Xiao-Kun Zhang, Ph.D.
| The Burnham Institute for Medical Research | # of Grants: 4 |
Grants
| Does nicotine inhibit anticancer activities of Vitamin A? | 1997 (Cycle 6) | $788,808 |
| Cancer | Research Project Awards | |
| Molecular Mechanism of Retinoic Acid Action | 1992 (Cycle 1) | $75,600 |
| General Biomedical Science | Postdoctoral Fellowship Awards | |
| Novel agents for apoptosis of lung cancer | 2002 (Cycle 11) | $787,977 |
| Cancer | Research Project Awards | |
| Vitamin A derivatives as antagonists of nicotine effects | 2004 (Cycle 13) | $670,085 |
| Cancer | Research Project Awards | |
Publications
| Induction of apoptosis by retinoids in human lung cancer cell lines | ||||
| Periodical: International Journal of Cancer | Index Medicus: | |||
| Authors: Li Y, Dawson MI, Lee MO, Jong L, Hobbs PD, Zhang XK | ART | |||
| Yr: 1998 | Vol: 75 | Nbr: | Abs: | Pg: 88-95 |
| Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Li Y, Lin B, Agadir A, Liu R, Dawson MI, Reed JC, Zhang XK | ART | |||
| Yr: 1998 | Vol: 18 | Nbr: | Abs: | Pg: 4719-4731 |
| Interaction of BAG-1 with retinoic acid receptor and its inhibition of retinoic acid-induced apoptosis in cancer cells | ||||
| Periodical: Journal of Biological Chemistry | Index Medicus: | |||
| Authors: Liu R, Takayama S, Zheng Y, et al | ART | |||
| Yr: 1998 | Vol: 273 | Nbr: | Abs: | Pg: 16985-16992 |
| Inhibition of trans-RA-resistant human breast cancer cell growth by retinoid X-receptor-selective retinoids | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Wu Q, Cheng Y, Dawson MI, Hobbs PD, Li Y, Zhang XK | ART | |||
| Yr: 1997 | Vol: 17 | Nbr: | Abs: | Pg: 6598-6608 |
| Activation of three distinct RXR/RAR heterodimers induces growth arrest and differentiation of neuroblastoma cells | ||||
| Periodical: Journal of Biological Chemistry | Index Medicus: | |||
| Authors: Giannini G, Dawson MI, Zhang XK, Thiele CJ | ART | |||
| Yr: 1997 | Vol: 272 | Nbr: | Abs: | Pg: 26693-26701 |
| Conformationally defined retinoic acid analogs: 4 potential new agents for acute promyelocytic and juvenile myelomonocytic leukemias | ||||
| Periodical: Journal of Medicinal Chemistry | Index Medicus: | |||
| Authors: Muccio DD, Brouillette WJ, Breitman TR, et al | ART | |||
| Yr: 1998 | Vol: 41 | Nbr: | Abs: | Pg: 1679-1687 |
| Identification of a novel class of retinoic acid receptor beta-selective retinoid antagonists and their inhibitory effects on AP-1 acitivity and retinoic acid-induced apoptosis in human breast cancer cells | ||||
| Periodical: Journal of Biological Chemistry | Index Medicus: | |||
| Authors: Li Y, Hashimoto Y, Agadir A, Kagechika H, Zhang H-k | ART | |||
| Yr: 1999 | Vol: 274 | Nbr: | Abs: | Pg: 15360-15366 |
| Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3 | ||||
| Periodical: Science | Index Medicus: | |||
| Authors: Li H, Kolluri S, Gu J, et al | ART | |||
| Yr: 2000 | Vol: 289 | Nbr: | Abs: | Pg: 1159-1164 |
| Orphan receptor COUP-TF is required for induction of RARbeta, growth inhibition and apoptosis by retinoic acid in cancer cells | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Lin B, Chen G, Ziao D, et al | ART | |||
| Yr: 2000 | Vol: 20 | Nbr: | Abs: | Pg: 957-970 |
| Unique anti-activator protein-1 activity of retinoic acid receptor beta1 | ||||
| Periodical: Cancer Research | Index Medicus: | |||
| Authors: Lin F, Ziao D, Kolluri S, Zhang X-K | ART | |||
| Yr: 2000 | Vol: 60 | Nbr: | Abs: | Pg: 3271-3280 |
| Regulation of RARbeta expression by RAR- and RXR-selective retinoids in human lung cancer cell lines: effect on growth inhibition and apoptosis induction | ||||
| Periodical: International Journal of Cancer | Index Medicus: | |||
| Authors: Li Y, Dawson MI, Agadir A, et al | ART | |||
| Yr: 1998 | Vol: 75 | Nbr: | Abs: | Pg: 88-95 |
| Differential effect of retinoic acid on growth regulation by phorbol ester in human cancer cell lines | ||||
| Periodical: Journal of Biological Chemistry | Index Medicus: | |||
| Authors: Agadir A, Chen GQ, Bost F, Li Y, Mercola D, Zhang X-K | ART | |||
| Yr: 1999 | Vol: 274 | Nbr: | Abs: | Pg: 29779-29785 |
| Induction of apoptosis by retinoids in human lung cancer cell lines | ||||
| Periodical: International Journal of Cancer | Index Medicus: | |||
| Authors: Li Y, Dawson MI, Lee MO, Jong L, Hobbs PD, Zhang XK | ART | |||
| Yr: 1998 | Vol: 75 | Nbr: | Abs: | Pg: 88-95 |
| Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Li Y, Lin B, Agadir A, Liu R, Dawson MI, Reed JC, Zhang XK | ART | |||
| Yr: 1998 | Vol: 18 | Nbr: | Abs: | Pg: 4719-4731 |
| Interaction of BAG-1 with retinoic acid receptor and its inhibition of retinoic acid-induced apoptosis in cancer cells | ||||
| Periodical: Journal of Biological Chemistry | Index Medicus: | |||
| Authors: Liu R, Takayama S, Zheng Y, et al | ART | |||
| Yr: 1998 | Vol: 273 | Nbr: | Abs: | Pg: 16985-16992 |
| Inhibition of trans-RA-resistant human breast cancer cell growth by retinoid X-receptor-selective retinoids | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Wu Q, Cheng Y, Dawson MI, Hobbs PD, Li Y, Zhang XK | ART | |||
| Yr: 1997 | Vol: 17 | Nbr: | Abs: | Pg: 6598-6608 |
| Activation of three distinct RXR/RAR heterodimers induces growth arrest and differentiation of neuroblastoma cells | ||||
| Periodical: Journal of Biological Chemistry | Index Medicus: | |||
| Authors: Giannini G, Dawson MI, Zhang XK, Thiele CJ | ART | |||
| Yr: 1997 | Vol: 272 | Nbr: | Abs: | Pg: 26693-26701 |
| Conformationally defined retinoic acid analogs: 4 potential new agents for acute promyelocytic and juvenile myelomonocytic leukemias | ||||
| Periodical: Journal of Medicinal Chemistry | Index Medicus: | |||
| Authors: Muccio DD, Brouillette WJ, Breitman TR, et al | ART | |||
| Yr: 1998 | Vol: 41 | Nbr: | Abs: | Pg: 1679-1687 |
| Identification of a novel class of retinoic acid receptor beta-selective retinoid antagonists and their inhibitory effects on AP-1 acitivity and retinoic acid-induced apoptosis in human breast cancer cells | ||||
| Periodical: Journal of Biological Chemistry | Index Medicus: | |||
| Authors: Li Y, Hashimoto Y, Agadir A, Kagechika H, Zhang H-k | ART | |||
| Yr: 1999 | Vol: 274 | Nbr: | Abs: | Pg: 15360-15366 |
| Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3 | ||||
| Periodical: Science | Index Medicus: | |||
| Authors: Li H, Kolluri S, Gu J, et al | ART | |||
| Yr: 2000 | Vol: 289 | Nbr: | Abs: | Pg: 1159-1164 |
| Orphan receptor COUP-TF is required for induction of RARbeta, growth inhibition and apoptosis by retinoic acid in cancer cells | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Lin B, Chen G, Ziao D, et al | ART | |||
| Yr: 2000 | Vol: 20 | Nbr: | Abs: | Pg: 957-970 |
| Unique anti-activator protein-1 activity of retinoic acid receptor beta1 | ||||
| Periodical: Cancer Research | Index Medicus: | |||
| Authors: Lin F, Ziao D, Kolluri S, Zhang X-K | ART | |||
| Yr: 2000 | Vol: 60 | Nbr: | Abs: | Pg: 3271-3280 |
| Regulation of RARbeta expression by RAR- and RXR-selective retinoids in human lung cancer cell lines: effect on growth inhibition and apoptosis induction | ||||
| Periodical: International Journal of Cancer | Index Medicus: | |||
| Authors: Li Y, Dawson MI, Agadir A, et al | ART | |||
| Yr: 1998 | Vol: 75 | Nbr: | Abs: | Pg: 88-95 |
| Differential effect of retinoic acid on growth regulation by phorbol ester in human cancer cell lines | ||||
| Periodical: Journal of Biological Chemistry | Index Medicus: | |||
| Authors: Agadir A, Chen GQ, Bost F, Li Y, Mercola D, Zhang X-K | ART | |||
| Yr: 1999 | Vol: 274 | Nbr: | Abs: | Pg: 29779-29785 |
| Ligand-binding domain of thyroid hormone receptors modulates DNA binding and determines their bifunctional roles | ||||
| Periodical: New Biologist | Index Medicus: | |||
| Authors: Zhang XK, Wills KN, Graupner Gerhart, et al. | ART | |||
| Yr: 1991 | Vol: 3 | Nbr: 2 | Abs: | Pg: 169-181 |
| Thyroid hormone receptors repress estrogen receptor activation of a TRE | ||||
| Periodical: Molecular Endocrinology | Index Medicus: | |||
| Authors: Graupner G, Zhang X, Tzukerman M, et al | ART | |||
| Yr: 1992 | Vol: 5 | Nbr: 3 | Abs: | Pg: 365-372 |
| Regulatory functions of a non-ligand-binding thyorid hormone receptor isoform | ||||
| Periodical: | Index Medicus: | |||
| Authors: Hermann T, Zhang X, Tzukerman M, et al | ART | |||
| Yr: 1992 | Vol: 2 | Nbr: 7 | Abs: | Pg: 565-574 |
| Coordinate expression of functionally distinct thyroid hormone receptor alpha isoforms during neonatal brain development | ||||
| Periodical: Molecular Endocrinology | Index Medicus: | |||
| Authors: Wills KN, Zhang XK, Pfahl M | ART | |||
| Yr: 1991 | Vol: 5 | Nbr: 8 | Abs: | Pg: 1109-1119 |
| Inhibition of estrogen receptor activity by the tumor promoter 12-O-Tetradeconylphorbol-13-Acetate: a molecular analysis | ||||
| Periodical: Molecular Endocrinology | Index Medicus: | |||
| Authors: Tzukerman M, Zhang XK, Pfahl M | ART | |||
| Yr: 1991 | Vol: 5 | Nbr: 12 | Abs: | Pg: 1983-1992 |
| Antagonsism between retinoic acid receptors and AP-1: implications for tumor promotion and inflammation | ||||
| Periodical: New Biologist | Index Medicus: | |||
| Authors: Yang-Yen HF, Zhang XK, Graupner G, et al | ART | |||
| Yr: 1991 | Vol: 3 | Nbr: 12 | Abs: | Pg: 1206-1219 |
| DNA binding and dimerization determinants for thyroid hormone receptor alpha and its interaction with a nuclear protein | ||||
| Periodical: Molecular Endocrinology | Index Medicus: | |||
| Authors: Zhang XK, Tran PB, Pfahl M | ART | |||
| Yr: 1991 | Vol: 5 | Nbr: 12 | Abs: | Pg: 1909-1920 |
| Novel pathway for thyroid hormone receptor action through interaction with jun and fos oncogene activities | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Zhang XK, Wills KN, Husmann M, Hermann T, Pfahl M | ART | |||
| Yr: 1991 | Vol: 11 | Nbr: 12 | Abs: | Pg: 6016-6025 |
| Retinoid X receptor is an auxiliary protein for thyorid hormone and retinoic acid receptor | ||||
| Periodical: Nature | Index Medicus: | |||
| Authors: Zhang XK, Hoffmann B, Tran PB, Graupner G, Pfahl M | ART | |||
| Yr: 1992 | Vol: 355 | Nbr: 6359 | Abs: | Pg: 441-446 |
| RARgamma2 expression is regulated through a retinoic acid response element embedded in SP1 sites | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Lehmann JM, Zhang XK, Pfahl M | ART | |||
| Yr: 1992 | Vol: 12 | Nbr: | Abs: | Pg: 2976-2985 |
| Heterodimeric receptor complexes determine T3 and retinoid signaling specificities | ||||
| Periodical: Molecular Endocrinology | Index Medicus: | |||
| Authors: Hermann T, Hoffmann B, Zhang XK, Tran P, Pfahl M | ART | |||
| Yr: 1992 | Vol: | Nbr: | Abs: | Pg: |
| 9-cis retinoic acid induces RXR homodimer formation: a mechanism defining a novel retinoid pathway | ||||
| Periodical: Nature | Index Medicus: | |||
| Authors: Zhang XK, Lehmann JM, Hoffmann B, et al | ART | |||
| Yr: 1992 | Vol: | Nbr: | Abs: | Pg: |
| Ligand-binding domain of thyroid hormone receptors modulates DNA binding and determines their bifunctional roles | ||||
| Periodical: New Biologist | Index Medicus: | |||
| Authors: Zhang XK, Wills KN, Graupner Gerhart, et al. | ART | |||
| Yr: 1991 | Vol: 3 | Nbr: 2 | Abs: | Pg: 169-181 |
| Thyroid hormone receptors repress estrogen receptor activation of a TRE | ||||
| Periodical: Molecular Endocrinology | Index Medicus: | |||
| Authors: Graupner G, Zhang X, Tzukerman M, et al | ART | |||
| Yr: 1992 | Vol: 5 | Nbr: 3 | Abs: | Pg: 365-372 |
| Regulatory functions of a non-ligand-binding thyorid hormone receptor isoform | ||||
| Periodical: | Index Medicus: | |||
| Authors: Hermann T, Zhang X, Tzukerman M, et al | ART | |||
| Yr: 1992 | Vol: 2 | Nbr: 7 | Abs: | Pg: 565-574 |
| Coordinate expression of functionally distinct thyroid hormone receptor alpha isoforms during neonatal brain development | ||||
| Periodical: Molecular Endocrinology | Index Medicus: | |||
| Authors: Wills KN, Zhang XK, Pfahl M | ART | |||
| Yr: 1991 | Vol: 5 | Nbr: 8 | Abs: | Pg: 1109-1119 |
| Inhibition of estrogen receptor activity by the tumor promoter 12-O-Tetradeconylphorbol-13-Acetate: a molecular analysis | ||||
| Periodical: Molecular Endocrinology | Index Medicus: | |||
| Authors: Tzukerman M, Zhang XK, Pfahl M | ART | |||
| Yr: 1991 | Vol: 5 | Nbr: 12 | Abs: | Pg: 1983-1992 |
| Antagonsism between retinoic acid receptors and AP-1: implications for tumor promotion and inflammation | ||||
| Periodical: New Biologist | Index Medicus: | |||
| Authors: Yang-Yen HF, Zhang XK, Graupner G, et al | ART | |||
| Yr: 1991 | Vol: 3 | Nbr: 12 | Abs: | Pg: 1206-1219 |
| DNA binding and dimerization determinants for thyroid hormone receptor alpha and its interaction with a nuclear protein | ||||
| Periodical: Molecular Endocrinology | Index Medicus: | |||
| Authors: Zhang XK, Tran PB, Pfahl M | ART | |||
| Yr: 1991 | Vol: 5 | Nbr: 12 | Abs: | Pg: 1909-1920 |
| Novel pathway for thyroid hormone receptor action through interaction with jun and fos oncogene activities | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Zhang XK, Wills KN, Husmann M, Hermann T, Pfahl M | ART | |||
| Yr: 1991 | Vol: 11 | Nbr: 12 | Abs: | Pg: 6016-6025 |
| Retinoid X receptor is an auxiliary protein for thyorid hormone and retinoic acid receptor | ||||
| Periodical: Nature | Index Medicus: | |||
| Authors: Zhang XK, Hoffmann B, Tran PB, Graupner G, Pfahl M | ART | |||
| Yr: 1992 | Vol: 355 | Nbr: 6359 | Abs: | Pg: 441-446 |
| RARgamma2 expression is regulated through a retinoic acid response element embedded in SP1 sites | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Lehmann JM, Zhang XK, Pfahl M | ART | |||
| Yr: 1992 | Vol: 12 | Nbr: | Abs: | Pg: 2976-2985 |
| Heterodimeric receptor complexes determine T3 and retinoid signaling specificities | ||||
| Periodical: Molecular Endocrinology | Index Medicus: | |||
| Authors: Hermann T, Hoffmann B, Zhang XK, Tran P, Pfahl M | ART | |||
| Yr: 1992 | Vol: | Nbr: | Abs: | Pg: |
| 9-cis retinoic acid induces RXR homodimer formation: a mechanism defining a novel retinoid pathway | ||||
| Periodical: Nature | Index Medicus: | |||
| Authors: Zhang XK, Lehmann JM, Hoffmann B, et al | ART | |||
| Yr: 1992 | Vol: | Nbr: | Abs: | Pg: |
| Mitogenic effect of orphan receptor TR3 and its regulation by MEKK1 in Lung Cancer Cells. | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Kolluri S, Cao X, Bruey-Sedano N, Lin B, Lin F, Han Y-H, Dawson MI, Zhang XK | ART | |||
| Yr: 2003 | Vol: 23 | Nbr: | Abs: | Pg: 8651-8667 |
| Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3 | ||||
| Periodical: Cell | Index Medicus: | |||
| Authors: Lin B, Kolluri S, Cao X, Li H, Han Y-H, Lin F, Reed JC, Zhang X-K | ART | |||
| Yr: 2004 | Vol: 116 | Nbr: | Abs: | Pg: 1-20 |
| Antagonist analogue of 6-[3'-(1-adamantyl)-4'-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN) family of apoptosis inducers that effectively blocks AHPN-induced apoptosis but not cell-cycle arrest. | ||||
| Periodical: Journal of Medicinal Chemistry | Index Medicus: | |||
| Authors: Dawson MI, Harris D, Liu G, Hobbs P, Lange C, Jong L, Bruey-Sedano N, James S | ART | |||
| Yr: 2004 | Vol: 47 | Nbr: | Abs: | Pg: 3518 - 3536 |
| Regulation of nur77 nuclear export by c-Jun N-terminal kinase and akt. | ||||
| Periodical: Oncogene | Index Medicus: | |||
| Authors: Han YH, Cao X, Lin B, Lin F, Kolluri SK, Reed JC, Dawson MI, Zhang XK | ART | |||
| Yr: 2006 | Vol: | Nbr: | Abs: | Pg: 1 - 13 |
| Mitogenic effect of orphan receptor TR3 and its regulation by MEKK1 in Lung Cancer Cells. | ||||
| Periodical: Molecular and Cellular Biology | Index Medicus: | |||
| Authors: Kolluri S, Cao X, Bruey-Sedano N, Lin B, Lin F, Han Y-H, Dawson MI, Zhang XK | ART | |||
| Yr: 2003 | Vol: 23 | Nbr: | Abs: | Pg: 8651-8667 |
| Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3 | ||||
| Periodical: Cell | Index Medicus: | |||
| Authors: Lin B, Kolluri S, Cao X, Li H, Han Y-H, Lin F, Reed JC, Zhang X-K | ART | |||
| Yr: 2004 | Vol: 116 | Nbr: | Abs: | Pg: 1-20 |
| Antagonist analogue of 6-[3'-(1-adamantyl)-4'-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN) family of apoptosis inducers that effectively blocks AHPN-induced apoptosis but not cell-cycle arrest. | ||||
| Periodical: Journal of Medicinal Chemistry | Index Medicus: | |||
| Authors: Dawson MI, Harris D, Liu G, Hobbs P, Lange C, Jong L, Bruey-Sedano N, James S | ART | |||
| Yr: 2004 | Vol: 47 | Nbr: | Abs: | Pg: 3518 - 3536 |
| Regulation of nur77 nuclear export by c-Jun N-terminal kinase and akt. | ||||
| Periodical: Oncogene | Index Medicus: | |||
| Authors: Han YH, Cao X, Lin B, Lin F, Kolluri SK, Reed JC, Dawson MI, Zhang XK | ART | |||
| Yr: 2006 | Vol: | Nbr: | Abs: | Pg: 1 - 13 |
| Determinants of Retinoid X Receptor transcriptional Antagonism J. Med Chem: 47: 4360-4372.2004 | ||||
| Periodical: | Index Medicus: | |||
| Authors: Cavasotto, C.N., Liu, G., James S.Y., Hobbs, P.D., Petterson, V. J.,Zhang,X-K | ART | |||
| Yr: | Vol: | Nbr: | Abs: | Pg: |
| The R-enantiomer of the Non-steroidal Anti-inflammatory Frug Etodolac Binds Retinoid X Receptor and Induces Tumor -selective Apoptosis. PNAS 102:2525-30.2005 | ||||
| Periodical: | Index Medicus: | |||
| Authors: Kolluri, S.K., Corr, M., James, S.Y., Berasconi, M., Lu, D., Liu, W., Zhang, X-K | ART | |||
| Yr: | Vol: | Nbr: | Abs: | Pg: |
| Determinants of Retinoid X Receptor Transcriptional Antagonism J Med Chem. 47: 4360-4372.2004 | ||||
| Periodical: | Index Medicus: | |||
| Authors: Cavasotto, C.N., Liu, G., James. S.Y., Hobbs, P.D., Peterson, V.J., Zhang, X-K., | ART | |||
| Yr: | Vol: | Nbr: | Abs: | Pg: |
| The R-enantiomer of the Non-steroidal Anti-inflammatory Drug Etodolax Binds Retinoid X Receptor and Induces Tumor -selective Appoptosis PNAS 102 2525-30 2005 | ||||
| Periodical: | Index Medicus: | |||
| Authors: Zhang X-k | ART | |||
| Yr: | Vol: | Nbr: | Abs: | Pg: |
| Hypericum sampsonni induces apoptosis and nuclear export of retinoid X receptor-alpha | ||||
| Periodical: Carcinogenesis | Index Medicus: | |||
| Authors: Zeng JZ, Sun DF, Wang L, Cao X, Qi JB, Yang T, Hu CQ, Liu W, Zhang XK | ART | |||
| Yr: 2006 | Vol: | Nbr: | Abs: | Pg: |
| A structure-based approach to retinoid X receptor-alpha inhibition | ||||
| Periodical: Journal of Biological Chemistry | Index Medicus: | |||
| Authors: Stebbins JL, Jung D, Leone M, Zhang XK, Pellecchia M | ART | |||
| Yr: 2006 | Vol: 281 | Nbr: | Abs: | Pg: 16643-16648 |
| Regulation of Nur77 nuclear export by c-Jun N-terminal kinase and Akt | ||||
| Periodical: Oncogene | Index Medicus: | |||
| Authors: Han YH, Cao X, Lin B, Lin F, Kolluri SK, Stebbins J, Reed JC, Dawson MI, Zhang XK | ART | |||
| Yr: 2006 | Vol: 25 | Nbr: | Abs: | Pg: 2974-2986 |
| Transcription factors that directly target mitochondria for cell death induction | ||||
| Periodical: Oncogene | Index Medicus: | |||
| Authors: Moll UM, Marchenko N, Zhang XK | ART | |||
| Yr: 2006 | Vol: 25 | Nbr: | Abs: | Pg: 4725-43 |
| Exploiting the TR3 interaction with Bcl-2 as a novel therapeutic strategy of cancer and leukemia therapy. | ||||
| Periodical: Blood | Index Medicus: | |||
| Authors: Zhai, DY, Sergienko, E, Kitada, S, Luciano, F, Satterswaitk AC, Zhang, XK, and Reed, JC | ART | |||
| Yr: 2006 | Vol: 108 | Nbr: 80A-80A | Abs: | Pg: 256 Part 1 |
| A novel peptide containing a nine amino acid sequence from Nur77 induces Bcl-2-dependent apoptosis in AML. | ||||
| Periodical: Blood | Index Medicus: | |||
| Authors: Andreeff, M, Konopleva, M, Watt, JC, Samudio, IJ, Satterthwait, AC, Kitada, S, Zhang, XK, | ART | |||
| Yr: 0 | Vol: 108 (11) | Nbr: 736A-736A | Abs: | Pg: 2607 Part 1 |
| Targeting Nur77 Translocation. | ||||
| Periodical: Expert Opinion on Therapeutic Targets | Index Medicus: | |||
| Authors: Zhang, XK | ART | |||
| Yr: 2007 | Vol: 11 | Nbr: | Abs: | Pg: 59-79 |
| An adamantyl-substituted retinoid-derived molec that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nucl recptoor: Effects of modifying its carboxylate grp on apoptosis, proliferation, & pro | ||||
| Periodical: Journal Medical Chemistry | Index Medicus: | |||
| Authors: Dawson, MI, Xia, ZB, Liu, G, Fontana, JA,Farhana, L, Patel, BB, Arumugarajah, S, Bhuiyan, | ART | |||
| Yr: 0 | Vol: 50 | Nbr: 11 | Abs: | Pg: 2622-2639 |
| Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs. | ||||
| Periodical: Proceedings of the National Academy of Sciences of the United States of America | Index Medicus: | |||
| Authors: Bisson,WH, Cheltsov,AV, Bruey-Sedano,N, Lin,B, Chen,J,Goldberger,N, May, LT, Christopoulos | ART | |||
| Yr: 2007 | Vol: 104 | Nbr: 29 | Abs: | Pg: 11927-11932 |
| Nur77 converts phenotype of Bcl-B, an anti-apoptotic protein expressed in plasma cells and myeloma. | ||||
| Periodical: Blood | Index Medicus: | |||
| Authors: Luciano,F,Krajewska,M,Ortiz-Rubio,P,Krajewski,S,Zhai,D,Faustin,B,Bruey,JM,Bailly-Maitre,B, | ART | |||
| Yr: 2007 | Vol: 109 | Nbr: 9 | Abs: | Pg: 3849-3855 |
| Nongenomic actions of retinoids:Role of Nur77 and RXR in the regulation of apoptosis and inflammation. | ||||
| Periodical: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry | Index Medicus: | |||
| Authors: Zeng, JZ, and Zhang, XK | ART | |||
| Yr: 2007 | Vol: 6 | Nbr: | Abs: | Pg: 315-331 |
| RXR agonists inhibits high glucose induced oxidative stress by repressing PKC activity in human endothelial cells. | ||||
| Periodical: Free Radical Biology and Medicine | Index Medicus: | |||
| Authors: Chai, D, Wang, B, hen,L, Pn, J, Zhang, XK and He, B | ART | |||
| Yr: 2008 | Vol: 44 | Nbr: | Abs: | Pg: 1334-1347 |
| A short Nur77-derived peptide converts Bcl-2 from a protector to a killer of cancer cells. | ||||
| Periodical: | Index Medicus: | |||
| Authors: Kolluri,S,Zhu,X,Zhou,X, Lin B, Chen,Y,Town,J,Cao,X,Lin,F,Zhai,D,Kitada,S,Luciano,F,Reed,JC | ART | |||
| Yr: | Vol: | Nbr: | Abs: | Pg: |
| Modulation of Nur77-mediated apoptotic pathway by acetylshikonin and analogs | ||||
| Periodical: | Index Medicus: | |||
| Authors: Liu,J,Zhou,W,Li,S,Sun,Z,Lin,B,Lang,Y,He,J,Cao,X,Yan,T,Wang,L,Lu,J,Han,Y,Cao,Y,Zhang,X,Zen | ART | |||
| Yr: | Vol: | Nbr: | Abs: | Pg: |
| Determinants of Retinoid X Receptor transcriptional Antagonism J. Med Chem: 47: 4360-4372.2004 | ||||
| Periodical: | Index Medicus: | |||
| Authors: Cavasotto, C.N., Liu, G., James S.Y., Hobbs, P.D., Petterson, V. J.,Zhang,X-K | ART | |||
| Yr: | Vol: | Nbr: | Abs: | Pg: |
| The R-enantiomer of the Non-steroidal Anti-inflammatory Frug Etodolac Binds Retinoid X Receptor and Induces Tumor -selective Apoptosis. PNAS 102:2525-30.2005 | ||||
| Periodical: | Index Medicus: | |||
| Authors: Kolluri, S.K., Corr, M., James, S.Y., Berasconi, M., Lu, D., Liu, W., Zhang, X-K | ART | |||
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| Determinants of Retinoid X Receptor Transcriptional Antagonism J Med Chem. 47: 4360-4372.2004 | ||||
| Periodical: | Index Medicus: | |||
| Authors: Cavasotto, C.N., Liu, G., James. S.Y., Hobbs, P.D., Peterson, V.J., Zhang, X-K., | ART | |||
| Yr: | Vol: | Nbr: | Abs: | Pg: |
| The R-enantiomer of the Non-steroidal Anti-inflammatory Drug Etodolax Binds Retinoid X Receptor and Induces Tumor -selective Appoptosis PNAS 102 2525-30 2005 | ||||
| Periodical: | Index Medicus: | |||
| Authors: Zhang X-k | ART | |||
| Yr: | Vol: | Nbr: | Abs: | Pg: |
| Hypericum sampsonni induces apoptosis and nuclear export of retinoid X receptor-alpha | ||||
| Periodical: Carcinogenesis | Index Medicus: | |||
| Authors: Zeng JZ, Sun DF, Wang L, Cao X, Qi JB, Yang T, Hu CQ, Liu W, Zhang XK | ART | |||
| Yr: 2006 | Vol: | Nbr: | Abs: | Pg: |
| A structure-based approach to retinoid X receptor-alpha inhibition | ||||
| Periodical: Journal of Biological Chemistry | Index Medicus: | |||
| Authors: Stebbins JL, Jung D, Leone M, Zhang XK, Pellecchia M | ART | |||
| Yr: 2006 | Vol: 281 | Nbr: | Abs: | Pg: 16643-16648 |
| Regulation of Nur77 nuclear export by c-Jun N-terminal kinase and Akt | ||||
| Periodical: Oncogene | Index Medicus: | |||
| Authors: Han YH, Cao X, Lin B, Lin F, Kolluri SK, Stebbins J, Reed JC, Dawson MI, Zhang XK | ART | |||
| Yr: 2006 | Vol: 25 | Nbr: | Abs: | Pg: 2974-2986 |
| Transcription factors that directly target mitochondria for cell death induction | ||||
| Periodical: Oncogene | Index Medicus: | |||
| Authors: Moll UM, Marchenko N, Zhang XK | ART | |||
| Yr: 2006 | Vol: 25 | Nbr: | Abs: | Pg: 4725-43 |
| Exploiting the TR3 interaction with Bcl-2 as a novel therapeutic strategy of cancer and leukemia therapy. | ||||
| Periodical: Blood | Index Medicus: | |||
| Authors: Zhai, DY, Sergienko, E, Kitada, S, Luciano, F, Satterswaitk AC, Zhang, XK, and Reed, JC | ART | |||
| Yr: 2006 | Vol: 108 | Nbr: 80A-80A | Abs: | Pg: 256 Part 1 |
| A novel peptide containing a nine amino acid sequence from Nur77 induces Bcl-2-dependent apoptosis in AML. | ||||
| Periodical: Blood | Index Medicus: | |||
| Authors: Andreeff, M, Konopleva, M, Watt, JC, Samudio, IJ, Satterthwait, AC, Kitada, S, Zhang, XK, | ART | |||
| Yr: 0 | Vol: 108 (11) | Nbr: 736A-736A | Abs: | Pg: 2607 Part 1 |
| Targeting Nur77 Translocation. | ||||
| Periodical: Expert Opinion on Therapeutic Targets | Index Medicus: | |||
| Authors: Zhang, XK | ART | |||
| Yr: 2007 | Vol: 11 | Nbr: | Abs: | Pg: 59-79 |
| An adamantyl-substituted retinoid-derived molec that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nucl recptoor: Effects of modifying its carboxylate grp on apoptosis, proliferation, & pro | ||||
| Periodical: Journal Medical Chemistry | Index Medicus: | |||
| Authors: Dawson, MI, Xia, ZB, Liu, G, Fontana, JA,Farhana, L, Patel, BB, Arumugarajah, S, Bhuiyan, | ART | |||
| Yr: 0 | Vol: 50 | Nbr: 11 | Abs: | Pg: 2622-2639 |
| Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs. | ||||
| Periodical: Proceedings of the National Academy of Sciences of the United States of America | Index Medicus: | |||
| Authors: Bisson,WH, Cheltsov,AV, Bruey-Sedano,N, Lin,B, Chen,J,Goldberger,N, May, LT, Christopoulos | ART | |||
| Yr: 2007 | Vol: 104 | Nbr: 29 | Abs: | Pg: 11927-11932 |
| Nur77 converts phenotype of Bcl-B, an anti-apoptotic protein expressed in plasma cells and myeloma. | ||||
| Periodical: Blood | Index Medicus: | |||
| Authors: Luciano,F,Krajewska,M,Ortiz-Rubio,P,Krajewski,S,Zhai,D,Faustin,B,Bruey,JM,Bailly-Maitre,B, | ART | |||
| Yr: 2007 | Vol: 109 | Nbr: 9 | Abs: | Pg: 3849-3855 |
| Nongenomic actions of retinoids:Role of Nur77 and RXR in the regulation of apoptosis and inflammation. | ||||
| Periodical: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry | Index Medicus: | |||
| Authors: Zeng, JZ, and Zhang, XK | ART | |||
| Yr: 2007 | Vol: 6 | Nbr: | Abs: | Pg: 315-331 |
| RXR agonists inhibits high glucose induced oxidative stress by repressing PKC activity in human endothelial cells. | ||||
| Periodical: Free Radical Biology and Medicine | Index Medicus: | |||
| Authors: Chai, D, Wang, B, hen,L, Pn, J, Zhang, XK and He, B | ART | |||
| Yr: 2008 | Vol: 44 | Nbr: | Abs: | Pg: 1334-1347 |
| A short Nur77-derived peptide converts Bcl-2 from a protector to a killer of cancer cells. | ||||
| Periodical: | Index Medicus: | |||
| Authors: Kolluri,S,Zhu,X,Zhou,X, Lin B, Chen,Y,Town,J,Cao,X,Lin,F,Zhai,D,Kitada,S,Luciano,F,Reed,JC | ART | |||
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| Modulation of Nur77-mediated apoptotic pathway by acetylshikonin and analogs | ||||
| Periodical: | Index Medicus: | |||
| Authors: Liu,J,Zhou,W,Li,S,Sun,Z,Lin,B,Lang,Y,He,J,Cao,X,Yan,T,Wang,L,Lu,J,Han,Y,Cao,Y,Zhang,X,Zen | ART | |||
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