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Randolph Hastings, M.D., Ph.D.

Veterans Medical Research Foundation # of Grants: 2

Grants

Novel regulatory mechanisms for lung cancer growth 2000 (Cycle 9) $100,000
Cancer Research Project Awards

Novel regulatory mechanisms for lung cancer growth 2001 (Cycle 10) $620,032
Cancer Research Project Awards
Publications

Parathyroid hormone-related protein regulates growth of orthotopic human lung tumors in athymic mice
Periodical: Cancer Index Medicus:
Authors: Hastings RH, Burton DW, Quintana RA, Biederman E, Gujral A, Deftos LJ ART
Yr: 0 Vol: Nbr: Abs: Pg:

Parathyroid hormone-related protein regulates the growth of orthotopic human lung tumors in athymic mice.
Periodical: Cancer Index Medicus:
Authors: Hastings RH, Burton DW, Quintana RA, Biederman E, Guijral A, and Deftos LJ ART
Yr: 2001 Vol: 92 Nbr: 6 Abs: Pg: 1402-1410

thyroid hormone-related protein response to hyperoxic lung injury.
Periodical: American Journal of Physiology. Lung Cell Molecular Physiology. Index Medicus:
Authors: Hastings RH, Ryan RM, D'Angio CT, Holm BA, Patel A, Quintana R, Biederman E, et al. ART
Yr: 2002 Vol: 282 Nbr: Abs: Pg: L1198-L1208

Parathyroid hormone-related protein 38-64 regulates lung cell proliferation after silica injury.
Periodical: American Journal of Physiology. Lung Cell Molecular Physiology. Index Medicus:
Authors: Hastings RH, Asirvatham A, Quintana R, Sandoval R, Dutta R, Burton DW, Deftos LJ ART
Yr: 2002 Vol: 283 Nbr: Abs: Pg: L12-L21

Role of parathyroid hormone-related protein in lung cancer cell survival.
Periodical: Chest Index Medicus:
Authors: Hastings RH, Araiza F, Burton DW, Deftos LJ ART
Yr: 2004 Vol: 125 Nbr: Abs: Pg: 150S

Pro-apoptotic effects of parathyroid hormon-related protein in type II pneumocytes.
Periodical: American Journal of Physiology. Lung Cell Molecular Physiology. Index Medicus:
Authors: Hastings RH ART
Yr: 0 Vol: Nbr: Abs: Pg:

Mechanisms of in vivo alveolar protein clearance.
Periodical: American Journal of Physiology Index Medicus:
Authors: Hastings RH, Folkesson HG, Matthay MA ART
Yr: 0 Vol: Nbr: Abs: Pg:

Proteolysis of ProPTHrP(1-141) by prohormone thiol protease (PTP) at multibasic residues generates PTHrP-related peptides: Implications for PTHrP peptide production in lung cancer cells.
Periodical: Biochemistry and Biophysics Research Communications Index Medicus:
Authors: Hook VYH, Burton DW, Yasothornsrikul S, Hastings RH, Deftos IJ ART
Yr: 2001 Vol: 285 Nbr: Abs: Pg: 932-938

Comparative tissue distribution of the processing enzymes prohormone thoil protease, and prohormone convertases 1 and 2, in human PTHrP-producing cell lines and mammalian neuroendocrine tissues.
Periodical: Endocrine Index Medicus:
Authors: Deftos IJ, Burton DW, Hastings RH, Terkeltaub R, Hook VYH ART
Yr: 2001 Vol: 15 Nbr: 2 Abs: Pg: 217-224

Parathyroid hormone-related protein ameliorates death receptormediated apoptosis in lung cancer cells.
Periodical: American journal of physiology. Cell physiology Index Medicus:
Authors: Hastings RH, Araiza F, Burton DW, Zhang L, Bedley M, Deftos IJ ART
Yr: 2003 Vol: 285 Nbr: 6 Abs: Pg: C1429-1436

Parathyroid hormone-related protein regulates apoptosis in lung cancer cells through protein kinase A.
Periodical: American journal of physiology. Cell physiology Index Medicus:
Authors: Hastings RH, Araiza F. Burton DW, Bedley M, Deftos IJ ART
Yr: 2004 Vol: 287 Nbr: 6 Abs: Pg: C1616-C1622

Monitoring of skeletal progression of prostate cancer by GFP imaging x-ray, and serum OPG and PTHrP.
Periodical: Prostate Index Medicus:
Authors: Burton DW, Geller J, Yang M, Jiang P, Barken I, Hastings RH, Hoffman RM, et al. ART
Yr: 2004 Vol: Nbr: Abs: Pg:

Parathyroid hormone-related protein and lung biology.
Periodical: Respiratory Physiological Neurobiological Index Medicus:
Authors: Hastings RH ART
Yr: 2004 Vol: 142 Nbr: 2 - 3 Abs: Pg: 95-113

Apoptotic effects of parathyroid hormone related protein in prostate cancer cells.
Periodical: Journal of Bone & Mineral Research Program and Abstracts Index Medicus:
Authors: Matheshwari VV, Burton DW, Hastings RH, Aguilera JA, Pardo FS, Deftos IJ ART
Yr: 2003 Vol: 18 Nbr: Suppl 2 Abs: Pg: S199

Parathyroid hormone-related protein promotes lung cancer cell survival.
Periodical: Journal of Bone & Mineral Research Program and Abstracts Index Medicus:
Authors: Hastings RH, Araiza F, Burton DW, Deftos IJ ART
Yr: 2003 Vol: 18 Nbr: Suppl 2 Abs: Pg: S113

PTHrP mediates apoptosis resistance in lung cancer cells through PKA-dependent pathways.
Periodical: American Journal of Respiratory and Critical Care Medicine Index Medicus:
Authors: Hastings R, Araiza F, Bedley M, Burton D, Deftos L ART
Yr: 2004 Vol: 169 Nbr: 7 Abs: Pg: A239