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Developmental Relationship between NK and T-Cell Lineages

Institution: California Institute of Technology
Investigator(s): Ellen Rothenberg, Ph.D.
Award Cycle: 1995 (Cycle 4) Grant #: 4RT-0264 Award: $434,126
Subject Area: Cancer
Award Type: Research Project Awards
Abstracts
Publications

A dynamic assembly of diverse transcription factors integrates activation and cell-type information for interleukin-2 gene regulation
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Rothenberg EV, Ward SB ART
Yr: 1996 Vol: 93 Nbr: Abs: Pg: 9358-9365

Different developmental arrest points in RAG-2-/- and scid thymocytes on two genetic backgrounds: developmental choices and cell death mechanisms before TCR gene rearrangement
Periodical: Journal of Immunology Index Medicus:
Authors: Diamond RA, Ward SB, Owada-Makabe K, et al ART
Yr: 1997 Vol: 158 Nbr: Abs: Pg: 4052-4064

Cross-lineage expression of Ig-b (B29) in thymocytes: positive and negative gene regulation to establish T-cell identity
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Wang H, Diamond RA, Rothenberg EV ART
Yr: 1995 Vol: 95 Nbr: Abs: Pg: 6831-6836

Chromatin remodeling of the interleukin-2 gene: distinct alterations in the proximal versus distal enhancer regions
Periodical: Nucleic Acids Research Index Medicus:
Authors: Ward SB, Hernandez-Hoyos G, Chen F, et al ART
Yr: 26 Vol: Nbr: Abs: Pg: 2923-2934

Precocious expression of T-cell functional response genes in vivo iiin primitive thymocytes before T-lineage commitment
Periodical: International Immunology Index Medicus:
Authors: Wang H, Diamond RA, Yang-Snyder JA, Rothenberg EV ART
Yr: 10 Vol: Nbr: Abs: Pg: 1623-1635

Expression and function of a stem-cell promoter for the murine CBFa2 gene: distinct roles and regulation in natural killer and T-cell development
Periodical: Developmental Biology Index Medicus:
Authors: Telfer JC, Rotherberg EV ART
Yr: 2001 Vol: 229 Nbr: Abs: Pg: 363-382