| Tobacco  use remains a leading cause of death and disease in California. Young adults  smoke in high numbers and are interested in quitting, but they are less likely  to use effective smoking cessation services. Smartphones are widely used among  this group and offer a promising strategy to deliver smoking cessation  interventions to a large, diverse audience of young adult smokers. Smoking  cessation applications for smartphones are rarely based on proven and effective  smoking cessation interventions. Further, only a few of these applications  deliver customized content to meet the specific needs of each individual  smoker. Little is known about how smartphone-based interventions need to be  designed, and what kind of custom-made content they should deliver. One especially  promising strategy is to target situations that elicit smoking urges. Urges are  important triggers for smoking, so it is important for smoking cessation  messages to help young adults cope with these urges.  The  applicant has experience conducting smartphone-based studies to investigate  real-world triggers for smoking among young adults and he has worked on smoking  cessation interventions for young people using in-person counseling and social  media. He aims to combine these lines of research to develop new  smartphone-based interventions for smoking cessation. His career plan includes  training in human centered design to develop smartphone messages, conducting  mobile health (mHealth, i.e. using mobile devices for health care) intervention studies, basics in machine learning and predictive  modeling, and to expand his skills in quantitative and qualitative research  methods. The  UCSF Center for Tobacco Control Research and Education provides an exceptional  environment for developing tobacco investigators. The primary mentor, Dr.  Pamela Ling, is an expert in tobacco research with young adults, and the other  members of the mentoring and advisory team provide additional expertise in  smoking cessation, mHealth methods for health behavior change, intervention development,  and mHealth trial design. The overall goal of the proposed research is to  develop and pilot test messages to reduce smoking urges among young adult  smokers. The  specific aims are: Aim 1) Describe situational triggers for smoking for young  adults by analyzing real-time data from 150 young adult smokers collected in  smartphone assessments. The applicant is currently conducting this study and he  will analyze the data to determine the most important situational triggers for  smoking among young adults. Aim 2.1) Develop and design smartphone-based  smoking cessation messages for young adults based on the US Clinical Practice  Guidelines for smoking cessation and informed by a social media smoking  cessation intervention the applicant has conducted. Further (Aim 2.2), to  demonstrate acceptability and understanding of the intervention messages among  the target audience through focus groups with 20 participants. Aim 3) Usability  test the intervention with 20 young adult smokers in a 30-day micro-randomized  pilot trial. In  this novel type of trial, each participant receives multiple intervention  messages over time. Intervention messages of three randomly selected types  (matched to situation, mismatched to situation, or control) will be delivered  to each participant’s smartphone 3 times per day. Messages may be matched to  situations where participants report strong urges to smoke, or to locations  (based on phone geolocation data) where smoking occurs. An existing software  platform will be used for the smartphone-based interventions. The pilot trial  will examine ease of participant recruitment, how well participants comply with  study procedures, how well the matching of intervention messages works, how  useful participants find the intervention messages, and will provide initial  data on how effective the matched messages work for reducing urges.  Results  of this study will generate important pilot data for a future proposal to  conduct a larger trial to determine how effective the developed intervention  messages are for decreasing smoking urges and smoking behavior.  |