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Ian de Belle, Ph.D.

The Burnham Institute for Medical Research # of Grants: 1

Grants

To identify Egr-1 target genes important in pulmonary diseas 2000 (Cycle 9) $430,539
Pulmonary Disease New Investigator Awards
Publications

The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling.
Periodical: Nature Cell Biology Index Medicus:
Authors: Virolle T, Adamson ED, Baron V, Birle D, Mercola D, Mustelin T, and de Belle I ART
Yr: 2001 Vol: Nbr: Abs: Pg:

In vivo cloning and characterization of a new growth suppressor protein TOE1 as a direct target gene of Egr-1
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: de Belle I, Wu J-X, Sperandio S, Mercola D, Adamson ED ART
Yr: 2003 Vol: 278 Nbr: Abs: Pg: 14306-14312

PTEN is directly transactivated in vivo by Egr-1 during irradiation-induced signalling.
Periodical: Nature Cell Biology Index Medicus:
Authors: Virolle T, Adamson ED, de Belle I, Baron D, Birle D, Mercola T, ART
Yr: 2001 Vol: 3 Nbr: Abs: Pg: 1124 - 1128

Egrl signaling in prostate cancer.
Periodical: Cancer Biology and Therapy Index Medicus:
Authors: Adamson ED, de Belle I, Mittal S, Wang Y, Hayakawa K et al ART
Yr: 2003 Vol: 2 Nbr: Abs: Pg: 610 - 616

Co-activating factors p300 and CBP and transcriptionally cross-regulated by Egrl in prostate cells, leading to divergent responses.
Periodical: Molecular Cell Index Medicus:
Authors: Yu J, de Belle I, Liang H, Adamson ED ART
Yr: 2004 Vol: 15 Nbr: Abs: Pg: 83 - 94