TRDRP
Research Portfolio
Funding Opportunities

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Exploratory/Developmental Award

2013 (Cycle 22)
MicroRNA Therapeutics for Nicotine Addiction 2013 (Cycle 22) $250,000
University of California, San Diego Disparities /Prevention/ Cessation/ Nicotine Dependence

Prenatal Nicotine Exposure and Epigenetic Regulation of AT2R 2013 (Cycle 22) $316,000
Loma Linda University Environmental Exposure/Toxicology

Atmospheric transformations of second hand smoke 2013 (Cycle 22) $273,446
California State University, Fresno Foundation Environmental Exposure/Toxicology

Hookah, Sympathetic Nerves, and Coronary Perfusion in Humans 2013 (Cycle 22) $337,347
Cedars-Sinai Medical Center Early Diagnosis/Pathogenesis

An experimental assessment of FDA graphic warning labels 2013 (Cycle 22) $252,794
University of California, San Francisco Regulatory Science/New Products

A pilot tobacco control intervention for homeless adults 2013 (Cycle 22) $250,000
University of California, San Diego Disparities /Prevention/ Cessation/ Nicotine Dependence

2012 (Cycle 21)
TITF1 signature biomarkers for early lung cancer detection 2012 (Cycle 21) $343,830
Stanford University Early Diagnosis/Pathogenesis

Imaging SHS Deposition in the Airways of Sprague-Dawley Rats 2012 (Cycle 21) $218,999
University of California, Davis Environmental Exposure/Toxicology

Screening Smokers for Depression Using California's Helpline 2012 (Cycle 21) $219,000
University of California, San Diego Disparities /Prevention/ Cessation/ Nicotine Dependence

Oxidative Stress/Inflammation in Pulmonary Disease 2012 (Cycle 21) $415,004
Scripps Research Institute Early Diagnosis/Pathogenesis

Virtual Intervention for Lung Cancer Stigma 2012 (Cycle 21) $219,000
University of California, San Francisco Disparities /Prevention/ Cessation/ Nicotine Dependence

Improving Tobacco Dependence Treatment in the Addictions 2012 (Cycle 21) $219,000
University of California, San Francisco Disparities /Prevention/ Cessation/ Nicotine Dependence

Cigarette Producer Responsibility Project 2012 (Cycle 21) $239,401
Cigarette Butt Pollution Project Regulatory Science/New Products

Identifying new markers for diagnosis and treatment of SCLC 2012 (Cycle 21) $219,000
University of California, San Francisco Early Diagnosis/Pathogenesis

2011 (Cycle 20)
Design of Complement Inhibitors for Cardiovascular Disease 2011 (Cycle 20) $250,000
University of California, Riverside Cardiovascular Disease

Genome-wide mapping of smoke-induced DNA damage and mutation 2011 (Cycle 20) $420,000
Beckman Research Institute of the City of Hope Cancer

Nicotine Receptor in Nicotine Dependence 2011 (Cycle 20) $405,000
California Institute of Technology Nicotine Dependence

Role for fibroblasts in the chronic immune response in COPD 2011 (Cycle 20) $250,000
University of California, San Francisco Pulmonary Disease

Leveraging Adjuvants for Improved Nicotine Vaccines 2011 (Cycle 20) $421,413
Scripps Research Institute Tobacco-Use Prevention and Cessation

Sirtuin deacetylase and RAS-dependent cancers 2011 (Cycle 20) $420,000
Beckman Research Institute of the City of Hope Cancer

Tobacco-use by LGBTQ youth: prevalence and correlates 2011 (Cycle 20) $304,650
Education Training and Research Associates, Inc. Tobacco-Use Prevention and Cessation

The effects of stereotype threat on smoking behavior 2011 (Cycle 20) $248,932
University of California, Los Angeles Public Health, Public Policy, and Economics

Genome-wide mapping of smoke-induced DNA damage and mutation 2011 (Cycle 20) $339,619
University of Southern California Cancer

Effect of Smoking on Vascular Calcification in COPD 2011 (Cycle 20) $352,361
LA Biomedical Research Institute at Harbor-UCLA Medical Center Cardiovascular Disease

Electronic Cigarettes: Are They Safe? 2011 (Cycle 20) $250,000
University of California, Riverside General Biomedical Science

Tobacco Cessation Interventions for Mental Health Patients 2011 (Cycle 20) $353,356
Veterans Medical Research Foundation Tobacco-Use Prevention and Cessation

Selective Lung Cancer Treatment with Small Conditional RNAs 2011 (Cycle 20) $410,000
California Institute of Technology Cancer

SMART:Sequential Motion Adaptation to Improve Lung Cancer RT 2011 (Cycle 20) $250,000
University of California, Los Angeles Cancer

Lung cancer detection by methylation-preserving PCR 2011 (Cycle 20) $324,825
University of Southern California Cancer

Proteomic Mapping of Human Lung Tumor Endothelium 2011 (Cycle 20) $487,500
Proteomics Research Institute for Systems Medicine Cancer

2010 (Cycle 19)
Apoptotic cell clearance and Tobacco Induced COPD 2010 (Cycle 19) $250,000
University of California, San Diego Pulmonary Disease

Dynamic Imaging of Sodium Channels in Metastatic Lung Cancer 2010 (Cycle 19) $400,000
Stanford University Cancer

Secondhand Smoke and Human Prenatal Development 2010 (Cycle 19) $250,000
University of California, Riverside General Biomedical Science

Targeted nanodelivery of anti-inflammatory drugs 2010 (Cycle 19) $482,749
Proteomics Research Institute for Systems Medicine Pulmonary Disease

Using Adultborn Neurons to Combat Nicotine Relapse 2010 (Cycle 19) $250,000
University of California, San Diego Nicotine Dependence

Enhancing mTOR-targeted lung cancer therapy 2010 (Cycle 19) $474,750
Scripps Research Institute Cancer

Chromosome 9p21.3 in tobacco related vascular diseases 2010 (Cycle 19) $360,724
Stanford University Cardiovascular Disease

Novel Susceptibility Factors in Lung Cancer Evolution 2010 (Cycle 19) $400,000
Stanford University Cancer

Effects of THS on cell and molecular mechanisms of healing 2010 (Cycle 19) $250,000
University of California, Riverside General Biomedical Science

A Family Intervention to Reduce Smoking in Vietnamese Men 2010 (Cycle 19) $249,977
University of California, San Francisco Tobacco-Use Prevention and Cessation

Menthol Cigarette Smokers:nAChR Levels and Treatment Effects 2010 (Cycle 19) $269,460
Brentwood Biomedical Research Institute Nicotine Dependence

Genotoxicity of Thirdhand Smoke and Aged Secondhand Smoke 2010 (Cycle 19) $427,267
Lawrence Berkeley National Laboratory General Biomedical Science

Understanding nicotinic receptor subtype specificity 2010 (Cycle 19) $361,036
California Institute of Technology Nicotine Dependence

Fbxo2: a master regulator of lung cancer metastasis? 2010 (Cycle 19) $477,500
The Burnham Institute for Medical Research Cancer

SOX-2 knockdown in stem cells prevents lung tumor recurrence 2010 (Cycle 19) $474,750
Scripps Research Institute Cancer

2009 (Cycle 18)
Sympathoexcitatory Effect of Tobacco in Premenopausal Women 2009 (Cycle 18) $245,492
University of California, Los Angeles Cardiovascular Disease

Informing Smoking Interventions for CA University Students 2009 (Cycle 18) $353,950
Veterans Medical Research Foundation Tobacco-Use Prevention and Cessation

Exploring retailer abandonment of tobacco sales 2009 (Cycle 18) $250,000
University of California, San Francisco Public Health, Public Policy, and Economics

Nicotine and Abdominal Aortic Aneurysms 2009 (Cycle 18) $400,534
Stanford University Cardiovascular Disease

An atypical nicotine receptor: target for anti-angiogenics? 2009 (Cycle 18) $385,707
Stanford University Cardiovascular Disease

Low Frequency Smoking Among Latinos 2009 (Cycle 18) $249,863
University of California, San Diego Tobacco-Use Prevention and Cessation

Immunotargeting lung cancer 2009 (Cycle 18) $487,500
Proteomics Research Institute for Systems Medicine Cancer

Tobacco Industry Influence on Policy Making 2009 (Cycle 18) $248,003
University of California, San Francisco Public Health, Public Policy, and Economics

Corepressors, TZDs, and tobacco-induced lung inflammation 2009 (Cycle 18) $249,587
University of California, Davis Pulmonary Disease

Nicotine/norharmane as a model of tobacco dependence 2009 (Cycle 18) $248,962
University of California, Irvine Nicotine Dependence

A new approach to anti-angiogenic therapy in lung cancer 2009 (Cycle 18) $407,935
Stanford University Cancer

Novel Drugs for Lung Cancer 2009 (Cycle 18) $354,000
Veterans Medical Research Foundation Cancer

Quantitative Proteomics of Oral Precancer Progression 2009 (Cycle 18) $249,605
University of California, Los Angeles Cancer

Modeling and mapping changes in tobacco outlet density 2009 (Cycle 18) $388,520
Stanford University Public Health, Public Policy, and Economics

Pro-inflammatory sPLA2, integrins, and smoking 2009 (Cycle 18) $250,000
University of California, Davis Cardiovascular Disease

Notch promotes arteriogenesis in smoke-related limb ischemia 2009 (Cycle 18) $250,000
University of California, San Francisco Cardiovascular Disease

Bar Interventions to Decrease Young Adult and LGBT Smoking 2009 (Cycle 18) $249,459
University of California, San Francisco Tobacco-Use Prevention and Cessation

Role of EphA3 receptor mutations in lung cancer 2009 (Cycle 18) $477,500
The Burnham Institute for Medical Research Cancer

Developing A Menthol-Centric Smoking Cessation Intervention 2009 (Cycle 18) $353,750
Charles R. Drew University of Medicine & Science Tobacco-Use Prevention and Cessation

Genome-specific synthetic lethal targeting in lung cancer 2009 (Cycle 18) $400,000
Stanford University Cancer

Active and Passive Smoking and Risk of Colorectal Cancer 2009 (Cycle 18) $324,035
Cancer Prevention Institute of California Epidemiology

Cigarette Smoke Exposure In Utero: Neonatal Immunity 2009 (Cycle 18) $250,000
University of California, San Diego Pulmonary Disease

The effect of nicotine on airway inflammation 2009 (Cycle 18) $406,250
University of Southern California Pulmonary Disease

Lung Development, Tobacco Smoke and Sensitivity to Infection 2009 (Cycle 18) $250,000
University of California, Davis Pulmonary Disease

Novel Therapy Sensitization Strategy for Lung Cancer 2009 (Cycle 18) $450,000
Torrey Pines Institute for Molecular Studies Cancer

Economic impact of smoking for persons with mental disorders 2009 (Cycle 18) $249,933
University of California, San Francisco Tobacco-Use Prevention and Cessation

Toxicity of Harm Reduction Products on Human Development 2009 (Cycle 18) $250,000
University of California, Riverside General Biomedical Science

Autophagy and cell fate in K-Ras mutant lung cancer cells 2009 (Cycle 18) $250,000
University of California, San Francisco Cancer

Does Maternal Smoking Impair Neonatal Control of Breathing? 2009 (Cycle 18) $250,000
University of California, Los Angeles Pulmonary Disease

Regulation of biased PAR1 signaling by ubiquitination 2009 (Cycle 18) $250,000
University of California, San Diego General Biomedical Science

DNA Adducts Arising from Tobacco-derived N-nitrosamines 2009 (Cycle 18) $250,000
University of California, Riverside General Biomedical Science