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Joseph Zasadzinski, Ph.D.

University of California, Santa Barbara # of Grants: 4

Grants

How do tobacco smoke compounds impair lung surfactant? 1997 (Cycle 6) $74,961
Pulmonary Disease Inno Dev & Exp Awards (IDEAS)

Environmental tobacco smoke effects on lung surfactant 1999 (Cycle 8) $423,216
Pulmonary Disease Research Project Awards

Environmental tobacco smoke effects on lung surfactant 2002 (Cycle 11) $406,444
Pulmonary Disease Research Project Awards

ETS Effects on Lung Surfactant 2005 (Cycle 14) $418,874
General Biomedical Science Research Project Awards
Publications

From free-standing to transferred films: an apparatus for the continuous monitoring of surface morphology via fluorescence and AFM
Periodical: Langmuir Index Medicus:
Authors: Lee KYC, Lipp MM, Takamoto DY, Zasadzinski JA, Waring AJ ART
Yr: 0 Vol: Nbr: Abs: Pg:

Coexistence between buckled and flat monolayers
Periodical: Physical Review Letters Index Medicus:
Authors: Lipp MM, Lee KYC, Waring AJ, Zasadzinski JA ART
Yr: 1998 Vol: 81 Nbr: Abs: Pg: 1650-1653

Effects of lung surfactant specific protein SP-B and model SP-B peptide on lipid monolayers at the air-water interface
Periodical: Colloids and Surfaces Index Medicus:
Authors: Lee KYC, Lipp MM, Waring AJ, Zasadzinski JA ART
Yr: 1997 Vol: 128 Nbr: Abs: Pg: 225-242

Direct observation of morphology changes induced by lung surfactant protein SP-B
Periodical: Laser Techniques for Biological Systems Index Medicus:
Authors: Lee KYC, Lipp MM, Takamoto DY, Zasadzinski J ART
Yr: 1998 Vol: 3273 Nbr: Abs: Pg: 115-133

The role of lung surfactant proteins and lipids in monolayer stability
Periodical: Biophysical Journal Index Medicus:
Authors: Ding J, Takamoto DY, von Nahmen A, et al ART
Yr: 0 Vol: Nbr: Abs: Pg:

Surfactant protein B and C analogs
Periodical: Molecular Genetics and Metabolism Index Medicus:
Authors: Waring AJ, Walther F, Zasadzinski J, Sherwood M ART
Yr: 2000 Vol: 71 Nbr: Abs: Pg: 342-351

Effects of lung surfactant proteins SP-B and SP-C and palmitic acid on monolayer stability
Periodical: Biophysical Journal Index Medicus:
Authors: Ding J, von Nahmen A, Takamoto DK, et al ART
Yr: 2001 Vol: 80 Nbr: Abs: Pg: 2262 - 2272

Interaction of lung surfactant proteins with anionic phospholipids
Periodical: Biophysical Journal Index Medicus:
Authors: Takamoto DY, Lipp MM, von Nahmen A, Lee KYC, Waring AJ, Zasadzinski J ART
Yr: 2001 Vol: 80 Nbr: Abs: Pg:

The incorporation of lung sufactant protein SP-B into lipid monolayers at the air-fluid interface
Periodical: Biophysical Journal Index Medicus:
Authors: Lee KYC, Majewski J, Kuhl TL, et al ART
Yr: 2001 Vol: 81 Nbr: Abs: Pg: 572 - 585

Changes in model lung surfactant monolayers induced by palmitic acid
Periodical: Langmuir Index Medicus:
Authors: Bringezu F, Ding J, Brezesinski G, Zasadzinski J ART
Yr: 2001 Vol: 17 Nbr: Abs: Pg: 4641 - 4648

A concentration dependent mechanism by which serum albumin inactivates replacement lung surfactants.
Periodical: Biophysical Journal Index Medicus:
Authors: Warriner HE, Ding J, Waring A, and Zasadzinski A ART
Yr: 2002 Vol: 82 Nbr: Abs: Pg: 835 - 842

Influence of pulmonary surfactant protein B on structures of condensed model lung surfactant monolayers.
Periodical: Langmuir Index Medicus:
Authors: Bringezu F, Ding J, Brezesinski G, Waring A and Zasadzinski A ART
Yr: 2002 Vol: 18 Nbr: Abs: Pg: 2319 - 2325

Influence of palmitic acid and hexidecanol on the phase transition temperatures and molecular packing of DPPC monolayers at the air-water interface.
Periodical: Journal of Chemical Physics Index Medicus:
Authors: Lee KYC et al. ART
Yr: 2002 Vol: 115 Nbr: Abs: Pg: 774 - 783

Viscosity of two-dimensional suspensions.
Periodical: Physical Review Letters Index Medicus:
Authors: Ding J, Warriner HE, and Zasadzinski JA ART
Yr: 2002 Vol: 88 Nbr: 168102 Abs: Pg: 1 - 4

A magnetic needle viscometer for langmuir monolayers.
Periodical: Langmuir Index Medicus:
Authors: Ding J, Warriner HE, Schwartz DK, and Zasadzinski J ART
Yr: 2002 Vol: 18 Nbr: Abs: Pg: 2800 - 2806

Interaction of lung surfactant proteins with anionic phospholipids.
Periodical: Biophysical Journal Index Medicus:
Authors: Takamoto DY, et al. ART
Yr: 2001 Vol: 81 Nbr: Abs: Pg: 153 - 169

Stable ordering in langmuir-blodgett films.
Periodical: Science Index Medicus:
Authors: Takamoto DY, et al. ART
Yr: 2001 Vol: 293 Nbr: Abs: Pg: 1292 - 1295

Conformational mapping of the N-terminal segment of surfactant protein B in lipid using 13C-enhanced fourier transform infrared spectroscopy.
Periodical: Journal of Peptide Research Index Medicus:
Authors: Gordon LM, et al. ART
Yr: 2000 Vol: 55 Nbr: Abs: Pg: 330 - 347

The physics and physiology of lung surfactants.
Periodical: Current Opinion in Colloid and Interface Science Index Medicus:
Authors: Zasadzinski JA, Ding J, Warriner H, and Bringezu F ART
Yr: 2001 Vol: 6 Nbr: Abs: Pg: 506 - 513

The incorporation of lung surfactant specific protein SP-B into lipid monolayers at the air-fluid interface.
Periodical: Material Research Society Symposium Proceedings: Applications of Synchrotron Radiation Techniques to Materials Science. Index Medicus:
Authors: Lee KYC, Majewski J, Kuhl TL, et al. ART
Yr: 2000 Vol: 590 Nbr: Abs: Pg: 177 - 182

Environmental tobacco smoke effects on the primary lipids of lung surfactants.
Periodical: Langmuir Index Medicus:
Authors: Bringezu F, Ding J, and Zasadzinski J ART
Yr: 2003 Vol: 19 Nbr: Abs: Pg: 2900-2907

Nanostructural changes in lung surfactant monolayers induced by interactions between POPG and surfactant protein SP-B.
Periodical: Langmuir Index Medicus:
Authors: Ding J, Doudevski I, Warriner HE, Zasadzinski J ART
Yr: 2003 Vol: 19 Nbr: Abs: Pg: 1539-1550

Environmental tobacco smoke effects on the primary lipids of lung surfactant.
Periodical: Langmuir Index Medicus:
Authors: Bringezu F, Pinkerton K, Zasadzinski J ART
Yr: 2003 Vol: 19 Nbr: Abs: Pg: 1900-1907

Electrostatic barrier to recovery of dipalmitoylphosphatidylglycerol monolayers after collapse
Periodical: Biophysical Journal Index Medicus:
Authors: Alig TF, Warriner HE, Lee L, Zasadzinski J ART
Yr: 2004 Vol: 86 Nbr: Abs: Pg: 897-904

Linear dependence of surface drag on surface viscosity
Periodical: Physical Review Letters Index Medicus:
Authors: Alonso C, Zasadzinski J ART
Yr: 2004 Vol: 69 Nbr: 021602 Abs: Pg: 1-6

Exogenous lung surfactant survanta in vitro function-composition relationship
Periodical: Langmuir Index Medicus:
Authors: Alonso C, Alig T, Zasadzinski J ART
Yr: 2004 Vol: Nbr: Abs: Pg:

Keeping ling surfactants where it belongs, protein regulation of surfactant viscosity April 25, 2005
Periodical: Biophysical Journal Index Medicus:
Authors: Joseph Zasadzinski ART
Yr: 0 Vol: Nbr: Abs: Pg:

More than a Monolayer, Relating Lung Surfactant Structure and Mechanics to Composition 4188-4202
Periodical: Biophysical Journal Index Medicus:
Authors: Zasadzinski, J ART
Yr: 2004 Vol: 87 Nbr: Abs: Pg: 4188 - 4202

Electrostatic Barrier to Recovery of Dipalmitoylphosphatidylycerol Monolayers after collapse
Periodical: Index Medicus:
Authors: J. Zasadzinski ART
Yr: Vol: Nbr: Abs: Pg:

Linear Dependence of Surface Drag on Surface Viscossity, 2004
Periodical: Physical Review Letters Index Medicus:
Authors: J. Zasadzinski ART
Yr: 2004 Vol: 69 Nbr: Abs: Pg: 021602 - 1.6

Inactivation of Pulmonary Surfactant Due to Serum -Inhibited Adsorption and Reversal by Hydrophilic Polymers
Periodical: Index Medicus:
Authors: H.W. Taeusch, J. Bernadino de la Serna, J. Perez-Gil, C Alonso and J Zasadzinski ART
Yr: Vol: Nbr: Abs: Pg:

Inactivation of Pulmonary Surfactant Due to Serum-inhibited Adsorption and Reversal by Hydrophilic Polymers Theory.
Periodical: Index Medicus:
Authors: J. Zasadzinski, T.F. Alig, C Alonso, J.Bernadino de la Serna, J Perez Gil and H.W. Taeusch ART
Yr: Vol: Nbr: Abs: Pg:

Inhibition of Pulmonary Surfactant Adsorption by Serum and the Mechanisms of Reversal by Hydrophilic polymers Therory
Periodical: Biophysical Journal Index Medicus:
Authors: Joseph Zasadzinski ART
Yr: 2005 Vol: 89 Nbr: Abs: Pg: 1621-1629

A Novel camptotheicin Analog with Enhanced Antitumor Activity.
Periodical: Index Medicus:
Authors: Li-Xi Yang ART
Yr: Vol: Nbr: Abs: Pg:

Rediscovering the Schultz-Hardy Rule in competitive adsorption of surfactant to an air-water interface.
Periodical: Langmuir Index Medicus:
Authors: Stenger PC, Isbell SG, St. Hillaire D, Zasadzinski JA ART
Yr: 2009 Vol: DOI Nbr: 10.1021 Abs: Pg: la9009724

Competitive Adsorption: A physical model for lung surfactant inactivation via quantitative Brewster Angle microscopy.
Periodical: Langmuir Index Medicus:
Authors: Fernsler J, Zasadzinski JA ART
Yr: 2009 Vol: Nbr: 25 Abs: Pg: 8131-8143

Physical charactrerzation of environmental tobacco smoke effects on lung surfactant mechanical and morphological properties.
Periodical: Biochemica et Biophysica Acta Index Medicus:
Authors: Stenger PC, Alonso C, Zasadzinski JA, Waring AJ, Jung CL, Pinkerton K ART
Yr: 2009 Vol: Nbr: 1788 Abs: Pg: 358-370

Mechanisms of polyelectrolyte enhanced surfactant adsorption at the air-water interface.
Periodical: Biochemica et Biophysica Acta Index Medicus:
Authors: Stenger PC, Palazoglu O, Zasadzinski JA ART
Yr: 2009 Vol: Nbr: 1788 Abs: Pg: 1033-1043

Molecular weight dependence of the depletion attraction and its effects on the competitive adsorption of lung surfactant.
Periodical: Biochemica et Biophysica Acta Index Medicus:
Authors: Stenger P, Isbell S, Zasadzinski JA ART
Yr: 2008 Vol: Nbr: 1778 Abs: Pg: 2032-2040