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Roles of Hypoxia, Nicotine, & Camp in Ischemic Heart Failure

Institution: SRI International
Investigator(s): Keith Webster, Ph.D.
Award Cycle: 1995 (Cycle 4) Grant #: 4RT-0134 Award: $746,727
Subject Area: Cardiovascular Disease
Award Type: Research Project Awards
Abstracts
Publications

Regulation of fos and jun immediate-early genes by redox or metabolic stress in cardiac myocytes
Periodical: Circulation Research Index Medicus:
Authors: Webster KA, Discher DJ, Bishopric NH ART
Yr: 1994 Vol: 74 Nbr: 4 Abs: Pg: 679-686

Cardioprotection in an in vitro model of hypoxic preconditioning
Periodical: Journal of Molecular and Cellular Cardiology Index Medicus:
Authors: Webster KA, Discher DJ, Bishropic NH ART
Yr: 1995 Vol: 27 Nbr: 1 Abs: Pg: 453-458

Zinc fingers are redox sensors during acute oxidative stress
Periodical: Circulation Index Medicus:
Authors: Wu X, Discher DJ, Bishropic NH, Webster KA ABS
Yr: 1994 Vol: 90 Nbr: Abs: Pg: I-250

Adenovirus E1A 12S protein selectively inhibits cardiac myocyte-specific gene expression
Periodical: Circulation Index Medicus:
Authors: Bishropic NH, Sato B, Webster KA ABS
Yr: 1994 Vol: 90 Nbr: Abs: Pg: I-196

Functional regulation of zinc finger transcription factors by redox stress in vivo
Periodical: Journal of Cellular Biochemistry. Supplement Index Medicus:
Authors: Wu X, Discher DJ, Bishropic NH, Webster KA ABS
Yr: 1995 Vol: 21A Nbr: Abs: Pg: 263

Redox regulation of the endothelin gene: mechanism and tissue specificity
Periodical: Journal of Cellular Biochemistry. Supplement Index Medicus:
Authors: Webster KA, Bodi I, Discher DJ, Bishropic NH ABS
Yr: 1995 Vol: 21A Nbr: Abs: Pg: 257

Induced activity of the skeletal actin promoter in ischemic reperfused myocardium
Periodical: Journal of Molecular and Cellular Cardiology Index Medicus:
Authors: McDonald P, Hicks MN, Webster KA, et al ABS
Yr: 1995 Vol: Nbr: Abs: Pg:

Cell-specificity and signaling pathway of endothelin-1 gene regulation by hypoxia
Periodical: Cardiovascular Research Index Medicus:
Authors: Bodi I, Bishopric NH, Discher DJ, Wu XS, Webster KA ART
Yr: 1995 Vol: 30 Nbr: Abs: Pg: 975-984

Physical and functional sensitivity of zinc finger transcription factors to redox change
Periodical: Molecular and Cellular Biology Index Medicus:
Authors: Wu XS, Bishopric NH, Discher DJ, Murphy BJ, Webster KA ART
Yr: 1996 Vol: 16 Nbr: 3 Abs: Pg: 1035-1046

Identification of a redox response element in the proximal promoters of muscle specific lycolytic enzyme genes
Periodical: Circulation Index Medicus:
Authors: Webster KA, Discher DJ, Wu X, Peterson CA, Bishopric NH ABS
Yr: 1995 Vol: 92 Nbr: Abs: Pg: I755-I756

Hypoxia regulated vectors for targeting genes to ischemic myocardium
Periodical: Circulation Index Medicus:
Authors: Webster KA, Wu X, Prentice H, et al ABS
Yr: 1995 Vol: 92 Nbr: Abs: Pg: I756

Induction of stress response and hypertrophy-related genes by the positive inotrope, calcium sensitizing agents EMD53998, Levosimendam, and Pimobendan in heart cells
Periodical: Circulation Index Medicus:
Authors: Webster KA, Bodi I, Sato B, Discher DJ, Bishopric NH ABS
Yr: 1995 Vol: 92 Nbr: Abs: Pg: I43

E1A inhibits cardiac-specific transcription independently of p300 and pRb
Periodical: Circulation Index Medicus:
Authors: Zeng Q-G, Webster KA, Sato B, Bishopric NH ABS
Yr: 1995 Vol: 92 Nbr: Abs: Pg: I755