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Calorigenic and Atherogenic Effects of Smoking and Nicotine

Institution: University of California, San Francisco
Investigator(s): Marc Hellerstein, M.D., Ph.D.
Award Cycle: 1995 (Cycle 4) Grant #: 4RT-0233 Award: $357,492
Subject Area: Cardiovascular Disease
Award Type: Research Project Awards
Abstracts
Publications

Effects of cigarette smoking and its cessation on lipid metabolism and energy expenditure in heavy smokers
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Hellerstein MK, Benowitz NL, Neese RA, et al ART
Yr: 1994 Vol: 93 Nbr: 1 Abs: Pg: 265-272

Metabolic interactions between surplus dietary energy intake and cigarette smoking and its cessation
Periodical: American Journal of Physiology Index Medicus:
Authors: Neese RA, Benowitz NL, Hoh R, et al ART
Yr: 1994 Vol: 267 Nbr: 6 Pt 1 Abs: Pg: E1023-E1034

Quantification of periodicities in menstrual and diurnal rates of cholesterol and fat synthesis in humans
Periodical: Journal of Lipid Research Index Medicus:
Authors: Faix D, Neese RA, Kletke C, et al ART
Yr: 1993 Vol: 34 Nbr: 12 Abs: Pg: 2063-2075

Slower turnover of intermediate density lipoproteins and small low density lipoproteins in subclass pattern B
Periodical: Circulation Index Medicus:
Authors: Labelle M, Neese RA, Hellerstein MK, et al ART
Yr: 1993 Vol: Nbr: Abs: Pg:

Mass isotopomer distribution analysis (MIDA) for measuring gluconeogenesis (GNG): testing assumptions and potential theoretical and practical problems
Periodical: FASEB Journal Index Medicus:
Authors: Neese RA, Mills M, Schwarz J0M, Coutlangus M, Hellerstein MK ABS
Yr: 1994 Vol: 8 Nbr: 5 Abs: Pg: A919

Going forward in the determination of protein synthesis rates: measurement of accurate and precise isotope ratios of peptides
Periodical: FASEB Journal Index Medicus:
Authors: Cladwell KA, Papgeorgopoulos C, Siler SQ, Shackleton CHL, Hellerstein MK ABS
Yr: 1994 Vol: Nbr: Abs: Pg:

Divergent tolerance to metabolic and cardiovascular effects of nicotine in light and heavy cigarette smokers
Periodical: Clinical Pharmacology and Therapeutics Index Medicus:
Authors: Arcavi L, Jacob P, Hellerstein MK, Benowitz N ART
Yr: 1994 Vol: 56 Nbr: 1 Abs: Pg: 55-64

Measurement of gluconeogenesis and rate of appearance of intrahepatic triose-phosphate and its regulation by substrates by mass isotopomer distribution analysis (MIDA). Testing of assumptions and potential problems
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Neese RA, Faix D, Schwarz J-M, Turner SM, Vu D, Hellerstein MK ART
Yr: 1995 Vol: 270 Nbr: Abs: Pg: 14452-14463

Appendix. Calculations for gluconeogenesis by MIDA
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Neese RA, Hellerstein MK ART
Yr: 1995 Vol: 270 Nbr: Abs: Pg: 14464-14466

De novo hepatic lipogenesis (DNL) is a highly sensitive biomarker of energy balance in controlled dietary conditions in normal humans
Periodical: Diabetes Index Medicus:
Authors: Hellerstein MK, Schwartz J-M, Neese RA, et al ABS
Yr: 1994 Vol: 43 Nbr: Suppl 1 Abs: Pg: 48A

Striking metabolic effects of short-term changes in carbohydrate (CHO) energy intake in normal humans
Periodical: Clinical Research Index Medicus:
Authors: Hellerstein MK, Schwartz J-M, Neese RA, LaBua AB, Turner S ABS
Yr: 1995 Vol: Nbr: Abs: Pg:

Effects of caffeine on free fatty acid (FFA) metabolism in lean women
Periodical: FASEB Journal Index Medicus:
Authors: LaBua A, Benowitz N, Neese RA, Hellerstein MK ABS
Yr: 1995 Vol: 9 Nbr: Abs: Pg: A465

Contribution from gluconeogenesis (GNG) to fasting blood glucose measured by mass isotopomer distribution analysis (MIDA) in normal humans
Periodical: Diabetes Index Medicus:
Authors: Hellerstein M, Neese R, Linfoot P, Christiansen M, Turner S ABS
Yr: 1995 Vol: Nbr: Abs: Pg:

Rate of glucose entry into hepatic UDP-glucose by the direct pathway in fasted and fed states in normal humans
Periodical: Metabolism:Clinical and Experimental Index Medicus:
Authors: Hellerstein MK, Kaempfer S, Schwarz J-M, Wu K, Schakleton CHL ART
Yr: 1995 Vol: 44 Nbr: 2 Abs: Pg: 172-182

Short-term alterations in carbohydrate energy intake in humans: striking effects on hepatic glucose production, de novo lipogenesis, lipolysis and whole-body fuel selection
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Schwarz J-M, Neese RA, Turner S, Dare D, Hellerstein MK ART
Yr: 1995 Vol: 96 Nbr: Abs: Pg: 2735-2743

Measurement of triglyceride, cholersterol and apolipoprotein synthesis in vivo: recent developments ith stable isotopes and mass spectrometry
Periodical: European Journal of Clinical Investigation Index Medicus:
Authors: Hellerstein MK ART
Yr: 1996 Vol: Nbr: Abs: Pg:

Synthesis of fat in response to alterations in diet: insights from new stable isotope methodologies
Periodical: Lipids Index Medicus:
Authors: Hellerstein MK ART
Yr: 1996 Vol: Nbr: Abs: Pg:

Regulation of hepatic de novo lipogenesis in humans
Periodical: Annual Review of Nutrition Index Medicus:
Authors: Hellerstein MK, Scharz J-M, Neese RA ART
Yr: 1996 Vol: Nbr: Abs: Pg: