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Christopher Glembotski, Ph.D.

San Diego State University Research Foundation

# of Grants: 1

Mechanism of Endothelin-Stimulated ANF Secretion	1992 (Cycle 1)	$447,480
Cardiovascular Disease	Research Project Awards

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Studies of the hormonal regulation of cellular location of ANF processing and the mechanisms of phenylephrine-, endothelin-, and potassium chloride-stimulated ANF secretion using a primary cardiocyte culture model
Periodical: Canadian Journal of Physiology and Pharmacology			Index Medicus:
Authors: Glembotski CC, Irons CE, Sprenkle AB, et al.				ART
Yr: 0	Vol:	Nbr:	Abs:	Pg:

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The alpha-adrenergic stimulation of ANF expression in cardiac myocytes requires calcium influx, protein kinase C, and calmodulin-regulated pathways
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Sei CA, Irons CE, Sprenkle AB, et al.				ART
Yr: 0	Vol:	Nbr:	Abs:	Pg:

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Regulation of ANF gene expression in cardiac myocytes
Periodical: Circulation			Index Medicus:
Authors: Sprenkle AB, Glembotski CC				ART
Yr: 1991	Vol:	Nbr:	Abs:	Pg:

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Gene expression and ANF processing and secretion in cultured AT-1 cardiac myocytes
Periodical: Circulation			Index Medicus:
Authors: Lanson NA, Glembotski CC, Steinhelper ME, Field LJ, Claycomb WC				ART
Yr: 1992	Vol: 85	Nbr: 5	Abs:	Pg: 1835-1841

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Induction of atrial natriuretic factor and myosin light chain-2 gene expression in cultured ventricular myocytes by electrical stimulation of contraction
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: McDonough PM, Glembotski CC				ART
Yr: 1992	Vol: 267	Nbr:	Abs:	Pg:

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The cosecretional maturation by atrial natriuretic factor by primary atrial myocytes
Periodical: Molecular Endocrinology			Index Medicus:
Authors: Sei CA, Hand GL, Murray SF, Glembotski CC				ART
Yr: 1992	Vol: 6	Nbr: 3	Abs:	Pg: 309-319

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Protein kinase C and calmodulin kinase are required for endothelin-stimulated atrial natriuretic factor secretion from primary atrial myocytes
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Irons CE, Sei CA, Hidaka H, Glembotski CC				ART
Yr: 1992	Vol: 267	Nbr: 8	Abs:	Pg: 5211-5216

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The alpha-adrenergic stimulation of atrial natriuretic factor expression in cardiac myocytes regulates calcium influx, protein kinase C and clamodulin-regulated pathways
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Sei CA, Irons CE, Sprenkle AB, McDonough PM, Brown JH, Glembotski CC				ART
Yr: 1991	Vol: 266	Nbr: 24	Abs:	Pg: 15910-15916

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Studies of ANF processing and secretion using a primary cardiocyte culture model
Periodical: Canadian Journal of Physiology and Pharmacology			Index Medicus:
Authors: Glembotski CC, Irons CE, Sprenkle SB, Sei CA				ART
Yr: 1991	Vol: 69	Nbr: 10	Abs:	Pg: 1525-1536

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Regulated secretion of ANF from cultured ventricular myocytes
Periodical: American Journal of Physiology			Index Medicus:
Authors: Irons CE, Sei CA, Glembotski CC				ART
Yr: 1993	Vol: 264	Nbr: 1 Pt 2	Abs:	Pg: H282-H285

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Phenylephrine and endothelin differentially stimulate cardiac phosphoinositide hydrolysis and ANF expression
Periodical: American Journal of Physiology			Index Medicus:
Authors: McDonough PM, Brown JH, Glembotski CC				ART
Yr: 1993	Vol: 264	Nbr: 2 Pt 2	Abs:	Pg: H625-H630

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Induction of atrial natriuretic factor and myosin light chain-2 gene expression in cultured ventricular myocytes by electrical stimulation of contraction
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: McDonough PM, Glembotski CC				ART
Yr: 1992	Vol: 267	Nbr: 17	Abs:	Pg: 11665-11668

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Identification of the receptor subtype responsible for endothelin-mediated protein kinase C activation and atrial natriuretic factor secretion from atrial myocytes
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Irons CE, Murray SF, Glembotski CC				ART
Yr: 1993	Vol: 268	Nbr: 31	Abs:	Pg: 23417-23421

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Myocardial alpha-thrombin receptor activation induces hypertrophy and increases atrial natriuretic factor gene expression
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Glembotski CC, Irons CE, Krown KA, Murray SF, Sprenkle AB, Sei CA				ART
Yr: 1993	Vol: 268	Nbr: 27	Abs:	Pg: 20646-20652

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Involvement of cytoplasmic calcium and protein kinases in the regulation of atrial natriuretic factor secretion by contraction rate and endothelin
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: McDonough PM, Stella SL, Glembotski CC				ART
Yr: 1994	Vol: 269	Nbr: 13	Abs:	Pg: 9466-9472

---

Studies of the hormonal regulation of cellular location of ANF processing and the mechanisms of phenylephrine-, endothelin-, and potassium chloride-stimulated ANF secretion using a primary cardiocyte culture model
Periodical: Canadian Journal of Physiology and Pharmacology			Index Medicus:
Authors: Glembotski CC, Irons CE, Sprenkle AB, et al.				ART
Yr: 0	Vol:	Nbr:	Abs:	Pg:

---

The alpha-adrenergic stimulation of ANF expression in cardiac myocytes requires calcium influx, protein kinase C, and calmodulin-regulated pathways
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Sei CA, Irons CE, Sprenkle AB, et al.				ART
Yr: 0	Vol:	Nbr:	Abs:	Pg:

---

Regulation of ANF gene expression in cardiac myocytes
Periodical: Circulation			Index Medicus:
Authors: Sprenkle AB, Glembotski CC				ART
Yr: 1991	Vol:	Nbr:	Abs:	Pg:

---

Gene expression and ANF processing and secretion in cultured AT-1 cardiac myocytes
Periodical: Circulation			Index Medicus:
Authors: Lanson NA, Glembotski CC, Steinhelper ME, Field LJ, Claycomb WC				ART
Yr: 1992	Vol: 85	Nbr: 5	Abs:	Pg: 1835-1841

---

Induction of atrial natriuretic factor and myosin light chain-2 gene expression in cultured ventricular myocytes by electrical stimulation of contraction
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: McDonough PM, Glembotski CC				ART
Yr: 1992	Vol: 267	Nbr:	Abs:	Pg:

---

The cosecretional maturation by atrial natriuretic factor by primary atrial myocytes
Periodical: Molecular Endocrinology			Index Medicus:
Authors: Sei CA, Hand GL, Murray SF, Glembotski CC				ART
Yr: 1992	Vol: 6	Nbr: 3	Abs:	Pg: 309-319

---

Protein kinase C and calmodulin kinase are required for endothelin-stimulated atrial natriuretic factor secretion from primary atrial myocytes
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Irons CE, Sei CA, Hidaka H, Glembotski CC				ART
Yr: 1992	Vol: 267	Nbr: 8	Abs:	Pg: 5211-5216

---

The alpha-adrenergic stimulation of atrial natriuretic factor expression in cardiac myocytes regulates calcium influx, protein kinase C and clamodulin-regulated pathways
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Sei CA, Irons CE, Sprenkle AB, McDonough PM, Brown JH, Glembotski CC				ART
Yr: 1991	Vol: 266	Nbr: 24	Abs:	Pg: 15910-15916

---

Studies of ANF processing and secretion using a primary cardiocyte culture model
Periodical: Canadian Journal of Physiology and Pharmacology			Index Medicus:
Authors: Glembotski CC, Irons CE, Sprenkle SB, Sei CA				ART
Yr: 1991	Vol: 69	Nbr: 10	Abs:	Pg: 1525-1536

---

Regulated secretion of ANF from cultured ventricular myocytes
Periodical: American Journal of Physiology			Index Medicus:
Authors: Irons CE, Sei CA, Glembotski CC				ART
Yr: 1993	Vol: 264	Nbr: 1 Pt 2	Abs:	Pg: H282-H285

---

Phenylephrine and endothelin differentially stimulate cardiac phosphoinositide hydrolysis and ANF expression
Periodical: American Journal of Physiology			Index Medicus:
Authors: McDonough PM, Brown JH, Glembotski CC				ART
Yr: 1993	Vol: 264	Nbr: 2 Pt 2	Abs:	Pg: H625-H630

---

Induction of atrial natriuretic factor and myosin light chain-2 gene expression in cultured ventricular myocytes by electrical stimulation of contraction
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: McDonough PM, Glembotski CC				ART
Yr: 1992	Vol: 267	Nbr: 17	Abs:	Pg: 11665-11668

---

Identification of the receptor subtype responsible for endothelin-mediated protein kinase C activation and atrial natriuretic factor secretion from atrial myocytes
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Irons CE, Murray SF, Glembotski CC				ART
Yr: 1993	Vol: 268	Nbr: 31	Abs:	Pg: 23417-23421

---

Myocardial alpha-thrombin receptor activation induces hypertrophy and increases atrial natriuretic factor gene expression
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: Glembotski CC, Irons CE, Krown KA, Murray SF, Sprenkle AB, Sei CA				ART
Yr: 1993	Vol: 268	Nbr: 27	Abs:	Pg: 20646-20652

---

Involvement of cytoplasmic calcium and protein kinases in the regulation of atrial natriuretic factor secretion by contraction rate and endothelin
Periodical: Journal of Biological Chemistry			Index Medicus:
Authors: McDonough PM, Stella SL, Glembotski CC				ART
Yr: 1994	Vol: 269	Nbr: 13	Abs:	Pg: 9466-9472

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