Research Portfolio

Funding Opportunities

Join our Mailing List
Join our mailing list to be notified of new funding opportunities.

Your Email

To receive information about funding opportunities, events, and program updates.

Function and Regulation of the Retinoblastoma Protein

Institution: University of California, San Diego
Investigator(s): James Feramisco, Ph.D.
Award Cycle: 1995 (Cycle 4) Grant #: 4RT-0251 Award: $385,031
Subject Area: Cancer
Award Type: Research Project Awards

Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity
Periodical: Molecular and Cellular Biology Index Medicus:
Authors: Frost JA, Alberts AS, Sontag E, Guan KL, Mumby MC, Feramisco JR ART
Yr: 1994 Vol: 14 Nbr: 9 Abs: Pg: 6244-6252

Binding of Shc to the NPXY motif is mediated by its N-terminal domain
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Prigent SA, Pillay TS, Ravichandran KS, Gullick WJ ART
Yr: 1995 Vol: 270 Nbr: 38 Abs: Pg: 22097-22100

Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated EGF receptor is mediated by the RAS-SHC-GRB2 pathway
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Prigent SA, Nangene M, Lin H, et al ART
Yr: 1996 Vol: 271 Nbr: Abs: Pg: 25639-25645

Inhibition of RAF-1 signaling by a monoclonal antibody which interferes with RAF-1 activation and with MEK substrate binding
Periodical: Oncogene Index Medicus:
Authors: Kolch W, Philipp A, Mischak H, et al ART
Yr: 1996 Vol: 13 Nbr: Abs: Pg: 1305-1314

Identification of genes regulated by ERBb3 by RDA
Periodical: Biochemical Journal Index Medicus:
Authors: Prigent SA, Edman C, Schipper A, et al ART
Yr: 1997 Vol: Nbr: Abs: Pg:

Elevated expression of cyclins and cyclin-dependent kinases in the rhabdomyosarcoma cell line RD
Periodical: Cancer Research Index Medicus:
Authors: Knudsen ES, Pazzagil C, Born TL, et al ART
Yr: 1998 Vol: 58 Nbr: Abs: Pg: 2042-2049

Inhibition of DNA synthesis by RB: distinct effects on the GI/S transition and on S-phase progression
Periodical: Genes and Development Index Medicus:
Authors: Knudsen ES, Buchmaster C, Chen T, Feramisco JJR, Wang JYJ ART
Yr: 1998 Vol: 12 Nbr: Abs: Pg: 2278-2292

Retinoic acid-mediated growth inhibition of two human small cell lung cancer cell lines is associated by myc downregulation and p27Kip 1 induction
Periodical: International Journal of Cancer Index Medicus:
Authors: Weber E, Ravi R, Knudsen E, et al ART
Yr: 1999 Vol: 80 Nbr: Abs: Pg: 935-943

The retinoblastoma tumor suppressor inhibits proliferation through two distinct mechanisms: inhibition of cell cycle progression and induction of cell death
Periodical: Oncogene Index Medicus:
Authors: Knudsen K, Weber E, Arden K, Cavenee W, Feramisco J, Knudsen E ART
Yr: 1999 Vol: 18 Nbr: Abs: Pg: 5239-5245