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Yi Chen, Ph.D.

University of California, San Diego # of Grants: 1

Grants

Dissecting signaling pathways to test cancer-killing agents 1998 (Cycle 7) $69,694
Cancer Postdoctoral Fellowship Awards
Publications

Positive and negative regulation of I kappa B kinase activity through IKK beta subunit phosphorylation
Periodical: Science Index Medicus:
Authors: Delhase M, Hayakawa M, Chen Y, Karin M ART
Yr: 1999 Vol: 284 Nbr: Abs: Pg: 309-313

Inhibition of NF- (kappa) B activation by arsenite through reaction with a critical cysteine in the activation loop of I (kappa) B Kinase.
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Kapahi P, Takahashi T, Natoli G, Adams SR, Chen Y, Tsien RY, and Karin M ART
Yr: 2000 Vol: Nbr: Abs: Pg:

NAK is an ikappaB kinase-activating kinase.
Periodical: Nature Index Medicus:
Authors: Tojima Y, Fujimoto A, Delhase M, Chen Y, Hatakeyama S, et al ART
Yr: 2000 Vol: 404 Nbr: 6779 Abs: Pg: 778-782

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of ikappaB kinase.
Periodical: Nature Index Medicus:
Authors: Rossi A, Kapahi P, Natoli G, Takahashi T, Chen Y, Karin M, and Santoro MG ART
Yr: 2000 Vol: 403 Nbr: 6765 Abs: Pg: 103-108

JNK2 and IKKbeta are required for activating the innate response to viral infection.
Periodical: Immunity Index Medicus:
Authors: Chu WM, Ostertag D, Li ZW, Chang L, Chen Y, Hu Y, Williams B, Perrault J, and Karin M ART
Yr: 1999 Vol: 11 Nbr: 6 Abs: Pg: 721-731