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Victor Dzau, M.D.

Duke University # of Grants: 1

Grants

Vascular Response to Injury: Potentiation by Nicotine 1992 (Cycle 1) $572,478
Cardiovascular Disease Research Project Awards
Publications

Persistent endothelial and adrengic dysfunction after angioplasty
Periodical: Journal of the American College of Cardiology Index Medicus:
Authors: Cooke JP, Dasari P, Krieger JE, et al. ART
Yr: 1991 Vol: Nbr: Abs: Pg:

The role of angiotensin in the control of vascular smooth muscle growth
Periodical: Journal of Vascular Surgery Index Medicus:
Authors: Pratt RE, Itoh H, Gibbons GH, et al. ART
Yr: 0 Vol: Nbr: Abs: Pg:

Localization and differential regulation of angiotensinogen mRNA expression in the vessel wall
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Naftilan AJ, Zuo WM, Ingelfinger J, Ryan TJ, Pratt RE, Dzau VJ ART
Yr: 1991 Vol: 87 Nbr: 4 Abs: Pg: 1300-1311

Interaction of ANP and angiotensin II on protooncogene expression and vascular cell growth
Periodical: Biochemistry and Biophysics Research Communications Index Medicus:
Authors: Itoh H, Pratt RE, Dzau VJ ART
Yr: 1991 Vol: 176 Nbr: 3 Abs: Pg: 1601-1609

Transforming growth factor: Beta expression modulates the bifunctional growth response of vascular smooth muscle cells to angiotensin II
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Gibbons GH, Pratt RE, Dzau VJ ART
Yr: 0 Vol: Nbr: Abs: Pg:

Identification of beta-receptor for natriuretic peptide in human kidney
Periodical: Endocrinology Index Medicus:
Authors: Canaan-Kuhl S, Jamison RL, Myers BD, Pratt RE ART
Yr: 0 Vol: Nbr: Abs: Pg:

Mas oncogene receptor coupling and peptide specificity in Balb 3T3 and vascular smooth muscle cells
Periodical: American Journal of the Medical Sciences Index Medicus:
Authors: Andrawis NS, Brock TA, Dzau VJ, Pratt RE ART
Yr: 1991 Vol: 302 Nbr: 6 Abs: Pg: 329-334

Glucose directly stimulates the growth of vascular smooth muscle cells in culture
Periodical: Clinical Research Index Medicus:
Authors: Koibuchi Y, Lee WS, Pratt RE ART
Yr: 0 Vol: Nbr: Abs: Pg:

The role of angiotensin in the control of vascular smooth muscle cells
Periodical: Journal of Vascular Medicine and Biology Index Medicus:
Authors: Pratt RE, Itoh H, Gibbons GH, Dzau VJ ART
Yr: 1991 Vol: 3 Nbr: 1 Abs: Pg: 25-29

Role of protein kinase (PK) C in the angiotensin (Ang) II induced growth of vascular smooth muscle cells (VSMC)
Periodical: Clinical Research Index Medicus:
Authors: Koibuchi Y, Gibbons GH, Lee WS, Pratt RE ART
Yr: 0 Vol: Nbr: Abs: Pg:

Molecular mechanisms of the vascular renin angiotensin system in myointimal hyperplasia
Periodical: Hypertension Index Medicus:
Authors: Dzau VJ, Gibbons GH, Pratt RE ART
Yr: 1991 Vol: 18 Nbr: 4 Suppl Abs: Pg: II100-II105

Developmentally regulated production of angiotensin converting enzyme in cultured rat vascular smooth muscle cells
Periodical: Clinical Research Index Medicus:
Authors: Rakugi H, Wang D, Giachelli C, Schwartz S, Dzau VJ, Pratt RE ART
Yr: 0 Vol: Nbr: Abs: Pg:

Arginine restores cholinergic relaxation of hyperscholersterolemic rabbit thoracic aorta
Periodical: Circulation Index Medicus:
Authors: Cooke JP, Andon NA, Girerd XJ, Hirsch AT, Creager MA ART
Yr: 1991 Vol: 83 Nbr: Abs: Pg: 1057-1062

Anti-atherogenic effects of L-arginine in the hyperscholesterolemic rabbit
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Cooke JP, Singer AH, Tsao P, Zera P, Rowan RA, Billingham ME ART
Yr: 1992 Vol: 90 Nbr: Abs: Pg: 1168-1172

L-arginine normalizes endothelial function in cerebral vessels from hypercholesterolemic rabbit
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Rossitch E Jr, Alexander E III, Black P, Cooke JP ART
Yr: 1991 Vol: 87 Nbr: Abs: Pg: 1295-1299

Molecular biology of hypertension
Periodical: Hypertension Index Medicus:
Authors: Krieger JE, Dzau VJ ART
Yr: 1991 Vol: 18 Nbr: 3 Suppl Abs: Pg: I3-I17

Tissue-specific activation of cardiac angiotensin converting enzyme in experimental heart failure
Periodical: Circulation Research Index Medicus:
Authors: Hirsch AT, Talsness CE, Schunkert H, Paul M, Dzau VJ ART
Yr: 1991 Vol: 69 Nbr: 2 Abs: Pg: 475-482

Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Cooke JP, Rossitch E, Andon NA, Loscalzo J, Dzau VJ ART
Yr: 1991 Vol: 88 Nbr: 5 Abs: Pg: 1663-1671

Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat
Periodical: Cell Index Medicus:
Authors: Jacob HJ, Lindpainter K, Lincoln SE, et al ART
Yr: 1991 Vol: 67 Nbr: Abs: Pg: 213-224

Endothelium and growth factors in vascular remodeling of hypertension
Periodical: Hypertension Index Medicus:
Authors: Dzau VJ, Gibbons GH ART
Yr: 1991 Vol: 18 Nbr: 3 Suppl Abs: Pg: III115-III121

Identification of negative regulatory element involved in tissue-specific expression of mouse renin genes
Periodical: Proceedings of the National Academy of Sciences of the United States of America Index Medicus:
Authors: Barrett G, Horiuchi M, Paul M, Pratt RE, Nakamura N, Dzau VJ ART
Yr: 1992 Vol: 89 Nbr: 3 Abs: Pg: 885-889

Cell-dependent postranslational processing and secretion of recombinant mouse renin-2
Periodical: American Journal of Physiology Index Medicus:
Authors: Paul M, Nakamura N, Pratt RE, Burt DW, Dzau VJ ART
Yr: 1992 Vol: 262 Nbr: 2 Pt 1 Abs: Pg: E224-E229

Atrial natriuretic polypeptide as a novel antigrowth factor of endothelial cells
Periodical: Hypertension Index Medicus:
Authors: Itoh H, Pratt RE, Ohno M, Dzau VJ ART
Yr: 1992 Vol: 19 Nbr: 6 Pt 2 Abs: Pg: 758-761

Characterization of nuclear angiotensin II in binding sites in rat liver and comparison with plasma membrane receptors
Periodical: Endocrinology Index Medicus:
Authors: Tang SS, Rogg H, Schumacher R, Dzau VJ ART
Yr: 1992 Vol: 131 Nbr: Abs: Pg: 374-380

Cloning, characterization and expression of two angiotensin receptor (AT-1) isoforms from the mouse genome
Periodical: Biochemistry and Biophysics Research Communications Index Medicus:
Authors: Sasamura H, Hein L, Krieger JE, Pratt RE, Kobilka BK, Dzau VJ ART
Yr: 1992 Vol: 185 Nbr: 1 Abs: Pg: 253-259

Differential effects of antihypertensive agents in experimental and human anterosclerosis
Periodical: Journal of Vascular Medicine and Biology Index Medicus:
Authors: Omoigui N, Dzau VJ ART
Yr: 1992 Vol: 3 Nbr: Abs: Pg: 382-391

Tissue specificity of renin promoter activity and regulation in the mouse
Periodical: American Journal of Physiology Index Medicus:
Authors: Paul M, Burt DW, Krieger JE, Nakamura N, Dzau VJ ART
Yr: 1992 Vol: 262 Nbr: 5 Pt 1 Abs: Pg: E644-E650

Vascular smooth muscle cell hypertrophy vs hyperplasia. Autocrine transforming growth factor-beta1 expression determines growth response to angiotensin II
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Gibbons GH, Pratt RE, Dzau VJ ART
Yr: 1992 Vol: 90 Nbr: Abs: Pg: 456-461

Tissue renin-angiotensin system in the experimental restenosis after vascular injury: evidence for local activation
Periodical: Journal of Cardiovascular Pharmacology Index Medicus:
Authors: Dzau VJ, Pratt RE ART
Yr: 1992 Vol: 20 Nbr: Suppl B Abs: Pg: S28-S32

L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Creager MA, Gallagher SJ, Girerd XJ, Coleman SM, Dzau VJ, Cooke JP ART
Yr: 1992 Vol: 90 Nbr: Abs: Pg: 1248-1253

Specific blockade of basic fibroblast growth factor gene expression in endothelial cells by antisense oligonucleotide
Periodical: Biochemistry and Biophysics Research Communications Index Medicus:
Authors: Itoh H, Mukoyama M, Pratt RE, Dzau VJ ART
Yr: 1992 Vol: 188 Nbr: Abs: Pg: 1205-1213

Antisense technology to clock autocrine growth factors
Periodical: Journal of Vascular Surgery Index Medicus:
Authors: Dzau VJ, Pratt RE ART
Yr: 1992 Vol: 15 Nbr: 5 Abs: Pg: 934-935

Autocrine and paracrine mechanisms in the pathophysiology of heart failure
Periodical: American Journal of Cardiology Index Medicus:
Authors: Dzau VJ ART
Yr: 1992 Vol: 70 Nbr: 10 Abs: Pg: 4C-11C

Feedback regulation of angiotensin converting enzyme activity and mRNA levels by angiotensin II
Periodical: Circulation Research Index Medicus:
Authors: Schunkert H, Ingerfinger JR, Hirsch AT, et al ART
Yr: 1993 Vol: 72 Nbr: Abs: Pg: 312-318

The role of mechanical and humoral factors in growth regulation of vascular smooth muscle and cardiac myocytes
Periodical: Current Opinions on Nephrology and Hypertension Index Medicus:
Authors: Dzau VJ ART
Yr: 1993 Vol: 2 Nbr: Abs: Pg: 27-32

Gene expression of the renin-angiotensin system in human tissues. Quantitative analysis by the polymerase chain reaction
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Paul M, Wagner J, Dzau VJ ART
Yr: 1993 Vol: 91 Nbr: 5 Abs: Pg: 2058-2064

Multiple autocrine growth factors modulate vascular smooth muscle cell growth response to angiotensin II
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Itoh H, Mukoyama M, Pratt RE, Gibbons GH, Dzau VJ ART
Yr: 1993 Vol: 91 Nbr: 5 Abs: Pg: 2268-2274

Heterogeneity of angiotensin synthetic pathways and receptor subtypes: Physiological and pharmacological implications
Periodical: Journal of Hypertension Index Medicus:
Authors: Dzau VJ, Sasamura H, Hein L ART
Yr: 1993 Vol: 11 Nbr: 3 Abs: Pg: S13-S18

Shear stress elevates endothelial cGMP: role of a potassium channel and G protein coupling
Periodical: Circulation Index Medicus:
Authors: Ohno M, Gibbons GH, Dzau VJ, Cooke JP ART
Yr: 1993 Vol: 88 Nbr: 1 Abs: Pg: 193-197

Importance of tissue angiotensin converting enzyme inhibition in preventing neointima formation
Periodical: Circulation Index Medicus:
Authors: Rakugi H, Wang D, Dzau VJ, Pratt RE ART
Yr: 0 Vol: Nbr: Abs: Pg:

Distinct nuclear proteins competing for an overlapping sequence of cAMP and negative-regulatory elements regulate tissue-specific mouse renin gene expression
Periodical: Journal of Clinical Investigation Index Medicus:
Authors: Horiuchi M, Pratt RE, Nakamura N, Dzau VJ ART
Yr: 0 Vol: Nbr: Abs: Pg: