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Tzipora Goldkorn, BSc, MSc, Ph.D.

University of California, Davis # of Grants: 3

Grants

Tobacco oxidants and the ceramide path in lung cell death 1999 (Cycle 8) $427,613
Pulmonary Disease Research Project Awards

Cigarette smoke injures lung epithelium by activating nSMase 2008 (Cycle 17) $394,380
Pulmonary Disease Research Project Awards

Joint roles of ceramide, EGFR/Src in lung injury and cancer 2013 (Cycle 22) $467,606
Early Diagnosis/Pathogenesis Research Project Awards
Publications

Ceramide path in human lung cell death
Periodical: American Journal of Respiratory Cell and Molecular Biology Index Medicus:
Authors: Chan C, Goldkorn T ART
Yr: 2000 Vol: 22 Nbr: 4 Abs: Pg: 460-468

Role of ceramide in activation of cas 3 during apoptosis of A549 lung epithelial cells.
Periodical: Index Medicus:
Authors: Ravid T, Tsaba A, Rasooly R, Lavrentiadou S, and Goldkorn T ART
Yr: Vol: Nbr: Abs: Pg:

Ceramide-mediated apoptosis in lung epithelial cells is regulated by gluthathione.
Periodical: American Journal of Respiratory Cell and Molecular Biology Index Medicus:
Authors: Lavrentiadou SN, Chan C, Kawcak T, Ravid T, Tsaba A, van der Vliet A, Rasooly R, and et al ART
Yr: 2001 Vol: 25 Nbr: Abs: Pg: 676-684

Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cells.
Periodical: American Journal of Physiology. Lung Cell Molecular Physiology. Index Medicus:
Authors: Ravid T, Tsaba A, Gee P, Rasooly R, Medina EA, Goldkorn T ART
Yr: 2003 Vol: 284 Nbr: 6 Abs: Pg: L1082-1092

Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione.
Periodical: American Journal of Respiratory Cell and Molecular Biology Index Medicus:
Authors: Lavrentiadou S, Chan C, Kawcak T, Ravid T, Tsaba A, van der Vliet A, Rasooly R, Goldkorn T ART
Yr: 2001 Vol: 25 Nbr: Abs: Pg: 676-684

Ceramide path in human lung cell death.
Periodical: American Journal of Respiratory Cell and Molecular Biology Index Medicus:
Authors: Chan C, Goldkorn T ART
Yr: 2000 Vol: 22 Nbr: 4 Abs: Pg: 460-468

H202 acts on cellular membranes to generate ceramide signaling and initiate apoptosis in tracheobronchial epithelial cells.
Periodical: Journal of Cell Science Index Medicus:
Authors: Goldkorn T, Balaban N, Shannon M, Chea V, Matsukuma K, Gilchrist D, Wang H, Chan C ART
Yr: 1998 Vol: 111 Nbr: 21 Abs: Pg: 3209-3220

Neutral sphingomyelinas 2 is activated by cigarette smoke to augment ceramide-induced apoptosis in lung cell death.
Periodical: American Journal of Physiology. Lung Cell Molecular Physiology. Index Medicus:
Authors: Levy M; Khan E; Careaga M; Goldkorn T ART
Yr: 2009 Vol: 297 Nbr: 1 Abs: Pg: L125-133

Neutral sphingomyelinase 2 (nSMase2) is a phosphoprotein regulated by calcineurin (PP2B).
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Filosto, S; Fry, W; Knowlton, AA; Goldkorn, T ART
Yr: 2010 Vol: 285 Nbr: Abs: Pg: 10213-10222

Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress:_x000d_ Molecular mechanisms and therapeutic opportunities involving the ceramide generating machinery and EGF receptor
Periodical: Index Medicus:
Authors: Goldkorn T, Filosto S, Chung S. ART
Yr: Vol: Nbr: Abs: Pg:

Src meidates cigarette smoke-induced resistance to tyrosine kinase inhibitors in NSCLC cells.
Periodical: Index Medicus:
Authors: Filosto S, Baston DS, Chung S, Becker CR, Goldkorn T ART
Yr: Vol: Nbr: Abs: Pg:

Src regulates cigarette smoke-induced ceramide generation via nSmase2 in the airway epithelium
Periodical: Index Medicus:
Authors: Chung S, Vu S, Filosto S, Goldkorn T ART
Yr: Vol: Nbr: Abs: Pg: