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Darwin Berg, Ph.D.

University of California, San Diego # of Grants: 7

Grants

Nicotine toxicity acting on cardiac neurons 1997 (Cycle 6) $446,920
Nicotine Dependence Research Project Awards

Nicotine Addiction: Novel ACh Receptors on Neurons 1993 (Cycle 2) $369,025
Nicotine Dependence Research Project Awards

Nicotine in the Brain 2000 (Cycle 9) $518,966
Nicotine Dependence Research Project Awards

Nicotinic Manipulation of the Hippocampus 2007 (Cycle 16) $420,000
Nicotine Dependence Research Project Awards

Using Adultborn Neurons to Combat Nicotine Relapse 2010 (Cycle 19) $250,000
Nicotine Dependence Exploratory/Developmental Award

MicroRNA Therapeutics for Nicotine Addiction 2013 (Cycle 22) $250,000
Disparities /Prevention/ Cessation/ Nicotine Dependence Exploratory/Developmental Award

Early Nicotine Exposure Re-Wires Neural Circuits 2016 (Cycle 25) $299,387
Neuroscience of Nicotine Addiction and Treatment High Impact Pilot Award
Publications

Regulation of acetylcholine receptors on chick ciliary ganglion neurons by components from the synaptic target tissue
Periodical: Journal of Neuroscience Index Medicus:
Authors: Halvorsen SW, Schmid HA, McEachern AE, Berg DK ART
Yr: 1991 Vol: 11 Nbr: 7 Abs: Pg: 2177-2186

Nicotinic acetylcholine receptor mRNA in dorsal root ganglion neurons
Periodical: Journal of Neurobiology Index Medicus:
Authors: Boyd RT, Jacob MH, McEachern AE, Caron S, Berg DK ART
Yr: 1991 Vol: 22 Nbr: 1 Abs: Pg: 1-14

Nicotinic receptors that bind alpha-bungaratoxin on neurons raise intracellular free Ca++
Periodical: Neuron Index Medicus:
Authors: Vijayaraghavan S, Pugh PC, Zhang ZW, Rathouz MM, Berg DK ART
Yr: 1992 Vol: 8 Nbr: 2 Abs: Pg: 353-362

The alpha5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain
Periodical: Neuron Index Medicus:
Authors: Conroy WG, Vernallis AB, Berg DK ART
Yr: 1992 Vol: 9 Nbr: 4 Abs: Pg: 679-691

Neurons assemble acetylcholine receptors with as many as three kinds of subunits while maintaining subunit segregation among receptor subtypes
Periodical: Neuron Index Medicus:
Authors: Vernallis AB, Conroy WG, Berg DK ART
Yr: 1993 Vol: 10 Nbr: 3 Abs: Pg: 451-464

Co-expression of multiple acetylcholine receptor genes in neurons: quantification of transcripts during development
Periodical: Journal of Neuroscience Index Medicus:
Authors: Corriveau RA, Berg DK ART
Yr: 1993 Vol: 13 Nbr: 6 Abs: Pg: 2662-2671

Cyclic AMP and the nicotinic response of bovine adrenal chromaffin cells
Periodical: Brain Research Index Medicus:
Authors: Dubin AE, Rathouz MM, Mapp KS, Berg DK ART
Yr: 1992 Vol: 586 Nbr: 2 Abs: Pg: 344-347

Serotinin modulates nicotinic responses of adrenal chromaffin cells
Periodical: Journal of Neurochemistry Index Medicus:
Authors: Vijayaraghavan S, Schmid HA, Mapp KS ART
Yr: 1993 Vol: 61 Nbr: 1 Abs: Pg: 324-331

Inhibition of the nicotinic acetylcholine response by serotonergic and muscarinic agents in chick ciliary ganglion neurones
Periodical: Index Medicus:
Authors: Schmid HA, Vijayaraghavan S ART
Yr: 1992 Vol: 31 Nbr: Abs: Pg: 1001-1008

Neuronal acetylcholine receptors that bind alpha-bungarotoxin mediate neurite retraction in a calcium-dependent manner
Periodical: Journal of Neuroscience Index Medicus:
Authors: Pugh PC, Berk DK ART
Yr: 1994 Vol: 14 Nbr: 2 Abs: Pg: 889-896

Neuronal acetylcholine receptors that bind alpha-bungarotoxin with high affinity function as ligand-gated ion channels
Periodical: Neuron Index Medicus:
Authors: Zhang Z-w, Vijayaraghava S, Berk DK ART
Yr: 1994 Vol: 12 Nbr: 1 Abs: Pg: 167-177

Synaptic-type acetylcholine receptors raise intracellular calcium levels in neurons by two mechanisms
Periodical: Journal of Neuroscience Index Medicus:
Authors: Rathouz MM, Berg DK ART
Yr: 1994 Vol: Nbr: Abs: Pg:

Neurons in culture maintain acetylcholine receptor levels with far fewer transcripts than in vivo
Periodical: Journal of Neurobiology Index Medicus:
Authors: Corriveau RA, Berk DK ART
Yr: 1994 Vol: Nbr: Abs: Pg:

Nicotinic receptor subtypes in the developing chick brain: appearance of a species containing the alpha 4, beta 2, and alpha 5 gene products.
Periodical: Molecular Pharmacology Index Medicus:
Authors: Conroy WG, Berg DK ART
Yr: 1998 Vol: 53 Nbr: Abs: Pg: 392-401

Organizing effects of rapsyn on neuronal nicotinicacetylcholine receptors
Periodical: Molecular and Cellular Neuroscience Index Medicus:
Authors: Kassner PD, Conroy WG, Berg DK ART
Yr: 1998 Vol: Nbr: Abs: Pg:

Targeting alpha7-containing nicotinic receptors on neurons to distal locations
Periodical: European Journal of Pharmacology Index Medicus:
Authors: Roth AL, Shoop RD, Berg DK ART
Yr: 2000 Vol: 393 Nbr: Abs: Pg: 105-112

Two distinct classes of functional alpha7-containing nicotinic receptors on rat superior cervical ganglion neurons
Periodical: Journal of Physiology Index Medicus:
Authors: Cuevas J, Roth AL, Berg DK ART
Yr: 2000 Vol: 525 Nbr: Abs: Pg: 735-746

Cytoskeletal links of neuronal acetylcholine receptors containing alpha7 subunits
Periodical: Journal of Neuroscience Index Medicus:
Authors: Shoop RD, Yamada N, Berg DK ART
Yr: 2000 Vol: 20 Nbr: Abs: Pg: 4021-4029

The neurofilament infrastructure of a developing presynaptic calyx
Periodical: Journal of Comparative Neurology Index Medicus:
Authors: Paysan J, Coggan JS, Conroy WG, Berg DK ART
Yr: 2000 Vol: 425 Nbr: Abs: Pg: 284-294

Cluster formation of alpha7-containing nicotinic receptors at interneuronal interfaces in cell cultures
Periodical: Neuropharmacology Index Medicus:
Authors: Conroy WG, Ogden LF, Berg DK ART
Yr: 2000 Vol: 39 Nbr: Abs: Pg: 2699-2705

Synaptically-driven calcium transients via nicotinic receptors on somatic spines
Periodical: Journal of Neuroscience Index Medicus:
Authors: Shoop RD, Chang KT, Ellisman MH, Berg DK ART
Yr: 2001 Vol: 21 Nbr: Abs: Pg: 771-781

Beta-amyloid peptide blocks the response of alpha7-containing nicotinic receptors on hippocampal neurons
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Liu Q-s, Kawai H, Berg DK ART
Yr: 2001 Vol: 98 Nbr: Abs: Pg: 4734-4739

Nicotinic acetylcholine receptors containing alpha-7 subunits do not undergo long-lasting inactivation even when up-regulated by chronic nicotine exposure.
Periodical: Journal of Neurochemistry Index Medicus:
Authors: Kawai H, Berg DK ART
Yr: 2001 Vol: 78 Nbr: Abs: Pg: 1367-1378

Beta-amyloid peptide blocks the response of alpha-7-containing nicotinic receptors on hippocampal neurons.
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Liu Q, Kawai H, Berg DK ART
Yr: 2001 Vol: 98 Nbr: Abs: Pg: 4734-4739

Voltage-gated channels block nicotinic regulation of CREB phosphorylation and gene expression in neurons.
Periodical: Neuron Index Medicus:
Authors: Chang K, Berg DK ART
Yr: 2001 Vol: 32 Nbr: Abs: Pg: 855-865

Ultrastructure of a somatic spine mat for nicotinic signaling in neurons.
Periodical: Journal of Neuroscience Index Medicus:
Authors: Shoop RD, Esquenazi E, Yamada N, Ellisman MH, Berg DK ART
Yr: 2002 Vol: 22 Nbr: Abs: Pg: 748-756

Nicotinic alpha-7 receptors: synaptic options and down-stream signaling in neurons.
Periodical: Journal of Neuroscience Index Medicus:
Authors: Berg DK, Conroy WG ART
Yr: 2002 Vol: 53 Nbr: Abs: Pg: 512-523

Maturation of postsynaptic nicotinic structures on autonomic neurons requires innervation but not cholinergic transmission.
Periodical: European Journal of Neuroscience Index Medicus:
Authors: Kaiser S, Blank M, Berg DK ART
Yr: 2002 Vol: 16 Nbr: Abs: Pg: 1-10

Nicotinic alpha-7 receptor clusters on hippocampal GABAergic neurons: regulation by synaptic activity and neurotrophins.
Periodical: Journal of Neuroscience Index Medicus:
Authors: Kawai H, Zago W, Berg DK ART
Yr: 2002 Vol: 22 Nbr: Abs: Pg: 7903-7912

Nicotinic regulation of CREB activation in hippocampal neurons by glutamatergic and non0glutamatergic pathways.
Periodical: Molecular Cell Neuroscience Index Medicus:
Authors: Hu M, Liu Qs, Chang KT, Berg DK ART
Yr: 2002 Vol: 21 Nbr: Abs: Pg: 616-625

Potentiation of alpha-7-containing nicotinic acetylcholine receptors by select albumins
Periodical: Index Medicus:
Authors: Conroy WG, Liu Qs, Nai Q, Margiotta JF, Berg DK ART
Yr: Vol: Nbr: Abs: Pg:

PDZ-containing proteins provide a functional postsynaptic scaffold for nicotinic receptors in neurons.
Periodical: Neuron Index Medicus:
Authors: Conroy WG, Liu Z, Nai Q, Coggan JS, Berg DK ART
Yr: 2003 Vol: 38 Nbr: Abs: Pg: 759-771

Large clusters of alpha-7-containing nicotinic acetylcholine receptors on chick spinal cord neurons.
Periodical: Journal of Comparative Neurology Index Medicus:
Authors: Roth AL, Berg DK ART
Yr: 2003 Vol: Nbr: Abs: Pg:

Multiple cell adhesion molecules shaping a complex nicotinic synapse on neurons.
Periodical: Molecular and Cellular Neuroscience Index Medicus:
Authors: Triana-Baltzer, GB; Lui, Z; Gounko, NV; and Berg, DK ART
Yr: 2008 Vol: Nbr: 39 Abs: Pg: 74-82

Silent synapses sit and wait for a better day.
Periodical: Neuron Index Medicus:
Authors: Berg, DK ART
Yr: 2009 Vol: Nbr: 61 Abs: Pg: 157-159

Postsynaptic scaffolds for nicotinic receptors on neurons.
Periodical: Acta Pharmacol Sin Index Medicus:
Authors: Nef, RA; Gomez-Varela, D; Fernandes, CC; and Berg, DK ART
Yr: 2009 Vol: Nbr: Abs: Pg:

PMCA2 via PSD-95 controls signaling by á7-containing nicotinic acetylcholine receptors on aspiny neurons
Periodical: Journal of Neuroscience Index Medicus:
Authors: Gomez-Varela D, Schmidt M, Schoellerman J, Peters E, Berg DK ART
Yr: 2012 Vol: Nbr: 32 Abs: Pg: 6894-6905

Glutamatergic synapse formation is promoted by á7-containing nicotinic acetylcholine receptors.
Periodical: Journal of Neuroscience Index Medicus:
Authors: Lozada AF, Wang X, Gounko NV, Massey KA, Duan J, Liu Z, Berg DK ART
Yr: 2012 Vol: Nbr: 32 Abs: Pg: 7651-7661

Induction of dendritic spines by B2-containing nicotinic receptors
Periodical: Journal of Neuroscience Index Medicus:
Authors: Lozada AF, Wang X, Gounko NV, Massey KA, Duan J, Liu Z, Berg DK ART
Yr: 2012 Vol: Nbr: 32 Abs: Pg: 8391-8400

Nicotinic control of adult-born neuron fate
Periodical: Biochemical Pharmacology Index Medicus:
Authors: Campbell NR, Fernandes CC, John D, Lozada AF, Berg, DK ART
Yr: 2011 Vol: Nbr: 82 Abs: Pg: 820-827

A novel mechanism for nicotinic potentiation of glutamatergic synapses
Periodical: Index Medicus:
Authors: Halff AW, Gomez-Varela D, John D, Berg DK ART
Yr: Vol: Nbr: Abs: Pg:

Nicotine recruits glutamate receptors to postsynaptic sites
Periodical: Index Medicus:
Authors: Duan JJ, Lozada AF, Gou CY, Xu J, Chen Y, Berg DK ART
Yr: Vol: Nbr: Abs: Pg:

Long-lasting changes in neural networks to compensate for altered nicotinic input
Periodical: Index Medicus:
Authors: John D, Berg DK ART
Yr: Vol: Nbr: Abs: Pg: