: Pg: 400-404

Exposure to sidestream cigarette smoke alters bronchiolar epithelial cell differentiation in the postnatal rat lung
Periodical: American Journal of Respiratory Cell and Molecular Biology Index Medicus:
Authors: Ji CM, Plopper CG, Witschi HP, Pinkerton KE ART
Yr: 1994 Vol: 11 Nbr: 3 Abs: Pg: 312-320

Environmental tobacco smoke: experimental facts and societal issues
Periodical: Fundamental and Applied Toxicology Index Medicus:
Authors: Witschi HP, Pinkerton KE, Coggins CRE, Penn A, Synder CA, Gori GB ART
Yr: 1994 Vol: Nbr: Abs: Pg:

Characterization of aged and diluted sidestream cigarette smoke in animal exposure chambers
Periodical: Proceedings of the American Association for Aerosol Research Twelfth Annual Meeting Index Medicus:
Authors: Teague SV, Pinkerton KE, Goldsmith MR ABS
Yr: 1993 Vol: Nbr: Abs: Pg: 98

Induction of P450 isozyme 1A1 in developmental rat lung following exposure to environmental tobacco smoke
Periodical: Toxicologist Index Medicus:
Authors: Ji CM, Plopper CG, Pinkerton KE ABS
Yr: 1994 Vol: 14 Nbr: Abs: Pg: 52

ETS effects on perinatal lung development in rats
Periodical: Toxicologist Index Medicus:
Authors: Pinkerton KE, Ji CM, Gebremichael A, Buckpitt AR, Plopper CG ABS
Yr: 1994 Vol: 14 Nbr: Abs: Pg: 13

Comparison of the effect of filtered and non-filtered environmental tobacco smoke (ETS) on cytochrome P450(P450)1A1 and 2B1 activities in the rat lung and liver
Periodical: Toxicologist Index Medicus:
Authors: Gebremichael A, Buckpitt AR, Plopper CG, Pinkerton KE ABS
Yr: 1994 Vol: 14 Nbr: Abs: Pg: 424

Environmental tobacco smoke: experimental facts and societal issues
Periodical: Fundamental and Applied Toxicology Index Medicus:
Authors: Wtischi HP, Pinkerton KE, Coggins CRE, Penn A, Gori GB ART
Yr: 1995 Vol: 24 Nbr: 1 Abs: Pg: 3-12

Sidestream smoke effects on lung morphology and C-fibers in young guinea pigs
Periodical: Toxicology and Applied Pharmacology Index Medicus:
Authors: Joad JP, Bric JM, Pinkerton KE ART
Yr: 1995 Vol: 131 Nbr: 2 Abs: Pg: 289-296

In utero and postnatal effects of sidestream cigarette smoke exposure on lung function, hyperresponsiveness and neuroendocrine cells in rats
Periodical: Toxicology and Applied Pharmacology Index Medicus:
Authors: Joad JP, Kott KS, Bric JM, Pinkerton KE ART
Yr: 1995 Vol: 132 Nbr: 1 Abs: Pg: 63-71

Clara cell heterogeneity in differentiation: correlation with proliferation, ultrastructural composition and cell position in the rat bronchiole
Periodical: American Journal of Respiratory Cell and Molecular Biology Index Medicus:
Authors: Ji CM, Plopper CG, Pinkerton KE ART
Yr: 1995 Vol: 13 Nbr: 2 Abs: Pg: 144-151

Developmental expression of the pulmonary cytochrome P450 monoxygenase system during Clara cell differentiation in rats
Periodical: American Journal of Physiology Index Medicus:
Authors: Ji CM, Cardoso WV, Gebremichael A, et al ART
Yr: 1995 Vol: 13 Nbr: 3 Abs: Pg: L394-L402

Ah-receptor dependent modulation of gene expression by aged and diluted sidestream cigarette smoke
Periodical: Toxicologist Index Medicus:
Authors: Gebremichael A, Tullis K, Denison MS, Pinkerton KE ABS
Yr: 1995 Vol: 15 Nbr: Abs: Pg: 308

Six month exposure of strain A/J mice to cigarette sidestream smoke
Periodical: Toxicologist Index Medicus:
Authors: Witschi HP, Oreffo VI, Pinkerton KE ABS
Yr: 1995 Vol: 15 Nbr: Abs: Pg: 1065

Prenatal exposure to environmental tobacco smoke (ETS) in fetal rats increases expression of the Clara cell secretory protein
Periodical: American Journal of Respiratory and Critical Care Medicine Index Medicus:
Authors: Royce FH, Ji C, Yin J, Plopper CG, Pinkerton KE ABS
Yr: 1995 Vol: 151 Nbr: Abs: Pg: A2167

Clara cell heterogeneity in differentiation: correlation with proliferation, ultrastructural composition and cell position in the rat bronchiole
Periodical: American Journal of Respiratory and Critical Care Medicine Index Medicus:
Authors: Ji CM, Plopper CG, Pinkerton KE ABS
Yr: 1995 Vol: 151 Nbr: Abs: Pg: A302

Effects of environmental tobacco smoke exposure in utero and/or postnatally on brain development
Periodical: Pediatric Research Index Medicus:
Authors: Gospe SM, Zhou SS, Pinkerton KE ABS
Yr: 1995 Vol: 37 Nbr: Abs: Pg: 82A

Pulmonary cytochrome P-450 monooxygenase system and Clara cell differentiation in rats.
Periodical: American Journal of Physiology Index Medicus:
Authors: Ji CM, Cardoso WV, Gebremichael RM, et al ART
Yr: 1995 Vol: 269 Nbr: 13 Abs: Pg: L394-L402

Postnatal development of cytochrome P-4501A1 and 2B1 in rat lung and liver: effect of aged and diluted sidestream cigarette smoke
Periodical: Toxicology and Applied Pharmacology Index Medicus:
Authors: Gebremichael A, Chang AM, Buckpitt AR, Plopper CG, Pinkerton KE ART
Yr: 1995 Vol: 135 Nbr: Abs: Pg: 246-253

Ah-receptor dependent modulation of gene expression by aged and diluted sidestreatm cigarette smoke
Periodical: Toxicology and Applied Pharmacology Index Medicus:
Authors: Gebremichael A, Tullis K, Denison MS, Cheek JM, Pinkerton KE ART
Yr: 1996 Vol: 141 Nbr: Abs: Pg: 76-83

Effects of extended sidestream smoke exposure on components of the C-fiber axon reflex
Periodical: Toxicology Index Medicus:
Authors: Joad JP, Avadhanam KP, Watts KC, et al ART
Yr: 1996 Vol: 112 Nbr: Abs: Pg: 195-203

Effect of environmental tobacco smoke on LDL accumulation in the artery wall
Periodical: Circulation Index Medicus:
Authors: Roberts KA, Rezsai AA, Pinkerton KE, et al ART
Yr: 1996 Vol: 94 Nbr: Abs: Pg: 2248-2253

Quantitative histology and cytochrome P-450 immunocytochemistry of the lung parenchyma following 6 months of exposure of strain A/J mice to cigarette sidestream smoke
Periodical: Inhalation Toxicology Index Medicus:
Authors: Pinkerton KE, Peake JL, Espiritu I, et al ART
Yr: 1996 Vol: 8 Nbr: Abs: Pg: 927-945

Effects of environmental tobacco smoke exposure in utero and/or postnatally on brain development
Periodical: Pediatric Research Index Medicus:
Authors: Gospe SM, Zhou SS, Pinderton KE ART
Yr: 1996 Vol: 39 Nbr: Abs: Pg: 494-498

The toxiocology of environmental tobacco smoke
Periodical: Annual Review of Pharmacology and Toxicology Index Medicus:
Authors: Witschi HP, Joad JP, Pinkerton KE ART
Yr: 1997 Vol: 37 Nbr: Abs: Pg: 29-52

Mapping the distribution of neuroepithelial bodies of the rat lung: a whole-mount immunohistochemical approach
Periodical: American Journal of Pathology Index Medicus:
Authors: Avadhanam KP, Plopper CG, Pinkerton KE ART
Yr: 1997 Vol: 150 Nbr: Abs: Pg: 851-859

The carcinogenicity of environmental tobacco smoke
Periodical: Carcinogenesis Index Medicus:
Authors: Witschi HP, Espiritu I, Peake JL, et al ART
Yr: 1997 Vol: 18 Nbr: Abs: Pg: 575-586

Second-hand smoke is an adjuvant for T helper-2 responses in a murine model of allergy
Periodical: Journal of Immunology Index Medicus:
Authors: Seymour BWP, Pinkerton KE, Friebertshauser KE, Coffman RL, Gershwin LJ ART
Yr: 1997 Vol: 159 Nbr: Abs: Pg: 6169-6175

The carcinogenic potential of the gas phase of environmental tobacco smoke
Periodical: Carcinogenesis Index Medicus:
Authors: Witschi HP, Espiritu I, Maronpot RR, Pinkerton KE,Jones AD ART
Yr: 1997 Vol: 18 Nbr: Abs: Pg: 2035-2042

Site-selective differences in cytochrome P450 isoforms activities: comparison of expression in rat and rhesus monkey lung and induction in rats
Periodical: Drug Metabolism and Disposition Index Medicus:
Authors: Lee CH, Watt KC, Chang AM, Plopper CG, Singh G, Buckpitt AR, Pinkerton KE ART
Yr: 1998 Vol: 26 Nbr: Abs: Pg: 396-400

Maternal exposure to environmental tobacco smoke alters Clara cell secretory protein expression in fetal rat lung
Periodical: American Journal of Physiology Index Medicus:
Authors: Ji CM, Royce FH, Truong U, Plopper CG, Singh G, Pinkerton KE ART
Yr: 1998 Vol: 275 Nbr: 19 Abs: Pg: L870-L876

Six-month exposure to strain A/J mice to cigarette sidestream smoke: cell kinetics and lung tumor data
Periodical: Fundamental and Applied Toxicology Index Medicus:
Authors: Witschi H, Oreffo VIC, Pinkerton KE ART
Yr: 1995 Vol: 26 Nbr: Abs: Pg: 32-40