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What is the local lung dose of smoke from emerging tobacco products?

Institution: University of California, Davis
Investigator(s): Anthony Wexler,
Award Cycle: 2019 (Cycle 30) Grant #: T30IR0955 Award: $935,724
Subject Area: Environmental Exposure/Toxicology
Award Type: High Impact Research Project Award

Initial Award Abstract
As cigarette use remains stable or possibly slightly declines in the US, the use of alternative products increases. This proposal will measure the dose of smoke from two of these alternatives, little cigars, regionally throughout the lungs of rats with the goal of improving the performance of mathematical models that predict dose in humans. The resulting model will be public domain so investigators can explore dose of these alternatives and their implications for health and addiction.