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Stephen Nishimura, M.D.

University of California, San Francisco # of Grants: 2

Grants

Role for fibroblasts in the chronic immune response in COPD 2011 (Cycle 20) $250,000
Pulmonary Disease Exploratory/Developmental Award

Airway inflammation in the evolution of airway fibrosis 2015 (Cycle 24) $421,284
Early Diagnosis/Pathogenesis Research Project Awards
Publications

Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation and fibrosis, through integrin ávâ8-mediated activation of TGF-â
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Hideya Kitamura, Stephanie Cambier, Sangeeta Somanath, Tyren Barker, Shunsuke Minagawa, Je ART
Yr: 2011 Vol: 121 Nbr: 7 Abs: Pg: 2863-75

Interleukin-1{beta} induces increased transcriptional activation of the transforming growth factor-{beta} activating_x000D_ integrin subunit {beta}8 through altering chromatin architecture
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Markovics JA, Araya J, Cambier S, Somanath S, Gline S, Jablons D, Hill A, Wolters PJ, Nish ART
Yr: 2011 Vol: 286 Nbr: 42 Abs: Pg: 36864-74

Selective targeting of TGF-beta activation to treat fibroinflammatory airway disease
Periodical: Science Translational Medicine Index Medicus:
Authors: Minagawa S, Lou J, Seed RI, Cormier A, Wu S, Cheng Y, Murray L, Tsui P, Connor J, Herbst R ART
Yr: 2014 Vol: 6 Nbr: 241 Abs: Pg: 241ra79

Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation and fibrosis, through integrin ávâ8-mediated activation of TGF-â
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Hideya Kitamura, Stephanie Cambier, Sangeeta Somanath, Tyren Barker, Shunsuke Minagawa, Je ART
Yr: 2011 Vol: 121 Nbr: 7 Abs: Pg: 2863-75

Interleukin-1{beta} induces increased transcriptional activation of the transforming growth factor-{beta} activating_x000D_ integrin subunit {beta}8 through altering chromatin architecture
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Markovics JA, Araya J, Cambier S, Somanath S, Gline S, Jablons D, Hill A, Wolters PJ, Nish ART
Yr: 2011 Vol: 286 Nbr: 42 Abs: Pg: 36864-74

Selective targeting of TGF-beta activation to treat fibroinflammatory airway disease
Periodical: Science Translational Medicine Index Medicus:
Authors: Minagawa S, Lou J, Seed RI, Cormier A, Wu S, Cheng Y, Murray L, Tsui P, Connor J, Herbst R ART
Yr: 2014 Vol: 6 Nbr: 241 Abs: Pg: 241ra79

Transforming Growth Factor-B and Interleukin-1B Signaling Pathways Converge on the Chemokine CCL20 Promoter
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Oliver J. Brand, Sangee Somanath, Catherine Moermans, Haruhiko Yanagisawa, Mitsuo Hashimot ART
Yr: 2015 Vol: Nbr: Abs: Pg:

A critical role for dendritic cells in the evolution of IL-1..-mediated murine airway disease
Periodical: Journal of Immunology Index Medicus:
Authors: Mitsuo Hashimoto, Haruhiko Yanagisawa, Shunsuke Minagawa, Debasish Sen, Amanda Goodsell, R ART
Yr: 2015 Vol: 194 Nbr: 8 Abs: Pg: 3962-9

TGF--Dependent Dendritic Cell Chemokinesis in Murine Models of Airway Disease
Periodical: Journal of Immunology Index Medicus:
Authors: Hashimoto, Haruhiko Yanagisawa, Shunsuke Minagawa, Debaish Sen, Royce Ma R, Lynne A Murray ART
Yr: 2015 Vol: 195 Nbr: 3 Abs: Pg: 1182-90

Role of IL-17A in murine models of COPD airway disease
Periodical: American Journal of Physiology. Lung Cell Molecular Physiology. Index Medicus:
Authors: Yanagisawa H, Hashimoto M, Minagawa S, Takasaka N, Ma R, Moermans C, Ito S, Araya J, Budel ART
Yr: 2016 Vol: Nbr: Abs: Pg: PMID:27913421

Cigarette Smoke Exposure Worsens Endotoxin-Induced Lung Injury and Pulmonary Edema in Mice
Periodical: Nicotine and Tobacco Research Index Medicus:
Authors: Gotts JE, Abbott J, Fang X, Yanagisawa H, Takasaka N, Nishimura SL, Calfee CS, Matthay MA ART
Yr: 2017 Vol: 19 Nbr: 9 Abs: Pg: 1033-1039

Integrin avb8-expressing tumor cells evade host immunity by regulating TGF-b activation in immune cells
Periodical: Journal of Clinical Investigation Insight Index Medicus:
Authors: Takasaka N, Seed RI, Cormier A, Bondesson AJ, Lou J, Elattma A, Ito S, Yanagisawa H, Hashi ART
Yr: 2018 Vol: Nbr: Abs: Pg:

Transforming Growth Factor-B and Interleukin-1B Signaling Pathways Converge on the Chemokine CCL20 Promoter
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Oliver J. Brand, Sangee Somanath, Catherine Moermans, Haruhiko Yanagisawa, Mitsuo Hashimot ART
Yr: 2015 Vol: Nbr: Abs: Pg:

A critical role for dendritic cells in the evolution of IL-1..-mediated murine airway disease
Periodical: Journal of Immunology Index Medicus:
Authors: Mitsuo Hashimoto, Haruhiko Yanagisawa, Shunsuke Minagawa, Debasish Sen, Amanda Goodsell, R ART
Yr: 2015 Vol: 194 Nbr: 8 Abs: Pg: 3962-9

TGF--Dependent Dendritic Cell Chemokinesis in Murine Models of Airway Disease
Periodical: Journal of Immunology Index Medicus:
Authors: Hashimoto, Haruhiko Yanagisawa, Shunsuke Minagawa, Debaish Sen, Royce Ma R, Lynne A Murray ART
Yr: 2015 Vol: 195 Nbr: 3 Abs: Pg: 1182-90

Role of IL-17A in murine models of COPD airway disease
Periodical: American Journal of Physiology. Lung Cell Molecular Physiology. Index Medicus:
Authors: Yanagisawa H, Hashimoto M, Minagawa S, Takasaka N, Ma R, Moermans C, Ito S, Araya J, Budel ART
Yr: 2016 Vol: Nbr: Abs: Pg: PMID:27913421

Cigarette Smoke Exposure Worsens Endotoxin-Induced Lung Injury and Pulmonary Edema in Mice
Periodical: Nicotine and Tobacco Research Index Medicus:
Authors: Gotts JE, Abbott J, Fang X, Yanagisawa H, Takasaka N, Nishimura SL, Calfee CS, Matthay MA ART
Yr: 2017 Vol: 19 Nbr: 9 Abs: Pg: 1033-1039

Integrin avb8-expressing tumor cells evade host immunity by regulating TGF-b activation in immune cells
Periodical: Journal of Clinical Investigation Insight Index Medicus:
Authors: Takasaka N, Seed RI, Cormier A, Bondesson AJ, Lou J, Elattma A, Ito S, Yanagisawa H, Hashi ART
Yr: 2018 Vol: Nbr: Abs: Pg: