Research Portfolio

Search by: Title Institution Investigator Cycle Award Type Research Priority

Funding Opportunities

Call for Applications

Join our Mailing List

Join our mailing list to be notified of new funding opportunities. Your Email To receive information about funding opportunities, events, and program updates.

John Cashman, Ph.D.

Human BioMolecular Research Institute

# of Grants: 2

Human Markers for(S)-Nicotine Biotransformation & Pathology	1993 (Cycle 2)	$58,899
Nicotine Dependence	Inno Dev & Exp Awards (IDEAS)
Novel nicotine cessation therapeutics	2000 (Cycle 9)	$802,840
Nicotine Dependence	Research Project Awards

---

Metabolism of nicotine by human liver microsomes: stereoselective formation of trans nicotine N'-oxide
Periodical: Chemical Research in Toxicology			Index Medicus:
Authors: Cashman JR, Park SB, Yang Z-C, Wrighton SA, Jacob III P, Benowitz NL				ART
Yr: 1992	Vol: 5	Nbr: 5	Abs:	Pg: 639-646

---

Expression in escherichia coli of the cloned flavin-containing monooxygenase from pig liver
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Lomri NL, Thomas J, Cashman JR				ART
Yr: 1993	Vol: 268	Nbr:	Abs:	Pg:

---

Metabolism of nicotine by human liver microsomes: stereoselective formation of trans nicotine N'-oxide
Periodical: Chemical Research in Toxicology			Index Medicus:
Authors: Cashman JR, Park SB, Yang Z-C, Wrighton SA, Jacob III P, Benowitz NL				ART
Yr: 1992	Vol: 5	Nbr: 5	Abs:	Pg: 639-646

---

Expression in escherichia coli of the cloned flavin-containing monooxygenase from pig liver
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Lomri NL, Thomas J, Cashman JR				ART
Yr: 1993	Vol: 268	Nbr:	Abs:	Pg:

---

Population distribution of human flavin-containing monoxygenase form 3: Gene polymorphisms.
Periodical: Drug Metabolism and Disposition			Index Medicus:
Authors: Cashman JR, Zhang J, Leushner J, and Braun A				ART
Yr: 2001	Vol: 29	Nbr:	Abs:	Pg: 1629-1637

---

Human and plant flavin-containing monooxygenase N-oxygenation of amines: Detoxication vs. bioactivation.
Periodical: Drug Metabolism Reviews			Index Medicus:
Authors: Cashman, JR				ART
Yr: 2002	Vol: 34	Nbr:	Abs:	Pg: 509-517

---

Inhibition of human liver mocrosomal (S)-nicotine oxidation by (-)-menthol and analogs.
Periodical: Chemical Research in Toxicology			Index Medicus:
Authors: MacDougall JM, Fandrick K, Zhang X, Serafin S, Cashman JR				ART
Yr: 0	Vol:	Nbr:	Abs:	Pg:

---

Nicotine-related alkaloids and metabolites as inhibitors of human cytochrome P-450 2A6.
Periodical: Biochemical Pharmacology			Index Medicus:
Authors: Denton TT, Zhang X, Cashman JR				ART
Yr: 2004	Vol: 67	Nbr:	Abs:	Pg: 751-756

---

Inhibition of human liver microsomal (S)-nicotine oxidation by (-) methol and analogues.
Periodical: Chemical Research in Toxicology			Index Medicus:
Authors: MacDougall JM, Fandrick K, Zhang X, Serafin SV, Cashman JR				ART
Yr: 2003	Vol: 16	Nbr:	Abs:	Pg: 988-993

---

Two new polymorphisms of the FM03 gene in Caucasian and African-American populations comparative genetic and functional studies.
Periodical: Drug Metabolism and Disposition			Index Medicus:
Authors: Lattard V, Zhang J, Tran Q, Furnes B, Schlenk D, Cashman JR				ART
Yr: 2003	Vol: 31	Nbr:	Abs:	Pg: 854-860

---

Interindividual differences of human flavin-containing monoxygenase 3: Genetic polymorphisms and functional variation.
Periodical: Drug Metabolism and Disposition			Index Medicus:
Authors: Cashman JR, Zhang J				ART
Yr: 2002	Vol: 30	Nbr:	Abs:	Pg: 1043-1052

---

Population distribution of human flavin-containing monoxygenase form 3: Gene polymorphisms.
Periodical: Drug Metabolism and Disposition			Index Medicus:
Authors: Cashman JR, Zhang J, Leushner J, and Braun A				ART
Yr: 2001	Vol: 29	Nbr:	Abs:	Pg: 1629-1637

---

Human and plant flavin-containing monooxygenase N-oxygenation of amines: Detoxication vs. bioactivation.
Periodical: Drug Metabolism Reviews			Index Medicus:
Authors: Cashman, JR				ART
Yr: 2002	Vol: 34	Nbr:	Abs:	Pg: 509-517

---

Inhibition of human liver mocrosomal (S)-nicotine oxidation by (-)-menthol and analogs.
Periodical: Chemical Research in Toxicology			Index Medicus:
Authors: MacDougall JM, Fandrick K, Zhang X, Serafin S, Cashman JR				ART
Yr: 0	Vol:	Nbr:	Abs:	Pg:

---

Nicotine-related alkaloids and metabolites as inhibitors of human cytochrome P-450 2A6.
Periodical: Biochemical Pharmacology			Index Medicus:
Authors: Denton TT, Zhang X, Cashman JR				ART
Yr: 2004	Vol: 67	Nbr:	Abs:	Pg: 751-756

---

Inhibition of human liver microsomal (S)-nicotine oxidation by (-) methol and analogues.
Periodical: Chemical Research in Toxicology			Index Medicus:
Authors: MacDougall JM, Fandrick K, Zhang X, Serafin SV, Cashman JR				ART
Yr: 2003	Vol: 16	Nbr:	Abs:	Pg: 988-993

---

Two new polymorphisms of the FM03 gene in Caucasian and African-American populations comparative genetic and functional studies.
Periodical: Drug Metabolism and Disposition			Index Medicus:
Authors: Lattard V, Zhang J, Tran Q, Furnes B, Schlenk D, Cashman JR				ART
Yr: 2003	Vol: 31	Nbr:	Abs:	Pg: 854-860

---

Interindividual differences of human flavin-containing monoxygenase 3: Genetic polymorphisms and functional variation.
Periodical: Drug Metabolism and Disposition			Index Medicus:
Authors: Cashman JR, Zhang J				ART
Yr: 2002	Vol: 30	Nbr:	Abs:	Pg: 1043-1052

---