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Roles of Hypoxia, Nicotine & cAMP in Ischemic Heart Failure

Institution: SRI International
Investigator(s): Keith Webster, Ph.D.
Award Cycle: 1992 (Cycle 1) Grant #: 1RT-0402 Award: $713,367
Subject Area: Cardiovascular Disease
Award Type: Research Project Awards
Abstracts
Publications

Molecular regulation of cardiac myocyte adaptations to chronic hypoxia
Periodical: Index Medicus:
Authors: Webster KA, Bishopric NH ART
Yr: 1992 Vol: 24 Nbr: Abs: Pg:

Molecular regulation of cardiac myocyte adaptations to chronic hypoxia
Periodical: Journal of Molecular and Cellular Cardiology Index Medicus:
Authors: Webster KA, Bishropic NH ART
Yr: 1992 Vol: 24 Nbr: 7 Abs: Pg: 741-751

beta-adrenergic regulation of a myocardial actin gene through a cyclic AMP-independent pathway
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Bishropic NH, Sato B, Webster KA ART
Yr: 1992 Vol: 267 Nbr: 29 Abs: Pg: 20932-20944

Positive regulation of the skeletal alpha-actin gene by fos and jun in cardiac myocytes
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Bishopric NH, Jayasena V, Webster KA ART
Yr: 1992 Vol: 267 Nbr: 35 Abs: Pg: 2567-2573

Induction and nuclear accumulation of fos and jun proto-oncogenes in hypoxic cardiac myocytes
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Webster KA, Discher JD, Bishopric NH ART
Yr: 1993 Vol: 268 Nbr: 22 Abs: Pg: 16852-16859

Abnormal calcium handling and negative lusitropy in hypoxic cardiac myocytes exposed to the calcium sensitizer EMD 53998
Periodical: Journal of Molecular and Cellular Cardiology Index Medicus:
Authors: Webster KA, Bodi I, McNamara JP, Tracy M, Bishopric NH ART
Yr: 1993 Vol: 25 Nbr: 7 Abs: Pg: 747-751

Induction of proto-oncogenes and lipid second messengers in hypoxic cardiac myocytes
Periodical: Proceedings of the International Hypoxia Symposium Index Medicus:
Authors: Webster KA, Discher JD, Bishopric NH ART
Yr: 1993 Vol: Nbr: Abs: Pg:

Fos and jun regulate preferential induction of the skeletal alpha-actin gene in neonatal rat myocardial cells
Periodical: Circulation Index Medicus:
Authors: Bishopric NH, Webster KA ABS
Yr: 1991 Vol: 84 Nbr: Suppl II Abs: Pg: 87

Calcium, but not cAMP or contracility, mediates beta-adenergic induction of the skeletal alpha-actin gene in cultured heart muscle cells
Periodical: Circulation Index Medicus:
Authors: Bishopric NH, Webster KA ABS
Yr: 1991 Vol: 84 Nbr: Suppl II Abs: Pg: 87

Accumulation of mono- and diacylglycerols precedes induction of proto-oncogenes fos and jun in hypoxic cardiac myocytes
Periodical: Circulation Index Medicus:
Authors: Webster KA, Discher D, Bishopric N ABS
Yr: 1992 Vol: 86 Nbr: Suppl I Abs: Pg: 625

Compartmentalized calcium and calcium sensitizers regulate induction of myocardial genes during beta-adrenoceptor-mediated hypertrophy
Periodical: Journal of Cellular Biochemistry. Supplement Index Medicus:
Authors: Bishopric NH, Sato B, Webster KA ABS
Yr: 1993 Vol: 17D Nbr: Abs: Pg: 237

Induction of immediate-early genes and hypertrophic marker transcripts by hypoxia-reoxygenation cycles in rodent cardiac myocytes
Periodical: Journal of Cellular Biochemistry. Supplement Index Medicus:
Authors: Webster KA, Discher D, Sato B, Bodi I, Bishopric NH ABS
Yr: 1993 Vol: 17D Nbr: Abs: Pg: 237

Enhanced effectiveness of HVJ mediated gene transfer into cultured rat neonatal cardiac myocytes
Periodical: Circulation Index Medicus:
Authors: Ellison K, Bishopric N, Webster K, et al ABS
Yr: 1993 Vol: Nbr: Abs: Pg: