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Function and Regulation of the Retinoblastoma Protein

Institution: University of California, San Diego
Investigator(s): James Feramisco, Ph.D.
Award Cycle: 1995 (Cycle 4) Grant #: 4RT-0251 Award: $385,031
Subject Area: Cancer
Award Type: Research Project Awards
Abstracts
Publications

Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity
Periodical: Molecular and Cellular Biology Index Medicus:
Authors: Frost JA, Alberts AS, Sontag E, Guan KL, Mumby MC, Feramisco JR ART
Yr: 1994 Vol: 14 Nbr: 9 Abs: Pg: 6244-6252

Binding of Shc to the NPXY motif is mediated by its N-terminal domain
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Prigent SA, Pillay TS, Ravichandran KS, Gullick WJ ART
Yr: 1995 Vol: 270 Nbr: 38 Abs: Pg: 22097-22100

Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated EGF receptor is mediated by the RAS-SHC-GRB2 pathway
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Prigent SA, Nangene M, Lin H, et al ART
Yr: 1996 Vol: 271 Nbr: Abs: Pg: 25639-25645

Inhibition of RAF-1 signaling by a monoclonal antibody which interferes with RAF-1 activation and with MEK substrate binding
Periodical: Oncogene Index Medicus:
Authors: Kolch W, Philipp A, Mischak H, et al ART
Yr: 1996 Vol: 13 Nbr: Abs: Pg: 1305-1314

Identification of genes regulated by ERBb3 by RDA
Periodical: Biochemical Journal Index Medicus:
Authors: Prigent SA, Edman C, Schipper A, et al ART
Yr: 1997 Vol: Nbr: Abs: Pg:

Elevated expression of cyclins and cyclin-dependent kinases in the rhabdomyosarcoma cell line RD
Periodical: Cancer Research Index Medicus:
Authors: Knudsen ES, Pazzagil C, Born TL, et al ART
Yr: 1998 Vol: 58 Nbr: Abs: Pg: 2042-2049

Inhibition of DNA synthesis by RB: distinct effects on the GI/S transition and on S-phase progression
Periodical: Genes and Development Index Medicus:
Authors: Knudsen ES, Buchmaster C, Chen T, Feramisco JJR, Wang JYJ ART
Yr: 1998 Vol: 12 Nbr: Abs: Pg: 2278-2292

Retinoic acid-mediated growth inhibition of two human small cell lung cancer cell lines is associated by myc downregulation and p27Kip 1 induction
Periodical: International Journal of Cancer Index Medicus:
Authors: Weber E, Ravi R, Knudsen E, et al ART
Yr: 1999 Vol: 80 Nbr: Abs: Pg: 935-943

The retinoblastoma tumor suppressor inhibits proliferation through two distinct mechanisms: inhibition of cell cycle progression and induction of cell death
Periodical: Oncogene Index Medicus:
Authors: Knudsen K, Weber E, Arden K, Cavenee W, Feramisco J, Knudsen E ART
Yr: 1999 Vol: 18 Nbr: Abs: Pg: 5239-5245