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Michael Karin, Ph.D.

University of California, San Diego

# of Grants: 2

Effects of Tobacco Smoke on Proto-Oncogene Activity	1994 (Cycle 3)	$382,758
Cancer	Research Project Awards
NF-kB mediated inflammation in tobacco-induced lung cancer	2006 (Cycle 15)	$420,000
Cancer	Research Project Awards

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Identification of an oncoprotein- and UV- responsive protein kinase that binds and potentiates the c-Jun activation domain
Periodical: Genes and Development			Index Medicus:
Authors: Hibi M, Lin A, Smeal T, Minden A, Karin M				ART
Yr: 1993	Vol: 7	Nbr: 11	Abs:	Pg: 2135-2148

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c_jun activation domain
Periodical: Cell			Index Medicus:
Authors: Derijard B, Hibi M, Wu I-H, et al				ART
Yr: 1994	Vol: 76	Nbr: 6	Abs:	Pg: 1025-1037

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JNK is involved in signal integration during costimulation of T lymphocytes
Periodical: Cell			Index Medicus:
Authors: Su B, Jacinto E, Hibi M, Kallunki T, Karin M, Ben-Neriah Y				ART
Yr: 1994	Vol: 77	Nbr: 5	Abs:	Pg: 727-736

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JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation
Periodical: Genes and Development			Index Medicus:
Authors: Kallunki T, Su B, Tsigelny I, Sluss HK, et al				ART
Yr: 1994	Vol: 8	Nbr: 24	Abs:	Pg: 2996-3007

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Induction of c-fos expression through JNK mediated TCF/Elk-1 phosphorylation
Periodical: Embo Journal			Index Medicus:
Authors: Cavigelli M, Fabrizio D, Claret F-X, Karin M				ART
Yr: 1995	Vol:	Nbr:	Abs:	Pg:

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c-fos transcriptional activity stimulated by Ha-Ras-activated protein kinase distinct from JNK and ERK
Periodical: Nature			Index Medicus:
Authors: Deng T, Karin M				ART
Yr: 1994	Vol: 371	Nbr: 6493	Abs:	Pg: 171-175

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Identification of a dual specificity kinase that activates the Jun kinases and p38-MpK2
Periodical: Science			Index Medicus:
Authors: Lin A, Minden A, Martinetto H, et al				ART
Yr: 1995	Vol: 268	Nbr: 5208	Abs:	Pg: 286-290

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Anti-tumor promotion by phenolic antioxidants: inhibition of AP-1 activity through induction of Fra expression
Periodical: Proceedings of the National Academy of Sciences of the United States of America			Index Medicus:
Authors: Yoshioka K, Deng T, Cavigelli M, Karin M				ART
Yr: 1995	Vol: 92	Nbr: 11	Abs:	Pg: 4972-4976

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Identification of an oncoprotein- and UV- responsive protein kinase that binds and potentiates the c-Jun activation domain
Periodical: Genes and Development			Index Medicus:
Authors: Hibi M, Lin A, Smeal T, Minden A, Karin M				ART
Yr: 1993	Vol: 7	Nbr: 11	Abs:	Pg: 2135-2148

---

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c_jun activation domain
Periodical: Cell			Index Medicus:
Authors: Derijard B, Hibi M, Wu I-H, et al				ART
Yr: 1994	Vol: 76	Nbr: 6	Abs:	Pg: 1025-1037

---

JNK is involved in signal integration during costimulation of T lymphocytes
Periodical: Cell			Index Medicus:
Authors: Su B, Jacinto E, Hibi M, Kallunki T, Karin M, Ben-Neriah Y				ART
Yr: 1994	Vol: 77	Nbr: 5	Abs:	Pg: 727-736

---

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation
Periodical: Genes and Development			Index Medicus:
Authors: Kallunki T, Su B, Tsigelny I, Sluss HK, et al				ART
Yr: 1994	Vol: 8	Nbr: 24	Abs:	Pg: 2996-3007

---

Induction of c-fos expression through JNK mediated TCF/Elk-1 phosphorylation
Periodical: Embo Journal			Index Medicus:
Authors: Cavigelli M, Fabrizio D, Claret F-X, Karin M				ART
Yr: 1995	Vol:	Nbr:	Abs:	Pg:

---

c-fos transcriptional activity stimulated by Ha-Ras-activated protein kinase distinct from JNK and ERK
Periodical: Nature			Index Medicus:
Authors: Deng T, Karin M				ART
Yr: 1994	Vol: 371	Nbr: 6493	Abs:	Pg: 171-175

---

Identification of a dual specificity kinase that activates the Jun kinases and p38-MpK2
Periodical: Science			Index Medicus:
Authors: Lin A, Minden A, Martinetto H, et al				ART
Yr: 1995	Vol: 268	Nbr: 5208	Abs:	Pg: 286-290

---

Anti-tumor promotion by phenolic antioxidants: inhibition of AP-1 activity through induction of Fra expression
Periodical: Proceedings of the National Academy of Sciences of the United States of America			Index Medicus:
Authors: Yoshioka K, Deng T, Cavigelli M, Karin M				ART
Yr: 1995	Vol: 92	Nbr: 11	Abs:	Pg: 4972-4976

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The p53-regulated sestrin gene products inhibit in TOR signaling.
Periodical: Cell			Index Medicus:
Authors: Budanov AV, Karin M				ART
Yr: 2008	Vol: 134	Nbr:	Abs:	Pg: 451-460

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Carcinoma produced factors activate myeloid cells via TLR2 to stimulate metastasis.
Periodical: Nature			Index Medicus:
Authors: Kim S, Takahashi H, Lin W, Descargues P, Grivennikov S, Kim Y, Luo J, Karin M.				ART
Yr: 2009	Vol: 457	Nbr:	Abs:	Pg: 102-106

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The p53-regulated sestrin gene products inhibit in TOR signaling.
Periodical: Cell			Index Medicus:
Authors: Budanov AV, Karin M				ART
Yr: 2008	Vol: 134	Nbr:	Abs:	Pg: 451-460

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Carcinoma produced factors activate myeloid cells via TLR2 to stimulate metastasis.
Periodical: Nature			Index Medicus:
Authors: Kim S, Takahashi H, Lin W, Descargues P, Grivennikov S, Kim Y, Luo J, Karin M.				ART
Yr: 2009	Vol: 457	Nbr:	Abs:	Pg: 102-106

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