Timothy O'Toole, Ph.D.
Scripps Research Institute
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# of Grants: 1 |
Grants
Publications
Distinct functions of integrin alpha and beta subunit cytoplasmic domains in cell spreading and formation of focal adhesions |
Periodical: Journal of Cell Biology |
Index Medicus: |
Authors: Ylanne J, Chen Y, O'Toole TE, Loftus JC, Takada Y, Ginsberg MH |
ART |
Yr: 1993 |
Vol: 122 |
Nbr: 1 |
Abs: |
Pg: 223-233 |
Integrin cytoplasmic domains mediate inside-out signal transduction |
Periodical: Journal of Cell Biology |
Index Medicus: |
Authors: O'Toole TE, Katagiri Y, Faull R, et al |
ART |
Yr: 1994 |
Vol: 124 |
Nbr: 6 |
Abs: |
Pg: 1047-1059 |
"Inside-out" signal transduction inhibited by isolated integrin cytoplasmic domains |
Periodical: Journal of Biological Chemistry |
Index Medicus: |
Authors: Chen Y-P, O'Toole TE, Shipley T, et al |
ART |
Yr: 1994 |
Vol: 269 |
Nbr: 28 |
Abs: |
Pg: 18307-18310 |
Regulation of integrin function and cellular adhesion |
Periodical: Stem Cells |
Index Medicus: |
Authors: Stuiver I, O'Toole TE |
ART |
Yr: 1995 |
Vol: 13 |
Nbr: 3 |
Abs: |
Pg: 250-262 |
Regulation of integrin affinity states through an NPXY motif in the beta subunit cytoplasmic domain |
Periodical: Journal of Biological Chemistry |
Index Medicus: |
Authors: O'Toole TE, Ylanne J, Culley BC |
ART |
Yr: 1995 |
Vol: 270 |
Nbr: 15 |
Abs: |
Pg: 8553-8558 |
A conserved membrane-proximal region of an integrin cytoplasmic domain specifies ligand binding afinity |
Periodical: Journal of Biological Chemistry |
Index Medicus: |
Authors: Hughes PE, O'Toole TE, Ylanne J, Shattil SJ, Ginsberg MH |
ART |
Yr: 1995 |
Vol: 270 |
Nbr: 21 |
Abs: |
Pg: 12411-12417 |
A point mutation in the integrin beta 3 cytoplasmic domain (S752P) impairs bidirectional signaling through alpha II beta 3 (platelet glycoprotein II-b-IIIa). |
Periodical: Blood |
Index Medicus: |
Authors: Chen YP, O'Toole TE, Rosa JP, Ginsberg MH |
ART |
Yr: 1994 |
Vol: 84 |
Nbr: |
Abs: |
Pg: 1857-1865 |
Modulation of cell adhesion by changes in alpha L beta 2 (LFA-1,CD11a/CD18) cytoplasmic domain/cytoskeletal interaction |
Periodical: Journal of Experimental Medicine |
Index Medicus: |
Authors: Peter K, O'Toole TE |
ART |
Yr: 1995 |
Vol: 181 |
Nbr: |
Abs: |
Pg: 315-326 |
Mutation of the cytoplasmic domain of the integrinbeta 3 subunit: differential effects on cell spreading, recruitment to adhesion plaques, endocytosis and phagocytosis |
Periodical: Journal of Biological Chemistry |
Index Medicus: |
Authors: Ylanne J, Huuskonen J, O'Toole TE, Ginsberg MH, Virtanen I, Gahmberg CG |
ART |
Yr: 1995 |
Vol: 270 |
Nbr: |
Abs: |
Pg: 9550-9557 |
Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmictail of the integrin beta 3 subunit |
Periodical: Journal of Cell Biology |
Index Medicus: |
Authors: Shattil SJ, O'Toole TE, Eigenthaler M, Thon V, Williams M, Babior BM, Ginsberg MH |
ART |
Yr: 1995 |
Vol: 131 |
Nbr: |
Abs: |
Pg: 807-816 |
Distinct functions of integrin alpha and beta subunit cytoplasmic domains in cell spreading and formation of focal adhesions |
Periodical: Journal of Cell Biology |
Index Medicus: |
Authors: Ylanne J, Chen Y, O'Toole TE, Loftus JC, Takada Y, Ginsberg MH |
ART |
Yr: 1993 |
Vol: 122 |
Nbr: 1 |
Abs: |
Pg: 223-233 |
Integrin cytoplasmic domains mediate inside-out signal transduction |
Periodical: Journal of Cell Biology |
Index Medicus: |
Authors: O'Toole TE, Katagiri Y, Faull R, et al |
ART |
Yr: 1994 |
Vol: 124 |
Nbr: 6 |
Abs: |
Pg: 1047-1059 |
"Inside-out" signal transduction inhibited by isolated integrin cytoplasmic domains |
Periodical: Journal of Biological Chemistry |
Index Medicus: |
Authors: Chen Y-P, O'Toole TE, Shipley T, et al |
ART |
Yr: 1994 |
Vol: 269 |
Nbr: 28 |
Abs: |
Pg: 18307-18310 |
Regulation of integrin function and cellular adhesion |
Periodical: Stem Cells |
Index Medicus: |
Authors: Stuiver I, O'Toole TE |
ART |
Yr: 1995 |
Vol: 13 |
Nbr: 3 |
Abs: |
Pg: 250-262 |
Regulation of integrin affinity states through an NPXY motif in the beta subunit cytoplasmic domain |
Periodical: Journal of Biological Chemistry |
Index Medicus: |
Authors: O'Toole TE, Ylanne J, Culley BC |
ART |
Yr: 1995 |
Vol: 270 |
Nbr: 15 |
Abs: |
Pg: 8553-8558 |
A conserved membrane-proximal region of an integrin cytoplasmic domain specifies ligand binding afinity |
Periodical: Journal of Biological Chemistry |
Index Medicus: |
Authors: Hughes PE, O'Toole TE, Ylanne J, Shattil SJ, Ginsberg MH |
ART |
Yr: 1995 |
Vol: 270 |
Nbr: 21 |
Abs: |
Pg: 12411-12417 |
A point mutation in the integrin beta 3 cytoplasmic domain (S752P) impairs bidirectional signaling through alpha II beta 3 (platelet glycoprotein II-b-IIIa). |
Periodical: Blood |
Index Medicus: |
Authors: Chen YP, O'Toole TE, Rosa JP, Ginsberg MH |
ART |
Yr: 1994 |
Vol: 84 |
Nbr: |
Abs: |
Pg: 1857-1865 |
Modulation of cell adhesion by changes in alpha L beta 2 (LFA-1,CD11a/CD18) cytoplasmic domain/cytoskeletal interaction |
Periodical: Journal of Experimental Medicine |
Index Medicus: |
Authors: Peter K, O'Toole TE |
ART |
Yr: 1995 |
Vol: 181 |
Nbr: |
Abs: |
Pg: 315-326 |
Mutation of the cytoplasmic domain of the integrinbeta 3 subunit: differential effects on cell spreading, recruitment to adhesion plaques, endocytosis and phagocytosis |
Periodical: Journal of Biological Chemistry |
Index Medicus: |
Authors: Ylanne J, Huuskonen J, O'Toole TE, Ginsberg MH, Virtanen I, Gahmberg CG |
ART |
Yr: 1995 |
Vol: 270 |
Nbr: |
Abs: |
Pg: 9550-9557 |
Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmictail of the integrin beta 3 subunit |
Periodical: Journal of Cell Biology |
Index Medicus: |
Authors: Shattil SJ, O'Toole TE, Eigenthaler M, Thon V, Williams M, Babior BM, Ginsberg MH |
ART |
Yr: 1995 |
Vol: 131 |
Nbr: |
Abs: |
Pg: 807-816 |