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Ruth Gjerset, Ph.D.

Torrey Pines Institute for Molecular Studies # of Grants: 3

Grants

Targeted Delivery of p53 to Lung Carcinoma Cells 1995 (Cycle 4) $143,150
Cancer Inno Dev & Exp Awards (IDEAS)

p53 and p14ARF: Multiple pathways of lung cancer suppression 2002 (Cycle 11) $821,050
Cancer Research Project Awards

Novel Therapy Sensitization Strategy for Lung Cancer 2009 (Cycle 18) $450,000
Cancer Exploratory/Developmental Award
Publications

Use of wild-type p53 to achieve complete treatment sensitization of tumor cells expressing endogenous mutant p53
Periodical: Molecular Carcinogenesis Index Medicus:
Authors: Gjerset RA, Turla ST, Sobol SE, et al ART
Yr: 1995 Vol: 14 Nbr: 4 Abs: Pg: 175-185

The jun kinase/stress activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplain
Periodical: Journal of Biological Chemistry Index Medicus:
Authors: Potapova O, Haghighi A, Bost F, et al ART
Yr: 0 Vol: Nbr: Abs: Pg:

Sensitization of rat glioblastoma multiforme to cisplatin in vivo following restoration of wild-type p53 functions
Periodical: Journal of Neurosurgery Index Medicus:
Authors: Dorigo O, Turla ST, Lebedeva S, Gjerset RA ART
Yr: 1998 Vol: 88 Nbr: 3 Abs: Pg: 535-540

Enhanced tumor suppression by a p14ARF/p53 bicistronic adenovirus through increased p53 protein translation and stability.
Periodical: Cancer Research Index Medicus:
Authors: Huang Y, Tyler T, Saadatmandi N, Lee C, Borgstrom P, Gjerset R ART
Yr: 2003 Vol: 63 Nbr: Abs: Pg: 3646-3653

Role in the cellular stress response and applications to cancer.
Periodical: Cancer Therapy Index Medicus:
Authors: Huang Y, Gjerset RA ART
Yr: 2003 Vol: 1 Nbr: Abs: Pg: 343-351

DNA damage disrupts the p14 ARF/B23(NPM) interaction and tiggers a transient subnuclear redistribution of p14 ARF (submitted 2005)
Periodical: Cancer Research Index Medicus:
Authors: lee C, Smith BA, Gjerset RA. ART
Yr: 2005 Vol: 65 Nbr: Abs: Pg: 9834-9842

DNA damage, p14ARF, nucleophosmin (NPM/B23), and cancer.
Periodical: Journal Molecular Histol Index Medicus:
Authors: Gjerset R, ART
Yr: 2006 Vol: Nbr: Abs: Pg:

Regulation of p14ARF through subnuclear compartmentalization
Periodical: Cell Cycle Index Medicus:
Authors: Gjerset R, Bandyopadhyay K. ART
Yr: 2006 Vol: 5 Nbr: 7 Abs: Pg: 686-690

Spermidinyl-CoA-based HAT inhibitors block DNA repair and provide cancer-specific chemo- and radiosensitization
Periodical: Cell Cycle Index Medicus:
Authors: Bandyopadhyay K, Banères JL, Martin A, Blonski C, Parello J, Gjerset RA ART
Yr: 2009 Vol: 1 Nbr: 8 (17) Abs: Pg: 2779-88