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Roles of Hypoxia, Nicotine, & Camp in Ischemic Heart Failure

Institution:	SRI International
Investigator(s):	Keith Webster, Ph.D.
Award Cycle:	1995 (Cycle 4)	Grant #: 4RT-0134	Award: $746,727
Subject Area:	Cardiovascular Disease
Award Type:	Research Project Awards

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Regulation of fos and jun immediate-early genes by redox or metabolic stress in cardiac myocytes
Periodical: Circulation Research			Index Medicus:
Authors: Webster KA, Discher DJ, Bishopric NH				ART
Yr: 1994	Vol: 74	Nbr: 4	Abs:	Pg: 679-686

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Cardioprotection in an in vitro model of hypoxic preconditioning
Periodical: Journal of Molecular and Cellular Cardiology			Index Medicus:
Authors: Webster KA, Discher DJ, Bishropic NH				ART
Yr: 1995	Vol: 27	Nbr: 1	Abs:	Pg: 453-458

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Zinc fingers are redox sensors during acute oxidative stress
Periodical: Circulation			Index Medicus:
Authors: Wu X, Discher DJ, Bishropic NH, Webster KA				ABS
Yr: 1994	Vol: 90	Nbr:	Abs:	Pg: I-250

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Adenovirus E1A 12S protein selectively inhibits cardiac myocyte-specific gene expression
Periodical: Circulation			Index Medicus:
Authors: Bishropic NH, Sato B, Webster KA				ABS
Yr: 1994	Vol: 90	Nbr:	Abs:	Pg: I-196

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Functional regulation of zinc finger transcription factors by redox stress in vivo
Periodical: Journal of Cellular Biochemistry. Supplement			Index Medicus:
Authors: Wu X, Discher DJ, Bishropic NH, Webster KA				ABS
Yr: 1995	Vol: 21A	Nbr:	Abs:	Pg: 263

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Redox regulation of the endothelin gene: mechanism and tissue specificity
Periodical: Journal of Cellular Biochemistry. Supplement			Index Medicus:
Authors: Webster KA, Bodi I, Discher DJ, Bishropic NH				ABS
Yr: 1995	Vol: 21A	Nbr:	Abs:	Pg: 257

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Induced activity of the skeletal actin promoter in ischemic reperfused myocardium
Periodical: Journal of Molecular and Cellular Cardiology			Index Medicus:
Authors: McDonald P, Hicks MN, Webster KA, et al				ABS
Yr: 1995	Vol:	Nbr:	Abs:	Pg:

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Cell-specificity and signaling pathway of endothelin-1 gene regulation by hypoxia
Periodical: Cardiovascular Research			Index Medicus:
Authors: Bodi I, Bishopric NH, Discher DJ, Wu XS, Webster KA				ART
Yr: 1995	Vol: 30	Nbr:	Abs:	Pg: 975-984

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Physical and functional sensitivity of zinc finger transcription factors to redox change
Periodical: Molecular and Cellular Biology			Index Medicus:
Authors: Wu XS, Bishopric NH, Discher DJ, Murphy BJ, Webster KA				ART
Yr: 1996	Vol: 16	Nbr: 3	Abs:	Pg: 1035-1046

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Identification of a redox response element in the proximal promoters of muscle specific lycolytic enzyme genes
Periodical: Circulation			Index Medicus:
Authors: Webster KA, Discher DJ, Wu X, Peterson CA, Bishopric NH				ABS
Yr: 1995	Vol: 92	Nbr:	Abs:	Pg: I755-I756

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Hypoxia regulated vectors for targeting genes to ischemic myocardium
Periodical: Circulation			Index Medicus:
Authors: Webster KA, Wu X, Prentice H, et al				ABS
Yr: 1995	Vol: 92	Nbr:	Abs:	Pg: I756

---

Induction of stress response and hypertrophy-related genes by the positive inotrope, calcium sensitizing agents EMD53998, Levosimendam, and Pimobendan in heart cells
Periodical: Circulation			Index Medicus:
Authors: Webster KA, Bodi I, Sato B, Discher DJ, Bishopric NH				ABS
Yr: 1995	Vol: 92	Nbr:	Abs:	Pg: I43

---

E1A inhibits cardiac-specific transcription independently of p300 and pRb
Periodical: Circulation			Index Medicus:
Authors: Zeng Q-G, Webster KA, Sato B, Bishopric NH				ABS
Yr: 1995	Vol: 92	Nbr:	Abs:	Pg: I755

---

Regulation of fos and jun immediate-early genes by redox or metabolic stress in cardiac myocytes
Periodical: Circulation Research			Index Medicus:
Authors: Webster KA, Discher DJ, Bishopric NH				ART
Yr: 1994	Vol: 74	Nbr: 4	Abs:	Pg: 679-686

---

Cardioprotection in an in vitro model of hypoxic preconditioning
Periodical: Journal of Molecular and Cellular Cardiology			Index Medicus:
Authors: Webster KA, Discher DJ, Bishropic NH				ART
Yr: 1995	Vol: 27	Nbr: 1	Abs:	Pg: 453-458

---

Zinc fingers are redox sensors during acute oxidative stress
Periodical: Circulation			Index Medicus:
Authors: Wu X, Discher DJ, Bishropic NH, Webster KA				ABS
Yr: 1994	Vol: 90	Nbr:	Abs:	Pg: I-250

---

Adenovirus E1A 12S protein selectively inhibits cardiac myocyte-specific gene expression
Periodical: Circulation			Index Medicus:
Authors: Bishropic NH, Sato B, Webster KA				ABS
Yr: 1994	Vol: 90	Nbr:	Abs:	Pg: I-196

---

Functional regulation of zinc finger transcription factors by redox stress in vivo
Periodical: Journal of Cellular Biochemistry. Supplement			Index Medicus:
Authors: Wu X, Discher DJ, Bishropic NH, Webster KA				ABS
Yr: 1995	Vol: 21A	Nbr:	Abs:	Pg: 263

---

Redox regulation of the endothelin gene: mechanism and tissue specificity
Periodical: Journal of Cellular Biochemistry. Supplement			Index Medicus:
Authors: Webster KA, Bodi I, Discher DJ, Bishropic NH				ABS
Yr: 1995	Vol: 21A	Nbr:	Abs:	Pg: 257

---

Induced activity of the skeletal actin promoter in ischemic reperfused myocardium
Periodical: Journal of Molecular and Cellular Cardiology			Index Medicus:
Authors: McDonald P, Hicks MN, Webster KA, et al				ABS
Yr: 1995	Vol:	Nbr:	Abs:	Pg:

---

Cell-specificity and signaling pathway of endothelin-1 gene regulation by hypoxia
Periodical: Cardiovascular Research			Index Medicus:
Authors: Bodi I, Bishopric NH, Discher DJ, Wu XS, Webster KA				ART
Yr: 1995	Vol: 30	Nbr:	Abs:	Pg: 975-984

---

Physical and functional sensitivity of zinc finger transcription factors to redox change
Periodical: Molecular and Cellular Biology			Index Medicus:
Authors: Wu XS, Bishopric NH, Discher DJ, Murphy BJ, Webster KA				ART
Yr: 1996	Vol: 16	Nbr: 3	Abs:	Pg: 1035-1046

---

Identification of a redox response element in the proximal promoters of muscle specific lycolytic enzyme genes
Periodical: Circulation			Index Medicus:
Authors: Webster KA, Discher DJ, Wu X, Peterson CA, Bishopric NH				ABS
Yr: 1995	Vol: 92	Nbr:	Abs:	Pg: I755-I756

---

Hypoxia regulated vectors for targeting genes to ischemic myocardium
Periodical: Circulation			Index Medicus:
Authors: Webster KA, Wu X, Prentice H, et al				ABS
Yr: 1995	Vol: 92	Nbr:	Abs:	Pg: I756

---

Induction of stress response and hypertrophy-related genes by the positive inotrope, calcium sensitizing agents EMD53998, Levosimendam, and Pimobendan in heart cells
Periodical: Circulation			Index Medicus:
Authors: Webster KA, Bodi I, Sato B, Discher DJ, Bishopric NH				ABS
Yr: 1995	Vol: 92	Nbr:	Abs:	Pg: I43

---

E1A inhibits cardiac-specific transcription independently of p300 and pRb
Periodical: Circulation			Index Medicus:
Authors: Zeng Q-G, Webster KA, Sato B, Bishopric NH				ABS
Yr: 1995	Vol: 92	Nbr:	Abs:	Pg: I755

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