Henry Lester, Ph.D.
|
California Institute of Technology
|
|
# of Grants: 9 |
Grants
|
| Heterologous Expression of Brain Nicotinic Acetylcholine Receptor |
1995 (Cycle 4) |
$598,774 |
| Nicotine Dependence |
Research Project Awards |
|
| Hyperactive nicotine receptors |
1997 (Cycle 6) |
$486,158 |
| Nicotine Dependence |
Research Project Awards |
|
| Heterologous Expression of Brain Nicotinic Receptors |
1992 (Cycle 1) |
$586,840 |
| Nicotine Dependence |
Research Project Awards |
|
| Hyperactive nicotine receptors |
2000 (Cycle 9) |
$1,138,225 |
| Nicotine Dependence |
Research Project Awards |
|
| Hyperactive nicotine receptors |
2003 (Cycle 12) |
$675,487 |
| Nicotine Dependence |
Research Project Awards |
|
| Nicotinic receptors in nicotine addiction |
2008 (Cycle 17) |
$634,743 |
| Nicotine Dependence |
Research Project Awards |
|
| Nicotine Receptor in Nicotine Dependence |
2011 (Cycle 20) |
$404,642 |
| Nicotine Dependence |
Exploratory/Developmental Award |
|
| Subcellular pharmacokinetics of nicotinic compounds |
2014 (Cycle 23) |
$314,942 |
| Disparities /Prevention/ Cessation/ Nicotine Dependence |
Exploratory/Developmental Award |
|
| Understanding Nicotine and Smoking Cessation Drugs: Release |
2018 (Cycle 27) |
$660,000 |
| Neuroscience of Nicotine Addiction and Treatment |
High Impact Pilot Award |
Publications
| Regions of beta-2 and beta-4 responsible for differences between the equilibrium dose-response relationships of the alpha3beta2 and alpha3beta4 neuronal nicotinic receptors |
| Periodical: Journal of General Physiology |
Index Medicus: |
| Authors: Cohen BN, Figl A, Quick M, Labarca C, Davidson N, Lester HA |
ART |
| Yr: 0 |
Vol: |
Nbr: |
Abs: |
Pg: |
| Nicotinic receptor binding site probed with unnatural amino-acid incorporation in intact cells |
| Periodical: Science |
Index Medicus: |
| Authors: Nowak MW, Kearney PC, Sampson JR, et al |
ART |
| Yr: 1995 |
Vol: 268 |
Nbr: 5209 |
Abs: |
Pg: 439-442 |
| Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic recptors |
| Periodical: Nature |
Index Medicus: |
| Authors: Labarca C, Nowak M, Zhang H, Tang L, Deshpande P, Lester HA |
ART |
| Yr: 1995 |
Vol: 376 |
Nbr: 6540 |
Abs: |
Pg: 514-516 |
| Voltage-jump relaxation kinetics for wild type and chimeric beta subunits of neuronal nicotinic receptors |
| Periodical: Journal of General Physiology |
Index Medicus: |
| Authors: Figl A, Labarca C, Davidson N, Lester HA, Cohen BN |
ART |
| Yr: 1996 |
Vol: 107 |
Nbr: 3 |
Abs: |
Pg: 369-379 |
| Regions of beta2 and beta4 responsible for differences between the equilibrium dose-response relatioships of the alpha3beta2 and alpha3beta4 neuronal nicotinic receptors |
| Periodical: Journal of General Physiology |
Index Medicus: |
| Authors: Cohen BN, Figl A, Quick MW, Labarca C, Davidson N, Lester HA |
ART |
| Yr: 0 |
Vol: Article in |
Nbr: Press |
Abs: |
Pg: |
| Site-specific, photochemical proteolysis applied to ion channels In Vivo |
| Periodical: Proceedings of the National Academy of Sciences of the United States of America |
Index Medicus: |
| Authors: England P, Lester HA, Davidson N, Dougherty DA |
ART |
| Yr: 1997 |
Vol: 94 |
Nbr: |
Abs: |
Pg: 11025-11030 |
| Expression and circular dichroism studies of the extracellular domain of the alpha subunit of the nicotinic acetylcholine receptor |
| Periodical: Journal of Biological Chemistry |
Index Medicus: |
| Authors: West AP, Bjorkman PJ, Dougherty DA, Lester HA |
ART |
| Yr: 1997 |
Vol: 272 |
Nbr: |
Abs: |
Pg: 25468-25473 |
| From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor |
| Periodical: Proceedings of the National Academy of Sciences of the United States of America |
Index Medicus: |
| Authors: Zhong W, Gallivan JP, Zhang Y, Li L, Lester HA, Dougherty DA |
ART |
| Yr: 1998 |
Vol: |
Nbr: |
Abs: |
Pg: |
| Regions of beta-2 and beta-4 responsible for differences between the equilibrium dose-response relationships of the alpha3beta2 and alpha3beta4 neuronal nicotinic receptors |
| Periodical: Journal of General Physiology |
Index Medicus: |
| Authors: Cohen BN, Figl A, Quick M, Labarca C, Davidson N, Lester HA |
ART |
| Yr: 0 |
Vol: |
Nbr: |
Abs: |
Pg: |
| Nicotinic receptor binding site probed with unnatural amino-acid incorporation in intact cells |
| Periodical: Science |
Index Medicus: |
| Authors: Nowak MW, Kearney PC, Sampson JR, et al |
ART |
| Yr: 1995 |
Vol: 268 |
Nbr: 5209 |
Abs: |
Pg: 439-442 |
| Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic recptors |
| Periodical: Nature |
Index Medicus: |
| Authors: Labarca C, Nowak M, Zhang H, Tang L, Deshpande P, Lester HA |
ART |
| Yr: 1995 |
Vol: 376 |
Nbr: 6540 |
Abs: |
Pg: 514-516 |
| Voltage-jump relaxation kinetics for wild type and chimeric beta subunits of neuronal nicotinic receptors |
| Periodical: Journal of General Physiology |
Index Medicus: |
| Authors: Figl A, Labarca C, Davidson N, Lester HA, Cohen BN |
ART |
| Yr: 1996 |
Vol: 107 |
Nbr: 3 |
Abs: |
Pg: 369-379 |
| Regions of beta2 and beta4 responsible for differences between the equilibrium dose-response relatioships of the alpha3beta2 and alpha3beta4 neuronal nicotinic receptors |
| Periodical: Journal of General Physiology |
Index Medicus: |
| Authors: Cohen BN, Figl A, Quick MW, Labarca C, Davidson N, Lester HA |
ART |
| Yr: 0 |
Vol: Article in |
Nbr: Press |
Abs: |
Pg: |
| Site-specific, photochemical proteolysis applied to ion channels In Vivo |
| Periodical: Proceedings of the National Academy of Sciences of the United States of America |
Index Medicus: |
| Authors: England P, Lester HA, Davidson N, Dougherty DA |
ART |
| Yr: 1997 |
Vol: 94 |
Nbr: |
Abs: |
Pg: 11025-11030 |
| Expression and circular dichroism studies of the extracellular domain of the alpha subunit of the nicotinic acetylcholine receptor |
| Periodical: Journal of Biological Chemistry |
Index Medicus: |
| Authors: West AP, Bjorkman PJ, Dougherty DA, Lester HA |
ART |
| Yr: 1997 |
Vol: 272 |
Nbr: |
Abs: |
Pg: 25468-25473 |
| From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor |
| Periodical: Proceedings of the National Academy of Sciences of the United States of America |
Index Medicus: |
| Authors: Zhong W, Gallivan JP, Zhang Y, Li L, Lester HA, Dougherty DA |
ART |
| Yr: 1998 |
Vol: |
Nbr: |
Abs: |
Pg: |
| From ab initio quantum mechanics to molecular neurobiology: A cation- binding site in the nicotinic receptor |
| Periodical: Proceedings of the National Academy of Sciences of the United States of America |
Index Medicus: |
| Authors: Zhong W, Gallivan JP, Zhang Y, Li L, Lester HA, Dougherty DA |
ART |
| Yr: 1998 |
Vol: 95 |
Nbr: |
Abs: |
Pg: 12088-12095 |
| Point mutant mice with hypersensitive a4 nicotinic receptors show dopaminergic deficits and increased anxiety |
| Periodical: Proceedings of the National Academy of Sciences of the United States of America |
Index Medicus: |
| Authors: Labarca C, Schwarz J, Deshpande P, et al |
ART |
| Yr: 2001 |
Vol: 98 |
Nbr: |
Abs: |
Pg: 2786-2791 |
| From ab initio quantum mechanics to molecular neurobiology: A cation- binding site in the nicotinic receptor |
| Periodical: Proceedings of the National Academy of Sciences of the United States of America |
Index Medicus: |
| Authors: Zhong W, Gallivan JP, Zhang Y, Li L, Lester HA, Dougherty DA |
ART |
| Yr: 1998 |
Vol: 95 |
Nbr: |
Abs: |
Pg: 12088-12095 |
| Point mutant mice with hypersensitive a4 nicotinic receptors show dopaminergic deficits and increased anxiety |
| Periodical: Proceedings of the National Academy of Sciences of the United States of America |
Index Medicus: |
| Authors: Labarca C, Schwarz J, Deshpande P, et al |
ART |
| Yr: 2001 |
Vol: 98 |
Nbr: |
Abs: |
Pg: 2786-2791 |
| TRIS+ NA+ permeability ratios of nicotinic acetylcholine receptors are reduced by mutations near the intracellular end of the M2 region |
| Periodical: Journal of General Physiology |
Index Medicus: |
| Authors: Cohen BN, Labarca C, Czyzyk L, Davidson N, Lester HA |
ART |
| Yr: 1992 |
Vol: 99 |
Nbr: |
Abs: |
Pg: 545-572 |
| Pharmacological and kinetic properties of alpha4beta2 neuronal nicotinic acetylcholine receports expressed in Xenopus oocytes |
| Periodical: |
Index Medicus: |
| Authors: Charnet P, Labarca C, Cohen BC, Davidson N, Lester HA, Pilar G |
ART |
| Yr: 1992 |
Vol: 450 |
Nbr: |
Abs: |
Pg: 375-394 |
| Structure of the gamma-less nicotinic acetylcholine receptor: learning from omission |
| Periodical: Molecular Pharmacology |
Index Medicus: |
| Authors: Charnet P, Labarca C, Lester HA |
ART |
| Yr: 1992 |
Vol: 41 |
Nbr: 4 |
Abs: |
Pg: 708-717 |
| Mutations in M2 alter the selectivity of the mouse nicotinic acetylcholine receptor for organic and for alkali metal cations |
| Periodical: Journal of General Physiology |
Index Medicus: |
| Authors: Cohen BN, Labarca C, Davidson N, Lester HA |
ART |
| Yr: 1992 |
Vol: 100 |
Nbr: 3 |
Abs: |
Pg: 373-400 |
| Regions of beta4.beta2 subunit chimeras that contribute to the agonist selectivity of neuronal nicotinic receptors |
| Periodical: FEBS Journal |
Index Medicus: |
| Authors: Figl A, Cohen BN, Quick MW, Davidson N, Lester HA |
ART |
| Yr: 1992 |
Vol: 308 |
Nbr: 3 |
Abs: |
Pg: 245-248 |
| The permeation pathway of neurotransmitter-gated ion channels |
| Periodical: Annual Review of Biophysics and Biomolecular Structure |
Index Medicus: |
| Authors: Lester HA |
ART |
| Yr: 1992 |
Vol: 21 |
Nbr: |
Abs: |
Pg: 267-292 |
| TRIS+ NA+ permeability ratios of nicotinic acetylcholine receptors are reduced by mutations near the intracellular end of the M2 region |
| Periodical: Journal of General Physiology |
Index Medicus: |
| Authors: Cohen BN, Labarca C, Czyzyk L, Davidson N, Lester HA |
ART |
| Yr: 1992 |
Vol: 99 |
Nbr: |
Abs: |
Pg: 545-572 |
| Pharmacological and kinetic properties of alpha4beta2 neuronal nicotinic acetylcholine receports expressed in Xenopus oocytes |
| Periodical: |
Index Medicus: |
| Authors: Charnet P, Labarca C, Cohen BC, Davidson N, Lester HA, Pilar G |
ART |
| Yr: 1992 |
Vol: 450 |
Nbr: |
Abs: |
Pg: 375-394 |
| Structure of the gamma-less nicotinic acetylcholine receptor: learning from omission |
| Periodical: Molecular Pharmacology |
Index Medicus: |
| Authors: Charnet P, Labarca C, Lester HA |
ART |
| Yr: 1992 |
Vol: 41 |
Nbr: 4 |
Abs: |
Pg: 708-717 |
| Mutations in M2 alter the selectivity of the mouse nicotinic acetylcholine receptor for organic and for alkali metal cations |
| Periodical: Journal of General Physiology |
Index Medicus: |
| Authors: Cohen BN, Labarca C, Davidson N, Lester HA |
ART |
| Yr: 1992 |
Vol: 100 |
Nbr: 3 |
Abs: |
Pg: 373-400 |
| Regions of beta4.beta2 subunit chimeras that contribute to the agonist selectivity of neuronal nicotinic receptors |
| Periodical: FEBS Journal |
Index Medicus: |
| Authors: Figl A, Cohen BN, Quick MW, Davidson N, Lester HA |
ART |
| Yr: 1992 |
Vol: 308 |
Nbr: 3 |
Abs: |
Pg: 245-248 |
| The permeation pathway of neurotransmitter-gated ion channels |
| Periodical: Annual Review of Biophysics and Biomolecular Structure |
Index Medicus: |
| Authors: Lester HA |
ART |
| Yr: 1992 |
Vol: 21 |
Nbr: |
Abs: |
Pg: 267-292 |
| Point mutant mice with hypersensitive alpha4 nicotinic receptors show dopaminergic deficits and increased anxiety |
| Periodical: Proceedings of the National Academy of Sciences of the United States of America |
Index Medicus: |
| Authors: Labarca C, Schwarz J, Deshpande P, et al |
ART |
| Yr: 98 |
Vol: |
Nbr: |
Abs: |
Pg: 2786-2791 |
| Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive alpha 4 nivotinic receptors. |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Fonck C, Nashmi R, Deshpande P, Damaj M, Riedel A, Schwarz J, Collins A, et.al |
ART |
| Yr: 2003 |
Vol: 23 |
Nbr: 7 |
Abs: |
Pg: 2582-2590 |
| Alpha4Beta2* nicotinic acetylcholine receptors modulate the effects of ethanol and nicotine on the acoustic startle response targets for both nicotine and ethanol. |
| Periodical: Alcoholism: Clinical and Experimental Research |
Index Medicus: |
| Authors: Owens JC, Balogh SA, McClure-Begley TD, Butt CM, Mabarca C, Lester HA, et.al |
ART |
| Yr: 2003 |
Vol: 27 |
Nbr: |
Abs: |
Pg: 1867-75 |
| Assembly of alpha4beta2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: Effects of localization, trafficking, and nicotine-induced upregulation in clonal mammalian cells and in cultured midbrain neurons. |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Nashmi R, Dickinson ME, McKinney S, Jareb M, Labarca C, Fraser SE, Lester HA |
ART |
| Yr: 2003 |
Vol: 23 |
Nbr: |
Abs: |
Pg: 11554-11567 |
| Point mutant mice with hypersensitive alpha4 nicotinic receptors show dopaminergic deficits and increased anxiety |
| Periodical: Proceedings of the National Academy of Sciences of the United States of America |
Index Medicus: |
| Authors: Labarca C, Schwarz J, Deshpande P, et al |
ART |
| Yr: 98 |
Vol: |
Nbr: |
Abs: |
Pg: 2786-2791 |
| Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive alpha 4 nivotinic receptors. |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Fonck C, Nashmi R, Deshpande P, Damaj M, Riedel A, Schwarz J, Collins A, et.al |
ART |
| Yr: 2003 |
Vol: 23 |
Nbr: 7 |
Abs: |
Pg: 2582-2590 |
| Alpha4Beta2* nicotinic acetylcholine receptors modulate the effects of ethanol and nicotine on the acoustic startle response targets for both nicotine and ethanol. |
| Periodical: Alcoholism: Clinical and Experimental Research |
Index Medicus: |
| Authors: Owens JC, Balogh SA, McClure-Begley TD, Butt CM, Mabarca C, Lester HA, et.al |
ART |
| Yr: 2003 |
Vol: 27 |
Nbr: |
Abs: |
Pg: 1867-75 |
| Assembly of alpha4beta2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: Effects of localization, trafficking, and nicotine-induced upregulation in clonal mammalian cells and in cultured midbrain neurons. |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Nashmi R, Dickinson ME, McKinney S, Jareb M, Labarca C, Fraser SE, Lester HA |
ART |
| Yr: 2003 |
Vol: 23 |
Nbr: |
Abs: |
Pg: 11554-11567 |
| Assembly of alpha4beta2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: Effects of localization, trafficking and nicotine-induced upregulation in clonal mammalian cells and in cultured midbrain neurons. |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Lester HA, Nashmi R, Dickinson ME, McKinney S, Jareb M, Labarca C, Fraser SE |
ART |
| Yr: 2003 |
Vol: 23 |
Nbr: |
Abs: |
Pg: 11554-11567 |
| An angstrom scale interaction between plasma membrane ATP-gated P2X2 and alpha4beta2 nicotinic channels measured with FRET and TIRF microscopy. |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Khakh BS, Fisher JA, Nashmi R, Bowser DN, Lester HA |
ART |
| Yr: 2005 |
Vol: 25 |
Nbr: |
Abs: |
Pg: 6911 - 6920 |
| Nicotine action on alpha4* receptors: sufficiennt for reward, tolerance and sensitization. |
| Periodical: Science |
Index Medicus: |
| Authors: Tapper A, McKinney S, Nashmi R, Schwarz J, Lester H, et al. |
ART |
| Yr: 2004 |
Vol: 306 |
Nbr: |
Abs: |
Pg: 1029 - 1032 |
| Nicotine action on a4 receptors: sufficient for reward, tolerance and sensitization science |
| Periodical: Science |
Index Medicus: |
| Authors: Tapper A, McKinney S, Nashmi R, Schwarz J, Deshapande P, Labarca C, Whiteaker P, Collins |
ART |
| Yr: 2004 |
Vol: |
Nbr: 306 |
Abs: |
Pg: 1029-1032 |
| Novel seizure phenotyphe and sleep disruptions in Knock-in mice with hypersensitive a4 nicotinic receptors |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Fonck C, Cohen BN, Nashmi R, Whiteaker P, Wagenaar D, Rodrigues-Pinguet N, Deshpande P, |
ART |
| Yr: 2005 |
Vol: |
Nbr: 25:49 |
Abs: |
Pg: 11396-11411 |
| An angstrom scale interaction between plasma membrane ATP-gated P2X2 and a4B2 nicotine channels measured with FRET and TIRF microscopy |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Khakh BS, Fisher JA, Nashmi R, Bowser DN and Lester HA |
ART |
| Yr: 2005 |
Vol: 25 |
Nbr: |
Abs: |
Pg: 6911-6920 |
| The prototoxin lynx 1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival |
| Periodical: Neuron |
Index Medicus: |
| Authors: Miwa, J., Stevens T., King S, Caldarone B., Ibanez-Tallon, I., Xiao, C., Fitzsimonds, R. |
ART |
| Yr: 2006 |
Vol: |
Nbr: 51 |
Abs: |
Pg: 1-14 |
| Enhanced expression of hypersensitive a4 nAChR in adult mice increases the loss of midbrain dopaminergic neurons |
| Periodical: FASEB Journal |
Index Medicus: |
| Authors: Schwarz, J., Schwarz S., Dorigo, O., Stutzer, A., Wegner, F., Labarca, C., Deshpande, P., |
ART |
| Yr: 2006 |
Vol: |
Nbr: 20 |
Abs: |
Pg: 935-946 |
| Assembly of alpha4beta2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: Effects of localization, trafficking and nicotine-induced upregulation in clonal mammalian cells and in cultured midbrain neurons. |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Lester HA, Nashmi R, Dickinson ME, McKinney S, Jareb M, Labarca C, Fraser SE |
ART |
| Yr: 2003 |
Vol: 23 |
Nbr: |
Abs: |
Pg: 11554-11567 |
| An angstrom scale interaction between plasma membrane ATP-gated P2X2 and alpha4beta2 nicotinic channels measured with FRET and TIRF microscopy. |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Khakh BS, Fisher JA, Nashmi R, Bowser DN, Lester HA |
ART |
| Yr: 2005 |
Vol: 25 |
Nbr: |
Abs: |
Pg: 6911 - 6920 |
| Nicotine action on alpha4* receptors: sufficiennt for reward, tolerance and sensitization. |
| Periodical: Science |
Index Medicus: |
| Authors: Tapper A, McKinney S, Nashmi R, Schwarz J, Lester H, et al. |
ART |
| Yr: 2004 |
Vol: 306 |
Nbr: |
Abs: |
Pg: 1029 - 1032 |
| Nicotine action on a4 receptors: sufficient for reward, tolerance and sensitization science |
| Periodical: Science |
Index Medicus: |
| Authors: Tapper A, McKinney S, Nashmi R, Schwarz J, Deshapande P, Labarca C, Whiteaker P, Collins |
ART |
| Yr: 2004 |
Vol: |
Nbr: 306 |
Abs: |
Pg: 1029-1032 |
| Novel seizure phenotyphe and sleep disruptions in Knock-in mice with hypersensitive a4 nicotinic receptors |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Fonck C, Cohen BN, Nashmi R, Whiteaker P, Wagenaar D, Rodrigues-Pinguet N, Deshpande P, |
ART |
| Yr: 2005 |
Vol: |
Nbr: 25:49 |
Abs: |
Pg: 11396-11411 |
| An angstrom scale interaction between plasma membrane ATP-gated P2X2 and a4B2 nicotine channels measured with FRET and TIRF microscopy |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Khakh BS, Fisher JA, Nashmi R, Bowser DN and Lester HA |
ART |
| Yr: 2005 |
Vol: 25 |
Nbr: |
Abs: |
Pg: 6911-6920 |
| The prototoxin lynx 1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival |
| Periodical: Neuron |
Index Medicus: |
| Authors: Miwa, J., Stevens T., King S, Caldarone B., Ibanez-Tallon, I., Xiao, C., Fitzsimonds, R. |
ART |
| Yr: 2006 |
Vol: |
Nbr: 51 |
Abs: |
Pg: 1-14 |
| Enhanced expression of hypersensitive a4 nAChR in adult mice increases the loss of midbrain dopaminergic neurons |
| Periodical: FASEB Journal |
Index Medicus: |
| Authors: Schwarz, J., Schwarz S., Dorigo, O., Stutzer, A., Wegner, F., Labarca, C., Deshpande, P., |
ART |
| Yr: 2006 |
Vol: |
Nbr: 20 |
Abs: |
Pg: 935-946 |
| In Vivo Activation of Midbrain Dopamine Neurons via Sensitized, High-Affinity a6* Nicotinic Acetycholine Receptors. |
| Periodical: Neuron |
Index Medicus: |
| Authors: Drenan, RM, Grady, SR. Whiteaker, P, McClure-Begley, T, McKinney, SJ, Miwa, JM, Bupp, S, |
ART |
| Yr: 2008 |
Vol: 60 |
Nbr: 1 |
Abs: |
Pg: 123-36 |
| Chronic nicotine selectively enhances a4B2 nicotinic acetycholine receptors in the nigrostriatal dopamine pathway |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Xiao, C, Nashmi, R, McKinney, S, Cai, H, McIntosh, JM, Lester, HA |
ART |
| Yr: 2009 |
Vol: |
Nbr: |
Abs: |
Pg: |
| In Vivo Activation of Midbrain Dopamine Neurons via Sensitized, High-Affinity a6* Nicotinic Acetycholine Receptors. |
| Periodical: Neuron |
Index Medicus: |
| Authors: Drenan, RM, Grady, SR. Whiteaker, P, McClure-Begley, T, McKinney, SJ, Miwa, JM, Bupp, S, |
ART |
| Yr: 2008 |
Vol: 60 |
Nbr: 1 |
Abs: |
Pg: 123-36 |
| Chronic nicotine selectively enhances a4B2 nicotinic acetycholine receptors in the nigrostriatal dopamine pathway |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Xiao, C, Nashmi, R, McKinney, S, Cai, H, McIntosh, JM, Lester, HA |
ART |
| Yr: 2009 |
Vol: |
Nbr: |
Abs: |
Pg: |
| Nicotine upregulates a4B2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning |
| Periodical: Journal of General Physiology |
Index Medicus: |
| Authors: Srinivasan R, Pantoja R, Moss FJ, Mackey EDW, Son C, Miwa J, and Lester HA |
ART |
| Yr: 2011 |
Vol: |
Nbr: 137 |
Abs: |
Pg: 59-79 |
| Characterizing functional a6B2 nicotinic acetylcholine receptors in vitro: mutant B2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells |
| Periodical: Biochemical Pharmacology |
Index Medicus: |
| Authors: Xiao C, Srinivasan R, Drenan RM, Mackey ED, Mcintosh JM, and Lester HA |
ART |
| Yr: 2011 |
Vol: |
Nbr: 82 |
Abs: |
Pg: 852-61 |
| Insights into the Neurobiology of the Nicotinic Cholinergic System and Nicotine Addiction from Mice Expressing Nicotinic Receptors Harboring Gain-of-Function Mutations. |
| Periodical: Pharmacological Reviews |
Index Medicus: |
| Authors: Drenan RM, and Lester HA |
ART |
| Yr: 2012 |
Vol: |
Nbr: |
Abs: |
Pg: PMID 22885704 |
| Psychiatric Drugs Bind to Classical Targets Within Early Exocytotic_x000D_
Pathways: Therapeutic Effects |
| Periodical: Biological Psychiatry |
Index Medicus: |
| Authors: Lester HA, Miwa JM, and Srinivasan R |
ART |
| Yr: 2012 |
Vol: |
Nbr: |
Abs: |
Pg: PMID 22771239 |
| a6* Nicotinic Acetylcholine Receptor Expression and Function in a_x000D_
Visual Salience Circuit |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Mackey ED, Engle SE, Kim MR, O'Neill HC, Wageman CR, Patzlaff NE, Wang Y, Grady SR, Mcinto |
ART |
| Yr: 2012 |
Vol: |
Nbr: 32 |
Abs: |
Pg: 10226-37 |
| Live-Cell Imaging of Single Receptor Composition Using Zero-Mode Waveguide Nanostructures |
| Periodical: Nano Letters |
Index Medicus: |
| Authors: Richards CI, Luong K, Srinivasan R, Turner SW, Dougherty DA, Korlach J, and Lester HA |
ART |
| Yr: 2012 |
Vol: |
Nbr: 12 |
Abs: |
Pg: 11474-80 |
| Pharmacological chaperoning of nicotinic acetylcholine receptors reduces the ER stress response |
| Periodical: Molecular Pharmacology |
Index Medicus: |
| Authors: Srinivasan R, Richards CI, Xiao C, Rhee D, Pantoja R, Dougherty DA, Miwa JM, and Lester HA |
ART |
| Yr: 2012 |
Vol: |
Nbr: 81 |
Abs: |
Pg: 759-69 |
| Transcriptional regulation by nicotine in dopaminergic neurons |
| Periodical: Biochemical Pharmacology |
Index Medicus: |
| Authors: Hanley BM, Williams BA, Srinivasan R, Cohen BN, Xiao C, Mackey ED, Wold BJ and Lester HA |
ART |
| Yr: 2013 |
Vol: 86 |
Nbr: |
Abs: |
Pg: 1074-83 |
| Nicotine upregulates a4B2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning |
| Periodical: Journal of General Physiology |
Index Medicus: |
| Authors: Srinivasan R, Pantoja R, Moss FJ, Mackey EDW, Son C, Miwa J, and Lester HA |
ART |
| Yr: 2011 |
Vol: |
Nbr: 137 |
Abs: |
Pg: 59-79 |
| Characterizing functional a6B2 nicotinic acetylcholine receptors in vitro: mutant B2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells |
| Periodical: Biochemical Pharmacology |
Index Medicus: |
| Authors: Xiao C, Srinivasan R, Drenan RM, Mackey ED, Mcintosh JM, and Lester HA |
ART |
| Yr: 2011 |
Vol: |
Nbr: 82 |
Abs: |
Pg: 852-61 |
| Insights into the Neurobiology of the Nicotinic Cholinergic System and Nicotine Addiction from Mice Expressing Nicotinic Receptors Harboring Gain-of-Function Mutations. |
| Periodical: Pharmacological Reviews |
Index Medicus: |
| Authors: Drenan RM, and Lester HA |
ART |
| Yr: 2012 |
Vol: |
Nbr: |
Abs: |
Pg: PMID 22885704 |
| Psychiatric Drugs Bind to Classical Targets Within Early Exocytotic_x000D_
Pathways: Therapeutic Effects |
| Periodical: Biological Psychiatry |
Index Medicus: |
| Authors: Lester HA, Miwa JM, and Srinivasan R |
ART |
| Yr: 2012 |
Vol: |
Nbr: |
Abs: |
Pg: PMID 22771239 |
| a6* Nicotinic Acetylcholine Receptor Expression and Function in a_x000D_
Visual Salience Circuit |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Mackey ED, Engle SE, Kim MR, O'Neill HC, Wageman CR, Patzlaff NE, Wang Y, Grady SR, Mcinto |
ART |
| Yr: 2012 |
Vol: |
Nbr: 32 |
Abs: |
Pg: 10226-37 |
| Live-Cell Imaging of Single Receptor Composition Using Zero-Mode Waveguide Nanostructures |
| Periodical: Nano Letters |
Index Medicus: |
| Authors: Richards CI, Luong K, Srinivasan R, Turner SW, Dougherty DA, Korlach J, and Lester HA |
ART |
| Yr: 2012 |
Vol: |
Nbr: 12 |
Abs: |
Pg: 11474-80 |
| Pharmacological chaperoning of nicotinic acetylcholine receptors reduces the ER stress response |
| Periodical: Molecular Pharmacology |
Index Medicus: |
| Authors: Srinivasan R, Richards CI, Xiao C, Rhee D, Pantoja R, Dougherty DA, Miwa JM, and Lester HA |
ART |
| Yr: 2012 |
Vol: |
Nbr: 81 |
Abs: |
Pg: 759-69 |
| Transcriptional regulation by nicotine in dopaminergic neurons |
| Periodical: Biochemical Pharmacology |
Index Medicus: |
| Authors: Hanley BM, Williams BA, Srinivasan R, Cohen BN, Xiao C, Mackey ED, Wold BJ and Lester HA |
ART |
| Yr: 2013 |
Vol: 86 |
Nbr: |
Abs: |
Pg: 1074-83 |
| Menthol alone upregulates midbrain nAChRs, alters nAChR subtype stoichiometry, alters dopamine neuron firing frequency, and prevents nicotine reward |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Henderson B, Wall T, Henley BM, Kim C, Nichols W, Moaddel R, Xiao C, Lester H |
ART |
| Yr: 2016 |
Vol: |
Nbr: 36 |
Abs: |
Pg: 2957-2974 |
| Menthol alone upregulates midbrain nAChRs, alters nAChR subtype stoichiometry, alters dopamine neuron firing frequency, and prevents nicotine reward |
| Periodical: Journal of Neuroscience |
Index Medicus: |
| Authors: Henderson B, Wall T, Henley BM, Kim C, Nichols W, Moaddel R, Xiao C, Lester H |
ART |
| Yr: 2016 |
Vol: |
Nbr: 36 |
Abs: |
Pg: 2957-2974 |
