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Shi Huang, Ph.D.

The Burnham Institute for Medical Research # of Grants: 1

Grants

Suppressor genes of lung cancer 1998 (Cycle 7) $859,254
Cancer Research Project Awards
Publications

RIZ1 , but not the alternative RIZ2 product of the same gene, is underexpressed in breast cancer and forced RIZ1 expression causes G2/M cell cycle arrest and/or apoptosis
Periodical: Cancer Research Index Medicus:
Authors: He L, Yu J, Liu X, et al ART
Yr: 1999 Vol: 58 Nbr: Abs: Pg: 4238-4244

The yin-yang of PR domain family genes in tumorigenesis
Periodical: Histopathology Index Medicus:
Authors: Jiang G-L, Huang S ART
Yr: 2000 Vol: 15 Nbr: Abs: Pg: 109-117

Decreased RIZ1 expression but not RIZ2 in hepatoma and suppression of hepatoma tumorigenicity by RIZ1
Periodical: International Journal of Cancer Index Medicus:
Authors: Jiang G-L, Liu L, Buyse I, Simon D, Huang S ART
Yr: 1999 Vol: 83 Nbr: Abs: Pg: 541-547

PFM1 (PRDM4), a new member of the PR domain family, maps to a tumor suppressor locus on human chromosome 12q23-q24.1
Periodical: Genomics Index Medicus:
Authors: Yang X-H, Huang S ART
Yr: 1999 Vol: 61 Nbr: Abs: Pg: 319-325

Mapping of a minimal deleted region in human hepatocellular carcinoma to 1p36.13-p36.23 and mutational analysis of the RIZ gene localized to the region
Periodical: Genes Chromosomes Cancer Index Medicus:
Authors: Fang W, Piao Z, Simon D, Sheu J-C, Huang S ART
Yr: 2000 Vol: 28 Nbr: Abs: Pg: 269-275

Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Chadwick RB, Jiang G-L, Bennington GA, et al ART
Yr: 2000 Vol: 97 Nbr: Abs: Pg: 2662-2667

Chromatin becomes hot in cancer pathogenesis and therapy
Periodical: Trends in Genetics Index Medicus:
Authors: Huang S ART
Yr: 2000 Vol: 16 Nbr: Abs: Pg: 200-201

RIZ1 is a tumor suppressor on chromosome band 1p36, a commonly deleted region in human cancers
Periodical: Nature Medicine Index Medicus:
Authors: Steele-Perkins G, Jiang G-L, Fang W, et al ART
Yr: 2000 Vol: Nbr: Abs: Pg:

Involvement of the MKK6-p38 cascade in radiation-induced cell cycle arrest
Periodical: Molecular and Cellular Biology Index Medicus:
Authors: Wang X, McGowan CH, Zhao M, et al ART
Yr: 2000 Vol: 20 Nbr: Abs: Pg: 4543-4552

Frequent frameshift mutations of RIZ in human gastrointestinal and endometrial carcinomas with microsatellite instability
Periodical: Cancer Research Index Medicus:
Authors: Piao Z, Fang W, Malkhosyan S, et al ART
Yr: 2000 Vol: 6 Nbr: Abs: Pg: 4701-4704

RIZ, the retinoblastoma protein interacting zinc finger gene, is mutated in genetically unstable cancers of the pancreas, stomach, and colorectum
Periodical: Genes Chromosomes Cancer Index Medicus:
Authors: Sakurada K, Furukawa T, Kato Y, Kayama T, Huang S, Horii A ART
Yr: 2001 Vol: 30 Nbr: Abs: Pg: 207-211

Preferential loss in human cancer of a polymorphic RIZ allele that is more common in Asians than Caucasians
Periodical: British Journal of Cancer Index Medicus:
Authors: Fang W, Piao Z, Simon D, Sheu J-C, Perucho M, Huang S ART
Yr: 2001 Vol: 84 Nbr: Abs: Pg: 743-747

Adenovirus expressing RIZ1 in tumor suppressor gene therapy of microsatellite-unstable colorectal cancers
Periodical: Cancer Research Index Medicus:
Authors: Jiang G-L, Huang S ART
Yr: 2001 Vol: 61 Nbr: Abs: Pg: 1796-1798

Tumor formation and inactivation of RIZ1, a Rb-binding member of a nuclear protein methyltransferase superfamily
Periodical: Genes and Development Index Medicus:
Authors: Steele-Perkins G, Fang W, Van Gele M, et al ART
Yr: 2001 Vol: 15 Nbr: Abs: Pg: 2250-2262

The PR domain of the rb-binding zinc finger gene R1Z1 is a protein-binding interface and is related to the SET domain functioning in chromatin mediated gene expression.
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Huang S, Shao G, and Liu L ART
Yr: 1998 Vol: 273 Nbr: Abs: Pg: 15933 - 15940

The retinoblastoma-protein interacting zinc finger gene RIZ in lp36-linked cancers.
Periodical: Frontiers in Bioscience Index Medicus:
Authors: Huang S ART
Yr: 1999 Vol: 4 Nbr: Abs: Pg: D528 - D532

Hypermethylation in human cancers of the R1Z1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily.
Periodical: Cancer Research Index Medicus:
Authors: Du Y, Carling T, Fang W, Piao Z, Sheu J-C, and Huang S ART
Yr: 2001 Vol: 22 Nbr: Abs: Pg: 8094 - 8099

The tumor suppressor gene RIZ in cancer gene therapy.
Periodical: Oncology Reports Index Medicus:
Authors: Canote R, Du Y, Carling T, Tian F, Peng Z and Huang S ART
Yr: 2002 Vol: 9 Nbr: Abs: Pg: 57 - 60

Histone methyltransferases, diet nutrients and tumor suppressors.
Periodical: Nature Reviews. Cancer Index Medicus:
Authors: Huang S ART
Yr: 2002 Vol: 2 Nbr: Abs: Pg: 469 - 476