Research Portfolio

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Nicotine Dependence

2014 (Cycle 23)
Translational Nicotine Research Group 2014 (Cycle 23) $5,000
University of California, Los Angeles Special Projects

2013 (Cycle 22)
Nicotinic Acetylcholine Receptor-Based Therapeutics 2013 (Cycle 22) $5,000
Caplital Meeting Planning Special Projects

2011 (Cycle 20)
Nicotine Receptor in Nicotine Dependence 2011 (Cycle 20) $404,642
California Institute of Technology Exploratory/Developmental Award

The Role of Alpha2 nAChR Subtypes in Nicotine Withdrawal 2011 (Cycle 20) $135,000
University of California, Los Angeles Postdoctoral Fellowship Awards

Role of mGluR7 in nicotine dependence 2011 (Cycle 20) $270,000
University of California, San Diego New Investigator Awards

2010 (Cycle 19)
Using Adultborn Neurons to Combat Nicotine Relapse 2010 (Cycle 19) $250,000
University of California, San Diego Exploratory/Developmental Award

Understanding nicotinic receptor subtype specificity 2010 (Cycle 19) $361,036
California Institute of Technology Exploratory/Developmental Award

HRQoL in Veterans with Chronic PTSD and Tobacco Dependence 2010 (Cycle 19) $59,300
Alliant International University Dissertation Awards

Nicotinic Control of Glutamate Synapse Formation 2010 (Cycle 19) $135,000
University of California, San Diego Postdoctoral Fellowship Awards

Menthol Cigarette Smokers:nAChR Levels and Treatment Effects 2010 (Cycle 19) $317,525
Brentwood Biomedical Research Institute Exploratory/Developmental Award

AMPA Receptors and Extinction of Nicotine-Seeking Behavior 2010 (Cycle 19) $135,000
University of California, San Diego Postdoctoral Fellowship Awards

Nicotinic receptor-lynx interactions 2010 (Cycle 19) $278,797
California Institute of Technology New Investigator Awards

2009 (Cycle 18)
Impulsivity as a risk factor for nicotine dependence 2009 (Cycle 18) $270,000
University of California, San Diego New Investigator Awards

Protein networks for nicotinic acetylcholine receptors 2009 (Cycle 18) $134,878
University of California, San Diego Postdoctoral Fellowship Awards

Nicotine/norharmane as a model of tobacco dependence 2009 (Cycle 18) $263,962
University of California, Irvine Exploratory/Developmental Award

Evaluation of GABA in impulsivity and nicotine dependence 2009 (Cycle 18) $97,458
University of California, San Diego Postdoctoral Fellowship Awards

Society for Neuroscience Nicotinic Receptors Meeting II 2009 (Cycle 18) $5,000
SRI International Special Projects

Subcellular basis of nicotine-induced receptor upregulation 2009 (Cycle 18) $135,000
California Institute of Technology Postdoctoral Fellowship Awards

Prenatal Nicotine Exposure and Vascular Programming 2009 (Cycle 18) $289,840
Loma Linda University New Investigator Awards

2008 (Cycle 17)
Nicotinic receptors in nicotine addiction 2008 (Cycle 17) $634,743
California Institute of Technology Research Project Awards

Genetics and Impulsivity in Smoking Initiation 2008 (Cycle 17) $282,860
Veterans Medical Research Foundation New Investigator Awards

Nicotinic Regulation of GABAergic Inhibition/Excitation 2008 (Cycle 17) $75,000
University of California, San Diego Postdoctoral Fellowship Awards

Chronic nicotine treatment in primates; role of a6b2 nAChRs 2008 (Cycle 17) $382,500
SRI International Research Project Awards

Chronic nicotine treatment in primates; role of a6b2 nAChRs 2008 (Cycle 17) $194,628
The Parkinson's Institute Research Project Awards

Nicotinic Regulation of Neurogenesis in Adult Hippocampus 2008 (Cycle 17) $59,910
University of California, San Diego Dissertation Awards

Nicotine Self-Administration in an Animal Model 2008 (Cycle 17) $720,434
Scripps Research Institute Research Project Awards

2007 (Cycle 16)
Nicotinic Manipulation of the Hippocampus 2007 (Cycle 16) $420,000
University of California, San Diego Research Project Awards

Understanding Nicotinic Receptor Subtype Specificity 2007 (Cycle 16) $592,751
California Institute of Technology Research Project Awards

Society for Neuroscience Nicotinic Receptors Meeting 2007 (Cycle 16) $10,000
The Parkinson's Institute Special Projects

Brain nAChR Occupancy: Effect of Secondhand Smoke 2007 (Cycle 16) $623,593
Brentwood Biomedical Research Institute Research Project Awards

Alpha4* Nicotinic Receptor in Dopaminergic System 2007 (Cycle 16) $75,000
California Institute of Technology Postdoctoral Fellowship Awards

Neural mechanisms underlying nicotine as a 'gateway' drug 2007 (Cycle 16) $60,000
University of California, Irvine Dissertation Awards

2006 (Cycle 15)
Nicotine Receptors: Role in Nicotine Addiction 2006 (Cycle 15) $20,748
California Institute of Technology Postdoctoral Fellowship Awards

Genes affecting nicotine response in C. elegans 2006 (Cycle 15) $100,000
University of California, San Diego Research Project Awards

Nicotinic Regulation of GABAergic Signaling 2006 (Cycle 15) $70,120
University of California, San Diego New Investigator Awards

Effects of nicotine on schizophrenia-like cognitive deficits 2006 (Cycle 15) $58,298
University of California, San Diego Dissertation Awards

Neurobiological substrates of nicotine addiction 2006 (Cycle 15) $419,503
University of California, San Diego Research Project Awards

2005 (Cycle 14)
Nicotine's effects on uterine artery contractillity 2005 (Cycle 14) $73,878
Loma Linda University Postdoctoral Fellowship Awards

Do receptors mediate the effects of nicotine on anxiety? 2005 (Cycle 14) $291,060
Salk Institute for Biological Studies New Investigator Awards

Bupropion and nicotine dependence: behavior & neurochemisty 2005 (Cycle 14) $37,500
Scripps Research Institute Postdoctoral Fellowship Awards

Development of nicotine withdrawal measures 2005 (Cycle 14) $50,956
University of California, San Diego Inno Dev & Exp Awards (IDEAS)

Cell adhesion at nicotinic synapses 2005 (Cycle 14) $59,454
University of California, San Diego Dissertation Awards

Micro RNA and dopamine-induced dentritic protein synthesis 2005 (Cycle 14) $59,000
California Institute of Technology Dissertation Awards

Development of nicotine withdrawal measures 2005 (Cycle 14) $91,173
Scripps Research Institute Inno Dev & Exp Awards (IDEAS)

Bupropion and nicotine dependence: behavior & neurochemisty 2005 (Cycle 14) $37,000
University of California, San Diego Postdoctoral Fellowship Awards

Nicotine synapse formation in the hippocampus 2005 (Cycle 14) $59,500
University of California, San Diego Dissertation Awards

Conformationally constrained nicotine vaccines 2005 (Cycle 14) $778,921
Scripps Research Institute Research Project Awards

2004 (Cycle 13)
Regulation of nicotinic signaling 2004 (Cycle 13) $20,499
University of California, San Diego Postdoctoral Fellowship Awards

Nicotinic receptors at GABAergic synapses in the hippocampus 2004 (Cycle 13) $75,000
University of California, San Diego Postdoctoral Fellowship Awards

Nicotine effects on gene expression and metaplasticity 2004 (Cycle 13) $74,500
Stanford University Postdoctoral Fellowship Awards

2003 (Cycle 12)
Nicotine self-administration in an animal model 2003 (Cycle 12) $660,156
Scripps Research Institute Research Project Awards

Controlled study of withdrawal symptoms in teen smokers 2003 (Cycle 12) $499,890
Stanford University Research Project Awards

A novel FMRI smoking craving and reward paradigm 2003 (Cycle 12) $96,949
University of California, Los Angeles Inno Dev & Exp Awards (IDEAS)

The eff of nicot on brain activity & neurocognition in schiz 2003 (Cycle 12) $167,964
University of California, Irvine New Investigator Awards

Hyperactive nicotine receptors 2003 (Cycle 12) $675,487
California Institute of Technology Research Project Awards

Soluble homologs of the nicotinic receptor 2003 (Cycle 12) $52,858
University of California, San Diego Dissertation Awards

Correlates of cigarette craving in acute nicotine withdrawal 2003 (Cycle 12) $17,000
University of California, Los Angeles Research Project Awards

Neuropharmacology of nicotine relapse 2003 (Cycle 12) $149,175
Cedars-Sinai Medical Center New Investigator Awards

Regulatory genes of nicotine adaptation in C.elegans 2003 (Cycle 12) $70,000
University of California, San Diego Postdoctoral Fellowship Awards

Neurobiological substrates of nicotine addiction 2003 (Cycle 12) $723,613
Scripps Research Institute Research Project Awards

Correlates of cigarette craving in acute nicotine withdrawal 2003 (Cycle 12) $517,818
Brentwood Biomedical Research Institute Research Project Awards

Individual and gender differences in nicotine sensitivity 2003 (Cycle 12) $69,495
University of California, Irvine Postdoctoral Fellowship Awards

2002 (Cycle 11)
Irritant and analgesic effects of nicotine 2002 (Cycle 11) $226,650
University of California, Davis Research Project Awards

Smoking induced dopamine release: buproprion effects 2002 (Cycle 11) $659,060
Brentwood Biomedical Research Institute Research Project Awards

Brain imaging in nicotine addiction 2002 (Cycle 11) $419,881
University of California, Los Angeles Research Project Awards

Nicotinic receptors and Parkinson's disease 2002 (Cycle 11) $376,470
The Parkinson's Institute Research Project Awards

Immunopharmacotherapy as a treatment for nicotine addiction 2002 (Cycle 11) $515,270
Scripps Research Institute Research Project Awards

Effect of cigarette smoke and nicotine on taste processing 2002 (Cycle 11) $70,000
University of California, Davis Postdoctoral Fellowship Awards

Modeling sleep disturbance during nicotine withdrawal 2002 (Cycle 11) $424,344
SRI International New Investigator Awards

Nicotinic receptors on hippocampal neurons 2002 (Cycle 11) $69,940
University of California, San Diego Postdoctoral Fellowship Awards

Neuroadaptations underlying nicotine dependence 2002 (Cycle 11) $60,379
Scripps Research Institute Postdoctoral Fellowship Awards

2001 (Cycle 10)
Neuronal nicotinic receptor trafficking in nicotine addictio 2001 (Cycle 10) $71,664
California Institute of Technology Postdoctoral Fellowship Awards

Nicotine withdrawal, smoking & attention: an fMRI study 2001 (Cycle 10) $515,303
University of California, Los Angeles Research Project Awards

Neurobehavioral consequences of adolescent nicotine exposure 2001 (Cycle 10) $630,710
Scripps Research Institute Research Project Awards

Cardiovascular responses through spinal nicotinic receptors 2001 (Cycle 10) $448,941
University of California, San Diego Research Project Awards

Effects of nicotine withdrawal on aviator performance 2001 (Cycle 10) $515,243
Stanford University Research Project Awards

Nicotinic receptors & synaptic aging 2001 (Cycle 10) $224,973
University of California, San Diego New Investigator Awards

Nicotine dependence & schizophrenia 2001 (Cycle 10) $75,600
Scripps Research Institute Postdoctoral Fellowship Awards

Effects of nicotine on taste processing 2001 (Cycle 10) $24,834
University of California, Davis Dissertation Awards

Molecular neurobiology of nicotine addiction 2001 (Cycle 10) $263,298
University of California, Los Angeles Research Project Awards

Contributions of CNRs to nicotinic signaling 2001 (Cycle 10) $70,000
University of California, San Diego Postdoctoral Fellowship Awards

Assessing nicotine relapse in a mouse model 2001 (Cycle 10) $183,804
SRI International New Investigator Awards

Neurobiological substrates of nicotine addiction 2001 (Cycle 10) $402,852
Scripps Research Institute Research Project Awards

2000 (Cycle 9)
Behavioral effects of neonatal nicotine exposure 2000 (Cycle 9) $624,780
San Diego State University Research Foundation Research Project Awards

Stress and the use of nicotine 2000 (Cycle 9) $897,484
Cedars-Sinai Medical Center Research Project Awards

Cell-cell interact reg distrib of nic receptrs on neurons 2000 (Cycle 9) $29,754
University of California, San Diego Postdoctoral Fellowship Awards

Human neurophysiology of nicotine analgesia: sex differences 2000 (Cycle 9) $595,994
University of California, San Francisco Research Project Awards

Nicotine in the Brain 2000 (Cycle 9) $518,966
University of California, San Diego Research Project Awards

Hyperactive nicotine receptors 2000 (Cycle 9) $1,138,225
California Institute of Technology Research Project Awards

Impact of nicotinic signaling on neuronal gene expression 2000 (Cycle 9) $30,055
University of California, San Diego Dissertation Awards

Neurobehavioral consequences of adolescent nicotine exposure 2000 (Cycle 9) $120,000
Scripps Research Institute Research Project Awards

Mechanism of apparent long-term nicotinic inactivation 2000 (Cycle 9) $20,565
University of California, Riverside Dissertation Awards

Nicotine regulation of the noradrenergic system 2000 (Cycle 9) $52,375
University of California, Irvine Dissertation Awards

Novel nicotine cessation therapeutics 2000 (Cycle 9) $802,840
Human BioMolecular Research Institute Research Project Awards

Nicotinic and Schizophrenia 2000 (Cycle 9) $87,719
University of California, Irvine Research Project Awards

Proteins involved in nicotine receptor clustering 2000 (Cycle 9) $307,246
University of California, San Diego Research Project Awards

Effects of prenatal nicotine exposure on nicotinic receptors 2000 (Cycle 9) $471,654
University of California, San Francisco Research Project Awards

1999 (Cycle 8)
Smoking, gender, hormones and the brain 1999 (Cycle 8) $69,084
University of California, Los Angeles Inno Dev & Exp Awards (IDEAS)

Nicotine May Affect Inflammation 1999 (Cycle 8) $435,425
University of California, San Francisco Research Project Awards

Nicotinic modulation of dopamine release during development 1999 (Cycle 8) $25,698
University of California, Irvine Dissertation Awards

Effectiveness of two different regimens in smoking clinic 1999 (Cycle 8) $272,989
University of California, Los Angeles Research Project Awards

Nicotine effects on neurological development 1999 (Cycle 8) $189,233
University of California, Irvine Research Project Awards

Role of nicotine in neuro protection 1999 (Cycle 8) $722,263
The Parkinson's Institute Research Project Awards

Neurotoxic effects of nicotine: anatomy, mechanisms, effects 1999 (Cycle 8) $183,424
University of California, Los Angeles Research Project Awards

African Americans and Mentholated Cigarettes 1999 (Cycle 8) $417,968
Charles R. Drew University of Medicine & Science Research Project Awards

Neurotransmitter systems and tobacco smoking 1999 (Cycle 8) $430,910
University of California, Los Angeles Research Project Awards

Effects of Nicotine on Brain Development 1999 (Cycle 8) $55,404
Cedars-Sinai Medical Center Dissertation Awards

1998 (Cycle 7)
11th National Conference on Nicotine Dependence 1998 (Cycle 7) $12,000
American Society of Addiction Medicine Special Projects

The role of nitric oxide in nicot induced muscle cell death 1998 (Cycle 7) $68,011
The Parkinson's Institute Postdoctoral Fellowship Awards

Bupropion for smoking cessation 1998 (Cycle 7) $471,154
University of California, San Francisco Research Project Awards

Neuroendocrine responses to nicotine: a physiologic probe 1998 (Cycle 7) $225,000
University of California, San Francisco New Investigator Awards

Clinical pharmacology of tobacco alkaloids 1998 (Cycle 7) $439,882
University of California, San Francisco Research Project Awards

Role of nicotine/nicotinic receptors in Parkinson's disease 1998 (Cycle 7) $644,770
The Parkinson's Institute Research Project Awards

Nicotine replacement therapy: pharmacists' counseling role 1998 (Cycle 7) $113,929
SRI International Inno Dev & Exp Awards (IDEAS)

Effects of Selegiline on craving for nicotine 1998 (Cycle 7) $100,450
Stanford University Research Project Awards

Neurobiological substrates of nicotine addiction 1998 (Cycle 7) $742,393
Scripps Research Institute Research Project Awards

Structural determinants of alpha-toxin: nAChR interactions 1998 (Cycle 7) $70,000
University of California, San Diego Postdoctoral Fellowship Awards

Mechanism of stress effects on weight in nicotine withdrawal 1998 (Cycle 7) $407,019
University of California, San Francisco Research Project Awards

Brain metabolic changes with cigarette craving 1998 (Cycle 7) $250,850
Brentwood Biomedical Research Institute New Investigator Awards

1997 (Cycle 6)
Functional MRI of neural activation 1997 (Cycle 6) $48,447
University of California, Los Angeles Inno Dev & Exp Awards (IDEAS)

Nicotine toxicity acting on cardiac neurons 1997 (Cycle 6) $446,920
University of California, San Diego Research Project Awards

Transdermal nicotine replacement for hospitalized smokers 1997 (Cycle 6) $451,969
University of California, San Francisco Research Project Awards

The role of nicotine receptors in nicotine dependence 1997 (Cycle 6) $381,317
University of California, Irvine Research Project Awards

Effects of perinatal nicotine on the Brain 1997 (Cycle 6) $93,122
LA Biomedical Research Institute at Harbor-UCLA Medical Center Inno Dev & Exp Awards (IDEAS)

Hyperactive nicotine receptors 1997 (Cycle 6) $486,158
California Institute of Technology Research Project Awards

Brain adaptations to chronic nicotine expsoure 1997 (Cycle 6) $402,111
University of California, Irvine Research Project Awards

Nicotine pharmacogenetics: influence of ethnicity 1997 (Cycle 6) $242,344
Cedars-Sinai Medical Center Research Project Awards

Brain wave assessment of tobacco cessation readiness 1997 (Cycle 6) $115,487
Scripps Research Institute New Investigator Awards

Nicotine pharmacogenetics: influence of ethnicity 1997 (Cycle 6) $366,244
LA Biomedical Research Institute at Harbor-UCLA Medical Center Research Project Awards

Analysis of a nicotine-related receptor binding site 1997 (Cycle 6) $69,218
University of California, San Francisco Postdoctoral Fellowship Awards

NRT and paroxetine for smoking cessation 1997 (Cycle 6) $646,916
Stanford University Research Project Awards

Irritant and pain-reducing effects of nicotine 1997 (Cycle 6) $415,704
University of California, Davis Research Project Awards

The biological basis of nicotine addiction 1997 (Cycle 6) $224,949
University of California, Riverside New Investigator Awards

Nicotonic receptors: role in addiction and reproduction 1997 (Cycle 6) $437,480
Salk Institute for Biological Studies Research Project Awards

Cardiovascular responses to nicotine 1997 (Cycle 6) $430,843
University of California, San Diego Research Project Awards

Aggression and Nicotine 1997 (Cycle 6) $230,826
University of California, Irvine Research Project Awards

1995 (Cycle 4)
Regulation of Nicotinic Receptors on Neurons by Muscle 1995 (Cycle 4) $37,783
University of California, San Diego Postdoctoral Fellowship Awards

-Heterologous Expression of Brain Nicotinic Acetylcholine Re 1995 (Cycle 4) $598,774
California Institute of Technology Research Project Awards

Nicotine Interactions with Central Stress Circuitry 1995 (Cycle 4) $69,120
Salk Institute for Biological Studies Postdoctoral Fellowship Awards

1994 (Cycle 3)
The Dopamine D2 Receptor in Nicotine Addiction 1994 (Cycle 3) $162,870
City of Hope National Medical Center Research Project Awards

Nicotinic Receptor Biology in CNS Neurons: An in vitro Model 1994 (Cycle 3) $225,000
University of California, San Diego New Investigator Awards

Acetylcholine Receptors in the Developing Nervous System 1994 (Cycle 3) $116,263
University of California, San Diego Research Project Awards

Molecular Mechanisms of Brain Nicotinic Receptor Inactivatn 1994 (Cycle 3) $42,567
California Institute of Technology Postdoctoral Fellowship Awards

Desensitization of Cholinergic Mechanisms & Nicotine Addictn 1994 (Cycle 3) $267,178
University of California, Davis Research Project Awards

1993 (Cycle 2)
Nicotine, Tobacco Smoke and the Blood-Brain Barrier 1993 (Cycle 2) $624,017
University of Southern California Research Project Awards

Neuronal ACh Receptors: Candidates for Mediating Addiction 1993 (Cycle 2) $66,994
University of California, San Diego Postdoctoral Fellowship Awards

Nicotinic Receptors, Tolerance and Spinal Neurotransmitters 1993 (Cycle 2) $320,869
University of California, San Diego Research Project Awards

Human Markers for(S)-Nicotine Biotransformation & Pathology 1993 (Cycle 2) $58,899
University of California, San Francisco Inno Dev & Exp Awards (IDEAS)

CNS effects of prenatal nicotine exposure: threshold dosage 1993 (Cycle 2) $458,763
LA Biomedical Research Institute at Harbor-UCLA Medical Center Research Project Awards

A Hypothalamic Mechanism of Nicotine Reward and Addiction 1993 (Cycle 2) $61,640
University of California, San Diego Inno Dev & Exp Awards (IDEAS)

Nicotine Addiction: Novel ACh Receptors on Neurons 1993 (Cycle 2) $369,025
University of California, San Diego Research Project Awards

Nicotine-induced Changes in Gene Expression 1993 (Cycle 2) $70,000
University of California, San Diego Postdoctoral Fellowship Awards

Vascular Effects of Nicotine: Effect of Age 1993 (Cycle 2) $331,124
University of California, Irvine Research Project Awards

1992 (Cycle 1)
Nicotinic Effects on Gene Expression in PC-12 Cells 1992 (Cycle 1) $266,647
University of California, San Diego Research Project Awards

Nicotine Effects on Activity of Brain Catecholamine Neurons 1992 (Cycle 1) $317,443
University of California, San Diego Research Project Awards

Nicotine Enhanced Adrenal Medullary-Dependent Inflammation 1992 (Cycle 1) $363,563
University of California, San Francisco Research Project Awards

Nicotine & Early Response Gene Expression in Brain 1992 (Cycle 1) $99,290
University of California, San Francisco Research Project Awards

Regulation of the Nicotinic Receptors by Nicotine 1992 (Cycle 1) $756,102
Salk Institute for Biological Studies Research Project Awards

Effects of Sedatives on Neuronal Nicotinic Binding 1992 (Cycle 1) $394,301
University of California, San Francisco Research Project Awards

Molecular Dynamics of Acetylcholinesterase Mutants 1992 (Cycle 1) $70,000
University of California, San Diego Postdoctoral Fellowship Awards

Heterologous Expression of Brain Nicotinic Receptors 1992 (Cycle 1) $586,840
California Institute of Technology Research Project Awards

The Accumbens: A Critical Brain Site for Nicotine Craving 1992 (Cycle 1) $532,964
Scripps Research Institute Research Project Awards