Research Portfolio

Funding Opportunities

Join our Mailing List
Join our mailing list to be notified of new funding opportunities.

Your Email

To receive information about funding opportunities, events, and program updates.



Understanding Nicotinic Receptor Subtype Specificity

Institution: California Institute of Technology
Investigator(s): Dennis Dougherty,
Award Cycle: 2007 (Cycle 16) Grant #: 16RT-0160 Award: $592,751
Subject Area: Nicotine Dependence
Award Type: Research Project Awards
Abstracts
Publications

Cys-loop neuroreceptors: structure to the rescue?
Periodical: Chemical Reviews Index Medicus:
Authors: Dougherty, DA ART
Yr: 2008 Vol: 108 Nbr: 5 Abs: Pg: 1642-1653

Physical organic chemistry on the brain
Periodical: Journal of Organics Chemistry Index Medicus:
Authors: ART
Yr: 2008 Vol: 73 Nbr: 10 Abs: Pg: 3667-3673

Nicotine binding to brain receptors requires a strong cation-pi interaction
Periodical: Nature Index Medicus:
Authors: Xiu X, Puskar NL, Shanata JP, Lester HA, Dougherty DA ART
Yr: 2009 Vol: Nbr: 458 Abs: Pg: 534-537

The nicotine pharmacophore: the polar groups of ACh and nicotine hydrogen bond across a submit interface to a backbone NH
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Blum, AP; Lester,HA; Dougherty, J ART
Yr: 2010 Vol: Nbr: 107 Abs: Pg: 13206-13211

Cys-loop neuroreceptors: structure to the rescue?
Periodical: Chemical Reviews Index Medicus:
Authors: Dougherty, DA ART
Yr: 2008 Vol: 108 Nbr: 5 Abs: Pg: 1642-1653

Physical organic chemistry on the brain
Periodical: Journal of Organics Chemistry Index Medicus:
Authors: ART
Yr: 2008 Vol: 73 Nbr: 10 Abs: Pg: 3667-3673

Nicotine binding to brain receptors requires a strong cation-pi interaction
Periodical: Nature Index Medicus:
Authors: Xiu X, Puskar NL, Shanata JP, Lester HA, Dougherty DA ART
Yr: 2009 Vol: Nbr: 458 Abs: Pg: 534-537

The nicotine pharmacophore: the polar groups of ACh and nicotine hydrogen bond across a submit interface to a backbone NH
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Blum, AP; Lester,HA; Dougherty, J ART
Yr: 2010 Vol: Nbr: 107 Abs: Pg: 13206-13211