Tzipora Goldkorn, BSc, MSc, Ph.D. 
		
		 
       
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          University of California, Davis  
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           # of Grants: 3 | 
        
        
      
      
      
       Grants
      
      
      
      
     
      Publications 
     
            
      
        
          | Ceramide path in human lung cell death | 
        
        
        
          | Periodical: American Journal of Respiratory Cell and Molecular Biology | 
          Index Medicus:  | 
        
        
          | Authors: Chan C, Goldkorn T |  
          ART | 
        
        
          | Yr: 2000 | 
          Vol: 22 | 
          Nbr: 4 | 
          Abs:  | 
          Pg: 460-468 | 
        
      
            
      
        
          | Role of ceramide in activation of cas 3 during apoptosis of A549 lung epithelial cells. | 
        
        
        
          | Periodical:  | 
          Index Medicus:  | 
        
        
          | Authors: Ravid T, Tsaba A, Rasooly R, Lavrentiadou S, and Goldkorn T |  
          ART | 
        
        
          | Yr:  | 
          Vol:  | 
          Nbr:  | 
          Abs:  | 
          Pg:  | 
        
      
            
      
        
          | Ceramide-mediated apoptosis in lung epithelial cells is regulated by gluthathione. | 
        
        
        
          | Periodical: American Journal of Respiratory Cell and Molecular Biology | 
          Index Medicus:  | 
        
        
          | Authors: Lavrentiadou SN, Chan C, Kawcak T, Ravid T, Tsaba A, van der Vliet A, Rasooly R, and et al |  
          ART | 
        
        
          | Yr: 2001 | 
          Vol: 25 | 
          Nbr:  | 
          Abs:  | 
          Pg: 676-684 | 
        
      
            
      
        
          | Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cells. | 
        
        
        
          | Periodical: American Journal of Physiology. Lung Cell Molecular Physiology. | 
          Index Medicus:  | 
        
        
          | Authors: Ravid T, Tsaba A, Gee P, Rasooly R, Medina EA, Goldkorn T |  
          ART | 
        
        
          | Yr: 2003 | 
          Vol: 284 | 
          Nbr: 6 | 
          Abs:  | 
          Pg: L1082-1092 | 
        
      
            
      
        
          | Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione. | 
        
        
        
          | Periodical: American Journal of Respiratory Cell and Molecular Biology | 
          Index Medicus:  | 
        
        
          | Authors: Lavrentiadou S, Chan C, Kawcak T, Ravid T, Tsaba A, van der Vliet A, Rasooly R, Goldkorn T |  
          ART | 
        
        
          | Yr: 2001 | 
          Vol: 25 | 
          Nbr:  | 
          Abs:  | 
          Pg: 676-684 | 
        
      
            
      
        
          | Ceramide path in human lung cell death. | 
        
        
        
          | Periodical: American Journal of Respiratory Cell and Molecular Biology | 
          Index Medicus:  | 
        
        
          | Authors: Chan C, Goldkorn T |  
          ART | 
        
        
          | Yr: 2000 | 
          Vol: 22 | 
          Nbr: 4 | 
          Abs:  | 
          Pg: 460-468 | 
        
      
            
      
        
          | H202 acts on cellular membranes to generate ceramide signaling and initiate apoptosis in tracheobronchial epithelial cells. | 
        
        
        
          | Periodical: Journal of Cell Science | 
          Index Medicus:  | 
        
        
          | Authors: Goldkorn T, Balaban N, Shannon M, Chea V, Matsukuma K, Gilchrist D, Wang H, Chan C |  
          ART | 
        
        
          | Yr: 1998 | 
          Vol: 111 | 
          Nbr: 21 | 
          Abs:  | 
          Pg: 3209-3220 | 
        
      
            
      
        
          | Ceramide path in human lung cell death | 
        
        
        
          | Periodical: American Journal of Respiratory Cell and Molecular Biology | 
          Index Medicus:  | 
        
        
          | Authors: Chan C, Goldkorn T |  
          ART | 
        
        
          | Yr: 2000 | 
          Vol: 22 | 
          Nbr: 4 | 
          Abs:  | 
          Pg: 460-468 | 
        
      
            
      
        
          | Role of ceramide in activation of cas 3 during apoptosis of A549 lung epithelial cells. | 
        
        
        
          | Periodical:  | 
          Index Medicus:  | 
        
        
          | Authors: Ravid T, Tsaba A, Rasooly R, Lavrentiadou S, and Goldkorn T |  
          ART | 
        
        
          | Yr:  | 
          Vol:  | 
          Nbr:  | 
          Abs:  | 
          Pg:  | 
        
      
            
      
        
          | Ceramide-mediated apoptosis in lung epithelial cells is regulated by gluthathione. | 
        
        
        
          | Periodical: American Journal of Respiratory Cell and Molecular Biology | 
          Index Medicus:  | 
        
        
          | Authors: Lavrentiadou SN, Chan C, Kawcak T, Ravid T, Tsaba A, van der Vliet A, Rasooly R, and et al |  
          ART | 
        
        
          | Yr: 2001 | 
          Vol: 25 | 
          Nbr:  | 
          Abs:  | 
          Pg: 676-684 | 
        
      
            
      
        
          | Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cells. | 
        
        
        
          | Periodical: American Journal of Physiology. Lung Cell Molecular Physiology. | 
          Index Medicus:  | 
        
        
          | Authors: Ravid T, Tsaba A, Gee P, Rasooly R, Medina EA, Goldkorn T |  
          ART | 
        
        
          | Yr: 2003 | 
          Vol: 284 | 
          Nbr: 6 | 
          Abs:  | 
          Pg: L1082-1092 | 
        
      
            
      
        
          | Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione. | 
        
        
        
          | Periodical: American Journal of Respiratory Cell and Molecular Biology | 
          Index Medicus:  | 
        
        
          | Authors: Lavrentiadou S, Chan C, Kawcak T, Ravid T, Tsaba A, van der Vliet A, Rasooly R, Goldkorn T |  
          ART | 
        
        
          | Yr: 2001 | 
          Vol: 25 | 
          Nbr:  | 
          Abs:  | 
          Pg: 676-684 | 
        
      
            
      
        
          | Ceramide path in human lung cell death. | 
        
        
        
          | Periodical: American Journal of Respiratory Cell and Molecular Biology | 
          Index Medicus:  | 
        
        
          | Authors: Chan C, Goldkorn T |  
          ART | 
        
        
          | Yr: 2000 | 
          Vol: 22 | 
          Nbr: 4 | 
          Abs:  | 
          Pg: 460-468 | 
        
      
            
      
        
          | H202 acts on cellular membranes to generate ceramide signaling and initiate apoptosis in tracheobronchial epithelial cells. | 
        
        
        
          | Periodical: Journal of Cell Science | 
          Index Medicus:  | 
        
        
          | Authors: Goldkorn T, Balaban N, Shannon M, Chea V, Matsukuma K, Gilchrist D, Wang H, Chan C |  
          ART | 
        
        
          | Yr: 1998 | 
          Vol: 111 | 
          Nbr: 21 | 
          Abs:  | 
          Pg: 3209-3220 | 
        
      
            
      
        
          | Neutral sphingomyelinas 2 is activated by cigarette smoke to augment ceramide-induced apoptosis in lung cell death. | 
        
        
        
          | Periodical: American Journal of Physiology. Lung Cell Molecular Physiology. | 
          Index Medicus:  | 
        
        
          | Authors: Levy M; Khan E; Careaga M; Goldkorn T |  
          ART | 
        
        
          | Yr: 2009 | 
          Vol: 297 | 
          Nbr: 1 | 
          Abs:  | 
          Pg: L125-133 | 
        
      
            
      
        
          | Neutral sphingomyelinase 2 (nSMase2) is a phosphoprotein regulated by calcineurin (PP2B). | 
        
        
        
          | Periodical: Journal of Biological Chemistry | 
          Index Medicus:  | 
        
        
          | Authors: Filosto, S; Fry, W; Knowlton, AA; Goldkorn, T |  
          ART | 
        
        
          | Yr: 2010 | 
          Vol: 285 | 
          Nbr:  | 
          Abs:  | 
          Pg: 10213-10222 | 
        
      
            
      
        
          | Neutral sphingomyelinas 2 is activated by cigarette smoke to augment ceramide-induced apoptosis in lung cell death. | 
        
        
        
          | Periodical: American Journal of Physiology. Lung Cell Molecular Physiology. | 
          Index Medicus:  | 
        
        
          | Authors: Levy M; Khan E; Careaga M; Goldkorn T |  
          ART | 
        
        
          | Yr: 2009 | 
          Vol: 297 | 
          Nbr: 1 | 
          Abs:  | 
          Pg: L125-133 | 
        
      
            
      
        
          | Neutral sphingomyelinase 2 (nSMase2) is a phosphoprotein regulated by calcineurin (PP2B). | 
        
        
        
          | Periodical: Journal of Biological Chemistry | 
          Index Medicus:  | 
        
        
          | Authors: Filosto, S; Fry, W; Knowlton, AA; Goldkorn, T |  
          ART | 
        
        
          | Yr: 2010 | 
          Vol: 285 | 
          Nbr:  | 
          Abs:  | 
          Pg: 10213-10222 | 
        
      
            
      
        
          | Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress:_x000D_
Molecular mechanisms and therapeutic opportunities involving the ceramide generating machinery and EGF receptor | 
        
        
        
          | Periodical: Antioxidants & Redox Signaling | 
          Index Medicus:  | 
        
        
          | Authors: Goldkorn T, Filosto S, Chung S. |  
          ART | 
        
        
          | Yr: 2104 | 
          Vol: 24684526 | 
          Nbr:  | 
          Abs:  | 
          Pg:  | 
        
      
            
      
        
          | Src meidates cigarette smoke-induced resistance to tyrosine kinase inhibitors in NSCLC cells. | 
        
        
        
          | Periodical: Molecular Cancer Therapeutics | 
          Index Medicus:  | 
        
        
          | Authors: Filosto S, Baston DS, Chung S, Becker CR, Goldkorn T |  
          ART | 
        
        
          | Yr: 2013 | 
          Vol:  | 
          Nbr:  | 
          Abs:  | 
          Pg:  | 
        
      
            
      
        
          | Src regulates cigarette smoke-induced ceramide generation via nSmase2 in the airway epithelium | 
        
        
        
          | Periodical: American Journal of Respiratory Cell and Molecular Biology | 
          Index Medicus:  | 
        
        
          | Authors: Chung S, Vu S, Filosto S, Goldkorn T |  
          ART | 
        
        
          | Yr: 2015 | 
          Vol: 52 | 
          Nbr:  | 
          Abs:  | 
          Pg: 738-48 | 
        
      
            
      
        
          | Src mediates cigarette smoke-induced resistance to tyrosine kinase inhibitors in NSCLC cells | 
        
        
        
          | Periodical: Molecular Cancer Therapeutics | 
          Index Medicus:  | 
        
        
          | Authors: Filosto S,_x000D_
Baston DS, Chung S, Becker CR, Goldkorn T |  
          ART | 
        
        
          | Yr: 2017 | 
          Vol: 12 | 
          Nbr: 8 | 
          Abs:  | 
          Pg: 1579-90 | 
        
      
            
      
        
          | Lung cancer and lung injury: the dual role of ceramide | 
        
        
        
          | Periodical: Handbook of Experimental Pharmacology | 
          Index Medicus:  | 
        
        
          | Authors: Goldkorn T, Chung S, Filosto S |  
          ART | 
        
        
          | Yr: 2016 | 
          Vol: 2013 | 
          Nbr: 216 | 
          Abs:  | 
          Pg: 93-113 | 
        
      
            
      
        
          | Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress:_x000D_
Molecular mechanisms and therapeutic opportunities involving the ceramide generating machinery and EGF receptor | 
        
        
        
          | Periodical: Antioxidants & Redox Signaling | 
          Index Medicus:  | 
        
        
          | Authors: Goldkorn T, Filosto S, Chung S. |  
          ART | 
        
        
          | Yr: 2104 | 
          Vol: 24684526 | 
          Nbr:  | 
          Abs:  | 
          Pg:  | 
        
      
            
      
        
          | Src meidates cigarette smoke-induced resistance to tyrosine kinase inhibitors in NSCLC cells. | 
        
        
        
          | Periodical: Molecular Cancer Therapeutics | 
          Index Medicus:  | 
        
        
          | Authors: Filosto S, Baston DS, Chung S, Becker CR, Goldkorn T |  
          ART | 
        
        
          | Yr: 2013 | 
          Vol:  | 
          Nbr:  | 
          Abs:  | 
          Pg:  | 
        
      
            
      
        
          | Src regulates cigarette smoke-induced ceramide generation via nSmase2 in the airway epithelium | 
        
        
        
          | Periodical: American Journal of Respiratory Cell and Molecular Biology | 
          Index Medicus:  | 
        
        
          | Authors: Chung S, Vu S, Filosto S, Goldkorn T |  
          ART | 
        
        
          | Yr: 2015 | 
          Vol: 52 | 
          Nbr:  | 
          Abs:  | 
          Pg: 738-48 | 
        
      
            
      
        
          | Src mediates cigarette smoke-induced resistance to tyrosine kinase inhibitors in NSCLC cells | 
        
        
        
          | Periodical: Molecular Cancer Therapeutics | 
          Index Medicus:  | 
        
        
          | Authors: Filosto S,_x000D_
Baston DS, Chung S, Becker CR, Goldkorn T |  
          ART | 
        
        
          | Yr: 2017 | 
          Vol: 12 | 
          Nbr: 8 | 
          Abs:  | 
          Pg: 1579-90 | 
        
      
            
      
        
          | Lung cancer and lung injury: the dual role of ceramide | 
        
        
        
          | Periodical: Handbook of Experimental Pharmacology | 
          Index Medicus:  | 
        
        
          | Authors: Goldkorn T, Chung S, Filosto S |  
          ART | 
        
        
          | Yr: 2016 | 
          Vol: 2013 | 
          Nbr: 216 | 
          Abs:  | 
          Pg: 93-113 |