TRDRP
Research Portfolio
Funding Opportunities

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Exploratory/Developmental Award

2014 (Cycle 23)
Menthol Cigarette Smoking & Neuroinflammation 2014 (Cycle 23) $235,010
Brentwood Biomedical Research Institute Disparities /Prevention/ Cessation/ Nicotine Dependence

CTCs for early detection and characterization of lung cancer 2014 (Cycle 23) $351,236
SRI International Early Diagnosis/Pathogenesis

Indoor vaping: chemical characterization and health impacts 2014 (Cycle 23) $299,011
Lawrence Berkeley National Laboratory Environmental Exposure/Toxicology

Subcellular pharmacokinetics of nicotinic compounds 2014 (Cycle 23) $316,350
California Institute of Technology Disparities /Prevention/ Cessation/ Nicotine Dependence

Treatment Engagement for Outpatient Smokers with Psychiatric 2014 (Cycle 23) $264,417
Veterans Medical Research Foundation Disparities /Prevention/ Cessation/ Nicotine Dependence

Impact of electronic cigarettes on cardiac risk 2014 (Cycle 23) $264,812
University of California, Los Angeles Regulatory Science/New Products

Characterization of emissions from electronic cigarettes 2014 (Cycle 23) $230,750
University of California, Los Angeles Environmental Exposure/Toxicology

2013 (Cycle 22)
A pilot tobacco control intervention for homeless adults 2013 (Cycle 22) $250,000
University of California, San Diego Disparities /Prevention/ Cessation/ Nicotine Dependence

Atmospheric transformations of second hand smoke 2013 (Cycle 22) $273,446
California State University, Fresno Foundation Environmental Exposure/Toxicology

MicroRNA Therapeutics for Nicotine Addiction 2013 (Cycle 22) $250,000
University of California, San Diego Disparities /Prevention/ Cessation/ Nicotine Dependence

Hookah, Sympathetic Nerves, and Coronary Perfusion in Humans 2013 (Cycle 22) $337,347
Cedars-Sinai Medical Center Early Diagnosis/Pathogenesis

An experimental assessment of FDA graphic warning labels 2013 (Cycle 22) $252,794
University of California, San Francisco Regulatory Science/New Products

Prenatal Nicotine Exposure and Epigenetic Regulation of AT2R 2013 (Cycle 22) $316,000
Loma Linda University Environmental Exposure/Toxicology

2012 (Cycle 21)
TITF1 signature biomarkers for early lung cancer detection 2012 (Cycle 21) $343,799
Stanford University Early Diagnosis/Pathogenesis

Screening Smokers for Depression Using California's Helpline 2012 (Cycle 21) $219,000
University of California, San Diego Disparities /Prevention/ Cessation/ Nicotine Dependence

Cigarette Producer Responsibility Project 2012 (Cycle 21) $255,901
Cigarette Butt Pollution Project Regulatory Science/New Products

Virtual Intervention for Lung Cancer Stigma 2012 (Cycle 21) $219,000
University of California, San Francisco Disparities /Prevention/ Cessation/ Nicotine Dependence

Identifying new markers for diagnosis and treatment of SCLC 2012 (Cycle 21) $219,000
University of California, San Francisco Early Diagnosis/Pathogenesis

Oxidative Stress/Inflammation in Pulmonary Disease 2012 (Cycle 21) $409,427
Scripps Research Institute Early Diagnosis/Pathogenesis

Improving Tobacco Dependence Treatment in the Addictions 2012 (Cycle 21) $219,000
University of California, San Francisco Disparities /Prevention/ Cessation/ Nicotine Dependence

Imaging SHS Deposition in the Airways of Sprague-Dawley Rats 2012 (Cycle 21) $218,999
University of California, Davis Environmental Exposure/Toxicology

2011 (Cycle 20)
Tobacco Cessation Interventions for Mental Health Patients 2011 (Cycle 20) $343,173
Veterans Medical Research Foundation Tobacco-Use Prevention and Cessation

Genome-wide mapping of smoke-induced DNA damage and mutation 2011 (Cycle 20) $80,381
Beckman Research Institute of the City of Hope Cancer

Role for fibroblasts in the chronic immune response in COPD 2011 (Cycle 20) $250,000
University of California, San Francisco Pulmonary Disease

SMART:Sequential Motion Adaptation to Improve Lung Cancer RT 2011 (Cycle 20) $250,000
University of California, Los Angeles Cancer

Leveraging Adjuvants for Improved Nicotine Vaccines 2011 (Cycle 20) $421,413
Scripps Research Institute Tobacco-Use Prevention and Cessation

Design of Complement Inhibitors for Cardiovascular Disease 2011 (Cycle 20) $250,000
University of California, Riverside Cardiovascular Disease

Tobacco-use by LGBTQ youth: prevalence and correlates 2011 (Cycle 20) $304,650
Education Training and Research Associates, Inc. Tobacco-Use Prevention and Cessation

Electronic Cigarettes: Are They Safe? 2011 (Cycle 20) $280,000
University of California, Riverside General Biomedical Science

The effects of stereotype threat on smoking behavior 2011 (Cycle 20) $263,932
University of California, Los Angeles Public Health, Public Policy, and Economics

Nicotine Receptor in Nicotine Dependence 2011 (Cycle 20) $404,662
California Institute of Technology Nicotine Dependence

Genome-wide mapping of smoke-induced DNA damage and mutation 2011 (Cycle 20) $335,986
University of Southern California Cancer

Effect of Smoking on Vascular Calcification in COPD 2011 (Cycle 20) $352,361
LA Biomedical Research Institute at Harbor-UCLA Medical Center Cardiovascular Disease

Lung cancer detection by methylation-preserving PCR 2011 (Cycle 20) $324,325
University of Southern California Cancer

Sirtuin deacetylase and RAS-dependent cancers 2011 (Cycle 20) $420,000
Beckman Research Institute of the City of Hope Cancer

Proteomic Mapping of Human Lung Tumor Endothelium 2011 (Cycle 20) $487,182
Proteomics Research Institute for Systems Medicine Cancer

2010 (Cycle 19)
Effects of THS on cell and molecular mechanisms of healing 2010 (Cycle 19) $250,000
University of California, Riverside General Biomedical Science

Menthol Cigarette Smokers:nAChR Levels and Treatment Effects 2010 (Cycle 19) $317,525
Brentwood Biomedical Research Institute Nicotine Dependence

Secondhand Smoke and Human Prenatal Development 2010 (Cycle 19) $280,000
University of California, Riverside General Biomedical Science

Apoptotic cell clearance and Tobacco Induced COPD 2010 (Cycle 19) $56,857
University of California, San Diego Pulmonary Disease

SOX-2 knockdown in stem cells prevents lung tumor recurrence 2010 (Cycle 19) $473,879
Scripps Research Institute Cancer

Understanding nicotinic receptor subtype specificity 2010 (Cycle 19) $361,036
California Institute of Technology Nicotine Dependence

Enhancing mTOR-targeted lung cancer therapy 2010 (Cycle 19) $473,879
Scripps Research Institute Cancer

A Family Intervention to Reduce Smoking in Vietnamese Men 2010 (Cycle 19) $288,421
University of California, San Francisco Tobacco-Use Prevention and Cessation

Novel Susceptibility Factors in Lung Cancer Evolution 2010 (Cycle 19) $400,000
Stanford University Cancer

Targeted nanodelivery of anti-inflammatory drugs 2010 (Cycle 19) $482,749
Proteomics Research Institute for Systems Medicine Pulmonary Disease

Dynamic Imaging of Sodium Channels in Metastatic Lung Cancer 2010 (Cycle 19) $400,000
Stanford University Cancer

Fbxo2: a master regulator of lung cancer metastasis? 2010 (Cycle 19) $477,500
The Burnham Institute for Medical Research Cancer

Genotoxicity of Thirdhand Smoke and Aged Secondhand Smoke 2010 (Cycle 19) $427,204
Lawrence Berkeley National Laboratory General Biomedical Science

Using Adultborn Neurons to Combat Nicotine Relapse 2010 (Cycle 19) $250,000
University of California, San Diego Nicotine Dependence

2009 (Cycle 18)
Quantitative Proteomics of Oral Precancer Progression 2009 (Cycle 18) $249,605
University of California, Los Angeles Cancer

Pro-inflammatory sPLA2, integrins, and smoking 2009 (Cycle 18) $250,000
University of California, Davis Cardiovascular Disease

Low Frequency Smoking Among Latinos 2009 (Cycle 18) $249,863
University of California, San Diego Tobacco-Use Prevention and Cessation

The effect of nicotine on airway inflammation 2009 (Cycle 18) $402,991
University of Southern California Pulmonary Disease

Does Maternal Smoking Impair Neonatal Control of Breathing? 2009 (Cycle 18) $250,000
University of California, Los Angeles Pulmonary Disease

DNA Adducts Arising from Tobacco-derived N-nitrosamines 2009 (Cycle 18) $250,000
University of California, Riverside General Biomedical Science

Role of EphA3 receptor mutations in lung cancer 2009 (Cycle 18) $477,500
The Burnham Institute for Medical Research Cancer

Corepressors, TZDs, and tobacco-induced lung inflammation 2009 (Cycle 18) $249,587
University of California, Davis Pulmonary Disease

A new approach to anti-angiogenic therapy in lung cancer 2009 (Cycle 18) $407,935
Stanford University Cancer

Sympathoexcitatory Effect of Tobacco in Premenopausal Women 2009 (Cycle 18) $245,492
University of California, Los Angeles Cardiovascular Disease

Exploring retailer abandonment of tobacco sales 2009 (Cycle 18) $250,000
University of California, San Francisco Public Health, Public Policy, and Economics

Novel Therapy Sensitization Strategy for Lung Cancer 2009 (Cycle 18) $450,000
Torrey Pines Institute for Molecular Studies Cancer

Toxicity of Harm Reduction Products on Human Development 2009 (Cycle 18) $310,000
University of California, Riverside General Biomedical Science

Active and Passive Smoking and Risk of Colorectal Cancer 2009 (Cycle 18) $323,850
Cancer Prevention Institute of California Epidemiology

Nicotine and Abdominal Aortic Aneurysms 2009 (Cycle 18) $400,534
Stanford University Cardiovascular Disease

Modeling and mapping changes in tobacco outlet density 2009 (Cycle 18) $387,418
Stanford University Public Health, Public Policy, and Economics

Notch promotes arteriogenesis in smoke-related limb ischemia 2009 (Cycle 18) $250,000
University of California, San Francisco Cardiovascular Disease

Immunotargeting lung cancer 2009 (Cycle 18) $487,500
Proteomics Research Institute for Systems Medicine Cancer

Autophagy and cell fate in K-Ras mutant lung cancer cells 2009 (Cycle 18) $250,000
University of California, San Francisco Cancer

Regulation of biased PAR1 signaling by ubiquitination 2009 (Cycle 18) $279,941
University of California, San Diego General Biomedical Science

Bar Interventions to Decrease Young Adult and LGBT Smoking 2009 (Cycle 18) $244,596
University of California, San Francisco Tobacco-Use Prevention and Cessation

Developing A Menthol-Centric Smoking Cessation Intervention 2009 (Cycle 18) $374,975
Charles R. Drew University of Medicine & Science Tobacco-Use Prevention and Cessation

Nicotine/norharmane as a model of tobacco dependence 2009 (Cycle 18) $263,962
University of California, Irvine Nicotine Dependence

Novel Drugs for Lung Cancer 2009 (Cycle 18) $353,998
Veterans Medical Research Foundation Cancer

Informing Smoking Interventions for CA University Students 2009 (Cycle 18) $352,060
Veterans Medical Research Foundation Tobacco-Use Prevention and Cessation

An atypical nicotine receptor: target for anti-angiogenics? 2009 (Cycle 18) $385,707
Stanford University Cardiovascular Disease

Lung Development, Tobacco Smoke and Sensitivity to Infection 2009 (Cycle 18) $280,000
University of California, Davis Pulmonary Disease

Economic impact of smoking for persons with mental disorders 2009 (Cycle 18) $246,701
University of California, San Francisco Tobacco-Use Prevention and Cessation

Genome-specific synthetic lethal targeting in lung cancer 2009 (Cycle 18) $400,000
Stanford University Cancer

Cigarette Smoke Exposure In Utero: Neonatal Immunity 2009 (Cycle 18) $265,000
University of California, San Diego Pulmonary Disease