High Impact Pilot Award
2019 (Cycle 30)
| Nicotinic Receptor Modulators in Nicotine Dependence | 2019 (Cycle 30) | $495,000 |
| University of California, Irvine | Neuroscience of Nicotine Addiction and Treatment | |
| The Role of p53-Ninj2 loop in Tumor Progression and Metastasis | 2019 (Cycle 30) | $492,239 |
| University of California, Davis | Cancer | |
| Analysis of tobacco toxin-genetic interactions through study of the dioxin-AHR pathway | 2019 (Cycle 30) | $589,712 |
| Stanford University | Cardiovascular and Cerebrovascular Disease | |
| Technology-Assisted Motivational Interviewing and Referral Coach: The TAMI Coach | 2019 (Cycle 30) | $499,418 |
| University of California, San Francisco | Tobacco-Use Prevention and Cessation | |
| The Use of Virtual Reality to Induce and Assess Nicotine Craving | 2019 (Cycle 30) | $335,352 |
| University of California, San Diego | Tobacco-Use Prevention and Cessation | |
| Impact of cigarette smoking on dental pulp mesenchymal stem cells mediated tissue regeneration | 2019 (Cycle 30) | $500,849 |
| University of the Pacific | Oral Disease and Dental Health | |
| A validated second hand smoking exposure model for Electronic Nicotine Delivery Systems (ENDS) | 2019 (Cycle 30) | $479,770 |
| University of California, Irvine | Environmental Exposure/Toxicology | |
| Effects of tobacco and e-cigarettes on heart repair and regeneration | 2019 (Cycle 30) | $678,000 |
| Childrens Hospital, Los Angeles | Cardiovascular and Cerebrovascular Disease | |
| Secondhand smoke, past smoking, diet, novel biomarkers and breast cancer metastasis. | 2019 (Cycle 30) | $602,000 |
| San Diego State University Research Foundation | Cancer | |
| Understanding the mechanisms of perineural invasion in oral cancer | 2019 (Cycle 30) | $499,510 |
| University of California, San Francisco | Oral Disease and Dental Health | |
| Role of the E3 ubiquitin ligase RNF125 in pancreatic cancer | 2019 (Cycle 30) | $780,000 |
| Sanford Burnham Prebys Medical Discovery Institute | Cancer | |
| Quantitative and Scalable Tumor Growth Map for Complex Genotypes in Lung Cancer | 2019 (Cycle 30) | $626,000 |
| Stanford University | Cancer | |
| The Effects of Electronic Hookah on Endothelial Cell Function: The Role of Nicotine | 2019 (Cycle 30) | $498,419 |
| University of California, Los Angeles | Cardiovascular and Cerebrovascular Disease | |
| Pilot Investigation of Tobacco and Cannabis Contaminants in an Urban Natural Reserve | 2019 (Cycle 30) | $602,000 |
| San Diego State University Research Foundation | Environmental Exposure/Toxicology | |
| Impact of JUUL Use on Lung Physiologic and Immune Health and Systemic Inflammation | 2019 (Cycle 30) | $567,587 |
| Veterans Medical Research Foundation | Pulmonary Disease | |
2019 (Cycle 29)
| Combination immuno and metabolic therapy for early-stage lung adenocarcinoma | 2019 (Cycle 29) | $499,756 |
| University of California, Los Angeles | Cancer | |
| Reducing Disparities by Integrating Tobacco Cessation into HIV Care | 2019 (Cycle 29) | $497,790 |
| University of California, San Diego | Tobacco-Use Prevention and Cessation | |
| The Effect of Combined Tobacco and Marijuana Use on Pulmonary Function: A Pilot Study | 2019 (Cycle 29) | $586,820 |
| University of California, San Francisco | Pulmonary Disease | |
| A digital mixed methods evaluation of university tobacco-free policies | 2019 (Cycle 29) | $540,733 |
| CSU Fullerton Auxiliary Services Corporation | State and Local Tobacco Control Policy Research | |
| Impact of Smoking on Myeloproliferative Neoplasms | 2019 (Cycle 29) | $488,330 |
| University of California, Irvine | Cancer | |
| Mechanistic basis of arrhythmogenic cardiac alternans following tobacco smoke exposure | 2019 (Cycle 29) | $500,000 |
| University of California, Davis | Cardiovascular and Cerebrovascular Disease | |
| The role of Eukaryotic Translation Elongation Factor 1 Alpha 2 in cardiac function and disease | 2019 (Cycle 29) | $498,058 |
| University of California, San Diego | Cardiovascular and Cerebrovascular Disease | |
| Smoking in Bipolar Disorder: Contribution of Sensory and Cognitive Brain Functions and Genomics | 2019 (Cycle 29) | $498,582 |
| University of California, Irvine | Neuroscience of Nicotine Addiction and Treatment | |
| Engineered Proteins to Reverse Chitin Buildup and Fibrotic Lung Disease | 2019 (Cycle 29) | $494,868 |
| University of California, San Francisco | Pulmonary Disease | |
| Tobacco cessation and prevention for underserved Arab Americans: A pilot study | 2019 (Cycle 29) | $635,235 |
| PIRE California, Inc. | Tobacco-Use Prevention and Cessation | |
| Social Media-based Treatment: Engaging Sexual and Gender Minority Smokers | 2019 (Cycle 29) | $499,397 |
| University of California, San Francisco | Tobacco-Use Prevention and Cessation | |
| Digital Surveillance to Identify Alternative & Emerging Tobacco Industry Mobilization and Influence | 2019 (Cycle 29) | $495,186 |
| University of California, San Diego | State and Local Tobacco Control Policy Research | |
| Promoting Tumor Suppressor Activity in Pancreatic Cancer | 2019 (Cycle 29) | $498,469 |
| University of California, San Diego | Cancer | |
| Evaluating a protocol for the removal of thirdhand smoke in homes of former smokers | 2019 (Cycle 29) | $493,225 |
| University of California, Berkeley | Environmental Exposure/Toxicology | |
| A Novel Mouse Model of Thirdhand Smoke-Induced Childhood Leukemia | 2019 (Cycle 29) | $542,378 |
| University of California, San Francisco | Environmental Exposure/Toxicology | |
| Understanding how submucosal gland myoepithelial cells respond to cigarette smoke | 2019 (Cycle 29) | $499,678 |
| University of California, Los Angeles | Cancer | |
| Mitigating pro-inflammatory non-agonist molecules from tobacco smoke | 2019 (Cycle 29) | $482,840 |
| University of California, Los Angeles | Environmental Exposure/Toxicology | |
| Models for prospective studies of marijuana's cardiac effects | 2019 (Cycle 29) | $499,316 |
| University of California, San Francisco | Cardiovascular and Cerebrovascular Disease | |
| Immune mechanisms of FLASH radiotherapy: a new paradigm for lung cancer cure | 2019 (Cycle 29) | $628,421 |
| Stanford University | Cancer | |
| Novel Pharmacotherapy Approaches in Smokers with Serious Mental Illness | 2019 (Cycle 29) | $498,794 |
| University of California, San Diego | Tobacco-Use Prevention and Cessation | |
| Do E-Cigarettes Increase Risk for Sudden Death? Focus on the QT Interval | 2019 (Cycle 29) | $497,148 |
| University of California, Los Angeles | Cardiovascular and Cerebrovascular Disease | |
| VIP smoking cessation intervention for adults with serious mental illness | 2019 (Cycle 29) | $495,156 |
| University of California, San Francisco | Tobacco-Use Prevention and Cessation | |
2019 (Cycle 28)
| Local Cannabis Regulation: What have we learned from tobacco | 2019 (Cycle 28) | $455,992 |
| Public Health Institute | State and Local Tobacco Control Policy Research | |
| Randomized Crossover Clinical Trial of Unfiltered Cigarettes | 2019 (Cycle 28) | $660,403 |
| San Diego State University Research Foundation | Tobacco-Use Prevention and Cessation | |
| Dissecting Cardiovascular Effects of E-Cigarettes | 2019 (Cycle 28) | $535,618 |
| University of California, Los Angeles | Cardiovascular and Cerebrovascular Disease | |
| Deciphering p53 Programs in Lung Cancer Suppression | 2019 (Cycle 28) | $611,377 |
| Stanford University | Cancer | |
| CONNECT: Smoking Cessation and Lung Cancer Screening | 2019 (Cycle 28) | $499,241 |
| University of California, San Francisco | Tobacco-Use Prevention and Cessation | |
| Evaluating Relationship of Cannabis use & Tobacco Cessation | 2019 (Cycle 28) | $561,591 |
| Veterans Medical Research Foundation | Tobacco-Use Prevention and Cessation | |
| Tobacco & cannabis use among sexual & gender minorities | 2019 (Cycle 28) | $486,782 |
| University of California, Los Angeles | Tobacco-Use Prevention and Cessation | |
| Targeting invadopodia in head and neck cancer metastasis | 2019 (Cycle 28) | $498,393 |
| University of California, San Diego | Cancer | |
| Effect of nicotine exposure on mitochondria in myocytes | 2019 (Cycle 28) | $500,000 |
| University of California, San Diego | Cardiovascular Disease | |
| Social Cognition and Tobacco Craving in HIV Patients | 2019 (Cycle 28) | $497,598 |
| University of California, San Diego | Tobacco-Use Prevention and Cessation | |
| Interventions to reduce tobacco use among homeless women | 2019 (Cycle 28) | $496,848 |
| University of California, San Francisco | Tobacco-Use Prevention and Cessation | |
| Effect of Nicotine, E-Cigarette and Cannabinoids on the Gut | 2019 (Cycle 28) | $497,923 |
| University of California, San Diego | State and Local Tobacco Control Policy Research | |
| Treating NSCLC with Next-Gen RNAi Therapeutics Target | 2019 (Cycle 28) | $498,126 |
| University of California, San Diego | Cancer | |
| Tobacco and Cannabis: Effects on Fetal Development in Rats | 2019 (Cycle 28) | $602,000 |
| San Diego State University Research Foundation | Neuroscience of Nicotine Addiction and Treatment | |
2018 (Cycle 27)
| Tracking Tobacco Waste to Increase College Policy Engagement | 2018 (Cycle 27) | $607,533 |
| University Auxiliary and Research Services Corporation | State and Local Tobacco Control Policy Research | |
| Uncovering Therapeutic Specificity for Defined Oncogenic KRAS | 2018 (Cycle 27) | $636,561 |
| Stanford University | Cancer | |
| Update KiR: An Evidence-Based Program Reducing Teen Tobacco Use | 2018 (Cycle 27) | $526,924 |
| Education Training and Research Associates, Inc. | Tobacco-Use Prevention and Cessation | |
| Comprehensive Program to Reduce Tobacco-Related Health Disparities | 2018 (Cycle 27) | $498,823 |
| University of California, San Francisco | Tobacco-Use Prevention and Cessation | |
| WeChat to Quit: Engage Chinese Patients to Stop Smoking | 2018 (Cycle 27) | $484,086 |
| Chinese Community Health Resource Center | Tobacco-Use Prevention and Cessation | |
| Remediation of Tobacco Toxicants Polluting Low-Income Multiunit Homes | 2018 (Cycle 27) | $601,884 |
| San Diego State University Research Foundation | Environmental Exposure/Toxicology | |
| Determining a role for long noncoding RNAs in smoke-induced COPD | 2018 (Cycle 27) | $519,043 |
| University of California, Santa Cruz | Pulmonary Disease | |
| Text Messaging-Based Smoking Cessation Program for Homeless | 2018 (Cycle 27) | $687,334 |
| RAND Corporation | Cardiovascular and Cerebrovascular Disease | |
| Understanding Nicotine and Smoking Cessation Drugs: Release | 2018 (Cycle 27) | $660,000 |
| California Institute of Technology | Neuroscience of Nicotine Addiction and Treatment | |
| Prenatal exposure of cigarette smoke impacts cardiac regeneration | 2018 (Cycle 27) | $596,161 |
| Stanford University | Cardiovascular and Cerebrovascular Disease | |
| Whole Genome RNAseq Studies of Blood in Smokers vs Nonsmokers | 2018 (Cycle 27) | $400,000 |
| University of California, Davis | Cardiovascular and Cerebrovascular Disease | |
| Tumor heterogeneity and cooperativity drive metastasis in RC | 2018 (Cycle 27) | $499,678 |
| University of California, Los Angeles | Environmental Exposure/Toxicology | |
| Fetal Nicotine Exposure Alters Bone Marrow Stem Cell Function | 2018 (Cycle 27) | $563,438 |
| LA Biomedical Research Institute at Harbor-UCLA Medical Center | Neuroscience of Nicotine Addiction and Treatment | |
| Effects of e-cigarette aerosol on oral epithelial cell metabolism | 2018 (Cycle 27) | $483,801 |
| University of California, Los Angeles | Oral Disease and Dental Health | |
| Infrared Imaging Methods for the Detection and Diagnosis of cavities | 2018 (Cycle 27) | $496,112 |
| University of California, San Francisco | Oral Disease and Dental Health | |
2017 (Cycle 26)
| Does secondhand smoke induce epigenetic changes? | 2017 (Cycle 26) | $392,100 |
| University of Southern California | Environmental Exposure/Toxicology | |
| Regulation of F2RL3/PAR4 Expression and Function by Methylat | 2017 (Cycle 26) | $341,978 |
| University of California, San Diego | Environmental Exposure/Toxicology | |
| ADOLESCENT NICOTINE AND CANNABINOID EXPOSURE ON NICOTINE DEPENDENCE | 2017 (Cycle 26) | $300,000 |
| University of California, Irvine | Neuroscience of Nicotine Addiction and Treatment | |
| Nicotine and Epigenetic Transgenerational Risk of Abdominal Aortic Aneurysm | 2017 (Cycle 26) | $326,640 |
| Palo Alto Veterans Institute For Research | Cardiovascular Disease | |
| Visualizing Neural Activity Dynamics During Nicotine Reward | 2017 (Cycle 26) | $266,321 |
| University of California, Berkeley | Neuroscience of Nicotine Addiction and Treatment | |
| E-cigarette chemical effects on endothelial function | 2017 (Cycle 26) | $380,870 |
| Stanford University | Cardiovascular Disease | |
| Assessing the impact of heat-not-burn and next-generation vaping products | 2017 (Cycle 26) | $448,619 |
| Lawrence Berkeley National Laboratory | Environmental Exposure/Toxicology | |
| Empower Korean Families to End Tobacco Use & Smoke Exposure | 2017 (Cycle 26) | $330,454 |
| University of California, San Francisco | Tobacco-Related Health Disparities | |
| Immunotheranostic MPI for Early Diagnosis of Tobacco-Related Lung Cancer | 2017 (Cycle 26) | $319,604 |
| University of California, Berkeley | Early Diagnosis of Tobacco-Related Cancer | |
| Tobacco industry influence on the video game industry | 2017 (Cycle 26) | $299,582 |
| University of California, San Francisco | Tobacco-Use Prevention and Cessation | |
| Effects of Thirdhand Smoke Exposure on the Microbiome of Young Children | 2017 (Cycle 26) | $361,180 |
| San Diego State University Research Foundation | Environmental Exposure/Toxicology | |
| American Indian Youth: PSA, Photovoice & Digital Storytelling | 2017 (Cycle 26) | $387,041 |
| University of Southern California | Tobacco-Use Prevention and Cessation | |
| A Molecular Approach for Early Diagnosis of Lung Cancer | 2017 (Cycle 26) | $376,800 |
| Stanford University | Early Diagnosis of Tobacco-Related Cancer | |
| In-utero smoke exposure and epigenetic activation of GFI1-family oncogenes | 2017 (Cycle 26) | $299,337 |
| University of California, San Francisco | Early Diagnosis of Tobacco-Related Cancer | |
| Chronic Electronic Cigarette Use and Accelerated Skeletal Muscle Aging | 2017 (Cycle 26) | $320,000 |
| University of California, San Diego | Cardiovascular Disease | |
| Understanding the Mechanisms of Smoking Induced Squamous Lung Cancer | 2017 (Cycle 26) | $299,718 |
| University of California, Los Angeles | Early Diagnosis of Tobacco-Related Cancer | |
| E-cigarette and Tobacco Use Prevention for Deaf and Hard-of-Hearing Youth | 2017 (Cycle 26) | $299,816 |
| University of California, Los Angeles | Tobacco-Related Health Disparities | |
| Development of the COPD Phenotype:Role of the IL-22/IL-22R1 Axis | 2017 (Cycle 26) | $299,333 |
| University of California, Davis | Pulmonary Disease | |
| Inflammatory cardiovascular disease induced by autonomic effects of e-cigs | 2017 (Cycle 26) | $320,000 |
| University of California, San Diego | Socio-cultural, Behavioral and Psychological | |
2016 (Cycle 25)
| Early Nicotine Exposure Re-Wires Neural Circuits | 2016 (Cycle 25) | $299,335 |
| University of California, San Diego | Neuroscience of Nicotine Addiction and Treatment | |
| Silicone Wristbands: Personal Samplers for Tobacco Toxicants | 2016 (Cycle 25) | $360,608 |
| San Diego State University Research Foundation | Environmental Exposure/Toxicology | |
| Investigating the carcinogenicity of e-cig | 2016 (Cycle 25) | $396,000 |
| University of Southern California | Environmental Exposure/Toxicology | |
| Metabolic and Carcinogen Effect of Electronic Cigarettes | 2016 (Cycle 25) | $384,454 |
| Friends Research Institute, Inc. | Environmental Exposure/Toxicology | |
| A smoke-free home intervention in supportive housing | 2016 (Cycle 25) | $319,871 |
| University of California, San Francisco | Tobacco-Use Prevention and Cessation | |
| Evaluation of tobacco and e-cigarette genotoxicity | 2016 (Cycle 25) | $408,000 |
| Beckman Research Institute of the City of Hope | Environmental Exposure/Toxicology | |
| Fighting Big Tobacco with Big Data | 2016 (Cycle 25) | $229,057 |
| Stanford University | State and Local Tobacco Control Policy Research | |
| Dendritic-epithelial cells crosstalk in lung inflammation | 2016 (Cycle 25) | $300,000 |
| University of California, Irvine | Pulmonary Disease | |
| microRNA biomarkers of THS teratogenicity | 2016 (Cycle 25) | $293,205 |
| University of California, Riverside | Environmental Exposure/Toxicology | |
| Therapeutic potential of oxytocin for nicotine addiction | 2016 (Cycle 25) | $404,115 |
| University of Southern California | Neuroscience of Nicotine Addiction and Treatment | |
| E-Cigarettes and Coronary Endothelial Function in Dual Users | 2016 (Cycle 25) | $425,477 |
| Cedars-Sinai Medical Center | Cardiovascular Disease | |
| mGlu7 activators as drug candidates for nicotine dependence | 2016 (Cycle 25) | $481,721 |
| The Burnham Institute for Medical Research | Neuroscience of Nicotine Addiction and Treatment | |