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Timothy Bigby, M.D.

University of California, San Diego # of Grants: 1

Grants

Inflammatory compounds:role in tobacco-related lung disease 1998 (Cycle 7) $447,367
Cancer Research Project Awards
Publications

Transforming growth factor beta increases leukotriene C4 synthase expression in the monocyte-like cell line, THP-1
Periodical: Journal of Immunology Index Medicus:
Authors: Riddick CA, Serio KJ, Hodulik DJ, Regan MS, Ring WL, Bigby TD ART
Yr: 1999 Vol: 162 Nbr: Abs: Pg: 1101-1107

Regulation of expression of the 5-lipoxy genase pathway
Periodical: Clinical Reviews in Allergy and Immunology Index Medicus:
Authors: Bigby TD ART
Yr: 1999 Vol: 14 Nbr: Abs: Pg: 43-58

SP1 and Sp3 function as key regulators of leukotriene C4 synthase gene expression in the monocyte-like cell line THP-1
Periodical: American Journal of Respiratory Cell and Molecular Biology Index Medicus:
Authors: Serio KJ, Hodulik CR, Bigby TD ART
Yr: 2000 Vol: 23 Nbr: Abs: Pg: 234-240

Perspective: the leukotriene C4 synthase gene and asthma
Periodical: American Journal of Respiratory Cell and Molecular Biology Index Medicus:
Authors: Bigby TD ART
Yr: 2000 Vol: 23 Nbr: Abs: Pg: 273-276

Regulation of leukotriene C4 synthase gene expression by Sp1 and Sp3 in mononuclear phagocytes
Periodical: American Journal of Respiratory and Critical Care Medicine Index Medicus:
Authors: Serio KJ, Hodulik CR, Bigby TD ART
Yr: 1999 Vol: 159 Nbr: A642 Abs: Pg:

The yin and the yang of 5-lipoxygenase pathway activation
Periodical: Molecular Pharmacology Index Medicus:
Authors: Bigby TD ART
Yr: 2002 Vol: 62 Nbr: Abs: Pg: 200 - 202

A single base pair A to C substitution at - 366 in the promoter region of the LTC4 synthase gene is associated with decreased expression in vitro.
Periodical: American Journal of Respiratory and Critical Care Medicine Index Medicus:
Authors: Jamil SM, Hodulik CR, Serio KJ, and Bigby TD ART
Yr: 2000 Vol: 161 Nbr: A762 Abs: Pg: