Daniel Broek, Ph.D.
| University of Southern California | # of Grants: 1 |
Grants
| Structure-function studies of RAS nucleotide-exchange-factor | 1993 (Cycle 2) | $593,460 |
| Cancer | Research Project Awards | |
Publications
| Functional cloning of BUD5, a CDC25-related gene from S. cerevisiae that can suppress a dominant-negative RAS2 mutant | ||||
| Periodical: Cell | Index Medicus: | |||
| Authors: Powers S, Gonzales E, Christenson T, Cubert J, Broek D | ART | |||
| Yr: 1991 | Vol: 65 | Nbr: 7 | Abs: | Pg: 1225-1231 |
| Identification and analysis of a DNA fragment from Saccaromyces Kluyver then can complement the loss of CDC25 function in Saccharomyces cerevisiae | ||||
| Periodical: Gene | Index Medicus: | |||
| Authors: Prigozy T, Gonzales E, Broek D | ART | |||
| Yr: 0 | Vol: | Nbr: | Abs: | Pg: |
| Involvement of p34cdc2 in establishing the dependency of S-phase on mitosis | ||||
| Periodical: Nature | Index Medicus: | |||
| Authors: Broek D, Bartlett R, Crawford K, Nurse P | ART | |||
| Yr: 1991 | Vol: 349 | Nbr: 6308 | Abs: | Pg: 388-393 |
| Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae | ||||
| Periodical: Proceedings of the National Academy of Sciences of the United States of America | Index Medicus: | |||
| Authors: Wei W, Mosteller RD, Sangal P, et al | ART | |||
| Yr: 1992 | Vol: 89 | Nbr: 15 | Abs: | Pg: 7100-7104 |
| Influence of guanine-nucleotides on complex formation between Ras and cdc25 proteins | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Lai C-C, Broek D, Powers S | ART | |||
| Yr: 1993 | Vol: 13 | Nbr: 3 | Abs: | Pg: 1345-1352 |
| Yeast cells can center a quiescent state through G1-,S-,G2-, or M-phase of the cell cycle | ||||
| Periodical: Cancer Research | Index Medicus: | |||
| Authors: Wei W, Nurse P, Broek D | ART | |||
| Yr: 1993 | Vol: 53 | Nbr: 8 | Abs: | Pg: 1867-1870 |
| Localization of the cellular expression pattern of CDC25 and ras in neonatal rat brain | ||||
| Periodical: Brain Research. Molecular Brain Research | Index Medicus: | |||
| Authors: Wei W, Schreiber SS, Baudry M, Tocco G, Broek D | ART | |||
| Yr: 1993 | Vol: 19 | Nbr: 4 | Abs: | Pg: 339-344 |
| The catalytic domain of the mouse SOS1 gene product activates Ras proteins in vivo and in vitro | ||||
| Periodical: Oncogene | Index Medicus: | |||
| Authors: Liu BX, Wei W, Broek D | ART | |||
| Yr: 1993 | Vol: 8 | Nbr: 11 | Abs: | Pg: 3081-3084 |
| Identification of residues of the H-ras protein critical for functional interaction with nucleotide-exchange factors | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Mosteller R, Han J, Broek D | ART | |||
| Yr: 1994 | Vol: 14 | Nbr: 2 | Abs: | Pg: 1104-1112 |
| Genetic and biochemical characterization of a novel dominant negative mutant that interferes with alternate activators of ras in schizosaccharomyces pombe and saccharomyces cerevisiae | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Jung V, Wei W, Camonis J, et al | ART | |||
| Yr: 1994 | Vol: 14 | Nbr: 6 | Abs: | Pg: 3707-3718 |
| Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity | ||||
| Periodical: Proceedings of the National Academy of Sciences of the United States of America | Index Medicus: | |||
| Authors: Quilliam LA, Huff SY, Rubin KM, et al | ART | |||
| Yr: 1994 | Vol: 91 | Nbr: 18 | Abs: | Pg: 8512-8516 |
| Amino acid residues in the CDC25 guanine nucleotide exchange factor critical for interaction with Ras | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Park W, Mosteller R, Broek D | ART | |||
| Yr: 1994 | Vol: 14 | Nbr: 12 | Abs: | Pg: 8117-8122 |
| Identification and characterization of alternately spliced cdc25 cDNAs from human brain | ||||
| Periodical: Gene | Index Medicus: | |||
| Authors: Wei W, Das B, Park W, Broek D | ART | |||
| Yr: 1994 | Vol: 151 | Nbr: 1-2 | Abs: | Pg: 279-284 |
| Analysis of the interaction between Ras and CDC25 guanine nucleotide exchange factor using the yeast GAL4 two-hybrid system | ||||
| Periodical: Methods in Enzymology | Index Medicus: | |||
| Authors: Mosteller RD, Park W, Broek D | ART | |||
| Yr: 1995 | Vol: 255 | Nbr: | Abs: | Pg: 135-148 |
| Functional cloning of BUD5, a CDC25-related gene from S. cerevisiae that can suppress a dominant-negative RAS2 mutant | ||||
| Periodical: Cell | Index Medicus: | |||
| Authors: Powers S, Gonzales E, Christenson T, Cubert J, Broek D | ART | |||
| Yr: 1991 | Vol: 65 | Nbr: 7 | Abs: | Pg: 1225-1231 |
| Identification and analysis of a DNA fragment from Saccaromyces Kluyver then can complement the loss of CDC25 function in Saccharomyces cerevisiae | ||||
| Periodical: Gene | Index Medicus: | |||
| Authors: Prigozy T, Gonzales E, Broek D | ART | |||
| Yr: 0 | Vol: | Nbr: | Abs: | Pg: |
| Involvement of p34cdc2 in establishing the dependency of S-phase on mitosis | ||||
| Periodical: Nature | Index Medicus: | |||
| Authors: Broek D, Bartlett R, Crawford K, Nurse P | ART | |||
| Yr: 1991 | Vol: 349 | Nbr: 6308 | Abs: | Pg: 388-393 |
| Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae | ||||
| Periodical: Proceedings of the National Academy of Sciences of the United States of America | Index Medicus: | |||
| Authors: Wei W, Mosteller RD, Sangal P, et al | ART | |||
| Yr: 1992 | Vol: 89 | Nbr: 15 | Abs: | Pg: 7100-7104 |
| Influence of guanine-nucleotides on complex formation between Ras and cdc25 proteins | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Lai C-C, Broek D, Powers S | ART | |||
| Yr: 1993 | Vol: 13 | Nbr: 3 | Abs: | Pg: 1345-1352 |
| Yeast cells can center a quiescent state through G1-,S-,G2-, or M-phase of the cell cycle | ||||
| Periodical: Cancer Research | Index Medicus: | |||
| Authors: Wei W, Nurse P, Broek D | ART | |||
| Yr: 1993 | Vol: 53 | Nbr: 8 | Abs: | Pg: 1867-1870 |
| Localization of the cellular expression pattern of CDC25 and ras in neonatal rat brain | ||||
| Periodical: Brain Research. Molecular Brain Research | Index Medicus: | |||
| Authors: Wei W, Schreiber SS, Baudry M, Tocco G, Broek D | ART | |||
| Yr: 1993 | Vol: 19 | Nbr: 4 | Abs: | Pg: 339-344 |
| The catalytic domain of the mouse SOS1 gene product activates Ras proteins in vivo and in vitro | ||||
| Periodical: Oncogene | Index Medicus: | |||
| Authors: Liu BX, Wei W, Broek D | ART | |||
| Yr: 1993 | Vol: 8 | Nbr: 11 | Abs: | Pg: 3081-3084 |
| Identification of residues of the H-ras protein critical for functional interaction with nucleotide-exchange factors | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Mosteller R, Han J, Broek D | ART | |||
| Yr: 1994 | Vol: 14 | Nbr: 2 | Abs: | Pg: 1104-1112 |
| Genetic and biochemical characterization of a novel dominant negative mutant that interferes with alternate activators of ras in schizosaccharomyces pombe and saccharomyces cerevisiae | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Jung V, Wei W, Camonis J, et al | ART | |||
| Yr: 1994 | Vol: 14 | Nbr: 6 | Abs: | Pg: 3707-3718 |
| Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity | ||||
| Periodical: Proceedings of the National Academy of Sciences of the United States of America | Index Medicus: | |||
| Authors: Quilliam LA, Huff SY, Rubin KM, et al | ART | |||
| Yr: 1994 | Vol: 91 | Nbr: 18 | Abs: | Pg: 8512-8516 |
| Amino acid residues in the CDC25 guanine nucleotide exchange factor critical for interaction with Ras | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Park W, Mosteller R, Broek D | ART | |||
| Yr: 1994 | Vol: 14 | Nbr: 12 | Abs: | Pg: 8117-8122 |
| Identification and characterization of alternately spliced cdc25 cDNAs from human brain | ||||
| Periodical: Gene | Index Medicus: | |||
| Authors: Wei W, Das B, Park W, Broek D | ART | |||
| Yr: 1994 | Vol: 151 | Nbr: 1-2 | Abs: | Pg: 279-284 |
| Analysis of the interaction between Ras and CDC25 guanine nucleotide exchange factor using the yeast GAL4 two-hybrid system | ||||
| Periodical: Methods in Enzymology | Index Medicus: | |||
| Authors: Mosteller RD, Park W, Broek D | ART | |||
| Yr: 1995 | Vol: 255 | Nbr: | Abs: | Pg: 135-148 |