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Linda Curtiss, Ph.D.

Scripps Research Institute

# of Grants: 5

Developing treatments that lower blood cholesterol levels	1997 (Cycle 6)	$746,536
Cardiovascular Disease	Research Project Awards
Functional Synthetic Peptide Mimics of Apolipoprotein E	1994 (Cycle 3)	$653,578
Cardiovascular Disease	Research Project Awards
Macrophage function in atherosclerosis	2000 (Cycle 9)	$709,200
Cardiovascular Disease	Research Project Awards
Tobacco smoke, inflammation & atherosclerosis	2001 (Cycle 10)	$754,932
Cardiovascular Disease	Research Project Awards
Tobacco use and atherosclerosis protection by paraoxonase	2004 (Cycle 13)	$729,234
Cardiovascular Disease	Research Project Awards

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A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophage in atherosclerotic lesions of LDL-receptor-dificient mice
Periodical: Journal of Clinical Investigation			Index Medicus:
Authors: Boisvert WA, Santiago R, Curtiss LK, Terkeltaub RA				ART
Yr: 1998	Vol: 101	Nbr:	Abs:	Pg: 353-363

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A minimally lipidated form of cell-derived apo E exhibits isoform-specific stimulation of neurite outgrowth in the absence of exogenous lipids or lipoproteins
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: DeMattos RB, Curtiss LK, Williams DL				ART
Yr: 1998	Vol: 273	Nbr:	Abs:	Pg: 4206-4212

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Chemokines and atherosclerosis
Periodical: Current Opinion in Lipidology			Index Medicus:
Authors: Terkeltaub R, Boisvert WA, Curtiss LK				ART
Yr: 1998	Vol: 9	Nbr:	Abs:	Pg: 397-405

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An apolipoprotein E synthetic peptide selectively modulates the transcription of the gene for rat ovarian theca and interstitial cell P450 17 alpha-hydroxylase, C17-20 lyase
Periodical: Journal of Lipid Research			Index Medicus:
Authors: Zhang G, Curtiss LK, Wade RL, Dyer CA				ART
Yr: 1998	Vol: 39	Nbr:	Abs:	Pg: 2406-2414

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Radiolabeled MDA2, an oxidation-specific monoclonal antibody identifies native atherosclerotic lesions in vivo
Periodical: Journal of Nuclear Cardiology			Index Medicus:
Authors: Tsimikas S, Palinski W, Halpern SE, Yeung DW, Curtiss LK, Witztum JL				ART
Yr: 1999	Vol: 6	Nbr:	Abs:	Pg: 41-53

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IL-8 and its receptor CXCR2 in atherosclerosis
Periodical: Immunologic Research			Index Medicus:
Authors: Boisvert WA, Curtiss LK, Terkeltaub RA				ART
Yr: 2000	Vol: 21	Nbr:	Abs:	Pg: 129-137

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Leukocyte CD11b expression is not essential for the development of atherosclerosis in mice
Periodical: Journal of Lipid Research			Index Medicus:
Authors: Kubo N, Boisvert WA, Ballantyne CM, Curtiss LK				ART
Yr: 2000	Vol:	Nbr:	Abs:	Pg:

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Apolipoprotein E and atherosclerosis
Periodical: Current Opinion in Lipidology			Index Medicus:
Authors: Curtiss LK, Boisvert WA				ART
Yr: 2000	Vol: 11	Nbr:	Abs:	Pg: 243-251

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Apolipoprotein E and atherosclerosis, a protein with multiple hats
Periodical: Arteriosclerosis, Thrombosis, and Vascular Biology			Index Medicus:
Authors: Curtiss LK				ART
Yr: 0	Vol:	Nbr:	Abs:	Pg:

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A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophage in atherosclerotic lesions of LDL-receptor-dificient mice
Periodical: Journal of Clinical Investigation			Index Medicus:
Authors: Boisvert WA, Santiago R, Curtiss LK, Terkeltaub RA				ART
Yr: 1998	Vol: 101	Nbr:	Abs:	Pg: 353-363

---

A minimally lipidated form of cell-derived apo E exhibits isoform-specific stimulation of neurite outgrowth in the absence of exogenous lipids or lipoproteins
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: DeMattos RB, Curtiss LK, Williams DL				ART
Yr: 1998	Vol: 273	Nbr:	Abs:	Pg: 4206-4212

---

Chemokines and atherosclerosis
Periodical: Current Opinion in Lipidology			Index Medicus:
Authors: Terkeltaub R, Boisvert WA, Curtiss LK				ART
Yr: 1998	Vol: 9	Nbr:	Abs:	Pg: 397-405

---

An apolipoprotein E synthetic peptide selectively modulates the transcription of the gene for rat ovarian theca and interstitial cell P450 17 alpha-hydroxylase, C17-20 lyase
Periodical: Journal of Lipid Research			Index Medicus:
Authors: Zhang G, Curtiss LK, Wade RL, Dyer CA				ART
Yr: 1998	Vol: 39	Nbr:	Abs:	Pg: 2406-2414

---

Radiolabeled MDA2, an oxidation-specific monoclonal antibody identifies native atherosclerotic lesions in vivo
Periodical: Journal of Nuclear Cardiology			Index Medicus:
Authors: Tsimikas S, Palinski W, Halpern SE, Yeung DW, Curtiss LK, Witztum JL				ART
Yr: 1999	Vol: 6	Nbr:	Abs:	Pg: 41-53

---

IL-8 and its receptor CXCR2 in atherosclerosis
Periodical: Immunologic Research			Index Medicus:
Authors: Boisvert WA, Curtiss LK, Terkeltaub RA				ART
Yr: 2000	Vol: 21	Nbr:	Abs:	Pg: 129-137

---

Leukocyte CD11b expression is not essential for the development of atherosclerosis in mice
Periodical: Journal of Lipid Research			Index Medicus:
Authors: Kubo N, Boisvert WA, Ballantyne CM, Curtiss LK				ART
Yr: 2000	Vol:	Nbr:	Abs:	Pg:

---

Apolipoprotein E and atherosclerosis
Periodical: Current Opinion in Lipidology			Index Medicus:
Authors: Curtiss LK, Boisvert WA				ART
Yr: 2000	Vol: 11	Nbr:	Abs:	Pg: 243-251

---

Apolipoprotein E and atherosclerosis, a protein with multiple hats
Periodical: Arteriosclerosis, Thrombosis, and Vascular Biology			Index Medicus:
Authors: Curtiss LK				ART
Yr: 0	Vol:	Nbr:	Abs:	Pg:

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Interferon-gamma inhibits macrophage apolipoprotein E production by posttranslational mechanisms
Periodical: Journal of Clinical Investigation			Index Medicus:
Authors: Brand K, Mackman N, Curtiss LK				ART
Yr: 1993	Vol: 91	Nbr: 5	Abs:	Pg: 2031-2039

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Structural features of synthetic peptides of apolipoprotein E that bind the LDL receptor
Periodical: Journal of Lipid Research			Index Medicus:
Authors: Dyer CA, Cistola DP, Parry GC, Curtiss LK				ART
Yr: 1995	Vol: 36	Nbr: 1	Abs:	Pg: 80-88

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Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantion
Periodical: Journal of Clinical Investigation			Index Medicus:
Authors: Boisvert WA, Spangenberg J, Curtiss LK				ART
Yr: 1995	Vol: 96	Nbr: 2	Abs:	Pg: 1118-1124

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Interferon-gamma inhibits macrophage apolipoprotein E production by posttranslational mechanisms
Periodical: Journal of Clinical Investigation			Index Medicus:
Authors: Brand K, Mackman N, Curtiss LK				ART
Yr: 1993	Vol: 91	Nbr: 5	Abs:	Pg: 2031-2039

---

Structural features of synthetic peptides of apolipoprotein E that bind the LDL receptor
Periodical: Journal of Lipid Research			Index Medicus:
Authors: Dyer CA, Cistola DP, Parry GC, Curtiss LK				ART
Yr: 1995	Vol: 36	Nbr: 1	Abs:	Pg: 80-88

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Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantion
Periodical: Journal of Clinical Investigation			Index Medicus:
Authors: Boisvert WA, Spangenberg J, Curtiss LK				ART
Yr: 1995	Vol: 96	Nbr: 2	Abs:	Pg: 1118-1124

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Participation of innate and acquired immunity in atherosclerosis
Periodical: Immunologic Research			Index Medicus:
Authors: Curtiss LK, Kubo N, Schiller NK, Boisvert WA				ART
Yr: 2000	Vol: 21	Nbr:	Abs:	Pg: 167-176

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Participation of innate and acquired immunity in atherosclerosis
Periodical: Immunologic Research			Index Medicus:
Authors: Curtiss LK, Kubo N, Schiller NK, Boisvert WA				ART
Yr: 2000	Vol: 21	Nbr:	Abs:	Pg: 167-176

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