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Sherven Sharma, Ph.D.

University of California, Los Angeles # of Grants: 2

Grants

Chemokine-based therapy for lung cancer 2001 (Cycle 10) $416,940
Cancer Research Project Awards

Immune Targeted Therapy for Lung Cancer 2006 (Cycle 15) $419,500
Cancer Research Project Awards
Publications

SLC reduces pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma.
Periodical: Cancer Research Index Medicus:
Authors: Sharma S, Stolina M, Zhu L, Lin Y, Batra RK, Huang M, Strieter R, and Dubinett SM ART
Yr: 2991 Vol: 61 Nbr: 17 Abs: Pg: 6406-12

Non-small cell lung cancer cyclooxygenase-2-dependent invasion is mediated by CD44.
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Dohadwala M, Luo J, Lin Y Dougherty GJ, Sharma S, Huang M, Pold M, Batra RK, Dubinett SM ART
Yr: 2001 Vol: 276 Nbr: 24 Abs: Pg: 20809-12

Ectopic expression of the thyroperoxidase gene augments radiolodide uptake and retention mediated by the socium iodide symporter in non-small cell lung cancer.
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Hunag M, Batra RK, Kogai T, Lin YQ, Hershman JM, Lichtenstein A, Sharma S, et al ART
Yr: 2000 Vol: 97 Nbr: 15 Abs: Pg: 8519-24

SLC/CCL21-mediated anti-tumor responses require IFNy, MIG/CXCL9 and IP-10/CXCL10.
Periodical: Molecular Cancer Research Index Medicus:
Authors: Sharma S, Yang SC, Hillinger S, Zhu L, Huang M, Batra RK, Lin JF, Burdick MD, et al ART
Yr: 2003 Vol: 2 Nbr: 1 Abs: Pg: 22

Tumor COX-2 dependent regulation of murine dendritic cell function.
Periodical: Clinical Cancer Research Index Medicus:
Authors: Sharma S, Stolina M, Baratelli F, Lin JF, Atianzar K, Zhu L, Lin Y, et al ART
Yr: 2003 Vol: 9 Nbr: Abs: Pg: 961-968

Non-small cell lung cancer-derived soluble mediators enhance apoptosis in T lymphocytes through an I kappa B kinase-dependent mechanism.
Periodical: Cancer Research Index Medicus:
Authors: Batra R, Lin Y, Gardner B, Luo J, Dohadwala M, Sharma S, Dubinett SM ART
Yr: 2003 Vol: 63 Nbr: Abs: Pg: 642-646

Abnormal IL-10Ralpha expression contributes to the maintenance of elevated COX-2 in non-small cell lung cancer cells.
Periodical: Cancer Research Index Medicus:
Authors: Heuze-Vourc'h N, Krysan K, Batra RK, Sharma S, Dubinett SM ART
Yr: 2003 Vol: 63 Nbr: Abs: Pg: 766-770

IL-10 mediates the sigma receptor-dependent suppression of antitumor immunity.
Periodical: Journal of Immunology Index Medicus:
Authors: Zhu LX, Sharma S, Gardner B, Escuadro B, Atianzar K, Tashkin D, Dubinett SM ART
Yr: 2003 Vol: 170 Nbr: Abs: Pg: 3585-3591

Secondary lymphoid tissue chemokine mediates T cell-dependent antitumor responses in vivo.
Periodical: Journal of Immunology Index Medicus:
Authors: Sharma S, Stolina M, Luo J, Strieter RM, Burdick M, Zhu LI, Batra RK, Dubinett SM ART
Yr: 2000 Vol: 164 Nbr: Abs: Pg: 4558 - 4563

Secondary lymphoid organ chemokine reduces pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma.
Periodical: Cancer Research Index Medicus:
Authors: Sharma S, Stolina M, Zhu L, Lin Y, Batra R, Huang M Strieter R, Dubinett SM ART
Yr: 2001 Vol: 1;61 Nbr: 17 Abs: Pg: 6406 - 6412

Over expression of CCL-21/Secondary lymphoid tissue chemokine in human dendritic cells augments patacrine chemotactic activities for lymphocytes and antigen presenting cells.
Periodical: Molecular Cancer Research Index Medicus:
Authors: Sharma S, Riedl K, Baratelli F, Batra RK, Yang SC, Luo J, Escuadro B, Figlin R, et al. ART
Yr: 2003 Vol: 2 Nbr: Abs: Pg: 35

Cyclooxygenase 2-dependent regulation of antitumor immunity in lung cancer.
Periodical: Methods in Molecular Medicine Index Medicus:
Authors: Sharma S, Huang M, Dohadwala M, Pold M, Batra RK, Dubinett SM, et al. ART
Yr: 2003 Vol: 75 Nbr: Abs: Pg: 723 - 736

Intratumoral therapy with cytokine gene-modified dentritic cells in murine lung cancer models.
Periodical: Methods in Molecular Medicine Index Medicus:
Authors: Sharma S, Yang SC, Batra RK, Dubinett SM ART
Yr: 2003 Vol: 75 Nbr: Abs: Pg: 711 - 722

EBV-induced molecule 1 ligand chemokine (ELC/CCL19) promotes IFN-gamma-dependent antitumor responses in a lung cancer model.
Periodical: Journal of Immunology Index Medicus:
Authors: Sharma S, Hillinger S, Yang SC, Zhu L, Huang M Duckett R, Atianzar K, Batra RK, et al. ART
Yr: 2003 Vol: 171 Nbr: 12 Abs: Pg: 6457 - 6465

Interleukin-7 gene-modified dendritic cells reduce pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma.
Periodical: Human Gene Therapy Index Medicus:
Authors: Sharma S, Batra RK, Yang SC, Hillinger S, Zhu L, Atianzar K, Strieter RM, et al ART
Yr: 2003 Vol: 14 Nbr: 16 Abs: Pg: 1511 - 1524

Tumor cyclooxygenase 2-dependent suppression of dendritic cell function.
Periodical: Clinical Cancer Research Index Medicus:
Authors: Sharma S, Stolina M, Yang SC, Baratelli F, Lin JF, Atianzar K, Luo J, Zhu L, Lin Y, et al. ART
Yr: 2003 Vol: 9 Nbr: 3 Abs: Pg: 961 - 968

Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity.
Periodical: Clinical Cancer Research Index Medicus:
Authors: Sharma S, Yang SC, Hillinger S, Riedl K, Zhang L, Zhu L, Huang M, Atianzar K, et al. ART
Yr: 2004 Vol: 10 Nbr: 8 Abs: Pg: 2891 - 2901

Tumor COX-2/PGE2 dependent promotion of FOXP3 expression and CD4+CD25+ T regulatory cell activities in lung cancer.
Periodical: Cancer Research Index Medicus:
Authors: Sharma S, Yang SC, Zhu L, Reckamp K, Gardner B, Baratelli F, Zhang L, Huang M, et al. ART
Yr: 2005 Vol: 65 Nbr: 14 Abs: Pg: 6275 - 6281

COX-2 inhibition promotes IFNy-dependent enhancement of anti-tumor immunity.
Periodical: Journal of Immunology Index Medicus:
Authors: Sharma S, Zhu L, Hillinger S, Yang SC, Gardner B, Kuo B, Reckamp K. Strieter RM, et al. ART
Yr: 2005 Vol: 175 Nbr: 2 Abs: Pg: 813 - 819

PGE2 induces FOXP3 gene expression and T regulatory function in human CD4+ T cells.
Periodical: Journal of Immunology Index Medicus:
Authors: Sharma S, Baratelli F, Lin Y, Zhu L, Yang SC, Heuze-Voure'h N, Zeng G, et al. ART
Yr: 2005 Vol: 175 Nbr: 3 Abs: Pg: 1483 - 1490

CXC chemokines: angiogenesis, immunoangiostasis, and metastases in lung cancer.
Periodical: Annals of the New York Academy of Sciences Index Medicus:
Authors: Sharma S, Strieter RM, Belperio JA, Burdick MD, Dubinett SM Keane MP ART
Yr: 2004 Vol: 1028 Nbr: Abs: Pg: 351 - 360

Intrapulomonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinoma
Periodical: Cancer Research Index Medicus:
Authors: Yang, S.C., Batra, R.K., Hillinger, S., Rekamp, K.L., Strieter, R.M., Dubinett, S., Sharma ART
Yr: 2006 Vol: 66 Nbr: 6 Abs: Pg: 3205-13

CCl19 reduces tumour burden in a model of advanced lung cancer
Periodical: British Journal of Cancer Index Medicus:
Authors: Hillinger, S., Yang, S.C., Btra, R.K., Strieter, R.M., Weder, W., Dubinett, S.M, Sharma, S ART
Yr: 2006 Vol: 94 Nbr: 7 Abs: Pg: 1029-34

Inflammation in lung carcinogenesis: new targets for lung cancer chemoprevention and treatment
Periodical: Critical Reviews in Oncology/Hematolgy Index Medicus:
Authors: Lee, J.M., Yanagawa, J., Peebles, K.A., Sharma, S., Mao, J.T., Dubinett, S.M. ART
Yr: 2008 Vol: 66 Nbr: 3 Abs: Pg: 208-17

Tumor response to combination celecoxib and erlotinib therapy in no-smal cell lung cancer is assocated with a low baseline matrix mettalloproteinase-9 and a decline in serum-soluable E-caderherin
Periodical: Journal of Thoracic Oncology Index Medicus:
Authors: Reckamp, K.L, Gardner, B.K., Figlin, R.A., Elashoff, D., Kryasan, K., Dohadwala, M., Mao, ART
Yr: 2008 Vol: 2 Nbr: Abs: Pg: 117-24

Immunolgic Approaches to Lung Cancer Therapy
Periodical: Lung Cancer Index Medicus:
Authors: Lee, J.M., Dubinett, S.M., Sharma, S. ART
Yr: 2007 Vol: 3 Edition Nbr: Abs: Pg:

Inflammation and lung carcinogenesis: applying new findings in prevention and treatment
Periodical: Expert Review of Anticancer Therapy Index Medicus:
Authors: Peebles, K.A., Lee, J.M., Mao, J.T., Harza, S., Reckamp, K.L., Krysa, K., Dohadwala, M., ART
Yr: 2007 Vol: 7 Nbr: 10 Abs: Pg: 1405-21

IL-7 promotes CXCR3 ligand-dependent T cell antitumor reactivity in lung cancer.
Periodical: Journal of Immunology Index Medicus:
Authors: Anderson A,Yang S, Huang M, Zhu L, Kar U, Batra R, Elashoff D;StrieterR;Dubinett S SharmaS ART
Yr: 2009 Vol: 182 Nbr: 11 Abs: Pg: 6951-6958