Research Portfolio

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Jiing-Dwan Lee, Ph.D.

Scripps Research Institute # of Grants: 2

Grants

Unraveling lung cancer signaling pathways 2006 (Cycle 15) $780,780
Cancer Research Project Awards

Enhancing mTOR-targeted lung cancer therapy 2010 (Cycle 19) $473,879
Cancer Exploratory/Developmental Award
Publications

CDC25B mediates rapamycin-induced oncogenic responses in cancer cells.
Periodical: Cancer Research Index Medicus:
Authors: Chen, RQ; Yang, QK; Lu, BW; Wei, Y; Cantin, G; Chen, YL; Fearns, C; Yates, J, III; Lee, J ART
Yr: 2009 Vol: 69 Nbr: 6 Abs: Pg: 2663-2668

Combined integrin phosphoproteomic analyses and siRNA-based functional screening identified key regulators for cancerl cell adhesion and migration.
Periodical: Cancer Research Index Medicus:
Authors: Chen, Y; Lu, B; Yang, Q; Fearns, C; Yates, J, III; Lee, JD ART
Yr: 2009 Vol: 69 Nbr: 8 Abs: Pg: 3713-3120

Kinome siRNA scteen identifies SMG-1 as a negative regulator of HIF-1alpha in hypoxia.
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Chen, RQ; Yang, QK; Chen, YL; Oliveira, VA; Dalton, WS; Fearns, C; Lee, JD; ART
Yr: 2009 Vol: Nbr: Abs: Pg:

Pharmacological inhibition of BMK1 suppresses tumor growth through PML
Periodical: Cancer Cell Index Medicus:
Authors: Yang, Q; Deng, X; Lu, B; Cameron, M; Fearns, C; Patricelli, M; Yates, J; Gray, N; Lee, J ART
Yr: 2010 Vol: Nbr: Abs: Pg:

BMK1 kinase suppresses epithelial-mesenchymal transition through the Akt/GSK3รข_x000d_ signaling pathway.
Periodical: Cancer Research Index Medicus:
Authors: Chen R, Yang Q, Lee JD. ART
Yr: 2012 Vol: 72 Nbr: (6) Abs: Pg: 1579-87

BMK1 is involved in the regulation of p53 through disrupting the PML-MDM2 interaction
Periodical: Oncogene Index Medicus:
Authors: Yang Q, Liao L, Deng X, Chen R, Gray NS, Yates JR 3rd, Lee JD ART
Yr: 2013 Vol: 32 Nbr: 26 Abs: Pg: 3156-64