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Maryka Quik, Ph.D.

SRI International # of Grants: 7

Grants

Role of nicotine/nicotinic receptors in Parkinson's disease 1998 (Cycle 7) $644,770
Nicotine Dependence Research Project Awards

Role of nicotine in neuro protection 1999 (Cycle 8) $722,263
Nicotine Dependence Research Project Awards

Nicotinic receptors and Parkinson's disease 2002 (Cycle 11) $376,470
Nicotine Dependence Research Project Awards

Society for Neuroscience Nicotinic Receptors Meeting 2007 (Cycle 16) $10,000
Nicotine Dependence Special Projects

Chronic nicotine treatment in primates; role of a6b2 nAChRs 2008 (Cycle 17) $194,628
Nicotine Dependence Research Project Awards

Society for Neuroscience Nicotinic Receptors Meeting II 2009 (Cycle 18) $5,000
Nicotine Dependence Special Projects

Chronic nicotine treatment in primates; role of a6b2 nAChRs 2008 (Cycle 17) $382,500
Nicotine Dependence Research Project Awards
Publications

Differential alterations in nicotinic receptor apha6 and beta3 subunit mRNAs in monkey substantia nigra after nigrostriatal degeneration
Periodical: Neuroscience Index Medicus:
Authors: Quik M, Polonskaya Y, Gillespie A, Lloyd GK, Langston JW ART
Yr: 2000 Vol: 100 Nbr: Abs: Pg: 63-72

Localization of nicotinic receptor subunit mRNAs in monkey brain by in situ hybridization
Periodical: Journal of Comparative Neurology Index Medicus:
Authors: Quik M, Polonskaya Y, Gillespie A, Jankowec M, Lloyd GK, Langston JW ART
Yr: 2000 Vol: 425 Nbr: Abs: Pg: 58-69

Vulnerability of I-conotoxin MII sites to nigrostriatal damage in monkey
Periodical: Journal of Neuroscience Index Medicus:
Authors: Quik M, Polonskaya Y, Kulak J, McIntosh JM ART
Yr: 2001 Vol: 21 Nbr: Abs: Pg: 5494 - 5500

Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits.
Periodical: Pharmacological Reviews Index Medicus:
Authors: Lukas RJ, Changeux JP, Le Novere N, et al. ART
Yr: 1999 Vol: 51 Nbr: Abs: Pg: 397 - 401

Nicotinic receptors and parkinson's disease
Periodical: European Journal of Pharmacology Index Medicus:
Authors: Quik M, and Jeyarasasingam G ART
Yr: 2000 Vol: 393 Nbr: Abs: Pg: 223 - 230

Loss of nicotinic receptors in monkey striatum after MPTP treatment is due to a decline in alpha-conotoxin MII sites.
Periodical: Molecular Pharmacology Index Medicus:
Authors: Kulak JM, McIntosh JM, and Quik M ART
Yr: 2002 Vol: 61 Nbr: Abs: Pg: 230 - 238

Differential nicotinic receptor expression in monkey basal ganglia; effects of nigrostriatal damage.
Periodical: Neuroscience Index Medicus:
Authors: Quik M, Polonskaya Y, McIntosh JM, and Kulak JM ART
Yr: 2002 Vol: 112 Nbr: Abs: Pg: 619 - 630

Iodo-A-85380 binds to alpha-conotoxin MII-sensitive nicotinic receptors as well as alpha4beta2 subtypes.
Periodical: Journal of Neurochemistry Index Medicus:
Authors: Kulak JM, Sum J, Musachio JL, McIntosh JM, and Quik M ART
Yr: 2002 Vol: 81 Nbr: Abs: Pg: 403 - 406

Nicotine and nicotinic receptors; relevance to parkinson's disease.
Periodical: Neurotoxicology Index Medicus:
Authors: Quik M, and Kulak JM ART
Yr: 2002 Vol: 131 Nbr: Abs: Pg: 1 - 14

Declines in differenct beta2 containi8ng nicotinic receptor populations in monkey striatum after nigrostriatal damage.
Periodical: Journal of Pharmacology and Experimental Therapeutics Index Medicus:
Authors: Kulak JM, Musachio JL, McIntosh JM, and Quik M ART
Yr: 0 Vol: Nbr: Abs: Pg:

Differential alterations in nicotinic receptor apha6 and beta3 subunit mRNAs in monkey substantia nigra after nigrostriatal degeneration
Periodical: Neuroscience Index Medicus:
Authors: Quik M, Polonskaya Y, Gillespie A, Lloyd GK, Langston JW ART
Yr: 2000 Vol: 100 Nbr: Abs: Pg: 63-72

Localization of nicotinic receptor subunit mRNAs in monkey brain by in situ hybridization
Periodical: Journal of Comparative Neurology Index Medicus:
Authors: Quik M, Polonskaya Y, Gillespie A, Jankowec M, Lloyd GK, Langston JW ART
Yr: 2000 Vol: 425 Nbr: Abs: Pg: 58-69

Vulnerability of I-conotoxin MII sites to nigrostriatal damage in monkey
Periodical: Journal of Neuroscience Index Medicus:
Authors: Quik M, Polonskaya Y, Kulak J, McIntosh JM ART
Yr: 2001 Vol: 21 Nbr: Abs: Pg: 5494 - 5500

Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits.
Periodical: Pharmacological Reviews Index Medicus:
Authors: Lukas RJ, Changeux JP, Le Novere N, et al. ART
Yr: 1999 Vol: 51 Nbr: Abs: Pg: 397 - 401

Nicotinic receptors and parkinson's disease
Periodical: European Journal of Pharmacology Index Medicus:
Authors: Quik M, and Jeyarasasingam G ART
Yr: 2000 Vol: 393 Nbr: Abs: Pg: 223 - 230

Loss of nicotinic receptors in monkey striatum after MPTP treatment is due to a decline in alpha-conotoxin MII sites.
Periodical: Molecular Pharmacology Index Medicus:
Authors: Kulak JM, McIntosh JM, and Quik M ART
Yr: 2002 Vol: 61 Nbr: Abs: Pg: 230 - 238

Differential nicotinic receptor expression in monkey basal ganglia; effects of nigrostriatal damage.
Periodical: Neuroscience Index Medicus:
Authors: Quik M, Polonskaya Y, McIntosh JM, and Kulak JM ART
Yr: 2002 Vol: 112 Nbr: Abs: Pg: 619 - 630

Iodo-A-85380 binds to alpha-conotoxin MII-sensitive nicotinic receptors as well as alpha4beta2 subtypes.
Periodical: Journal of Neurochemistry Index Medicus:
Authors: Kulak JM, Sum J, Musachio JL, McIntosh JM, and Quik M ART
Yr: 2002 Vol: 81 Nbr: Abs: Pg: 403 - 406

Nicotine and nicotinic receptors; relevance to parkinson's disease.
Periodical: Neurotoxicology Index Medicus:
Authors: Quik M, and Kulak JM ART
Yr: 2002 Vol: 131 Nbr: Abs: Pg: 1 - 14

Declines in differenct beta2 containi8ng nicotinic receptor populations in monkey striatum after nigrostriatal damage.
Periodical: Journal of Pharmacology and Experimental Therapeutics Index Medicus:
Authors: Kulak JM, Musachio JL, McIntosh JM, and Quik M ART
Yr: 0 Vol: Nbr: Abs: Pg:

Nicotine administration reduces striatal MPP+ levels in mice.
Periodical: Brain Research Index Medicus:
Authors: Quik M and Mi Monte DA ART
Yr: 2001 Vol: 917 Nbr: Abs: Pg: 219-224

Stimulation of non-alpha7 nicotinic receptors partially protects dopaminergic neurons of MPP+ induced toxicity in culture.
Periodical: Neuroscience Index Medicus:
Authors: Jeyarasasingam G, Tompkins L, and Quck M ART
Yr: 2002 Vol: 109 Nbr: Abs: Pg: 275-285

Nicotine and nicotinic receptors; relevance to parkinson's disease.
Periodical: Index Medicus:
Authors: Quik M and Kulak JM ART
Yr: Vol: Nbr: Abs: Pg:

Nicotinic receptors and Parkinson's disease
Periodical: European Journal of Pharmacology Index Medicus:
Authors: Quik M, Jeyarasasingam G ART
Yr: 2000 Vol: 393 Nbr: Abs: Pg: 223-230

Differential nicotinic receptor expression in monkey basal ganglia; effects of nigrostriatal damage
Periodical: Neuroscience Index Medicus:
Authors: Quik M, Polonskaya Y, McIntosh JM, Kulak JM ART
Yr: 2002 Vol: 112 Nbr: Abs: Pg: 619-630

Nicotine and nicotinic receptors; relevance to Parkinson's disease
Periodical: Neurotoxicology Index Medicus:
Authors: Quik M, Kulak JM ART
Yr: 2002 Vol: 131 Nbr: Abs: Pg: 581-594

Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice.
Periodical: Molecular Pharmacology Index Medicus:
Authors: Quik M, Sum JD, Whiteaker P, McCallum SE, Marks MJ, Musachio JM, McIntosh JM, et al. ART
Yr: 2003 Vol: 63 Nbr: Abs: Pg: 1169-1179

L-Dopa Treatment Modulates NIcotinic Receptors in Monkey Striatum
Periodical: Molecular Pharmacology Index Medicus:
Authors: Quik M, Bordia T, Fan H, Marks MJ, McIntosh JM, Whiteaker P ART
Yr: 0 Vol: Nbr: Abs: Pg:

Nicotine administration reduces striatal MPP+ levels in mice.
Periodical: Brain Research Index Medicus:
Authors: Quik M and Mi Monte DA ART
Yr: 2001 Vol: 917 Nbr: Abs: Pg: 219-224

Stimulation of non-alpha7 nicotinic receptors partially protects dopaminergic neurons of MPP+ induced toxicity in culture.
Periodical: Neuroscience Index Medicus:
Authors: Jeyarasasingam G, Tompkins L, and Quck M ART
Yr: 2002 Vol: 109 Nbr: Abs: Pg: 275-285

Nicotine and nicotinic receptors; relevance to parkinson's disease.
Periodical: Index Medicus:
Authors: Quik M and Kulak JM ART
Yr: Vol: Nbr: Abs: Pg:

Nicotinic receptors and Parkinson's disease
Periodical: European Journal of Pharmacology Index Medicus:
Authors: Quik M, Jeyarasasingam G ART
Yr: 2000 Vol: 393 Nbr: Abs: Pg: 223-230

Differential nicotinic receptor expression in monkey basal ganglia; effects of nigrostriatal damage
Periodical: Neuroscience Index Medicus:
Authors: Quik M, Polonskaya Y, McIntosh JM, Kulak JM ART
Yr: 2002 Vol: 112 Nbr: Abs: Pg: 619-630

Nicotine and nicotinic receptors; relevance to Parkinson's disease
Periodical: Neurotoxicology Index Medicus:
Authors: Quik M, Kulak JM ART
Yr: 2002 Vol: 131 Nbr: Abs: Pg: 581-594

Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice.
Periodical: Molecular Pharmacology Index Medicus:
Authors: Quik M, Sum JD, Whiteaker P, McCallum SE, Marks MJ, Musachio JM, McIntosh JM, et al. ART
Yr: 2003 Vol: 63 Nbr: Abs: Pg: 1169-1179

L-Dopa Treatment Modulates NIcotinic Receptors in Monkey Striatum
Periodical: Molecular Pharmacology Index Medicus:
Authors: Quik M, Bordia T, Fan H, Marks MJ, McIntosh JM, Whiteaker P ART
Yr: 0 Vol: Nbr: Abs: Pg:

Declines in different beta-2* containing nicotinic receptor populations in monkey striatum after nigrostriatal damage.
Periodical: Journal of Pharmacology and Experimental Therapeutics Index Medicus:
Authors: Kulak JM, Musachio JL, McIntosh JM, Quik M ART
Yr: 2002 Vol: 303 Nbr: Abs: Pg: 633-639

Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice.
Periodical: Molecular Pharmacology Index Medicus:
Authors: Quik M, Sum JD, Whiteaker P, McCallum SE, Marks MJ, Musachio JM, McIntosh JM, et al. ART
Yr: 2003 Vol: 63 Nbr: Abs: Pg: 1169-1179

L-Dopa treatment modulates nicotinic receptors in monkey striatum.
Periodical: Molecular Pharmacology Index Medicus:
Authors: Quik M, Bordia T, Okihara M, Fan H, Marks MJ, McIntosh JM, Whiteaker P ART
Yr: 2003 Vol: 64 Nbr: Abs: Pg: 619-628

Loss of alpha-conotoxin MII- and A85380-sensitive nicotinic receptors in Parkinson's disease striatum.
Periodical: Journal of Neurochemistry Index Medicus:
Authors: Quik M, Bordia T, Forno L, McIntosh JM ART
Yr: 2004 Vol: 88 Nbr: Abs: Pg: 668-679

I-alpha-conotoxinMII nicotinic receptors after nigrostriatal damage in monkeys.
Periodical: Neuroscience Index Medicus:
Authors: Quik M ART
Yr: 2004 Vol: Nbr: Abs: Pg:

Smoking, nicotine and Parkinson's disease
Periodical: Trends in Neuroscience Index Medicus:
Authors: Qwik M ART
Yr: 2004 Vol: 27 Nbr: Abs: Pg: 561 - 568

Selective recovery of striatal 1-alpha-conotoxinMII nicotinic receptors after nigrostriatal damage in monkeys.
Periodical: Neuroscience Index Medicus:
Authors: Lai A, Sum J, Fan H, McIntosh MJ, Quik M ART
Yr: 2004 Vol: 127 Nbr: Abs: Pg: 399 - 408

Subunit composition of nicotinic receptors in monkey striatum; effect of MPTP and L-dopa treatments.
Periodical: Molecular Pharmacology Index Medicus:
Authors: Quik M, Vailati S, Bordia T, Kulak JM, Fan H, McIntosh JM Clementi F, Cotti C ART
Yr: 2005 Vol: 67 Nbr: Abs: Pg: 32 - 41

Decrease in a3*/a6* nicotinic receptors but not nicotine-evoked dopamine release in monkey brain after nigrostrialtal damage.
Periodical: Molecular Pharmacology Index Medicus:
Authors: McCallum SE, Parameswaran N, Bordia T, McIntosh JM, Grady SR, Quik M ART
Yr: 0 Vol: Nbr: Abs: Pg:

Declines in different beta-2* containing nicotinic receptor populations in monkey striatum after nigrostriatal damage.
Periodical: Journal of Pharmacology and Experimental Therapeutics Index Medicus:
Authors: Kulak JM, Musachio JL, McIntosh JM, Quik M ART
Yr: 2002 Vol: 303 Nbr: Abs: Pg: 633-639

Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice.
Periodical: Molecular Pharmacology Index Medicus:
Authors: Quik M, Sum JD, Whiteaker P, McCallum SE, Marks MJ, Musachio JM, McIntosh JM, et al. ART
Yr: 2003 Vol: 63 Nbr: Abs: Pg: 1169-1179

L-Dopa treatment modulates nicotinic receptors in monkey striatum.
Periodical: Molecular Pharmacology Index Medicus:
Authors: Quik M, Bordia T, Okihara M, Fan H, Marks MJ, McIntosh JM, Whiteaker P ART
Yr: 2003 Vol: 64 Nbr: Abs: Pg: 619-628

Loss of alpha-conotoxin MII- and A85380-sensitive nicotinic receptors in Parkinson's disease striatum.
Periodical: Journal of Neurochemistry Index Medicus:
Authors: Quik M, Bordia T, Forno L, McIntosh JM ART
Yr: 2004 Vol: 88 Nbr: Abs: Pg: 668-679

I-alpha-conotoxinMII nicotinic receptors after nigrostriatal damage in monkeys.
Periodical: Neuroscience Index Medicus:
Authors: Quik M ART
Yr: 2004 Vol: Nbr: Abs: Pg:

Smoking, nicotine and Parkinson's disease
Periodical: Trends in Neuroscience Index Medicus:
Authors: Qwik M ART
Yr: 2004 Vol: 27 Nbr: Abs: Pg: 561 - 568

Selective recovery of striatal 1-alpha-conotoxinMII nicotinic receptors after nigrostriatal damage in monkeys.
Periodical: Neuroscience Index Medicus:
Authors: Lai A, Sum J, Fan H, McIntosh MJ, Quik M ART
Yr: 2004 Vol: 127 Nbr: Abs: Pg: 399 - 408

Subunit composition of nicotinic receptors in monkey striatum; effect of MPTP and L-dopa treatments.
Periodical: Molecular Pharmacology Index Medicus:
Authors: Quik M, Vailati S, Bordia T, Kulak JM, Fan H, McIntosh JM Clementi F, Cotti C ART
Yr: 2005 Vol: 67 Nbr: Abs: Pg: 32 - 41

Decrease in a3*/a6* nicotinic receptors but not nicotine-evoked dopamine release in monkey brain after nigrostrialtal damage.
Periodical: Molecular Pharmacology Index Medicus:
Authors: McCallum SE, Parameswaran N, Bordia T, McIntosh JM, Grady SR, Quik M ART
Yr: 0 Vol: Nbr: Abs: Pg:

Prominent role of a3/a6B2* nAChRs in regulating evoked dopamine release in primate putamen; effect of long-term nicotine treatment.
Periodical: Molecular Pharmacology Index Medicus:
Authors: Perez, X; O'Leary, K; Parameswaran, N; McIntosh, JM; Quik, M ART
Yr: 2009 Vol: Nbr: 75 Abs: Pg: 938-946

Prominent role of a3/a6B2* nAChRs in regulating evoked dopamine release in primate putamen; effect of long-term nicotine treatment.
Periodical: Molecular Pharmacology Index Medicus:
Authors: Perez, X; O'Leary, K; Parameswaran, N; McIntosh, JM; Quik, M ART
Yr: 2009 Vol: Nbr: 75 Abs: Pg: 938-946